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Aliases for TRIM65 Gene
Aliases for TRIM65 Gene
External Ids for TRIM65 Gene
- HGNC: 27316
- Entrez Gene: 201292
- Ensembl: ENSG00000141569
- UniProtKB: Q6PJ69
Previous GeneCards Identifiers for TRIM65 Gene
- GC17M071397
- GC17M073885
- GC17M069310
Summaries for TRIM65 Gene
GeneCards Summary for TRIM65 Gene
TRIM65 (Tripartite Motif Containing 65) is a Protein Coding gene. An important paralog of this gene is TRIM47.
Additional gene information for TRIM65 Gene
- Monarch Initiative
- Search for TRIM65 at DataMed
- Search for TRIM65 at HumanCyc
No data available for Entrez Gene Summary , CIViC Summary , UniProtKB/Swiss-Prot Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , Rfam classification and piRNA Summary for TRIM65 Gene
Genomics for TRIM65 Gene
GeneHancer (GH) Regulatory Elements for TRIM65 Gene
Promoters and enhancers for TRIM65 Gene
- Elite GeneHancer and/or Elite GeneHancer-gene association
Download GeneHancer data from 2017 publication |
Request up-to-date GeneHancer data (full dataset)
GeneHancers around TRIM65 on UCSC Golden Path with GeneCards custom track
- Top Transcription factor binding sites by QIAGEN in the TRIM65 gene promoter:
-
- AhR
- AML1a
- Egr-2
- Egr-4
- ER-alpha
- GATA-2
- HOXA5
- ITF-2
- PPAR-alpha
- Tal-1beta
Genomic Locations for TRIM65 Gene
Genomic Locations for TRIM65 Gene
- chr17:75,880,335-75,897,003
- (GRCh38/hg38)
- Size:
- 16,669 bases
- Orientation:
- Minus strand
- chr17:73,876,416-73,893,084
- (GRCh37/hg19)
- Size:
- 16,669 bases
- Orientation:
- Minus strand
Genomic View for TRIM65 Gene
Genes around TRIM65 on UCSC Golden Path with GeneCards custom track
- Cytogenetic band:
-
- 17q25.1 by HGNC
- 17q25.1 by Entrez Gene
- 17q25.1 by Ensembl
TRIM65 Gene in genomic location: bands according to
Ensembl, locations according to GeneLoc
(and/or Entrez Gene and/or Ensembl if different)
Genomic Neighborhood
• Exon Structure
• Gene Density
RefSeq DNA sequence for TRIM65 Gene
Proteins for TRIM65 Gene
-
Protein details for TRIM65 Gene (UniProtKB/Swiss-Prot)
- Protein Symbol:
- Q6PJ69-TRI65_HUMAN
- Recommended name:
- Tripartite motif-containing protein 65
- Protein Accession:
- Q6PJ69
- Q4G0F0
- Q6DKJ6
- Q9BRP6
Protein attributes for TRIM65 Gene
- Size:
- 517 amino acids
- Molecular mass:
- 57353 Da
- Quaternary structure:
- No Data Available
- SequenceCaution:
-
- Sequence=AAH73831.1; Type=Erroneous initiation; Note=Translation N-terminally shortened.; Evidence={ECO:0000305};
Protein Expression for TRIM65 Gene
Post-translational modifications for TRIM65 Gene
Other Protein References for TRIM65 Gene
Antibody Products
- Atlas Antibodies Anti-TRIM65 Antibody (HPA021578), Anti-TRIM65 Antibody (HPA021575), and Anti-TRIM65 Antibody (HPA064820)
- Creative Diagnostics Anti-TRIM65 monoclonal antibody, Anti-TRIM65 (aa 334-364) polyclonal antibody, and Anti-TRIM65 polyclonal antibody
- Novus Biologicals Antibodies for TRIM65
-
Abcam antibodies for TRIM65
- Invitrogen Antibodies for TRIM65 (AFLGC-TRIM65)
- antibodies-online: Show 12 available TRIM65 Antibodies ranked by validation data
-
Biorbyt antibodies for TRIM65
Protein Products
- Creative Biomart Recombinant Human TRIM65 cell lysate
- Search Origene for Purified Proteins, MassSpec and Protein Over-expression Lysates for TRIM65
- Origene Custom Protein Services for TRIM65
-
Abcam proteins for TRIM65
No data available for DME Specific Peptides for TRIM65 Gene
Domains & Families for TRIM65 Gene
Gene Families for TRIM65 Gene
- HGNC:
- Human Protein Atlas (HPA):
-
- Predicted intracellular proteins
Protein Domains for TRIM65 Gene
Suggested Antigen Peptide Sequences for TRIM65 Gene
- GenScript: Design optimal peptide antigens:
-
- TRIM65 protein (Q96DX1_HUMAN)
- Tripartite motif-containing protein 65 (TRI65_HUMAN)
Graphical View of Domain Structure for InterPro Entry
Q6PJ69- Family:
-
- Belongs to the TRIM/RBCC family.
