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Aliases for TRGV8 Gene

Aliases for TRGV8 Gene

  • T Cell Receptor Gamma Variable 8 2 3
  • T-Cell Receptor, Gamma, Variable Region V8 2 3
  • TCRGV8 2 3
  • T-Cell Receptor Gamma Variable 8 5
  • V1S8 3

External Ids for TRGV8 Gene

Previous HGNC Symbols for TRGV8 Gene

  • TCRGV8

Previous GeneCards Identifiers for TRGV8 Gene

  • GC07U990113
  • GC07M038076
  • GC07M038110
  • GC07M038144
  • GC07M038336
  • GC07M038374
  • GC07M038411
  • GC07M038382
  • GC07M038414
  • GC07M038434
  • GC07M038679
  • GC07M038907
  • GC07M039136
  • GC07M039367
  • GC07M038448
  • GC07M038456
  • GC07M038469
  • GC07M038482
  • GC07M038494
  • GC07M038508
  • GC07M038520

Summaries for TRGV8 Gene

GeneCards Summary for TRGV8 Gene

TRGV8 (T Cell Receptor Gamma Variable 8) is a Protein Coding gene. An important paralog of this gene is TRGV4.

Additional gene information for TRGV8 Gene

No data available for Entrez Gene Summary , CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for TRGV8 Gene

Genomics for TRGV8 Gene

GeneHancer (GH) Regulatory Elements for TRGV8 Gene

Promoters and enhancers for TRGV8 Gene
GeneHancer (GH) Identifier GH Type GH
Score
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH07I038329 Enhancer 1.4 FANTOM5 Ensembl ENCODE dbSUPER 550.8 -0.1 -141 2.6 HDAC1 ZNF335 ZNF143 ATF7 CAVIN1 ELF1 HDAC8 ZNF592 MEF2D NFIC ENSG00000272908 TRGV8 STARD3NL TRGV5P TARP GC07P038328 TRGV7 TRG
GH07I038332 Enhancer 0.7 dbSUPER 0.8 -2.2 -2212 1.3 ZNF740 CAVIN1 NR4A1 BACH1 GTF2A2 HDAC8 ZNF354B ZNF395 RELA ZNF592 ENSG00000272908 TRGV7 TRGV8 TRG
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data dump

GeneHancers around TRGV8 on UCSC Golden Path with GeneCards custom track

Genomic Locations for TRGV8 Gene

Genomic Locations for TRGV8 Gene
chr7:38,330,343-38,330,935
(GRCh38/hg38)
Size:
593 bases
Orientation:
Minus strand
chr7:38,369,944-38,370,536
(GRCh37/hg19)

Genomic View for TRGV8 Gene

Genes around TRGV8 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
TRGV8 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for TRGV8 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for TRGV8 Gene

Proteins for TRGV8 Gene

  • Protein details for TRGV8 Gene (UniProtKB/TrEMBL)

    Protein Symbol:
    A0A0C4DH27
    Recommended name:
    T-cell receptor gamma variable 8
    Protein Accession:
    A0A0C4DH27

    Protein attributes for TRGV8 Gene

    Size:
    118 amino acids
    Molecular mass:
    13335 Da
    Quaternary structure:
    No Data Available

neXtProt entry for TRGV8 Gene

Post-translational modifications for TRGV8 Gene

No Post-translational modifications

Other Protein References for TRGV8 Gene

ENSEMBL proteins:

No data available for DME Specific Peptides for TRGV8 Gene

Domains & Families for TRGV8 Gene

Gene Families for TRGV8 Gene

Protein Domains for TRGV8 Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with TRGV8: view

No data available for Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for TRGV8 Gene

Function for TRGV8 Gene

Animal Model Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes From GWAS Catalog , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for TRGV8 Gene

Localization for TRGV8 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for TRGV8 Gene

Pathways & Interactions for TRGV8 Gene

SuperPathways for TRGV8 Gene

No Data Available

Interacting Proteins for TRGV8 Gene

Gene Ontology (GO) - Biological Process for TRGV8 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for TRGV8 Gene

Drugs & Compounds for TRGV8 Gene

No Compound Related Data Available

Transcripts for TRGV8 Gene

mRNA/cDNA for TRGV8 Gene

Clone Products

Alternative Splicing Database (ASD) splice patterns (SP) for TRGV8 Gene

No ASD Table

Relevant External Links for TRGV8 Gene

GeneLoc Exon Structure for
TRGV8
ECgene alternative splicing isoforms for
TRGV8

Expression for TRGV8 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for TRGV8 Gene

mRNA differential expression in normal tissues according to GTEx for TRGV8 Gene

This gene is overexpressed in Whole Blood (x21.2) and Spleen (x6.0).

NURSA nuclear receptor signaling pathways regulating expression of TRGV8 Gene:

TRGV8
genes like me logo Genes that share expression patterns with TRGV8: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for TRGV8 Gene

Orthologs for TRGV8 Gene

This gene was present in the common ancestor of mammals.

Orthologs for TRGV8 Gene

Organism Taxonomy Gene Similarity Type Details
cow
(Bos Taurus)
Mammalia -- 34
  • 59 (a)
OneToMany
platypus
(Ornithorhynchus anatinus)
Mammalia -- 34
  • 40 (a)
ManyToMany
-- 34
  • 40 (a)
ManyToMany
-- 34
  • 38 (a)
ManyToMany
-- 34
  • 35 (a)
ManyToMany
-- 34
  • 35 (a)
ManyToMany
-- 34
  • 33 (a)
ManyToMany
-- 34
  • 32 (a)
ManyToMany
-- 34
  • 31 (a)
ManyToMany
-- 34
  • 22 (a)
ManyToMany
Species where no ortholog for TRGV8 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • chimpanzee (Pan troglodytes)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • dog (Canis familiaris)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • mouse (Mus musculus)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for TRGV8 Gene

ENSEMBL:
Gene Tree for TRGV8 (if available)
TreeFam:
Gene Tree for TRGV8 (if available)

Paralogs for TRGV8 Gene

Paralogs for TRGV8 Gene

genes like me logo Genes that share paralogs with TRGV8: view

Variants for TRGV8 Gene

Additional Variant Information for TRGV8 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
TRGV8

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Sequence variations from dbSNP and Humsavar , Structural Variations from Database of Genomic Variants (DGV) and Variation tolerance for TRGV8 Gene

Disorders for TRGV8 Gene

No disorders were found for TRGV8 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot , Genatlas and External Links for TRGV8 Gene

Publications for TRGV8 Gene

  1. The human T-cell receptor gamma (TRG) genes. (PMID: 2527426) Lefranc MP … Rabbitts TH (Trends in biochemical sciences 1989) 3 58
  2. Variable region genes in the human T-cell rearranging gamma (TRG) locus: V-J junction and homology with the mouse genes. (PMID: 2969332) Huck S … Lefranc MP (The EMBO journal 1988) 3 58
  3. Diversity and rearrangement of the human T cell rearranging gamma genes: nine germ-line variable genes belonging to two subgroups. (PMID: 2938743) LeFranc MP … Rabbitts TH (Cell 1986) 3 58

Products for TRGV8 Gene

Sources for TRGV8 Gene

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