Aliases for TRIM54 Gene
External Ids for TRIM54 Gene
Previous HGNC Symbols for TRIM54 Gene
Previous GeneCards Identifiers for TRIM54 Gene
The protein encoded by this gene contains a RING finger motif and is highly similar to the ring finger proteins RNF28/MURF1 and RNF29/MURF2. In vitro studies demonstrated that this protein, RNF28, and RNF29 form heterodimers, which may be important for the regulation of titin kinase and microtubule-dependent signal pathways in striated muscles. Alternatively spliced transcript variants encoding distinct isoforms have been reported. [provided by RefSeq, Jul 2008]
GeneCards Summary for TRIM54 Gene
TRIM54 (Tripartite Motif Containing 54) is a Protein Coding gene. Diseases associated with TRIM54 include Cylindrical Spirals Myopathy and Hyaline Body Myopathy. Gene Ontology (GO) annotations related to this gene include obsolete signal transducer activity and microtubule binding. An important paralog of this gene is TRIM55.
UniProtKB/Swiss-Prot Summary for TRIM54 Gene
May bind and stabilize microtubules during myotubes formation.