Function for TRIM65 Gene
Phenotypes From GWAS Catalog for TRIM65 Gene
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0008270 | zinc ion binding | IEA | -- |
| GO:0046872 | metal ion binding | IEA | -- |
Phenotypes for TRIM65 Gene
- MGI mutant phenotypes for TRIM65:
- inferred from 1 alleles
- GenomeRNAi human phenotypes for TRIM65:
Animal Models for TRIM65 Gene
- MGI Knock Outs for TRIM65:
-
- Trim65 Trim65<tm1b(KOMP)Wtsi>
Animal Model Products
- Taconic Biosciences: Generate A Custom CRISPR Mouse Model For Your Study
CRISPR Products
-
OriGene CRISPR knockouts for TRIM65
- Search GeneCopoeia for CRISPR/Cas9 clones, lentivirus and AAV products for TRIM65
- genomics-online: gRNA clones - Search for available TRIM65 gRNA products
- Overview of 96 available TRIM65 gene related products
- Applied Biological Materials (abm): CRISPR Clones for TRIM65 - Select products 50% OFF >
- * TRIM65 CRISPR as ready-to-use vector or virus: ORF | Lenti- | Adeno- | AAV- | Protein Vector - Browse All
- * TRIM65 CRISPR applications: KO, Activation, Repression, and more - Browse All
-
Santa Cruz Biotechnology (SCBT) CRISPR for TRIM65
miRNA for TRIM65 Gene
- miRTarBase miRNAs that target TRIM65
-
- hsa-mir-124-3p (MIRT022681)
- hsa-mir-122-5p (MIRT023281)
- hsa-mir-26b-5p (MIRT029564)
- hsa-mir-484 (MIRT042378)
- hsa-mir-324-3p (MIRT042948)
- hsa-mir-331-3p (MIRT043464)
- hsa-mir-93-5p (MIRT048856)
- hsa-mir-218-5p (MIRT439389)
- hsa-mir-665 (MIRT626700)
- hsa-mir-8055 (MIRT626701)
- hsa-mir-6780a-5p (MIRT626702)
- hsa-mir-6779-5p (MIRT626703)
- hsa-mir-3689c (MIRT626704)
- hsa-mir-3689b-3p (MIRT626705)
- hsa-mir-3689a-3p (MIRT626706)
- hsa-mir-30b-3p (MIRT626707)
- hsa-mir-1273h-5p (MIRT626708)
- hsa-mir-4443 (MIRT626709)
- hsa-mir-516b-5p (MIRT626710)
- hsa-mir-6778-5p (MIRT626711)
- hsa-mir-1233-5p (MIRT626712)
- hsa-mir-6799-5p (MIRT626713)
- hsa-mir-6883-5p (MIRT626714)
- hsa-mir-6785-5p (MIRT626715)
- hsa-mir-4728-5p (MIRT626716)
- hsa-mir-149-3p (MIRT626717)
- hsa-mir-7106-5p (MIRT626718)
- hsa-mir-650 (MIRT626719)
- hsa-mir-3612 (MIRT626720)
- hsa-mir-6894-5p (MIRT626721)
- hsa-mir-6134 (MIRT626722)
- hsa-mir-7854-3p (MIRT626723)
- hsa-mir-6884-5p (MIRT626724)
- hsa-mir-485-5p (MIRT626725)
- hsa-mir-3670 (MIRT626726)
- hsa-mir-518c-5p (MIRT626727)
- hsa-mir-3121-5p (MIRT626728)
- hsa-mir-501-5p (MIRT626729)
- hsa-mir-4661-3p (MIRT626730)
- hsa-mir-514a-5p (MIRT626731)
- hsa-mir-498 (MIRT649239)
- hsa-mir-6783-3p (MIRT649240)
- hsa-mir-1343-3p (MIRT649241)
- hsa-mir-23b-5p (MIRT649242)
- hsa-mir-23a-5p (MIRT649243)
- hsa-mir-4772-3p (MIRT649244)
