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Aliases for TRIM64 Gene
Aliases for TRIM64 Gene
External Ids for TRIM64 Gene
- HGNC: 14663
- Entrez Gene: 120146
- Ensembl: ENSG00000204450
- UniProtKB: A6NGJ6
Previous HGNC Symbols for TRIM64 Gene
- C11orf28
Previous GeneCards Identifiers for TRIM64 Gene
- GC11P089336
- GC11P089701
- GC11M085791
Summaries for TRIM64 Gene
GeneCards Summary for TRIM64 Gene
TRIM64 (Tripartite Motif Containing 64) is a Protein Coding gene. Diseases associated with TRIM64 include Septooptic Dysplasia. An important paralog of this gene is TRIM64B.
Additional gene information for TRIM64 Gene
No data available for Entrez Gene Summary , CIViC Summary , UniProtKB/Swiss-Prot Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , Rfam classification and piRNA Summary for TRIM64 Gene
Genomics for TRIM64 Gene
GeneHancer (GH) Regulatory Elements Pubs
Cistromic (ChIP-Seq) regulation report from SPP (The Signaling Pathways Project) for TRIM64
- Top Transcription factor binding sites by QIAGEN in the TRIM64 gene promoter:
-
- aMEF-2
- Brachyury
- C/EBPalpha
- C/EBPbeta
- CUTL1
- E4BP4
- Evi-1
- Gfi-1
- HFH-1
- MEF-2A
Genomic Locations for TRIM64 Gene
Genomic Locations for TRIM64 Gene
- chr11:89,966,068-89,974,147
- (GRCh38/hg38)
- Size:
- 8,080 bases
- Orientation:
- Plus strand
- chr11:89,701,672-89,708,396
- (GRCh37/hg19)
- Size:
- 6,725 bases
- Orientation:
- Plus strand
Genomic View for TRIM64 Gene
Genes around TRIM64 on UCSC Golden Path with GeneCards custom track
- Cytogenetic band:
-
- 11q14.3 by HGNC
- 11q14.3 by Entrez Gene
- 11q14.3 by Ensembl
TRIM64 Gene in genomic location: bands according to
Ensembl, locations according to GeneLoc
(and/or Entrez Gene and/or Ensembl if different)
Genomic Neighborhood
• Exon Structure
• Gene Density
RefSeq DNA sequence for TRIM64 Gene
Proteins for TRIM64 Gene
-
Protein details for TRIM64 Gene (UniProtKB/Swiss-Prot)
- Protein Symbol:
- A6NGJ6-TRI64_HUMAN
- Recommended name:
- Tripartite motif-containing protein 64
- Protein Accession:
- A6NGJ6
Protein attributes for TRIM64 Gene
- Size:
- 449 amino acids
- Molecular mass:
- 51566 Da
- Quaternary structure:
- No Data Available
Post-translational modifications for TRIM64 Gene
Other Protein References for TRIM64 Gene
- ENSEMBL proteins:
- REFSEQ proteins:
Antibody Products
- Creative Diagnostics Anti-TRIM64 (aa 345-374) polyclonal antibody
-
Custom Antibody ServicesOriGene Antibodies for TRIM64
- Novus Biologicals Antibodies for TRIM64
- Invitrogen Antibodies for TRIM64 (AFLGC-TRIM64)
- antibodies-online: Show 9 available TRIM64 Antibodies ranked by validation data
Protein Products
- Search Origene for Purified Proteins, MassSpec and Protein Over-expression Lysates for TRIM64
- Origene Custom Protein Services for TRIM64
- Novus Biologicals proteins for TRIM64
No data available for DME Specific Peptides for TRIM64 Gene
Domains & Families for TRIM64 Gene
Gene Families for TRIM64 Gene
- HGNC:
- Human Protein Atlas (HPA):
-
- Predicted intracellular proteins
Protein Domains for TRIM64 Gene
Suggested Antigen Peptide Sequences for TRIM64 Gene
- GenScript: Design optimal peptide antigens:
-
- Tripartite motif-containing protein 64 (TRI64_HUMAN)
Graphical View of Domain Structure for InterPro Entry
A6NGJ6- Family:
-
- Belongs to the TRIM/RBCC family.
