Free for academic non-profit institutions. Other users need a Commercial license
This gene encodes a member of the tripartite motif (TRIM) family. The encoded protein contains a RING-type zinc finger, B box-type zinc finger and SPRY domain. The function of this protein has not been identified. A pseudogene of this gene is located on the long arm of chromosome 4. [provided by RefSeq, Jul 2012] See more...
Aliases for TRIM38 Gene
Aliases for TRIM38 Gene
External Ids for TRIM38 Gene
- HGNC: 10059
- Entrez Gene: 10475
- Ensembl: ENSG00000112343
- UniProtKB: O00635
Previous HGNC Symbols for TRIM38 Gene
- RNF15
Previous GeneCards Identifiers for TRIM38 Gene
- GC06P026006
- GC06P026071
- GC06P026070
- GC06P025906
- GC06P025965
- GC06P025966
- GC06P025967
- GC06P025968
- GC06P025969
Summaries for TRIM38 Gene
-
This gene encodes a member of the tripartite motif (TRIM) family. The encoded protein contains a RING-type zinc finger, B box-type zinc finger and SPRY domain. The function of this protein has not been identified. A pseudogene of this gene is located on the long arm of chromosome 4. [provided by RefSeq, Jul 2012]
GeneCards Summary for TRIM38 Gene
TRIM38 (Tripartite Motif Containing 38) is a Protein Coding gene. Among its related pathways are Interferon gamma signaling and Innate Immune System. Gene Ontology (GO) annotations related to this gene include ligase activity and obsolete signal transducer activity. An important paralog of this gene is TRIM21.
UniProtKB/Swiss-Prot Summary for TRIM38 Gene
-
E3 ubiquitin-protein ligase. Mediates 'Lys-48'-linked polyubiquitination and proteasomal degradation of the critical TLR adapter TICAM1, inhibiting TLR3-mediated type I interferon signaling.
Additional gene information for TRIM38 Gene
- HGNC(10059)
- Entrez Gene(10475)
- Ensembl(ENSG00000112343)
- UniProtKB(O00635)
- Open Targets Platform(ENSG00000112343)
- Search for TRIM38 at DataMed
- Search for TRIM38 at HumanCyc
No data available for CIViC Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , Rfam classification and piRNA Summary for TRIM38 Gene
Genomics for TRIM38 Gene
GeneHancer (GH) Regulatory Elements Pubs
Promoters and enhancers for TRIM38 Gene
- Elite GeneHancer and/or Elite GeneHancer-gene association
Download GeneHancer data from 2017 publication |
Request up-to-date GeneHancer data (full dataset)
GeneHancers around TRIM38 on the GeneHancer Hub at the UCSC Golden Path
Cistromic (ChIP-Seq) regulation report from SPP (The Signaling Pathways Project) for TRIM38
- Top Transcription factor binding sites by QIAGEN in the TRIM38 gene promoter:
-
- Bach2
- HNF-4alpha1
- Nkx6-1
- PPAR-alpha
- PPAR-gamma1
- PPAR-gamma2
- STAT5B
- XBP-1
Genomic Locations for TRIM38 Gene
Genomic Locations for TRIM38 Gene
- chr6:25,962,723-25,991,231
- (GRCh38/hg38)
- Size:
- 28,509 bases
- Orientation:
- Plus strand
- chr6:25,963,030-25,987,384
- (GRCh37/hg19)
- Size:
- 24,355 bases
- Orientation:
- Plus strand
Genomic View for TRIM38 Gene