- hsa-mir-6787-3p (MIRT649245)
- hsa-mir-1304-3p (MIRT649246)
- hsa-mir-6742-3p (MIRT649247)
- hsa-mir-6852-5p (MIRT649248)
- hsa-mir-660-3p (MIRT649249)
- hsa-mir-6736-3p (MIRT649250)
- hsa-mir-6890-3p (MIRT649251)
- hsa-mir-1306-5p (MIRT649252)
- hsa-mir-216a-5p (MIRT649254)
- hsa-mir-7160-5p (MIRT664655)
- hsa-mir-610 (MIRT664656)
- hsa-mir-7162-3p (MIRT664657)
- hsa-mir-4478 (MIRT664658)
- hsa-mir-4419b (MIRT664659)
- hsa-mir-3929 (MIRT664660)
- hsa-mir-3664-5p (MIRT664661)
- hsa-mir-4714-5p (MIRT664662)
- hsa-mir-8070 (MIRT677569)
- hsa-mir-6848-3p (MIRT677570)
- hsa-mir-6843-3p (MIRT677571)
- hsa-mir-3187-3p (MIRT677572)
- hsa-mir-4435 (MIRT677573)
- hsa-mir-588 (MIRT677574)
- hsa-mir-4701-5p (MIRT677575)
- hsa-mir-548s (MIRT677576)
- hsa-mir-378a-5p (MIRT677577)
- hsa-mir-6131 (MIRT677578)
- hsa-mir-4763-5p (MIRT677579)
- hsa-mir-4755-3p (MIRT677580)
- hsa-mir-4454 (MIRT677581)
- hsa-mir-6759-3p (MIRT677582)
- hsa-mir-3653-5p (MIRT677583)
- hsa-mir-3663-5p (MIRT677584)
- hsa-mir-6747-3p (MIRT677585)
- hsa-mir-4485-5p (MIRT677586)
- hsa-mir-106a-5p (MIRT761128)
- hsa-mir-106b-5p (MIRT761136)
- hsa-mir-1273g-3p (MIRT761998)
- hsa-mir-150-5p (MIRT762879)
- hsa-mir-17-5p (MIRT762958)
- hsa-mir-186-3p (MIRT763199)
- hsa-mir-20a-5p (MIRT763765)
- hsa-mir-20b-5p (MIRT763777)
- hsa-mir-302a-3p (MIRT764447)
- hsa-mir-302b-3p (MIRT764468)
- hsa-mir-302c-3p (MIRT764485)
- hsa-mir-302d-3p (MIRT764500)
- hsa-mir-302e (MIRT764516)
- hsa-mir-372-3p (MIRT767245)
- hsa-mir-373-3p (MIRT767288)
- hsa-mir-4252 (MIRT768062)
- hsa-mir-4731-5p (MIRT771787)
- hsa-mir-5089-5p (MIRT773249)
- hsa-mir-512-3p (MIRT773357)
- hsa-mir-519d-3p (MIRT773726)
- hsa-mir-520a-3p (MIRT773759)
- hsa-mir-520b (MIRT773779)
- hsa-mir-520c-3p (MIRT773792)
- hsa-mir-520d-3p (MIRT773808)
- hsa-mir-520e (MIRT773824)
- hsa-mir-520g-3p (MIRT773852)
- hsa-mir-520h (MIRT773879)
- hsa-mir-526b-3p (MIRT773922)
- hsa-mir-5589-5p (MIRT774818)
- hsa-mir-619-5p (MIRT776062)
- hsa-mir-6506-5p (MIRT776611)
- hsa-mir-668-5p (MIRT777662)
- hsa-mir-6720-3p (MIRT777718)
- hsa-mir-6807-5p (MIRT779624)
miRNA Products
Inhibitory RNA Products
- Origene sirna, shrna, and RNAi products in human, mouse, rat for TRIM65
- Browse OriGene Inhibitory RNA Products For TRIM65
- Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for TRIM65
- genomics-online: shRNA clones - Search for available TRIM65 shRNA products
- Overview of 96 available TRIM65 gene related products
Clone Products
- Sino Biological Human cDNA Clone for TRIM65
- Addgene plasmids for TRIM65
- Search GeneCopoeia for ORF cDNA, lentivirus, AAV viral particles and/or promoter clone products for TRIM65
