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TRIM64 Gene(Protein Coding)

Tripartite Motif Containing 64

GCID:
GC11P089968
GIFtS:
26
Genes Participants
UDN Logo

Aliases for TRIM64 Gene

Aliases for TRIM64 Gene

  • Tripartite Motif Containing 64 2 3 5
  • C11orf28 3 4
  • Tripartite Motif-Containing Protein 64 3
  • Chromosome 11 Open Reading Frame 28 2
  • Tripartite Motif-Containing 64 2
  • TRIM64A 3

External Ids for TRIM64 Gene

Previous HGNC Symbols for TRIM64 Gene

  • C11orf28

Previous GeneCards Identifiers for TRIM64 Gene

  • GC11P089336
  • GC11P089701
  • GC11M085791

Summaries for TRIM64 Gene

GeneCards Summary for TRIM64 Gene

TRIM64 (Tripartite Motif Containing 64) is a Protein Coding gene. An important paralog of this gene is TRIM64B.

Additional gene information for TRIM64 Gene

No data available for Entrez Gene Summary , CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for TRIM64 Gene

Genomics for TRIM64 Gene

Products:

  1. Regulatory Element

GeneHancer (GH) Regulatory Elements for TRIM64 Gene


Top Transcription factor binding sites by QIAGEN in the TRIM64 gene promoter:

Genomic Locations for TRIM64 Gene

Genomic Locations for TRIM64 Gene
chr11:89,966,087-89,975,228
(GRCh38/hg38)
Size:
9,142 bases
Orientation:
Plus strand
chr11:89,701,672-89,708,396
(GRCh37/hg19)

Genomic View for TRIM64 Gene

Genes around TRIM64 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
TRIM64 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for TRIM64 Gene
GeneLoc Logo Genomic Neighborhood • Exon Structure • Gene Density

RefSeq DNA sequence for TRIM64 Gene

Proteins for TRIM64 Gene

Products:

  1. Antibody
  2. Protein
  3. Assay

  • Protein details for TRIM64 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    A6NGJ6-TRI64_HUMAN
    Recommended name:
    Tripartite motif-containing protein 64
    Protein Accession:
    A6NGJ6

    Protein attributes for TRIM64 Gene

    Size:
    449 amino acids
    Molecular mass:
    51566 Da
    Quaternary structure:
    No Data Available

neXtProt entry for TRIM64 Gene

Post-translational modifications for TRIM64 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for TRIM64 Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for TRIM64 Gene

Domains & Families for TRIM64 Gene

Gene Families for TRIM64 Gene

HGNC:
Human Protein Atlas (HPA):
  • Predicted intracellular proteins

Protein Domains for TRIM64 Gene

InterPro:
ProtoNet:

Suggested Antigen Peptide Sequences for TRIM64 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

A6NGJ6

UniProtKB/Swiss-Prot:

TRI64_HUMAN :
  • Belongs to the TRIM/RBCC family.
Family:
  • Belongs to the TRIM/RBCC family.
genes like me logo Genes that share domains with TRIM64: view

Function for TRIM64 Gene

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  1. Animal Model
  2. CRISPR
  3. miRNA
  4. Inhibitory RNA
  5. Clone
  6. Cell Line

Gene Ontology (GO) - Molecular Function for TRIM64 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0008270 zinc ion binding IEA --
GO:0046872 metal ion binding IEA --
genes like me logo Genes that share ontologies with TRIM64: view
genes like me logo Genes that share phenotypes with TRIM64: view

Animal Model Products

Clone Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes From GWAS Catalog , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for TRIM64 Gene

Localization for TRIM64 Gene

Gene Ontology (GO) - Cellular Components for TRIM64 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005622 intracellular IEA --
genes like me logo Genes that share ontologies with TRIM64: view

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Subcellular locations from the Human Protein Atlas (HPA) for TRIM64 Gene

Pathways & Interactions for TRIM64 Gene

SuperPathways for TRIM64 Gene

PathCards logo More details on SuperPathways for TRIM64
No Data Available

Interacting Proteins for TRIM64 Gene

Gene Ontology (GO) - Biological Process for TRIM64 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for TRIM64 Gene

Drugs & Compounds for TRIM64 Gene

Products:

