Aliases for TRIM47 Gene
Aliases for TRIM47 Gene
External Ids for TRIM47 Gene
- HGNC: 19020
- Entrez Gene: 91107
- Ensembl: ENSG00000132481
- OMIM: 611041
- UniProtKB: Q96LD4
Previous GeneCards Identifiers for TRIM47 Gene
- GC17M076896
- GC17M074334
- GC17M074468
- GC17M074469
- GC17M071381
- GC17M073870
- GC17M069295
Summaries for TRIM47 Gene
GeneCards Summary for TRIM47 Gene
TRIM47 (Tripartite Motif Containing 47) is a Protein Coding gene. Diseases associated with TRIM47 include Astrocytoma. An important paralog of this gene is TRIM25.
Additional gene information for TRIM47 Gene
No data available for Entrez Gene Summary , CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for TRIM47 Gene
Genomics for TRIM47 Gene
GeneHancer (GH) Regulatory Elements for TRIM47 Gene
Promoters and enhancers for TRIM47 Gene
- Elite GeneHancer and/or Elite GeneHancer-gene association
Download GeneHancer data dump
GeneHancers around TRIM47 on UCSC Golden Path with GeneCards custom track
Regulatory Element Products
Genomic Locations for TRIM47 Gene
Genomic Locations for TRIM47 Gene
- chr17:75,874,161-75,878,600
- (GRCh38/hg38)
- Size:
- 4,440 bases
- Orientation:
- Minus strand
- chr17:73,870,242-73,874,656
- (GRCh37/hg19)
Genomic View for TRIM47 Gene
Genes around TRIM47 on UCSC Golden Path with GeneCards custom track
- Cytogenetic band:
-
- 17q25.1 by Ensembl
- 17q25.1 by Entrez Gene
- 17q25 by HGNC
TRIM47 Gene in genomic location: bands according to
Ensembl, locations according to GeneLoc
(and/or Entrez Gene and/or Ensembl if different)
Genomic Neighborhood
• Exon Structure
• Gene Density
RefSeq DNA sequence for TRIM47 Gene
Proteins for TRIM47 Gene
-
Protein details for TRIM47 Gene (UniProtKB/Swiss-Prot)
- Protein Symbol:
- Q96LD4-TRI47_HUMAN
- Recommended name:
- Tripartite motif-containing protein 47
- Protein Accession:
- Q96LD4
- Q96AD0
- Q96GU5
- Q9BRN7
Protein attributes for TRIM47 Gene
- Size:
- 638 amino acids
- Molecular mass:
- 69532 Da
- Quaternary structure:
- No Data Available
Protein Expression for TRIM47 Gene
Post-translational modifications for TRIM47 Gene
No Post-translational modifications
Other Protein References for TRIM47 Gene
- ENSEMBL proteins:
- REFSEQ proteins:
Antibody Products
- Novus Biologicals Antibodies for TRIM47
-
Abcam antibodies for TRIM47
- Invitrogen Antibodies for TRIM47
- GeneTex TRIM47 antibody for TRIM47
Protein Products
-
OriGene Purified Proteins for TRIM47
- Search Origene for MassSpec and Protein Over-expression Lysates for TRIM47
- Origene Custom Protein Services for TRIM47
- Search GeneTex for Proteins for TRIM47
-
Abcam proteins for TRIM47
Assay Products
No data available for DME Specific Peptides for TRIM47 Gene
Domains & Families for TRIM47 Gene
Gene Families for TRIM47 Gene
- HGNC:
- Human Protein Atlas (HPA):
-
- Predicted intracellular proteins
Protein Domains for TRIM47 Gene
- InterPro:
- Blocks:
- ProtoNet:
Suggested Antigen Peptide Sequences for TRIM47 Gene
- GenScript: Design optimal peptide antigens:
Graphical View of Domain Structure for InterPro Entry
Q96LD4- Family:
-
- Belongs to the TRIM/RBCC family.
