Aliases for TRPC2 Gene

Aliases for TRPC2 Gene

  • Transient Receptor Potential Cation Channel Subfamily C Member 2 (Pseudogene) 2 3 5
  • Transient Receptor Potential Cation Channel, Subfamily C, Member 2, Pseudogene 2
  • Transient Receptor Potential Cation Channel, Subfamily C, Member 2 2
  • Transient Receptor Potential Channel 2 (Pseudogene) 3
  • TRPC2 5

External Ids for TRPC2 Gene

Previous GeneCards Identifiers for TRPC2 Gene

  • GC11P004223
  • GC11U900038
  • GC11P003607
  • GC11P003601
  • GC11P003611
  • GC11P003385

Summaries for TRPC2 Gene

GeneCards Summary for TRPC2 Gene

TRPC2 (Transient Receptor Potential Cation Channel Subfamily C Member 2 (Pseudogene)) is a Pseudogene. Among its related pathways are CREB Pathway.

Gene Wiki entry for TRPC2 Gene

Additional gene information for TRPC2 Gene

No data available for Entrez Gene Summary , CIViC Summary , UniProtKB/Swiss-Prot Summary , Tocris Summary , PharmGKB "VIP" Summary , Rfam classification and piRNA Summary for TRPC2 Gene

Genomics for TRPC2 Gene

GeneHancer (GH) Regulatory Elements Pubs

Promoters and enhancers for TRPC2 Gene
GeneHancer (GH) Identifier GH Type GH
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH11J003609 Enhancer 0.6 ENCODE 600.7 0.0 -35 0.2 CTCF REST RAD21 TRIM22 SMC3 GATA3 ZNF654 ZNF143 KLF16 YY1 LOC115995503 TRPC2 piR-32214-071 ART5 ART1 ENSG00000255367 MG828483 LOC105376526
GH11J002897 Promoter/Enhancer 2.6 EPDnew FANTOM5 Ensembl ENCODE CraniofacialAtlas dbSUPER 4.7 -708.5 -708454 7.3 RNF2 ARHGAP35 SP1 HNRNPL GATAD2A PRDM10 ZNF629 LEF1 IKZF1 BACH1 SLC22A18 SLC22A18AS KCNQ1 TRPC2 MN297025
GH11J003626 Promoter/Enhancer 0.9 Ensembl ENCODE 9.6 +17.2 17249 1.9 CTCF NRF1 FOSL1 BHLHE40 SPI1 ELF1 GLIS1 POLR2A TEAD2 ZFX ART5 TRPC2 piR-32214-071 LOC105376526
GH11J003622 Enhancer 0.3 Ensembl 8.6 +13.2 13200 0.6 IKZF1 TRPC2 ART5 piR-32214-071 LOC105376526
GH11J003614 Enhancer 0.9 FANTOM5 ENCODE 0.4 +5.0 5006 1.7 RELA ZIC2 MTA1 HDAC1 PKNOX1 CTBP1 RUNX3 HES1 RUNX1 MBD2 ART5 ART1 ENSG00000255367 NUP98 RHOG LOC115995503 piR-32214-071 TRPC2 LOC105376526
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data from 2017 publication | Request up-to-date GeneHancer data (full dataset)

GeneHancers around TRPC2 on the GeneHancer Hub at the UCSC Golden Path

Top Transcription factor binding sites by QIAGEN in the TRPC2 gene promoter:
  • AhR
  • AP-1
  • c-Fos
  • c-Jun
  • ER-alpha
  • FosB
  • Fra-1
  • ISGF-3
  • JunB
  • JunD

Genomic Locations for TRPC2 Gene

Genomic Locations for TRPC2 Gene
27,659 bases
Plus strand
27,659 bases
Plus strand

Genomic View for TRPC2 Gene

Genes around TRPC2 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
TRPC2 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for TRPC2 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for TRPC2 Gene

Proteins for TRPC2 Gene

Post-translational modifications for TRPC2 Gene

No Post-translational modifications

No data available for DME Specific Peptides for TRPC2 Gene

Domains & Families for TRPC2 Gene

genes like me logo Genes that share domains with TRPC2: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences , Graphical View of Domain Structure and UniProtKB/Swiss-Prot for TRPC2 Gene

Function for TRPC2 Gene

Molecular function for TRPC2 Gene

GENATLAS Biochemistry:
transient receptor potential non voltage-channel 2,Drosophila store-operated channel (Soc) homolog,ubiquitous predominantly expressed in fetal brain,adult heart,brain,testis,ovaries,activated by calcium store depletion, component of the capacitative calcium entry,channels (homo or heterotetramer),may be a pseudogene

Phenotypes for TRPC2 Gene

genes like me logo Genes that share phenotypes with TRPC2: view

Animal Model Products

  • Taconic Biosciences Mouse Models for TRPC2

CRISPR Products

No data available for Enzyme Numbers (IUBMB) , Phenotypes From GWAS Catalog , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for TRPC2 Gene