Genes around TRIM38 on UCSC Golden Path with GeneCards custom track
- Cytogenetic band:
-
- 6p22.2 by HGNC
- 6p22.2 by Entrez Gene
- 6p22.2 by Ensembl
TRIM38 Gene in genomic location: bands according to
Ensembl, locations according to GeneLoc
(and/or Entrez Gene and/or Ensembl if different)
Genomic Neighborhood
• Exon Structure
• Gene Density
RefSeq DNA sequence for TRIM38 Gene
Proteins for TRIM38 Gene
-
Protein details for TRIM38 Gene (UniProtKB/Swiss-Prot)
- Protein Symbol:
- O00635-TRI38_HUMAN
- Recommended name:
- E3 ubiquitin-protein ligase TRIM38
- Protein Accession:
- O00635
- B2R862
Protein attributes for TRIM38 Gene
- Size:
- 465 amino acids
- Molecular mass:
- 53416 Da
- Quaternary structure:
- No Data Available
Protein Expression for TRIM38 Gene
Post-translational modifications for TRIM38 Gene
Other Protein References for TRIM38 Gene
- ENSEMBL proteins:
- REFSEQ proteins:
Antibody Products
- LifeSpan BioSciences TRIM38 Antibody
-
Custom Antibody ServicesOriGene Antibodies for TRIM38
- AP20399PU-N
- CF505960
- CF505962
- CF505963
- CF505964
- CF505969
- CF505976
- CF505979
- CF505980
- CF505981
- CF505982
- CF505983
- TA312316
- TA347517
- TA505960
- TA505960S
- TA505962
- TA505962S
- TA505963
- TA505963S
- TA505964
- TA505964S
- TA505969
- TA505969S
- TA505976
- TA505976S
- TA505979
- TA505979S
- TA505980
- TA505980S
- TA505981
- TA505981S
- TA505982
- TA505982S
- TA505983
- TA505983S
- Novus Biologicals Antibodies for TRIM38
-
Abcam antibodies for TRIM38
- Invitrogen Antibodies for TRIM38 (AFLGC-TRIM38)
Protein Products
-
OriGene Purified Proteins for TRIM38
- Search Origene for MassSpec and Protein Over-expression Lysates for TRIM38
- Origene Custom Protein Services for TRIM38
- antibodies-online: Show 3 available TRIM38 Proteins ranked by validation data
- Compare Top TRIM38 Proteins
-
Quality Products:
-
Abcam proteins for TRIM38
Assay Products
-
Boster Bio ELISA Kits for TRIM38
No data available for DME Specific Peptides for TRIM38 Gene
Domains & Families for TRIM38 Gene
Gene Families for TRIM38 Gene
- HGNC:
- Human Protein Atlas (HPA):
-
- Enzymes
- Predicted intracellular proteins
Protein Domains for TRIM38 Gene
- InterPro:
- Blocks:
-
- Zn-finger, RING
- Butyrophylin C-terminal DUF signature
- SPRY-associated domain
- B-box zinc finger signature
- ProtoNet:
Suggested Antigen Peptide Sequences for TRIM38 Gene
- GenScript: Design optimal peptide antigens:
-
- Zinc finger protein RoRet (TRI38_HUMAN)
No data available for Graphical View of Domain Structure and UniProtKB/Swiss-Prot for TRIM38 Gene
Function for TRIM38 Gene
Molecular function for TRIM38 Gene
- UniProtKB/Swiss-Prot Function:
- E3 ubiquitin-protein ligase. Mediates 'Lys-48'-linked polyubiquitination and proteasomal degradation of the critical TLR adapter TICAM1, inhibiting TLR3-mediated type I interferon signaling.
- UniProtKB/Swiss-Prot CatalyticActivity:
- Reaction=S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.; EC=2.3.2.27;.
