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TRIAP1 (TP53 Regulated Inhibitor Of Apoptosis 1) is a Protein Coding gene. Diseases associated with TRIAP1 include Immune-Complex Glomerulonephritis and Autoimmune Glomerulonephritis. Among its related pathways are TP53 Regulates Transcription of Cell Death Genes and Gene Expression. Gene Ontology (GO) annotations related to this gene include p53 binding and phosphatidic acid transporter activity.
GO ID | Qualified GO term | Evidence | PubMed IDs |
---|---|---|---|
GO:0002039 | p53 binding | IPI | 15735003 |
GO:0005515 | protein binding | IPI | 15735003 |
GO:1990050 | contributes_to phosphatidic acid transporter activity | IDA | 23931759 |
GO ID | Qualified GO term | Evidence | PubMed IDs |
---|---|---|---|
GO:0005654 | nucleoplasm | IDA | -- |
GO:0005737 | cytoplasm | IEA | -- |
GO:0005739 | mitochondrion | IEA,IDA | 15735003 |
GO:0005758 | mitochondrial intermembrane space | TAS | -- |
GO:0032991 | protein-containing complex | IDA | 23931759 |
SuperPathway | Contained pathways | ||
---|---|---|---|
1 | Gene Expression |
.48
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2 | TP53 Regulates Transcription of Cell Death Genes | ||
3 | Regulation of TP53 Activity | ||
4 | Direct p53 effectors |
GO ID | Qualified GO term | Evidence | PubMed IDs |
---|---|---|---|
GO:0006869 | lipid transport | IEA | -- |
GO:0006915 | apoptotic process | IEA | -- |
GO:0006977 | DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest | TAS | 15735003 |
GO:0015914 | phospholipid transport | IDA | 26071602 |
GO:0030330 | DNA damage response, signal transduction by p53 class mediator | IDA | 15735003 |
This gene was present in the common ancestor of animals.
Organism | Taxonomy | Gene | Similarity | Type | Details |
---|---|---|---|---|---|
Chimpanzee (Pan troglodytes) |
Mammalia | TRIAP1 30 31 |
|
OneToOne | |
Cow (Bos Taurus) |
Mammalia | TRIAP1 30 31 |
|
OneToOne | |
Oppossum (Monodelphis domestica) |
Mammalia | -- 31 |
|
OneToMany | |
-- 31 |
|
OneToMany | |||
Mouse (Mus musculus) |
Mammalia | Triap1 30 17 31 |
|
OneToOne | |
Dog (Canis familiaris) |
Mammalia | TRIAP1 30 31 |
|
OneToOne | |
Rat (Rattus norvegicus) |
Mammalia | Triap1 30 |
|
||
Chicken (Gallus gallus) |
Aves | TRIAP1 30 31 |
|
OneToOne | |
Lizard (Anolis carolinensis) |
Reptilia | TRIAP1 31 |
|
OneToOne | |
Tropical Clawed Frog (Silurana tropicalis) |
Amphibia | triap1 30 |
|
||
African clawed frog (Xenopus laevis) |
Amphibia | Xl.20201 30 |
|
||
Zebrafish (Danio rerio) |
Actinopterygii | triap1 30 31 |
|
OneToOne | |
Dr.17876 30 |
|
||||
Rainbow Trout (Oncorhynchus mykiss) |
Actinopterygii | Omy.7129 30 |
|
||
Fruit Fly (Drosophila melanogaster) |
Insecta | CG30108 31 |
|
OneToMany | |
CG30109 31 |
|
OneToMany |
Disorder | Aliases | PubMed IDs |
---|---|---|
immune-complex glomerulonephritis |
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autoimmune glomerulonephritis |
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autoimmune disease of urogenital tract |
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spastic ataxia 5 |
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autoimmune disease of musculoskeletal system |
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