Aliases for TRIM58 Gene
External Ids for TRIM58 Gene
Previous GeneCards Identifiers for TRIM58 Gene
GeneCards Summary for TRIM58 Gene
TRIM58 (Tripartite Motif Containing 58) is a Protein Coding gene. Diseases associated with TRIM58 include Lung Squamous Cell Carcinoma. Gene Ontology (GO) annotations related to this gene include ligase activity. An important paralog of this gene is TRIM21.
UniProtKB/Swiss-Prot Summary for TRIM58 Gene
E3 ubiquitin ligase induced during late erythropoiesis. Directly binds and ubiquitinates the intermediate chain of the microtubule motor dynein (DYNC1LI1/DYNC1LI2), stimulating the degradation of the dynein holoprotein complex. May participate in the erythroblast enucleation process through regulation of nuclear polarization.