Enzyme Numbers (IUBMB) for TRIM38 Gene
Phenotypes From GWAS Catalog for TRIM38 Gene
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0005515 | protein binding | IPI | 25416956 |
| GO:0008270 | zinc ion binding | IEA | -- |
| GO:0016740 | transferase activity | IEA | -- |
| GO:0019901 | protein kinase binding | IBA | 21873635 |
| GO:0042803 | protein homodimerization activity | IBA | 21873635 |
Phenotypes for TRIM38 Gene
- MGI mutant phenotypes for TRIM38:
- inferred from 1 alleles
- GenomeRNAi human phenotypes for TRIM38:
Animal Models for TRIM38 Gene
- MGI Knock Outs for TRIM38:
-
- Trim38 Trim38<tm1(KOMP)Vlcg>
Animal Model Products
- Taconic Biosciences: Generate A Custom CRISPR Mouse Model For Your Study
CRISPR Products
- Applied Biological Materials (abm): CRISPR Clones for TRIM38 - Select products 50% OFF >
- * TRIM38 CRISPR as ready-to-use vector or virus: ORF | Lenti- | Adeno- | AAV- | Protein Vector - Browse All
- * Gene synthesis, site-directed mutagenesis, subcloning, and more services - Browse All
-
OriGene CRISPR knockouts for TRIM38
- Search GeneCopoeia for CRISPR/Cas9 clones, lentivirus and AAV products for TRIM38
-
Santa Cruz Biotechnology (SCBT) CRISPR for TRIM38
miRNA for TRIM38 Gene
- miRTarBase miRNAs that target TRIM38
-
- hsa-miR-124-3p (MIRT022126)
- hsa-miR-21-5p (MIRT030670)
- hsa-miR-1273e (MIRT449805)
- hsa-miR-448 (MIRT449806)
- hsa-miR-489-3p (MIRT449807)
- hsa-miR-3913-3p (MIRT449808)
- hsa-miR-586 (MIRT449809)
- hsa-miR-29b-2-5p (MIRT560606)
- hsa-miR-6079 (MIRT560607)
- hsa-miR-876-3p (MIRT560608)
- hsa-miR-323a-5p (MIRT560609)
- hsa-miR-6077 (MIRT560610)
- hsa-miR-600 (MIRT560611)
- hsa-miR-4705 (MIRT560612)
- hsa-miR-34b-3p (MIRT560613)
- hsa-miR-6765-5p (MIRT646579)
- hsa-miR-1304-5p (MIRT646580)
- hsa-miR-4775 (MIRT646581)
- hsa-miR-502-5p (MIRT646582)
- hsa-miR-1827 (MIRT646583)
- hsa-miR-129-5p (MIRT783623)
- hsa-miR-3194-3p (MIRT784795)
- hsa-miR-3607-3p (MIRT784940)
- hsa-miR-3672 (MIRT785166)
- hsa-miR-3686 (MIRT785233)
- hsa-miR-431-5p (MIRT785740)
- hsa-miR-4524a-3p (MIRT786142)
- hsa-miR-4633-3p (MIRT786239)
- hsa-miR-5691 (MIRT787772)
- hsa-miR-624-3p (MIRT788139)
- hsa-miR-6500-5p (MIRT788206)
- hsa-miR-6805-3p (MIRT788851)
- hsa-miR-6864-3p (MIRT789171)
- hsa-miR-6874-5p (MIRT789252)
- hsa-miR-8055 (MIRT789743)
miRNA Products
Inhibitory RNA Products
- Origene shrna, sirna, and RNAi products in human, mouse, rat for TRIM38
- Browse OriGene Inhibitory RNA Products For TRIM38
- Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for TRIM38
Clone Products
- Applied Biological Materials (abm): Clones for TRIM38 - Select products 50% OFF >
- * TRIM38 as ready-to-use vector or virus: ORF | Lenti- | Retro- | Adeno- | AAV- | Protein Vector - Browse All
- * Gene synthesis, site-directed mutagenesis, subcloning, and more services - Browse All
- Sino Biological Human cDNA Clone for TRIM38
- Search GeneCopoeia for ORF cDNA, lentivirus, AAV viral particles and/or promoter clone products for TRIM38
Cell Line Products
-
Horizon Cell Lines for TRIM38
No data available for Human Phenotype Ontology , Transcription Factor Targets and HOMER Transcription for TRIM38 Gene
Localization for TRIM38 Gene
| Compartment | Confidence |
|---|---|
| cytosol | 5 |
| nucleus | 3 |
| plasma membrane | 2 |
| cytoskeleton | 2 |
| lysosome | 2 |
| extracellular | 1 |
| mitochondrion | 1 |
| endoplasmic reticulum | 1 |
| endosome | 1 |
- Cell Junctions (2)
- Centrosome (2)
- Plasma membrane (2)
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0005575 | cellular_component | ND | -- |
| GO:0005654 | nucleoplasm | IBA | 21873635 |
| GO:0005737 | cytoplasm | IBA | 21873635 |
| GO:0005829 | cytosol | TAS | -- |
No data available for Subcellular locations from UniProtKB/Swiss-Prot for TRIM38 Gene
Pathways & Interactions for TRIM38 Gene
| SuperPathway | Contained pathways | ||
|---|---|---|---|
| 1 | Interferon gamma signaling | ||
| 2 | Cytokine Signaling in Immune system | ||
| 3 | Innate Immune System |
.61
|
|
Pathways by source for TRIM38 Gene
4 Reactome pathways for TRIM38 Gene
UniProtKB/Swiss-Prot O00635-TRI38_HUMAN
- Pathway: Protein modification; protein ubiquitination.