Function for TRIM64 Gene
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0005515 | protein binding | IEA | -- |
| GO:0008270 | zinc ion binding | IEA | -- |
| GO:0046872 | metal ion binding | IEA | -- |
| GO:0061630 | ubiquitin protein ligase activity | IBA | 21873635 |
Phenotypes for TRIM64 Gene
Animal Model Products
- Taconic Biosciences: Generate A Custom CRISPR Mouse Model For Your Study
CRISPR Products
- Applied Biological Materials (abm): CRISPR Clones for TRIM64 - Select products 50% OFF >
- * TRIM64 CRISPR as ready-to-use vector or virus: ORF | Lenti- | Adeno- | AAV- | Protein Vector - Browse All
- * Gene synthesis, site-directed mutagenesis, subcloning, and more services - Browse All
-
OriGene CRISPR knockouts for TRIM64
- Search GeneCopoeia for CRISPR/Cas9 clones, lentivirus and AAV products for TRIM64
-
Santa Cruz Biotechnology (SCBT) CRISPR for TRIM64
miRNA Products
Inhibitory RNA Products
- Origene shrna, sirna, and RNAi products in human, mouse, rat for TRIM64
- Browse OriGene Inhibitory RNA Products For TRIM64
- Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for TRIM64
Clone Products
- Applied Biological Materials (abm): Clones for TRIM64 - Select products 50% OFF >
- * TRIM64 as ready-to-use vector or virus: ORF | Lenti- | Retro- | Adeno- | AAV- | Protein Vector - Browse All
- * Gene synthesis, site-directed mutagenesis, subcloning, and more services - Browse All
- Sino Biological Human cDNA Clone for TRIM64
- Search GeneCopoeia for ORF cDNA, lentivirus, AAV viral particles and/or promoter clone products for TRIM64
Cell Line Products
-
Horizon Cell Lines for TRIM64
No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes From GWAS Catalog , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for TRIM64 Gene
Localization for TRIM64 Gene
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0005737 | cytoplasm | IBA | 21873635 |
No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Subcellular locations from the Human Protein Atlas (HPA) for TRIM64 Gene
Pathways & Interactions for TRIM64 Gene
Interacting Proteins for TRIM64 Gene
GPS-Prot Interaction Network for TRIM64
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0010468 | regulation of gene expression | IBA | 21873635 |
| GO:0016567 | protein ubiquitination | IBA | 21873635 |
| GO:0045087 | innate immune response | IBA | 21873635 |
No data available for Pathways by source and SIGNOR curated interactions for TRIM64 Gene
Transcripts for TRIM64 Gene
mRNA/cDNA for TRIM64 Gene
- 1 REFSEQ mRNAs :
- 1 Ensembl transcripts including schematic representations, and UCSC links to gene/alias where relevant :
-
- ENST00000533122 1535 nts (view in UCSC)
CRISPR Products
- Applied Biological Materials (abm): CRISPR Clones for TRIM64 - Select products 50% OFF >
- * TRIM64 CRISPR as ready-to-use vector or virus: ORF | Lenti- | Adeno- | AAV- | Protein Vector - Browse All
- * Gene synthesis, site-directed mutagenesis, subcloning, and more services - Browse All
-
OriGene CRISPR knockouts for TRIM64
- Search GeneCopoeia for CRISPR/Cas9 clones, lentivirus and AAV products for TRIM64
-
Santa Cruz Biotechnology (SCBT) CRISPR for TRIM64
miRNA Products
Inhibitory RNA Products
- Origene shrna, sirna, and RNAi products in human, mouse, rat for TRIM64
- Browse OriGene Inhibitory RNA Products For TRIM64
- Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for TRIM64
Clone Products
- Applied Biological Materials (abm): Clones for TRIM64 - Select products 50% OFF >
- * TRIM64 as ready-to-use vector or virus: ORF | Lenti- | Retro- | Adeno- | AAV- | Protein Vector - Browse All
- * Gene synthesis, site-directed mutagenesis, subcloning, and more services - Browse All
- Sino Biological Human cDNA Clone for TRIM64
- Search GeneCopoeia for ORF cDNA, lentivirus, AAV viral particles and/or promoter clone products for TRIM64
Relevant External Links for TRIM64 Gene
- GeneLoc Exon Structure for
- TRIM64
Expression for TRIM64 Gene
Transcriptomic regulation report from SPP (The Signaling Pathways Project) for TRIM64
SOURCE GeneReport for Unigene cluster for TRIM64 Gene:
Hs.454490Primer Products
Gene Expression Assay Products
No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for TRIM64 Gene
Orthologs for TRIM64 Gene
This gene was present in the common ancestor of human and chimp.