- genomics-online: cdna clones - Search for available TRIM65 CDNA products
- Overview of 96 available TRIM65 gene related products
- orf clones - Search for available TRIM65 ORF products
- Overview of 96 available TRIM65 gene related products
- Applied Biological Materials (abm): Clones for TRIM65 - Select products 50% OFF >
- * TRIM65 as ready-to-use vector or virus: ORF | Lenti- | Retro- | Adeno- | AAV- | Protein Vector - Browse All
- * TRIM65 tags and reporters available: His, HA, Myc, Flag, GFP, RFP, Luciferase - Browse All
Cell Line Products
-
Horizon Cell Lines for TRIM65
No data available for Molecular function , Enzyme Numbers (IUBMB) , Human Phenotype Ontology , Transcription Factor Targets and HOMER Transcription for TRIM65 Gene
Localization for TRIM65 Gene
| Compartment | Confidence |
|---|---|
| nucleus | 5 |
| cytosol | 5 |
| cytoskeleton | 1 |
- Cytosol (3)
- Nucleoplasm (3)
- Vesicles (2)
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0005634 | nucleus | IDA | -- |
| GO:0005654 | nucleoplasm | IDA | -- |
| GO:0005829 | cytosol | IDA | -- |
No data available for Subcellular locations from UniProtKB/Swiss-Prot for TRIM65 Gene
Pathways & Interactions for TRIM65 Gene
Interacting Proteins for TRIM65 Gene
Selected Interacting proteins:
Q6PJ69-TRI65_HUMAN
ENSP00000269383
for TRIM65 Gene via
MINT
STRING
IID
GPS-Prot Interaction Network for TRIM65
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0010508 | positive regulation of autophagy | IBA,IMP | 26347139 |
No data available for Pathways by source and SIGNOR curated interactions for TRIM65 Gene
Drugs & Compounds for TRIM65 Gene
No Compound Related Data Available
Transcripts for TRIM65 Gene
mRNA/cDNA for TRIM65 Gene
- (2) REFSEQ mRNAs :
- (11) Additional mRNA sequences :
- (99) Selected AceView cDNA sequences:
- (7) Ensembl transcripts including schematic representations, and UCSC links to gene/alias where relevant :
-
- ENST00000269383 3384 bps (ENST00000269383.7)
- ENST00000540128 886 bps (ENST00000540128.1)
- ENST00000540812 385 bps (ENST00000540812.1)
- ENST00000543309 865 bps (ENST00000543309.5)
- ENST00000591668 644 bps (ENST00000591668.5)
CRISPR Products
-
OriGene CRISPR knockouts for TRIM65
- Search GeneCopoeia for CRISPR/Cas9 clones, lentivirus and AAV products for TRIM65
- genomics-online: gRNA clones - Search for available TRIM65 gRNA products
- Overview of 96 available TRIM65 gene related products
- Applied Biological Materials (abm): CRISPR Clones for TRIM65 - Select products 50% OFF >