Interacting Proteins for TRIM38 Gene
Selected Interacting proteins:
O00635-TRI38_HUMAN
ENSP00000349596
for TRIM38 Gene via
UniProtKB
MINT
STRING
IID
GPS-Prot Interaction Network for TRIM38
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0000209 | protein polyubiquitination | IBA | 21873635 |
| GO:0002376 | immune system process | IEA | -- |
| GO:0010468 | regulation of gene expression | IBA | 21873635 |
| GO:0010508 | positive regulation of autophagy | IBA | 21873635 |
| GO:0016567 | protein ubiquitination | IEA,IBA | 21873635 |
No data available for SIGNOR curated interactions for TRIM38 Gene
Transcripts for TRIM38 Gene
mRNA/cDNA for TRIM38 Gene
- 1 REFSEQ mRNAs :
- 8 NCBI additional mRNA sequence :
- 1 Ensembl transcripts including schematic representations, and UCSC links to gene/alias where relevant :
-
- ENST00000357085 9418 nts (view in UCSC)
CRISPR Products
- Applied Biological Materials (abm): CRISPR Clones for TRIM38 - Select products 50% OFF >
- * TRIM38 CRISPR as ready-to-use vector or virus: ORF | Lenti- | Adeno- | AAV- | Protein Vector - Browse All
- * Gene synthesis, site-directed mutagenesis, subcloning, and more services - Browse All
-
OriGene CRISPR knockouts for TRIM38
- Search GeneCopoeia for CRISPR/Cas9 clones, lentivirus and AAV products for TRIM38
-
Santa Cruz Biotechnology (SCBT) CRISPR for TRIM38
miRNA Products
Inhibitory RNA Products
- Origene shrna, sirna, and RNAi products in human, mouse, rat for TRIM38
- Browse OriGene Inhibitory RNA Products For TRIM38
- Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for TRIM38
Clone Products
- Applied Biological Materials (abm): Clones for TRIM38 - Select products 50% OFF >
- * TRIM38 as ready-to-use vector or virus: ORF | Lenti- | Retro- | Adeno- | AAV- | Protein Vector - Browse All
- * Gene synthesis, site-directed mutagenesis, subcloning, and more services - Browse All
- Sino Biological Human cDNA Clone for TRIM38
- Search GeneCopoeia for ORF cDNA, lentivirus, AAV viral particles and/or promoter clone products for TRIM38
| ExUns: | 1a | · | 1b | · | 1c | · | 1d | · | 1e | ^ | 2 | ^ | 3 | ^ | 4 | ^ | 5 | ^ | 6a | · | 6b | · | 6c | · | 6d | · | 6e | ^ | 7 | ^ | 8 | ^ | 9a | · | 9b | ^ | 10 | ^ | 11a | · | 11b |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| SP1: | - | - | |||||||||||||||||||||||||||||||||||||||
| SP2: | - | ||||||||||||||||||||||||||||||||||||||||
| SP3: | |||||||||||||||||||||||||||||||||||||||||
| SP4: | - | - | |||||||||||||||||||||||||||||||||||||||
| SP5: | - | - | - | ||||||||||||||||||||||||||||||||||||||
| SP6: | - | ||||||||||||||||||||||||||||||||||||||||
| SP7: | - | - | |||||||||||||||||||||||||||||||||||||||
| SP8: |
Relevant External Links for TRIM38 Gene
- GeneLoc Exon Structure for
- TRIM38
Expression for TRIM38 Gene
mRNA differential expression in normal tissues according to GTEx for TRIM38 Gene
This gene is overexpressed in Whole Blood (x4.7).
This gene is overexpressed in Bone marrow stromal cell (15.5), Lymph node (12.0), and Peripheral blood mononuclear cells (7.9).
Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, MaxQB, and MOPED for TRIM38 Gene
Transcriptomic regulation report from SPP (The Signaling Pathways Project) for TRIM38
SOURCE GeneReport for Unigene cluster for TRIM38 Gene:
Hs.584851mRNA Expression by UniProt/SwissProt for TRIM38 Gene:
O00635-TRI38_HUMAN
Tissue specificity:
Ubiquitous.