  1. Drug
No Compound Related Data Available

Transcripts for TRIM64 Gene

Products:

  1. CRISPR
  2. miRNA
  3. Inhibitory RNA
  4. Clone

mRNA/cDNA for TRIM64 Gene

(2) REFSEQ mRNAs :
(0) Additional mRNA sequences :
-
(5) Selected AceView cDNA sequences:
(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for TRIM64 Gene

Tripartite motif containing 64:
Representative Sequences:

Clone Products

Alternative Splicing Database (ASD) splice patterns (SP) for TRIM64 Gene

No ASD Table

Relevant External Links for TRIM64 Gene

GeneLoc Exon Structure for
TRIM64
ECgene alternative splicing isoforms for
TRIM64

Expression for TRIM64 Gene

Products:

  1. Primer
  2. Gene Expression Assay

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for TRIM64 Gene

mRNA expression in normal human tissues for TRIM64 Gene
mRNA expression by GTEx for TRIM64 Gene

NURSA nuclear receptor signaling pathways regulating expression of TRIM64 Gene:

TRIM64

SOURCE GeneReport for Unigene cluster for TRIM64 Gene:

Hs.454490
genes like me logo Genes that share expression patterns with TRIM64: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for TRIM64 Gene

Orthologs for TRIM64 Gene

This gene was present in the common ancestor of human and chimp.

Orthologs for TRIM64 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
 Mammalia TRIM64B 33
  • 98.29 (n)
Species where no ortholog for TRIM64 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • cow (Bos Taurus)
  • dog (Canis familiaris)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • mouse (Mus musculus)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for TRIM64 Gene

ENSEMBL:
Gene Tree for TRIM64 (if available)
TreeFam:
Gene Tree for TRIM64 (if available)

Paralogs for TRIM64 Gene

Paralogs for TRIM64 Gene

(24) SIMAP similar genes for TRIM64 Gene using alignment to 1 proteins:

Pseudogenes.org Pseudogenes for TRIM64 Gene

genes like me logo Genes that share paralogs with TRIM64: view

Variants for TRIM64 Gene

Products:

  1. SNP Genotyping and Copy Number Assay

Sequence variations from dbSNP and Humsavar for TRIM64 Gene

SNP ID Clin Chr 11 pos Variation AA Info Type
rs1002841791 -- 89,964,573(+) A/G upstream_transcript_variant
rs1008040946 -- 89,972,737(+) A/G intron_variant
rs1008407596 -- 89,968,540(+) C/G coding_sequence_variant, missense_variant
rs1012183015 -- 89,965,113(+) T/C upstream_transcript_variant
rs1016888332 -- 89,965,204(+) A/G upstream_transcript_variant

Structural Variations from Database of Genomic Variants (DGV) for TRIM64 Gene

Variant ID Type Subtype PubMed ID
esv2759849 CNV gain+loss 17122850
esv3579832 CNV loss 25503493
esv3579993 CNV gain 25503493
esv3892056 CNV gain+loss 25118596
esv3892060 CNV gain 25118596
nsv1036092 CNV loss 25217958
nsv1070473 CNV deletion 25765185
nsv1133000 OTHER inversion 24896259
nsv1136137 CNV deletion 24896259
nsv469862 CNV gain 16826518
nsv508646 CNV deletion 20534489
nsv7222 OTHER inversion 18451855
nsv819015 CNV loss 19587683
nsv832225 CNV gain 17160897
nsv8858 CNV gain+loss 18304495
nsv972060 CNV duplication 23825009

Additional Variant Information for TRIM64 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
TRIM64

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for TRIM64 Gene

Disorders for TRIM64 Gene

Additional Disease Information for TRIM64

ATLAS of Genetics and Cytogenetics in Oncology and Haematology

No disorders were found for TRIM64 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for TRIM64 Gene

Publications for TRIM64 Gene

  1. Human chromosome 11 DNA sequence and analysis including novel gene identification. (PMID: 16554811) Taylor TD … Sakaki Y (Nature 2006) 3 4 58
  2. Identification of a genomic reservoir for new TRIM genes in primate genomes. (PMID: 22144910) Han K … Sawyer SL (PLoS genetics 2011) 3 58

Products for TRIM64 Gene

Sources for TRIM64 Gene

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