Function for TRIM47 Gene
Phenotypes From GWAS Catalog for TRIM47 Gene
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0008270 | zinc ion binding | IEA | -- |
| GO:0046872 | metal ion binding | IEA | -- |
Phenotypes for TRIM47 Gene
- GenomeRNAi human phenotypes for TRIM47:
Animal Model Products
- Taconic Biosciences: Generate A Custom CRISPR Mouse Model For Your Study
- Cyagen custom Knockout/knockin (KOKI) mouse models for TRIM47
-
-
ViGene Biosciences lentiviral particle packaged cDNA for TRIM47 gene
-
ViGene Biosciences ready-to-package AAV shRNAs for TRIM47 gene
- Search ViGene Biosciences for TRIM47
CRISPR Products
-
OriGene CRISPR knockouts for TRIM47
- genomics-online: gRNA clones - Search results for available TRIM47 gene related products
- Applied Biological Materials CRISPR for TRIM47
-
Vectors and viruses for KO, Activation, Repression, and more
-
Santa Cruz Biotechnology (SCBT) CRISPR for TRIM47
- GenScript: Design CRISPR guide RNA sequences for TRIM47
miRNA for TRIM47 Gene
- miRTarBase miRNAs that target TRIM47
miRNA Products
- Search ViGene Biosciences for TRIM47
Inhibitory RNA Products
- Origene shrna, sirna, and RNAi products in human, mouse, rat for TRIM47
- Browse OriGene Inhibitory RNA Products For TRIM47
- genomics-online: shRNA clones - Search results for available TRIM47 gene related products
-
ViGene Biosciences ready-to-package AAV shRNAs for TRIM47 gene
Clone Products
- Sino Biological Human cDNA Clone for TRIM47
- Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat
- VectorBuilder custom plasmid, inducible vectors for TRIM47
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for TRIM47
-
VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
- genomics-online: cdna clones - Search results for available TRIM47 gene related products
- orf clones - Search results for available TRIM47 gene related products
- Applied Biological Materials Clones for TRIM47
-
Vectors and viruses for ORF, Lenti, Retro, Adenovirus, AAV, and more
Cell Line Products
-
Horizon Cell Lines for TRIM47
-
ViGene Biosciences adenoviral particle packaged cDNA for TRIM47 gene
-
ViGene Biosciences lentiviral particle packaged cDNA for TRIM47 gene
-
ViGene Biosciences ready-to-package AAV shRNAs for TRIM47 gene
No data available for Molecular function , Enzyme Numbers (IUBMB) , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for TRIM47 Gene
Localization for TRIM47 Gene
Subcellular locations from UniProtKB/Swiss-Prot for TRIM47 Gene
- Cytoplasm. Nucleus.
| Compartment | Confidence |
|---|---|
| nucleus | 5 |
| cytosol | 5 |
- Cytosol (3)
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0005634 | nucleus | IEA | -- |
| GO:0005737 | cytoplasm | IEA | -- |
| GO:0005829 | cytosol | IDA | -- |
Pathways & Interactions for TRIM47 Gene
No Data Available
No data available for Pathways by source and SIGNOR curated interactions for TRIM47 Gene
Transcripts for TRIM47 Gene
mRNA/cDNA for TRIM47 Gene
- (3) REFSEQ mRNAs :
- (4) Additional mRNA sequences :
- (148) Selected AceView cDNA sequences:
- (7) Ensembl transcripts including schematic representations, and UCSC links where relevant :
Unigene Clusters for TRIM47 Gene
CRISPR Products
-
OriGene CRISPR knockouts for TRIM47
- genomics-online: gRNA clones - Search results for available TRIM47 gene related products
- Applied Biological Materials CRISPR for TRIM47
-
Vectors and viruses for KO, Activation, Repression, and more
-
Santa Cruz Biotechnology (SCBT) CRISPR for TRIM47
- GenScript: Design CRISPR guide RNA sequences for TRIM47
miRNA Products
- Search ViGene Biosciences for TRIM47
Inhibitory RNA Products
- Origene shrna, sirna, and RNAi products in human, mouse, rat for TRIM47
- Browse OriGene Inhibitory RNA Products For TRIM47
- genomics-online: shRNA clones - Search results for available TRIM47 gene related products
-
ViGene Biosciences ready-to-package AAV shRNAs for TRIM47 gene
Clone Products
- Sino Biological Human cDNA Clone for TRIM47
- Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat
- VectorBuilder custom plasmid, inducible vectors for TRIM47
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for TRIM47
-
VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
- genomics-online: cdna clones - Search results for available TRIM47 gene related products
- orf clones - Search results for available TRIM47 gene related products
- Applied Biological Materials Clones for TRIM47
-
Vectors and viruses for ORF, Lenti, Retro, Adenovirus, AAV, and more
| ExUns: | 1a | · | 1b | · | 1c | ^ | 2 | ^ | 3 | ^ | 4 | ^ | 5a | · | 5b | ^ | 6a | · | 6b |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| SP1: | - | - | |||||||||||||||||
| SP2: | - | ||||||||||||||||||
| SP3: |
Expression for TRIM47 Gene
mRNA expression in embryonic tissues and stem cells from LifeMap Discovery
-
Skeletal Muscle (Muscoskeletal System)
- Mononuclear Myocytes Hyoid Arch Muscles
- Mononuclear Myocytes Mandibular Arch Muscles
- Myoblasts Mandibular Arch Muscles
- Myoblasts Hyoid Arch Muscles
- Bone (Muscoskeletal System)
- Cartilage (Muscoskeletal System)
-
Blood (Hematopoietic System)
- Hematopoietic Stem Cells Hematopoietic Bone Marrow
-
Limb (Muscoskeletal System)
- Mesenchymal Condensate Cells Zeugopod
-
Testis (Reproductive System)
This gene is overexpressed in Breast (25.0).
Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, PaxDb, MaxQB, and MOPED for TRIM47 Gene
- Elite partner
NURSA nuclear receptor signaling pathways regulating expression of TRIM47 Gene:
TRIM47SOURCE GeneReport for Unigene cluster for TRIM47 Gene:
Hs.293660mRNA Expression by UniProt/SwissProt for TRIM47 Gene:
Q96LD4-TRI47_HUMAN
Tissue specificity:
Low expression in most tissues. Higher expression in kidney tubular cells. Overexpressed in astrocytoma tumor cells.
Evidence on tissue expression from TISSUES for TRIM47 Gene
- Lung(4.3)
- Pancreas(4.2)
- Liver(4.1)
- Nervous system(2.5)
Primer Products
-
OriGene qPCR primer pairs for TRIM47
- genomics-online: primer clones - Search results for available TRIM47 gene related products
No data available for mRNA differential expression in normal tissues and Phenotype-based relationships between genes and organs from Gene ORGANizer for TRIM47 Gene
Orthologs for TRIM47 Gene
This gene was present in the common ancestor of chordates.
| Organism | Taxonomy | Gene | Similarity | Type | Details |
|---|---|---|---|---|---|
| chimpanzee (Pan troglodytes) |
Mammalia | TRIM47 33 34 |
|
||
| cow (Bos Taurus) |
Mammalia | TRIM47 33 34 |
|
||
| dog (Canis familiaris) |
Mammalia | TRIM47 33 34 |
|
||
| rat (Rattus norvegicus) |
Mammalia | Trim47 33 |
|
||
| mouse (Mus musculus) |
Mammalia | Trim47 33 16 34 |
|
||
| oppossum (Monodelphis domestica) |
Mammalia | TRIM47 34 |
|
OneToOne | |
| platypus (Ornithorhynchus anatinus) |
Mammalia | TRIM47 34 |
|
OneToOne | |
| chicken (Gallus gallus) |
Aves | TRIM47 33 34 |
|
||
| lizard (Anolis carolinensis) |
Reptilia | TRIM47 34 |
|
OneToOne | |
| zebrafish (Danio rerio) |
Actinopterygii | zgc:153258 34 |
|
ManyToMany |
- Species where no ortholog for TRIM47 was found in the sources mined by GeneCards:
-
- A. gosspyii yeast (Ashbya gossypii)
- Actinobacteria (Mycobacterium tuberculosis)
- African clawed frog (Xenopus laevis)
- African malaria mosquito (Anopheles gambiae)
- Alicante grape (Vitis vinifera)
- alpha proteobacteria (Wolbachia pipientis)
- amoeba (Dictyostelium discoideum)
- Archea (Pyrococcus horikoshii)
- baker's yeast (Saccharomyces cerevisiae)
- barley (Hordeum vulgare)
- beta proteobacteria (Neisseria meningitidis)
- bread mold (Neurospora crassa)
- Chromalveolata (Phytophthora infestans)
- common water flea (Daphnia pulex)
- corn (Zea mays)
- E. coli (Escherichia coli)
- filamentous fungi (Aspergillus nidulans)
- Firmicute bacteria (Streptococcus pneumoniae)
- fission yeast (Schizosaccharomyces pombe)
- fruit fly (Drosophila melanogaster)
- green algae (Chlamydomonas reinhardtii)
- honey bee (Apis mellifera)
- K. lactis yeast (Kluyveromyces lactis)
- loblloly pine (Pinus taeda)
- malaria parasite (Plasmodium falciparum)
- medicago trunc (Medicago Truncatula)
- moss (Physcomitrella patens)
- orangutan (Pongo pygmaeus)
- pig (Sus scrofa)
- rainbow trout (Oncorhynchus mykiss)
- rice (Oryza sativa)
- rice blast fungus (Magnaporthe grisea)
- schistosome parasite (Schistosoma mansoni)
- sea anemone (Nematostella vectensis)
- sea squirt (Ciona intestinalis)
- sea squirt (Ciona savignyi)
- sea urchin (Strongylocentrotus purpuratus)
- sorghum (Sorghum bicolor)
- soybean (Glycine max)
- stem rust fungus (Puccinia graminis)
- sugarcane (Saccharum officinarum)