Evidence on tissue expression from TISSUES for TRIM38 Gene
- Lung(4.4)
- Liver(4.3)
- Spleen(2.5)
- Kidney(2.5)
- Lymph node(2.1)
- Nervous system(2.1)
- Blood(2.1)
Primer Products
-
OriGene qPCR primer pairs for TRIM38
Gene Expression Assay Products
No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery and Phenotype-based relationships between genes and organs from Gene ORGANizer for TRIM38 Gene
Orthologs for TRIM38 Gene
This gene was present in the common ancestor of chordates.
| Organism | Taxonomy | Gene | Similarity | Type | Details |
|---|---|---|---|---|---|
| Chimpanzee (Pan troglodytes) |
Mammalia | TRIM38 30 31 |
|
OneToOne | |
| Cow (Bos Taurus) |
Mammalia | TRIM38 30 31 |
|
OneToOne | |
| Dog (Canis familiaris) |
Mammalia | TRIM38 30 31 |
|
OneToOne | |
| Mouse (Mus musculus) |
Mammalia | Trim38 30 17 31 |
|
OneToOne | |
| Rat (Rattus norvegicus) |
Mammalia | LOC680019 30 |
|
||
| Chicken (Gallus gallus) |
Aves | -- 31 |
|
OneToMany | |
| Lizard (Anolis carolinensis) |
Reptilia | -- 31 |
|
OneToMany |
- Species where no ortholog for TRIM38 was found in the sources mined by GeneCards:
-
- A. gosspyii yeast (Eremothecium gossypii)
- Actinobacteria (Mycobacterium tuberculosis)
- African clawed frog (Xenopus laevis)
- African malaria mosquito (Anopheles gambiae)
- Alicante grape (Vitis vinifera)
- Alpha proteobacteria (Wolbachia pipientis)
- Amoeba (Dictyostelium discoideum)
- Archea (Pyrococcus horikoshii)
- Baker's yeast (Saccharomyces cerevisiae)
- Barley (Hordeum vulgare)
- Beta proteobacteria (Neisseria meningitidis)
- Bread mold (Neurospora crassa)
- Chromalveolata (Phytophthora infestans)
- Common water flea (Daphnia pulex)
- Corn (Zea mays)
- E. coli (Escherichia coli)
- Filamentous fungi (Aspergillus nidulans)
- Firmicute Bacteria (Streptococcus pneumoniae)
- Fission Yeast (Schizosaccharomyces pombe)
- Fruit Fly (Drosophila melanogaster)
- Green Algae (Chlamydomonas reinhardtii)
- Honey Bee (Apis mellifera)
- K. Lactis Yeast (Kluyveromyces lactis)
- Loblloly Pine (Pinus taeda)
- Malaria Parasite (Plasmodium falciparum)
- Medicago Trunc (Medicago Truncatula)
- Moss (Physcomitrella patens)
- Oppossum (Monodelphis domestica)
- Orangutan (Pongo pygmaeus)
- Pig (Sus scrofa)
- Platypus (Ornithorhynchus anatinus)
- Rainbow Trout (Oncorhynchus mykiss)
- Rice (Oryza sativa)
- Rice Blast Fungus (Magnaporthe grisea)
- Schistosome Parasite (Schistosoma mansoni)
- Sea Anemone (Nematostella vectensis)
- Sea Vase (Ciona intestinalis)
- Sea Squirt (Ciona savignyi)
- Sea Urchin (Strongylocentrotus purpuratus)
- Sorghum (Sorghum bicolor)
- Soybean (Glycine max)
- Stem Rust Fungus (Puccinia graminis)