- * TRIM65 CRISPR as ready-to-use vector or virus: ORF | Lenti- | Adeno- | AAV- | Protein Vector - Browse All
- * TRIM65 CRISPR applications: KO, Activation, Repression, and more - Browse All
-
Santa Cruz Biotechnology (SCBT) CRISPR for TRIM65
miRNA Products
Inhibitory RNA Products
- Origene sirna, shrna, and RNAi products in human, mouse, rat for TRIM65
- Browse OriGene Inhibitory RNA Products For TRIM65
- Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for TRIM65
- genomics-online: shRNA clones - Search for available TRIM65 shRNA products
- Overview of 96 available TRIM65 gene related products
Clone Products
- Sino Biological Human cDNA Clone for TRIM65
- Addgene plasmids for TRIM65
- Search GeneCopoeia for ORF cDNA, lentivirus, AAV viral particles and/or promoter clone products for TRIM65
- genomics-online: cdna clones - Search for available TRIM65 CDNA products
- Overview of 96 available TRIM65 gene related products
- orf clones - Search for available TRIM65 ORF products
- Overview of 96 available TRIM65 gene related products
- Applied Biological Materials (abm): Clones for TRIM65 - Select products 50% OFF >
- * TRIM65 as ready-to-use vector or virus: ORF | Lenti- | Retro- | Adeno- | AAV- | Protein Vector - Browse All
- * TRIM65 tags and reporters available: His, HA, Myc, Flag, GFP, RFP, Luciferase - Browse All
| ExUns: | 1a | · | 1b | · | 1c | ^ | 2a | · | 2b | ^ | 3a | · | 3b | ^ | 4 | ^ | 5 | ^ | 6a | · | 6b | · | 6c |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| SP1: | - | ||||||||||||||||||||||
| SP2: | - | - | |||||||||||||||||||||
| SP3: | |||||||||||||||||||||||
| SP4: |
Expression for TRIM65 Gene
This gene is overexpressed in Serum (37.8) and Peripheral blood mononuclear cells (8.7).
Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, MaxQB, and MOPED for TRIM65 Gene
NURSA nuclear receptor signaling pathways regulating expression of TRIM65 Gene:
TRIM65SOURCE GeneReport for Unigene cluster for TRIM65 Gene:
Hs.189823Evidence on tissue expression from TISSUES for TRIM65 Gene
- Nervous system(4.3)
- Liver(4.1)
Primer Products
-
OriGene qPCR primer pairs for TRIM65
-
OriGene qPCR primer pairs and template standards for TRIM65
- genomics-online: primer clones - Search for available TRIM65 Primer products
- Overview of 96 available TRIM65 gene related products
Gene Expression Assay Products
No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , mRNA Expression by UniProt/SwissProt and Phenotype-based relationships between genes and organs from Gene ORGANizer for TRIM65 Gene
Orthologs for TRIM65 Gene
This gene was present in the common ancestor of chordates.