| Organism | Taxonomy | Gene | Similarity | Type | Details |
|---|---|---|---|---|---|
| Chimpanzee (Pan troglodytes) |
Mammalia | TRIM64B 30 |
|
- Species where no ortholog for TRIM64 was found in the sources mined by GeneCards:
-
- A. gosspyii yeast (Eremothecium gossypii)
- Actinobacteria (Mycobacterium tuberculosis)
- African clawed frog (Xenopus laevis)
- African malaria mosquito (Anopheles gambiae)
- Alicante grape (Vitis vinifera)
- Alpha proteobacteria (Wolbachia pipientis)
- Amoeba (Dictyostelium discoideum)
- Archea (Pyrococcus horikoshii)
- Baker's yeast (Saccharomyces cerevisiae)
- Barley (Hordeum vulgare)
- Beta proteobacteria (Neisseria meningitidis)
- Bread mold (Neurospora crassa)
- Chicken (Gallus gallus)
- Chromalveolata (Phytophthora infestans)
- Common water flea (Daphnia pulex)
- Corn (Zea mays)
- Cow (Bos Taurus)
- Dog (Canis familiaris)
- E. coli (Escherichia coli)
- Filamentous fungi (Aspergillus nidulans)
- Firmicute Bacteria (Streptococcus pneumoniae)
- Fission Yeast (Schizosaccharomyces pombe)
- Fruit Fly (Drosophila melanogaster)
- Green Algae (Chlamydomonas reinhardtii)
- Honey Bee (Apis mellifera)
- K. Lactis Yeast (Kluyveromyces lactis)
- Lizard (Anolis carolinensis)
- Loblloly Pine (Pinus taeda)
- Malaria Parasite (Plasmodium falciparum)
- Medicago Trunc (Medicago Truncatula)
- Moss (Physcomitrella patens)
- Mouse (Mus musculus)
- Oppossum (Monodelphis domestica)
- Orangutan (Pongo pygmaeus)
- Pig (Sus scrofa)
- Platypus (Ornithorhynchus anatinus)
- Rainbow Trout (Oncorhynchus mykiss)
- Rat (Rattus norvegicus)
- Rice (Oryza sativa)
- Rice Blast Fungus (Magnaporthe grisea)
- Schistosome Parasite (Schistosoma mansoni)
- Sea Anemone (Nematostella vectensis)
- Sea Vase (Ciona intestinalis)
- Sea Squirt (Ciona savignyi)
- Sea Urchin (Strongylocentrotus purpuratus)
- Sorghum (Sorghum bicolor)
- Soybean (Glycine max)
- Stem Rust Fungus (Puccinia graminis)
- Sugarcane (Saccharum officinarum)
- Thale Cress (Arabidopsis thaliana)
- Tomato (Lycopersicon esculentum)
- Toxoplasmosis (Toxoplasma gondii)
- Trichoplax (Trichoplax adhaerens)
- Tropical Clawed Frog (Silurana tropicalis)
- Wheat (Triticum aestivum)
- Worm (Caenorhabditis elegans)
- Zebrafish (Danio rerio)
Paralogs for TRIM64 Gene
Paralogs for TRIM64 Gene
- TRIM64B 5
- TRIM64C 5
- TRIM68 5
- TRIM11 5
- TRIM49B 5
- TRIM51 5
- TRIM4 5
- TRIM43B 5
- TRIM43 5
- TRIM49 5
- TRIM49C 5
- TRIM51GP 5
- TRIM21 5
- TRIM7 5
- TRIM41 5
- TRIM17 5
- TRIM77 5
- TRIM49D1 5
- TRIM49D2 5
- TRIM34 5
- TRIM60 5
- TRIM6-TRIM34 5
- TRIM58 5
- TRIM22 5
- TRIM6 5
- TRIM5 5
- TRIM15 5
- TRIM26 5
- TRIM27 5
- TRIM75P 5
- TRIM10 5
- TRIM50 5
- TRIM72 5