- thale cress (Arabidopsis thaliana)
- tomato (Lycopersicon esculentum)
- toxoplasmosis (Toxoplasma gondii)
- Trichoplax (Trichoplax adhaerens)
- tropical clawed frog (Silurana tropicalis)
- wheat (Triticum aestivum)
- worm (Caenorhabditis elegans)
Paralogs for TRIM47 Gene
Variants for TRIM47 Gene
| SNP ID | Clin | Chr 17 pos | Variation | AA Info | Type |
|---|---|---|---|---|---|
| rs1000526359 | -- | 75,877,053(-) | ACAGGAGGCCTAGTACAGG/ACAGG | intron_variant | |
| rs1000545846 | -- | 75,880,014(-) | AAA/AAAAAA | upstream_transcript_variant | |
| rs1000649482 | -- | 75,879,584(-) | GTTAAGTTAA/GTTAA | upstream_transcript_variant | |
| rs1000773585 | -- | 75,874,183(-) | T/C | 3_prime_UTR_variant | |
| rs1001227274 | -- | 75,873,988(-) | G/A | downstream_transcript_variant |
Residual Variation Intolerance Score:
43.3% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score:
8.10;
84.52% of all genes are more intolerant (likely to be disease-causing)
Additional Variant Information for TRIM47 Gene
- SNPedia medical, phenotypic, and genealogical associations of SNPs for
- TRIM47
No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for TRIM47 Gene
Disorders for TRIM47 Gene
| Disorder | Aliases | PubMed IDs |
|---|---|---|
| astrocytoma |
|
|
Search TRIM47 in MalaCards
View complete list of genes associated with diseases
Additional Disease Information for TRIM47
- Genetic Association Database
- (GAD)
- ATLAS of Genetics and Cytogenetics in Oncology and Haematology
No data available for UniProtKB/Swiss-Prot and Genatlas for TRIM47 Gene
Publications for TRIM47 Gene
- Genome-wide association studies of cerebral white matter lesion burden: the CHARGE consortium. (PMID: 21681796) Fornage M … Launer LJ (Annals of neurology 2011) 3 44 58
- A probability-based approach for high-throughput protein phosphorylation analysis and site localization. (PMID: 16964243) Beausoleil SA … Gygi SP (Nature biotechnology 2006) 3 4 58
- Global, in vivo, and site-specific phosphorylation dynamics in signaling networks. (PMID: 17081983) Olsen JV … Mann M (Cell 2006) 3 4 58
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard DS … MGC Project Team (Genome research 2004) 3 4 58
- GOA, a novel gene encoding a ring finger B-box coiled-coil protein, is overexpressed in astrocytoma. (PMID: 11511098) Vandeputte DA … Hulsebos TJ (Biochemical and biophysical research communications 2001) 3 4 58
Products for TRIM47 Gene
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- Novus Biologicals
- Novus Biologicals Tissue Microarrays
- Browse Antibodies
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- Abcam antibodies for TRIM47
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- Cloud-Clone Corp. disease models service
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- Cloud-Clone Corp. primary cells service
- Invitrogen Antibodies for TRIM47
- Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat
- Cyagen custom Knockout/knockin (KOKI) mouse models for TRIM47
- VectorBuilder custom plasmid, inducible vectors for TRIM47
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for TRIM47
- VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
- antibodies-online: Search results for available TRIM47 related products ranked by validation data
- antibodies-online: Search results for available TRIM47 related products ranked by validation data
