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TRIM43 (Tripartite Motif Containing 43) is a Protein Coding gene. Diseases associated with TRIM43 include Facioscapulohumeral Muscular Dystrophy 1 and Facioscapulohumeral Muscular Dystrophy 2. An important paralog of this gene is TRIM43B.
GO ID | Qualified GO term | Evidence | PubMed IDs |
---|---|---|---|
GO:0005515 | protein binding | IPI | 25416956 |
GO:0008270 | zinc ion binding | IEA | -- |
GO:0046872 | metal ion binding | IEA | -- |
GO:0061630 | ubiquitin protein ligase activity | IBA | 21873635 |
GO ID | Qualified GO term | Evidence | PubMed IDs |
---|---|---|---|
GO:0005737 | cytoplasm | IBA | 21873635 |
GO ID | Qualified GO term | Evidence | PubMed IDs |
---|---|---|---|
GO:0010468 | regulation of gene expression | IBA | 21873635 |
GO:0016567 | protein ubiquitination | IBA | 21873635 |
GO:0045087 | innate immune response | IBA | 21873635 |
This gene was present in the common ancestor of chordates.
Organism | Taxonomy | Gene | Similarity | Type | Details |
---|---|---|---|---|---|
Chimpanzee (Pan troglodytes) |
Mammalia | LOC739911 30 |
|
||
TRIM43 31 |
|
OneToOne | |||
Cow (Bos Taurus) |
Mammalia | LOC528629 30 |
|
||
TRIM43 31 |
|
OneToOne | |||
Rat (Rattus norvegicus) |
Mammalia | Trim43a 30 |
|
||
Mouse (Mus musculus) |
Mammalia | Trim43c 31 |
|
OneToMany | |
Trim43a 31 |
|
OneToMany | |||
Trim43b 31 |
|
OneToMany | |||
Oppossum (Monodelphis domestica) |
Mammalia | -- 31 |
|
ManyToMany | |
-- 31 |
|
ManyToMany | |||
-- 31 |
|
ManyToMany | |||
-- 31 |
|
ManyToMany | |||
-- 31 |
|
ManyToMany | |||
-- 31 |
|
ManyToMany | |||
-- 31 |
|
ManyToMany | |||
-- 31 |
|
ManyToMany | |||
-- 31 |
|
ManyToMany | |||
-- 31 |
|
ManyToMany | |||
-- 31 |
|
ManyToMany | |||
-- 31 |
|
ManyToMany | |||
-- 31 |
|
ManyToMany | |||
-- 31 |
|
ManyToMany | |||
Platypus (Ornithorhynchus anatinus) |
Mammalia | -- 31 |
|
OneToMany | |
Lizard (Anolis carolinensis) |
Reptilia | -- 31 |
|
ManyToMany | |
-- 31 |
|
ManyToMany | |||
-- 31 |
|
ManyToMany | |||
-- 31 |
|
ManyToMany | |||
-- 31 |
|
ManyToMany | |||
-- 31 |
|
ManyToMany | |||
-- 31 |
|
ManyToMany | |||
Zebrafish (Danio rerio) |
Actinopterygii | trim109 31 |
|
ManyToMany |
Variant ID | Type | Subtype | PubMed ID |
---|---|---|---|
dgv4008n100 | CNV | gain | 25217958 |
esv3575267 | CNV | gain | 25503493 |
esv3591652 | OTHER | inversion | 21293372 |
nsv1008461 | CNV | gain | 25217958 |
nsv222 | OTHER | inversion | 15895083 |
nsv516044 | CNV | gain+loss | 19592680 |
nsv7320 | OTHER | inversion | 18451855 |
nsv834300 | CNV | gain | 17160897 |
nsv961830 | CNV | duplication | 23825009 |
nsv998014 | CNV | gain | 25217958 |
nsv998587 | CNV | gain | 25217958 |
Disorder | Aliases | PubMed IDs |
---|---|---|
facioscapulohumeral muscular dystrophy 1 |
|
|
facioscapulohumeral muscular dystrophy 2 |
|
|
digenic disease |
|
|