- MEFV 5
- TRIM39 5
- TRIM62 5
- TRIM38 5
- TRIML1 5
- MID2 5
- MID1 5
- TRIM25 5
- TRIM71 5
- TRIM2 5
- TRIM32 5
- TRIM69 5
- TRIM47 5
- TRIM67 5
- TRIM3 5
- TRIM9 5
- TRIM39-RPP21 5
- TRIM33 5
- TRIM56 5
- RNF39 5
- TRIM65 5
- TRIM35 5
- TRIM14 5
- TRIML2 5
- TRIM24 5
- TRIM31 5
- TRIM42 5
- TRIM16 5
- TRIM48 5
- TRIM28 5
- TRIM13 5
- TRIM46 5
- TRIM54 5
- TRIM73 5
- TRIM40 5
- TRIM55 5
- TRIM8 5
- TRIM37 5
- TRIM52 5
- TRIM66 5
- TRIM29 5
- TRIM74 5
- TRIM36 5
- PML 5
- TRIM45 5
- TRIM61 5
- TRIM63 5
- TRIM16L 5
- BSPRY 5
- TRIM44 5
- ENSG00000239920 5
- TRIM64B 30
(24) SIMAP similar genes for TRIM64 Gene using alignment to 1 proteins:
- TRI64_HUMAN
Pseudogenes.org Pseudogenes for TRIM64 Gene
Variants for TRIM64 Gene
| Variant ID | Type | Subtype | PubMed ID |
|---|---|---|---|
| esv2759849 | CNV | gain+loss | 17122850 |
| esv3579832 | CNV | loss | 25503493 |
| esv3579993 | CNV | gain | 25503493 |
| esv3892056 | CNV | gain+loss | 25118596 |
| esv3892060 | CNV | gain | 25118596 |
| nsv1036092 | CNV | loss | 25217958 |
| nsv1070473 | CNV | deletion | 25765185 |
| nsv1133000 | OTHER | inversion | 24896259 |
| nsv1136137 | CNV | deletion | 24896259 |
| nsv469862 | CNV | gain | 16826518 |
| nsv508646 | CNV | deletion | 20534489 |
| nsv7222 | OTHER | inversion | 18451855 |
| nsv819015 | CNV | loss | 19587683 |
| nsv832225 | CNV | gain | 17160897 |
| nsv8858 | CNV | gain+loss | 18304495 |
| nsv972060 | CNV | duplication | 23825009 |
Additional Variant Information for TRIM64 Gene
- SNPedia medical, phenotypic, and genealogical associations of SNPs for
- TRIM64
SNP Genotyping and Copy Number Assay Products
No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Sequence variations, with clinical significance, from ClinVar and Humsavar, with links to dbSNP and Variation tolerance for TRIM64 Gene
Disorders for TRIM64 Gene
| Disorder | Aliases | PubMed IDs |
|---|---|---|
| septooptic dysplasia |
|
|
Search TRIM64 in MalaCards
View complete list of genes associated with diseases
Additional Disease Information for TRIM64
No data available for UniProtKB/Swiss-Prot and Genatlas for TRIM64 Gene
Publications for TRIM64 Gene
- Human chromosome 11 DNA sequence and analysis including novel gene identification. (PMID: 16554811) Taylor TD … Sakaki Y (Nature 2006) 3 4
- Identification of a genomic reservoir for new TRIM genes in primate genomes. (PMID: 22144910) Han K … Sawyer SL (PLoS genetics 2011) 3
- Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. (PMID: 21873635) Gaudet P … Thomas PD (Briefings in bioinformatics 2011) 3
ExternalLinks
Products for TRIM64 Gene
- Custom Antibody ServicesOriGene Antibodies for TRIM64