Localization for TRPC2 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for TRPC2 Gene

Pathways & Interactions for TRPC2 Gene

PathCards logo

SuperPathways for TRPC2 Gene

SuperPathway Contained pathways
1 CREB Pathway
genes like me logo Genes that share pathways with TRPC2: view

Pathways by source for TRPC2 Gene

1 Qiagen pathway for TRPC2 Gene
  • Intracellular Calcium Signaling

Gene Ontology (GO) - Biological Process for TRPC2 Gene


No data available for Interacting Proteins and SIGNOR curated interactions for TRPC2 Gene

Drugs & Compounds for TRPC2 Gene

No Compound Related Data Available

Transcripts for TRPC2 Gene

mRNA/cDNA for TRPC2 Gene

3 NCBI additional mRNA sequence :
2 Ensembl transcripts including schematic representations, and UCSC links to gene/alias where relevant :

CRISPR Products

Alternative Splicing Database (ASD) splice patterns (SP) for TRPC2 Gene

No ASD Table

Relevant External Links for TRPC2 Gene

GeneLoc Exon Structure for

Expression for TRPC2 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and SAGE for TRPC2 Gene

mRNA differential expression in normal tissues according to GTEx for TRPC2 Gene

This gene is overexpressed in Spleen (x4.1) and Whole Blood (x4.1).

Transcriptomic regulation report from SPP (The Signaling Pathways Project) for TRPC2

SOURCE GeneReport for Unigene cluster for TRPC2 Gene:

genes like me logo Genes that share expression patterns with TRPC2: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for TRPC2 Gene

Orthologs for TRPC2 Gene

Evolution for TRPC2 Gene

Gene Tree for TRPC2 (if available)
Gene Tree for TRPC2 (if available)

No data available for Orthologs for TRPC2 Gene

Paralogs for TRPC2 Gene

No data available for Paralogs for TRPC2 Gene

Variants for TRPC2 Gene

Structural Variations from Database of Genomic Variants (DGV) for TRPC2 Gene

Variant ID Type Subtype PubMed ID
dgv186e199 CNV deletion 23128226
esv2658889 CNV deletion 23128226
esv2662660 CNV deletion 23128226
esv2675176 CNV deletion 23128226
esv2678063 CNV deletion 23128226
esv2744037 CNV deletion 23290073
esv2759796 CNV gain+loss 17122850
esv2760179 CNV loss 21179565
esv2760300 CNV gain 21179565
esv28322 CNV gain+loss 19812545
esv3547237 CNV deletion 23714750
esv3547238 CNV deletion 23714750
esv3625147 CNV gain 21293372
esv3625148 CNV gain 21293372
esv3625149 CNV loss 21293372
esv3625150 CNV loss 21293372
esv3625151 CNV loss 21293372
esv3625152 CNV loss 21293372
nsv1045810 CNV gain 25217958
nsv1046356 CNV gain 25217958
nsv1140120 CNV insertion 24896259
nsv1149571 CNV insertion 26484159
nsv428247 CNV loss 18775914
nsv467660 CNV gain 19166990
nsv509385 CNV insertion 20534489
nsv526441 CNV gain 19592680
nsv553140 CNV gain 21841781
nsv825717 CNV loss 20364138
nsv832051 CNV gain 17160897
nsv832052 CNV loss 17160897

Additional Variant Information for TRPC2 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for

SNP Genotyping and Copy Number Assay Products

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Sequence variations, with clinical significance, from ClinVar and Humsavar, with links to dbSNP , Additional dbSNP identifiers (rs#s) and Variation tolerance for TRPC2 Gene

Disorders for TRPC2 Gene

Additional Disease Information for TRPC2

No disorders were found for TRPC2 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for TRPC2 Gene

Publications for TRPC2 Gene

  1. TRPC2: molecular biology and functional importance. (PMID: 17217050) Yildirim E … Birnbaumer L (Handbook of experimental pharmacology 2007) 2 3
  2. International Union of Pharmacology. XLIX. Nomenclature and structure-function relationships of transient receptor potential channels. (PMID: 16382100) Clapham DE … Schultz G (Pharmacological reviews 2005) 2 3
  3. TRPC1, a human homolog of a Drosophila store-operated channel. (PMID: 7568191) Wes PD … Montell C (Proceedings of the National Academy of Sciences of the United States of America 1995) 2 3
  4. TRPC2. (PMID: 24756702) Miller BA (Handbook of experimental pharmacology 2014) 3
  5. Identification and analysis of unitary pseudogenes: historic and contemporary gene losses in humans and other primates. (PMID: 20210993) Zhang ZD … Gerstein M (Genome biology 2010) 3

Products for TRPC2 Gene

Sources for TRPC2 Gene