| Organism | Taxonomy | Gene | Similarity | Type | Details |
|---|---|---|---|---|---|
| chimpanzee (Pan troglodytes) |
Mammalia | TRIM65 33 32 |
|
OneToOne | |
| cow (Bos Taurus) |
Mammalia | TRIM65 33 32 |
|
OneToOne | |
| dog (Canis familiaris) |
Mammalia | TRIM65 33 32 |
|
OneToOne | |
| mouse (Mus musculus) |
Mammalia | Trim65 17 33 32 |
|
||
| rat (Rattus norvegicus) |
Mammalia | Trim65 32 |
|
||
| oppossum (Monodelphis domestica) |
Mammalia | TRIM65 33 |
|
OneToOne | |
| platypus (Ornithorhynchus anatinus) |
Mammalia | TRIM65 33 |
|
OneToOne | |
| chicken (Gallus gallus) |
Aves | TRIM65 32 |
|
||
| -- 33 |
|
ManyToMany | |||
| lizard (Anolis carolinensis) |
Reptilia | TRIM65 33 |
|
OneToOne | |
| tropical clawed frog (Silurana tropicalis) |
Amphibia | trim65 32 |
|
||
| zebrafish (Danio rerio) |
Actinopterygii | LOC100149099 32 |
|
||
| trim65 33 |
|
OneToOne |
- Species where no ortholog for TRIM65 was found in the sources mined by GeneCards:
-
- A. gosspyii yeast (Ashbya gossypii)
- Actinobacteria (Mycobacterium tuberculosis)
- African clawed frog (Xenopus laevis)
- African malaria mosquito (Anopheles gambiae)
- Alicante grape (Vitis vinifera)
- alpha proteobacteria (Wolbachia pipientis)
- amoeba (Dictyostelium discoideum)
- Archea (Pyrococcus horikoshii)
- baker's yeast (Saccharomyces cerevisiae)
- barley (Hordeum vulgare)
- beta proteobacteria (Neisseria meningitidis)
- bread mold (Neurospora crassa)
- Chromalveolata (Phytophthora infestans)
- common water flea (Daphnia pulex)
- corn (Zea mays)
- E. coli (Escherichia coli)
- filamentous fungi (Aspergillus nidulans)
- Firmicute bacteria (Streptococcus pneumoniae)
- fission yeast (Schizosaccharomyces pombe)
- fruit fly (Drosophila melanogaster)
- green algae (Chlamydomonas reinhardtii)
- honey bee (Apis mellifera)
- K. lactis yeast (Kluyveromyces lactis)
- loblloly pine (Pinus taeda)
- malaria parasite (Plasmodium falciparum)
- medicago trunc (Medicago Truncatula)
- moss (Physcomitrella patens)
- orangutan (Pongo pygmaeus)
- pig (Sus scrofa)
- rainbow trout (Oncorhynchus mykiss)
- rice (Oryza sativa)
- rice blast fungus (Magnaporthe grisea)
- schistosome parasite (Schistosoma mansoni)
- sea anemone (Nematostella vectensis)
- sea squirt (Ciona intestinalis)
- sea squirt (Ciona savignyi)
- sea urchin (Strongylocentrotus purpuratus)
- sorghum (Sorghum bicolor)
- soybean (Glycine max)
- stem rust fungus (Puccinia graminis)
- sugarcane (Saccharum officinarum)
- thale cress (Arabidopsis thaliana)
- tomato (Lycopersicon esculentum)
- toxoplasmosis (Toxoplasma gondii)
- Trichoplax (Trichoplax adhaerens)
- wheat (Triticum aestivum)
- worm (Caenorhabditis elegans)
Evolution for TRIM65 Gene
- ENSEMBL:
- Gene Tree for TRIM65 (if available)
- TreeFam:
- Gene Tree for TRIM65 (if available)
- Aminode:
- Evolutionary constrained regions (ECRs) for TRIM65: view image
Paralogs for TRIM65 Gene
Paralogs for TRIM65 Gene
- TRIM47 5
- TRIM67 5
- TRIM46 5
- TRIM9 5
- TRIM36 5
- TRIM11 5
- TRIM17 5
- TRIM26 5
- TRIM25 5
- TRIM41 5
- TRIM2 5
- MID1 5
- TRIM3 5
- TRIM7 5
- TRIM21 5
- TRIM5 5
- TRIM58 5