- Sugarcane (Saccharum officinarum)
- Thale Cress (Arabidopsis thaliana)
- Tomato (Lycopersicon esculentum)
- Toxoplasmosis (Toxoplasma gondii)
- Trichoplax (Trichoplax adhaerens)
- Tropical Clawed Frog (Silurana tropicalis)
- Wheat (Triticum aestivum)
- Worm (Caenorhabditis elegans)
- Zebrafish (Danio rerio)
Evolution for TRIM38 Gene
- ENSEMBL:
- Gene Tree for TRIM38 (if available)
- TreeFam:
- Gene Tree for TRIM38 (if available)
- Aminode:
- Evolutionary constrained regions (ECRs) for TRIM38: view image
Paralogs for TRIM38 Gene
Paralogs for TRIM38 Gene
- TRIM21 5
- TRIM58 5
- TRIM6 5
- TRIM26 5
- TRIM10 5
- TRIM39 5
- TRIM27 5
- TRIM11 5
- TRIM34 5
- TRIM22 5
- TRIM6-TRIM34 5
- TRIM5 5
- TRIM7 5
- TRIM68 5
- TRIM41 5
- TRIM75P 5
- MEFV 5
- TRIM72 5
- TRIM15 5
- TRIM17 5
- TRIM69 5
- TRIM60 5
- TRIM62 5
- TRIML1 5
- TRIM4 5
- TRIM3 5
- TRIM50 5
- TRIM39-RPP21 5
- TRIM2 5
- TRIM56 5
- TRIM9 5
- MID1 5
- TRIM67 5
- TRIM25 5
- TRIML2 5
- TRIM71 5
- TRIM77 5
- TRIM64B 5
- TRIM64 5
- TRIM64C 5
- TRIM16 5
- TRIM32 5
- MID2 5
- TRIM43B 5
- TRIM43 5
- TRIM14 5
- TRIM66 5
- TRIM29 5
- TRIM33 5
- TRIM49B 5
- TRIM31 5
- TRIM47 5
- TRIM35 5
- TRIM49D1 5
- TRIM49D2 5
- TRIM42 5
- TRIM51 5
- TRIM24 5
- TRIM65 5
- TRIM49 5
- TRIM49C 5
- TRIM51GP 5
- RNF39 5
- TRIM28 5
- TRIM40 5
- TRIM55 5
- TRIM46 5
- TRIM54 5
- TRIM16L 5
- TRIM45 5
- TRIM63 5
- TRIM37 5
- TRIM36 5
- PML 5
- TRIM13 5
- TRIM8 5
- TRIM73 5
- TRIM52 5
- TRIM74 5
- TRIM48 5
- TRIM61 5
- BSPRY 5
- TRIM44 5
- ENSG00000239920 5
(29) SIMAP similar genes for TRIM38 Gene using alignment to 1 proteins:
- TRI38_HUMAN
Pseudogenes.org Pseudogenes for TRIM38 Gene
Variants for TRIM38 Gene
Sequence variations, with clinical significance, from ClinVar and Humsavar, with links to dbSNP for TRIM38 Gene
| SNP ID | Clinical significance and condition | Chr 06 pos | Variation | AA Info | Type |
|---|---|---|---|---|---|
| rs10317 | - | p.Gly421Arg |
| Variant ID | Type | Subtype | PubMed ID |
|---|---|---|---|
| nsv1023453 | CNV | gain | 25217958 |
| nsv428137 | CNV | loss | 18775914 |
Residual Variation Intolerance Score:
78.4% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score:
4.32;
63.04% of all genes are more intolerant (likely to be disease-causing)
Additional Variant Information for TRIM38 Gene
SNP Genotyping and Copy Number Assay Products
No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for TRIM38 Gene
Disorders for TRIM38 Gene
Additional Disease Information for TRIM38
- Genetic Association Database
- (GAD)
- Human Genome Epidemiology Navigator
- (HuGE)
- ATLAS of Genetics and Cytogenetics in Oncology and Haematology
- Open Targets Platform
No disorders were found for TRIM38 Gene.
