Aliases for TRIM34 Gene
External Ids for TRIM34 Gene
Previous HGNC Symbols for TRIM34 Gene
Previous GeneCards Identifiers for TRIM34 Gene
The protein encoded by this gene is a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, B-box type 1 and B-box type 2 domain, and a coiled-coil region. Expression of this gene is up-regulated by interferon. This gene is mapped to chromosome 11p15, where it resides within a TRIM gene cluster. Alternative splicing results in multiple transcript variants. A read-through transcript from the upstream TRIM6 gene has also been observed, which results in a fusion product from these neighboring family members. [provided by RefSeq, Oct 2010]
GeneCards Summary for TRIM34 Gene
TRIM34 (Tripartite Motif Containing 34) is a Protein Coding gene. Diseases associated with TRIM34 include Hypotrichosis-Lymphedema-Telangiectasia-Renal Defect Syndrome. Among its related pathways are Interferon gamma signaling and Innate Immune System. An important paralog of this gene is TRIM6-TRIM34.
UniProtKB/Swiss-Prot Summary for TRIM34 Gene
May function as antiviral protein and may contribute to the defense against retroviral infections.