Aliases for TRIM7 Gene
External Ids for TRIM7 Gene
Previous GeneCards Identifiers for TRIM7 Gene
The protein encoded by this gene is a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1, a B-box type 2, and a coiled-coil region. The protein localizes to both the nucleus and the cytoplasm, and may represent a participant in the initiation of glycogen synthesis. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2013]
GeneCards Summary for TRIM7 Gene
TRIM7 (Tripartite Motif Containing 7) is a Protein Coding gene. An important paralog of this gene is TRIM27.
UniProtKB/Swiss-Prot for TRIM7 Gene
E3 ubiquitin-protein ligase. Mediates Lys-63-linked polyubiquitination and stabilization of the JUN coactivator RNF187 in response to growth factor signaling via the MEK/ERK pathway, thereby regulating JUN transactivation and cellular proliferation.