No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for TRIM38 Gene
Publications for TRIM38 Gene
- TRIM38 negatively regulates TLR3-mediated IFN-β signaling by targeting TRIF for degradation. (PMID: 23056470) Xue Q … Hung T (PloS one 2012) 3 4
- Variants in TF and HFE explain approximately 40% of genetic variation in serum-transferrin levels. (PMID: 19084217) Benyamin B … Visscher PM (American journal of human genetics 2009) 3 41
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard DS … MGC Project Team (Genome research 2004) 3 4
- A 1.1-Mb transcript map of the hereditary hemochromatosis locus. (PMID: 9149941) Ruddy DA … Feder JN (Genome research 1997) 3 4
- A reference map of the human binary protein interactome. (PMID: 32296183) Luck K … Calderwood MA (Nature 2020) 3
ExternalLinks
Products for TRIM38 Gene
- Custom Antibody ServicesOriGene Antibodies for TRIM38
- AP20399PU-N
- CF505960
- CF505962
- CF505963
- CF505964
- CF505969
- CF505976
- CF505979
- CF505980
- CF505981
- CF505982
- CF505983
- TA312316
- TA347517
- TA505960
- TA505960S
- TA505962
- TA505962S
- TA505963
- TA505963S
- TA505964
- TA505964S
- TA505969
- TA505969S
- TA505976
- TA505976S
- TA505979
- TA505979S
- TA505980
- TA505980S
- TA505981
- TA505981S
- TA505982
- TA505982S
- TA505983
- TA505983S
- Browse OriGene ELISA Kits
- Custom Assay Services
- OriGene Purified Proteins for TRIM38
- Search Origene for MassSpec and Protein Over-expression Lysates for TRIM38
- Origene Custom Protein Services for TRIM38
- Origene shrna, sirna, and RNAi products in human, mouse, rat for TRIM38
- Browse OriGene Inhibitory RNA Products For TRIM38
- OriGene qPCR primer pairs for TRIM38
- OriGene CRISPR knockouts for TRIM38
- Custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
- Browse OriGene miRNA Products For TRIM38
- Sino Biological Human cDNA Clone for TRIM38
- Browse Sino Biological Recombinant Proteins
- Browse Sino Biological Cell Lysates
- Browse Sino Biological Antibodies
- Browse Sino Biological Assays
- Browse cDNA Clones
- Browse ELISA Kits
- Browse CRO Services
- High-throughput Antibody Production Service
- Protein Production Service
- Epitope Tag Antibodies & Reporter Protein Antibodies
- Lentiviral ORF Clones
- Novus Biologicals Antibodies for TRIM38
- Novus Biologicals proteins and lysates for TRIM38
- Browse Antibodies
- Browse Peptides and Proteins
- Browse Lysates
- Browse ELISA Kits
- Abcam antibodies for TRIM38
- Abcam proteins for TRIM38
- Find your target
- Browse Primary Antibodies
- Browse Conjugated Primary Antibodies
- Browse Secondary Antibodies
- Browse ELISA Kits
- Browse Matched Antibody Pairs
- Browse Proteins and Peptides
- Search Knockout (KO) Validated Antibodies
- Browse Monoclonal Antibodies
- Browse Recombinant Antibodies
- Invitrogen Antibodies for TRIM38 (AFLGC-TRIM38)
- VectorBuilder Custom and pre-made DNA vectors for TRIM38 (ie. gene expression, shRNA knockdown, CRISPR)
- VectorBuilder Viral vectors for TRIM38 (ie. lentivirus, AAV, adenovirus)
- VectorBuilder CRISPR vectors for TRIM38 (ie. knockout, knockin, CRISPRa, CRISPRi)
- VectorBuilder Virus packaging for TRIM38 CRISPR vectors (ie. lentivirus, AAV, adenovirus)
- VectorBuilder Stable cell line generation for TRIM38
- antibodies-online: Show 32 available TRIM38 Antibodies ranked by validation data
- Compare Top TRIM38 Antibodies
- antibodies-online: Search results for available TRIM38 related products ranked by validation data
- antibodies-online: Show 3 available TRIM38 Proteins ranked by validation data