- Browse OriGene ELISA Kits
- Custom Assay Services
- Search Origene for Purified Proteins, MassSpec and Protein Over-expression Lysates for TRIM64
- Origene Custom Protein Services for TRIM64
- Origene shrna, sirna, and RNAi products in human, mouse, rat for TRIM64
- Browse OriGene Inhibitory RNA Products For TRIM64
- Browse OriGene qPCR primer pairs and template standards
- OriGene CRISPR knockouts for TRIM64
- OriGene ORF clones in human for TRIM64
- Custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
- Browse OriGene miRNA Products For TRIM64
- Sino Biological Human cDNA Clone for TRIM64
- Browse Sino Biological Recombinant Proteins
- Browse Sino Biological Cell Lysates
- Browse Sino Biological Antibodies
- Browse Sino Biological Assays
- Browse cDNA Clones
- Browse ELISA Kits
- Browse CRO Services
- High-throughput Antibody Production Service
- Protein Production Service
- Epitope Tag Antibodies & Reporter Protein Antibodies
- Lentiviral ORF Clones
- Novus Biologicals Antibodies for TRIM64
- Novus Biologicals proteins for TRIM64
- Browse Antibodies
- Browse Peptides and Proteins
- Browse Lysates
- Browse ELISA Kits
- Invitrogen Antibodies for TRIM64 (AFLGC-TRIM64)
- VectorBuilder Custom and pre-made DNA vectors for TRIM64 (ie. gene expression, shRNA knockdown, CRISPR)
- VectorBuilder Viral vectors for TRIM64 (ie. lentivirus, AAV, adenovirus)
- VectorBuilder CRISPR vectors for TRIM64 (ie. knockout, knockin, CRISPRa, CRISPRi)
- VectorBuilder Virus packaging for TRIM64 CRISPR vectors (ie. lentivirus, AAV, adenovirus)
- VectorBuilder Stable cell line generation for TRIM64
- antibodies-online: Show 9 available TRIM64 Antibodies ranked by validation data
- antibodies-online: Search results for available TRIM64 related products ranked by validation data
- antibodies-online: Search results for available TRIM64 related products ranked by validation data
- Horizon Cell Lines for TRIM64
- Browse GeneCopoeia Cell Lines
- Search GeneCopoeia for CRISPR/Cas9 clones, lentivirus and AAV products for TRIM64
- Search GeneCopoeia for ORF cDNA, lentivirus, AAV viral particles and/or promoter clone products for TRIM64
- Search GeneCopoeia for miRNA 3'UTR Target clone products for TRIM64
- Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for TRIM64
Sources for TRIM64 Gene
- (1) GeneCards
- (2) HGNC
- (3) NCBI Entrez Gene
- (4) UniProtKB/Swiss-Prot
- (5) Ensembl
- (6) OMIM
- (7) GeneLoc
- (8) Gene Wiki
- (9) UCSC
- (10) PhosphoSitePlus
- (11) Cell Signaling Technology
- (12) GO
- (13) UniProtKB/TrEMBL
- (14) InterPro
- (15) ProtoNet
- (16) Blocks
- (17) MGI
- (18) IUBMB
- (19) KEGG
- (20) MINT
- (21) STRING