- antibodies-online: Search results for available TRIM47 related products ranked by validation data
- GeneTex TRIM47 antibody for TRIM47
- Search GeneTex for Proteins for TRIM47
- ViGene Biosciences adenoviral particle packaged cDNA for TRIM47 gene
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- Horizon Cell Lines for TRIM47
- genomics-online: cdna clones - Search results for available TRIM47 gene related products
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- genomics-online: primer clones - Search results for available TRIM47 gene related products
- genomics-online: shRNA clones - Search results for available TRIM47 gene related products
Sources for TRIM47 Gene
- (1) GeneCards
- (2) HGNC
- (3) EntrezGene
- (4) Swiss-Prot
- (5) Ensembl
- (6) OMIM
- (7) GeneLoc
- (8) Gene Wiki
- (9) UCSC
- (10) PhosphoSitePlus
- (11) GO
- (12) TrEMBL
- (13) InterPro
- (14) ProtoNet
- (15) Blocks
- (16) MGI
- (17) IUBMB
- (18) KEGG
- (19) MINT
- (20) STRING
- (21) IntAct
- (22) Novoseek
- (23) PharmGKB
- (24) DrugBank
- (25) HMDB
- (26) UniGene
- (27) AceView
- (28) ASD
- (29) ECgene
- (30) GeneAnnot
- (31) CGAP SAGE
- (32) SOURCE
- (33) HomoloGene
- (34) PanEnsembl
- (35) euGenes
- (36) SGD
- (37) FlyBase
- (38) WormBase
- (39) Pseudogene
- (40) DGV
- (41) dbSNP
- (42) GenAtlas
- (43) HGMD
- (44) GAD
- (45) BGMUT
- (46) HuGE
- (47) Atlas
- (48) Cell Signaling Technology
- (49) GenBank
- (50) H-invDB
- (51) HORDE
- (52) HUGE
- (53) IMGT
- (54) Leiden
- (55) miRBase
- (56) DME
- (57) OriGene
- (58) PubMed
- (59) R&D Systems
- (60) TGDB
- (61) Tocris
- (62) Abcam
- (63) Novus Biologicals
- (64) ProSpec
- (65) Sino Biological
- (66) GenScript
- (67) Qiagen
- (68) Cloud-Clone Corp.
- (69) OCA
- (70) Proteopedia
- (71) MOPED
- (72) neXtProt
- (73) Reactome
- (74) GeneGo (Thomson Reuters)
- (75) fRNAdb
- (76) DISEASES
- (77) SIMAP
- (78) GenomeRNAi
- (79) LifeMap
- (80) miRTarBase
- (81) MalaCards
- (82) Invitrogen
- (83) BitterDB
- (84) Vector BioLabs
- (85) ESI-BIO
- (86) RefSeq
- (87) BioSystems
- (88) MaxQB
- (89) IUPHAR
- (90) BioGPS
- (91) Illumina
- (92) COMPARTMENTS
- (93) HOMER
- (94) PaxDb
- (95) ApexBio
- (96) Addgene
- (97) antibodies-online
- (98) CYP
- (99) NONCODE
- (100) SwitchGear Genomics
- (101) TreeFam
- (102) PathCards
- (103) GeneReviews
- (104) GeneTex
- (105) Taconic Biosciences
- (106) GTEx
- (107) ProteomicsDB
- (108) SCBT
- (109) DGIdb
- (110) ClinicalTrials
- (111) FDA Approved Drugs
- (112) RVIS
- (113) SIGNOR
- (114) diseasecard
- (115) NIH Rare Diseases
- (116) Orphanet
- (117) UMLS
- (118) GTR
- (119) Disease Ontology
- (120) Genetics Home Reference
- (121) MeSH
- (122) MedlinePlus
- (123) CDC
- (124) NINDS
- (125) NCBI Bookshelf
- (126) ClinVar
- (127) Gene Damage Index
- (128) ViGene Biosciences
- (129) HPO
- (130) UDN
- (131) VISTA
- (132) FANTOM5
- (133) ENCODE
- (134) ProSci
- (135) Horizon
- (136) NURSA
- (137) IID
- (138) Cyagen
- (139) VectorBuilder
- (140) SNPedia
- (141) BRCA Exchange
- (142) St John's Lab
- (143) CIViC
- (144) ProteoGenix
- (145) dbSUPER
- (146) TISSUES
- (147) Gene ORGANizer
- (148) abm
- (149) CrownBio
- (150) Human Protein Atlas
- (151) GWAS Catalog
- (152) Monarch Initiative
- (153) DataMed
- (154) HumanCyc
- (155) genomics-online
- (156) UCNEbase
- (157) EPDnew