- TRIM68 5
- MID2 5
- TRIM39 5
- TRIM75P 5
- TRIM38 5
- TRIM27 5
- TRIM28 5
- TRIM10 5
- TRIM35 5
- TRIM15 5
- TRIM22 5
- TRIM6-TRIM34 5
- TRIM64C 5
- TRIM71 5
- TRIM33 5
- TRIM72 5
- TRIM64B 5
- TRIM60 5
- TRIM6 5
- TRIM62 5
- TRIM69 5
- TRIM50 5
- TRIM64 5
- TRIM4 5
- TRIM77 5
- TRIM51 5
- TRIM43B 5
- TRIM34 5
- TRIM66 5
- TRIM56 5
- TRIM24 5
- TRIM43 5
- TRIML1 5
- TRIM14 5
- TRIM49D2 5
- TRIM45 5
- TRIM49 5
- TRIM39-RPP21 5
- TRIM49C 5
- TRIM49D1 5
- TRIM32 5
- TRIM49B 5
- TRIM29 5
- TRIM51GP 5
- MEFV 5
- TRIM31 5
- TRIML2 5
- TRIM13 5
- TRIM8 5
- PML 5
- TRIM37 5
- TRIM55 5
- TRIM54 5
- TRIM42 5
- BSPRY 5
- TRIM16 5
- TRIM63 5
- TRIM48 5
- TRIM73 5
- TRIM40 5
- TRIM52 5
- TRIM74 5
- TRIM61 5
- TRIM16L 5
- TRIM44 5
- RNF39 5
- ENSG00000239920 5
(6) SIMAP similar genes for TRIM65 Gene using alignment to 7 proteins:
- TRI65_HUMAN
- H0YG27_HUMAN
- H0YGS7_HUMAN
- K7EJ59_HUMAN
- K7EM44_HUMAN
- L8E9Q5_HUMAN
- Q96DX1_HUMAN
Variants for TRIM65 Gene
| SNP ID | Clin | Chr 17 pos | Variation | AA Info | Type |
|---|---|---|---|---|---|
| rs1000162227 | -- | 75,898,241(-) | C/T | upstream_transcript_variant | |
| rs1000178036 | -- | 75,894,148(-) | C/A | intron_variant | |
| rs1000236073 | -- | 75,898,003(-) | T/C | upstream_transcript_variant | |
| rs1000545846 | -- | 75,880,014(-) | AAA/AAAAAA | downstream_transcript_variant | |
| rs1000574119 | -- | 75,896,818(-) | C/T | coding_sequence_variant, non_coding_transcript_variant, stop_gained |
Gene Damage Index Score:
8.02;
84.22% of all genes are more intolerant (likely to be disease-causing)
Additional Variant Information for TRIM65 Gene
- SNPedia medical, phenotypic, and genealogical associations of SNPs for
- TRIM65
SNP Genotyping and Copy Number Assay Products
No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for TRIM65 Gene
Disorders for TRIM65 Gene
Additional Disease Information for TRIM65
- Genetic Association Database
- (GAD)
- ATLAS of Genetics and Cytogenetics in Oncology and Haematology
No disorders were found for TRIM65 Gene.
No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for TRIM65 Gene
Publications for TRIM65 Gene
- TRIM65 negatively regulates p53 through ubiquitination. (PMID: 27012201) Li Y … Yu Z (Biochemical and biophysical research communications 2016) 2 3 56
- TRIM65 regulates microRNA activity by ubiquitination of TNRC6. (PMID: 24778252) Li S … Dorf ME (Proceedings of the National Academy of Sciences of the United States of America 2014) 2 3 56
- Genome-wide association studies of cerebral white matter lesion burden: the CHARGE consortium. (PMID: 21681796) Fornage M … Launer LJ (Annals of neurology 2011) 3 43 56
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard DS … MGC Project Team (Genome research 2004) 3 4 56
- Activity-based E3 ligase profiling uncovers an E3 ligase with esterification activity. (PMID: 29643511) Pao KC … Virdee S (Nature 2018) 3 56
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Products for TRIM65 Gene
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Sources for TRIM65 Gene
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