- Compare Top TRIM38 Proteins
- Quality Products:
- Horizon Cell Lines for TRIM38
- Browse GeneCopoeia Cell Lines
- Search GeneCopoeia for CRISPR/Cas9 clones, lentivirus and AAV products for TRIM38
- Search GeneCopoeia for ORF cDNA, lentivirus, AAV viral particles and/or promoter clone products for TRIM38
- Search GeneCopoeia for miRNA 3'UTR Target clone products for TRIM38
- Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for TRIM38
Sources for TRIM38 Gene
- (1) GeneCards
- (2) HGNC
- (3) NCBI Entrez Gene
- (4) UniProtKB/Swiss-Prot
- (5) Ensembl
- (6) OMIM
- (7) GeneLoc
- (8) Gene Wiki
- (9) UCSC
- (10) PhosphoSitePlus
- (11) Cell Signaling Technology
- (12) GO
- (13) UniProtKB/TrEMBL
- (14) InterPro
- (15) ProtoNet
- (16) Blocks
- (17) MGI
- (18) IUBMB
- (19) KEGG
- (20) MINT
- (21) STRING
- (22) IntAct
- (23) Novoseek
- (24) PharmGKB
- (25) DrugBank
- (26) HMDB
- (27) ASD
- (28) SAGE
- (29) SOURCE
- (30) HomoloGene
- (31) PanEnsembl
- (32) euGenes
- (33) SGD
- (34) FlyBase
- (35) WormBase
- (36) Pseudogene
- (37) DGV
- (38) dbSNP
- (39) GenAtlas
- (40) HGMD
- (41) GAD
- (42) BGMUT
- (43) HuGE
- (44) Atlas
- (45) GenBank
- (46) HORDE
- (47) HUGE
- (48) IMGT
- (49) Leiden
- (50) miRBase
- (51) DME
- (52) OriGene
- (53) PubMed
- (54) R&D Systems
- (55) TGDB
- (56) Tocris
- (57) Abcam
- (58) Novus Biologicals
- (59) ProSpec
- (60) Sino Biological
- (61) GenScript
- (62) Qiagen
- (63) OCA
- (64) Proteopedia
- (65) MOPED
- (66) neXtProt
- (67) Reactome
- (68) GeneGo (Thomson Reuters)
- (69) DISEASES
- (70) SIMAP
- (71) GenomeRNAi
- (72) LifeMap
- (73) miRTarBase
- (74) MalaCards
- (75) Invitrogen
- (76) BitterDB
- (77) ESI-BIO
- (78) RefSeq
- (79) BioSystems
- (80) MaxQB
- (81) IUPHAR
- (82) BioGPS
- (83) Illumina
- (84) COMPARTMENTS
- (85) HOMER
- (86) PaxDb
- (87) ApexBio
- (88) Addgene
- (89) antibodies-online
- (90) CYP
- (91) NONCODE
- (92) TreeFam
- (93) PathCards
- (94) GeneReviews
- (95) GeneTex
- (96) Taconic Biosciences
- (97) GTEx
- (98) ProteomicsDB
- (99) SCBT
- (100) DGIdb
- (101) ClinicalTrials
- (102) RVIS
- (103) SIGNOR
- (104) diseasecard
- (105) NIH Rare Diseases
- (106) Orphanet
- (107) UMLS
- (108) GTR
- (109) Disease Ontology
- (110) Genetics Home Reference
- (111) MeSH
- (112) MedlinePlus
- (113) CDC
- (114) NINDS
- (115) NCBI Bookshelf
- (116) ClinVar
- (117) Gene Damage Index
- (118) HPO
- (119) UDN
- (120) VISTA
- (121) FANTOM5
- (122) ENCODE
- (123) ProSci
- (124) Horizon
- (125) The Signaling Pathways Project (SPP)
- (126) IID
- (127) VectorBuilder
- (128) SNPedia
- (129) BRCA Exchange
- (130) CIViC
- (131) ProteoGenix
- (132) dbSUPER
- (133) TISSUES
- (134) Gene ORGANizer
- (135) abm
- (136) Human Protein Atlas
- (137) GWAS Catalog
- (138) Monarch Initiative
- (139) DataMed
- (140) HumanCyc
- (141) UCNEbase
- (142) EPDnew
- (143) Applied Biosystems
- (144) GlyConnect
- (145) Aminode
- (146) GeneCopoeia
- (147) GPS-Prot
- (148) RNACentral
- (149) LncRNADisease
- (150) LOVD
- (151) miR2Disease
- (152) DiseaseEnhancer
- (153) Boster Bio
- (154) Biorbyt
- (155) Biocompare
- (156) Mastermind
- (157) CTD^2 Dashboard
- (158) CraniofacialAtlas
- (159) GeneImprint
- (160) Synthego
- (161) ENA
- (162) GtRNAdb
- (163) LncBase
- (164) LncBook
- (165) LNCipedia
- (166) Modomics
- (167) PDBe
- (168) Rfam
- (169) SILVA
- (170) snOPY
- (171) SRPDB
- (172) GENCODE
- (173) TarBase
- (174) Signalway Antibody
- (175) Open Targets Platform
- (176) 5SRRNADB
- (177) snoDB
- (178) MirGeneDB