- (22) IntAct
- (23) Novoseek
- (24) PharmGKB
- (25) DrugBank
- (26) HMDB
- (27) ASD
- (28) SAGE
- (29) SOURCE
- (30) HomoloGene
- (31) PanEnsembl
- (32) euGenes
- (33) SGD
- (34) FlyBase
- (35) WormBase
- (36) Pseudogene
- (37) DGV
- (38) dbSNP
- (39) GenAtlas
- (40) HGMD
- (41) GAD
- (42) BGMUT
- (43) HuGE
- (44) Atlas
- (45) GenBank
- (46) HORDE
- (47) HUGE
- (48) IMGT
- (49) Leiden
- (50) miRBase
- (51) DME
- (52) OriGene
- (53) PubMed
- (54) R&D Systems
- (55) TGDB
- (56) Tocris
- (57) Abcam
- (58) Novus Biologicals
- (59) ProSpec
- (60) Sino Biological
- (61) GenScript
- (62) Qiagen
- (63) OCA
- (64) Proteopedia
- (65) MOPED
- (66) neXtProt
- (67) Reactome
- (68) GeneGo (Thomson Reuters)
- (69) DISEASES
- (70) SIMAP
- (71) GenomeRNAi
- (72) LifeMap
- (73) miRTarBase
- (74) MalaCards
- (75) Invitrogen
- (76) BitterDB
- (77) ESI-BIO
- (78) RefSeq
- (79) BioSystems
- (80) MaxQB
- (81) IUPHAR
- (82) BioGPS
- (83) Illumina
- (84) COMPARTMENTS
- (85) HOMER
- (86) PaxDb
- (87) ApexBio
- (88) Addgene
- (89) antibodies-online
- (90) CYP
- (91) NONCODE
- (92) TreeFam
- (93) PathCards
- (94) GeneReviews
- (95) GeneTex
- (96) Taconic Biosciences
- (97) GTEx
- (98) ProteomicsDB
- (99) SCBT
- (100) DGIdb
- (101) ClinicalTrials
- (102) RVIS
- (103) SIGNOR
- (104) diseasecard
- (105) NIH Rare Diseases
- (106) Orphanet
- (107) UMLS
- (108) GTR
- (109) Disease Ontology
- (110) Genetics Home Reference
- (111) MeSH
- (112) MedlinePlus
- (113) CDC
- (114) NINDS
- (115) NCBI Bookshelf
- (116) ClinVar
- (117) Gene Damage Index
- (118) HPO
- (119) UDN
- (120) VISTA
- (121) FANTOM5
- (122) ENCODE
- (123) ProSci
- (124) Horizon
- (125) The Signaling Pathways Project (SPP)
- (126) IID
- (127) VectorBuilder
- (128) SNPedia
- (129) BRCA Exchange
- (130) CIViC
- (131) ProteoGenix
- (132) dbSUPER
- (133) TISSUES
- (134) Gene ORGANizer
- (135) abm
- (136) Human Protein Atlas
- (137) GWAS Catalog
- (138) Monarch Initiative
- (139) DataMed
- (140) HumanCyc
- (141) UCNEbase
- (142) EPDnew
- (143) Applied Biosystems
- (144) GlyConnect
- (145) Aminode
- (146) GeneCopoeia
- (147) GPS-Prot
- (148) RNACentral
- (149) LncRNADisease
- (150) LOVD
- (151) miR2Disease
- (152) DiseaseEnhancer
- (153) Boster Bio
- (154) Biorbyt
- (155) Biocompare
- (156) Mastermind
- (157) CTD^2 Dashboard
- (158) CraniofacialAtlas
- (159) GeneImprint
- (160) Synthego
- (161) ENA
- (162) GtRNAdb
- (163) LncBase
- (164) LncBook
- (165) LNCipedia
- (166) Modomics
- (167) PDBe
- (168) Rfam
- (169) SILVA
- (170) snOPY
- (171) SRPDB
- (172) GENCODE
- (173) TarBase
- (174) Signalway Antibody
- (175) Open Targets Platform
- (176) 5SRRNADB
- (177) snoDB
- (178) MirGeneDB