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Aliases for TRGV5 Gene

Aliases for TRGV5 Gene

  • T Cell Receptor Gamma Variable 5 2 3
  • T-Cell Receptor, Gamma, Variable Region V5 2 3
  • TCRGV5 2 3
  • T-Cell Receptor Gamma Variable 5 5
  • T-Cell Gamma Precursor Protein 3
  • V1S5 3

External Ids for TRGV5 Gene

Previous HGNC Symbols for TRGV5 Gene

  • TCRGV5

Previous GeneCards Identifiers for TRGV5 Gene

  • GC07U990109
  • GC07M038095
  • GC07M038129
  • GC07M038162
  • GC07M038351
  • GC07M038388
  • GC07M038426
  • GC07M038451
  • GC07M038459
  • GC07M038473
  • GC07M038485
  • GC07M038497
  • GC07M038511
  • GC07M038523

Summaries for TRGV5 Gene

GeneCards Summary for TRGV5 Gene

TRGV5 (T Cell Receptor Gamma Variable 5) is a Protein Coding gene. An important paralog of this gene is TRGV3.

Additional gene information for TRGV5 Gene

No data available for Entrez Gene Summary , CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for TRGV5 Gene

Genomics for TRGV5 Gene

GeneHancer (GH) Regulatory Elements for TRGV5 Gene

Promoters and enhancers for TRGV5 Gene
GeneHancer (GH) Identifier GH Type GH
Score
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH07I038348 Enhancer 1 Ensembl ENCODE dbSUPER 550.8 -0.5 -479 3.8 CTCF MAX ELF1 NFXL1 CTBP1 IKZF1 NBN ZNF143 MYC IKZF2 TRGV5 TRGV4 TRGV5P TRGV3 ENSG00000272908 TRG-AS1 TRG
GH07I038334 Enhancer 1.6 FANTOM5 Ensembl ENCODE dbSUPER 13.3 +13.7 13681 3.7 HDGF PKNOX1 ARNT SIN3A ZNF2 POLR2B E2F8 ZNF143 ZNF263 SP3 TRGV7 ENSG00000272908 TRGV5 TRGV5P STARD3NL AMPH TRGV6 TRG
GH07I038357 Enhancer 1.1 Ensembl ENCODE dbSUPER 12.1 -9.7 -9679 3.8 CTCF RB1 BACH1 NFXL1 CC2D1A CTBP1 ZBTB48 EGR1 ZNF143 ZNF444 TRGV3 GC07P038357 GC07P038360 TRGV4 TRGV5P TRGV5 AMPH TRGV7 TRG TRG-AS1
GH07I038307 Promoter/Enhancer 1.9 FANTOM5 Ensembl ENCODE dbSUPER 5.1 +40.2 40205 4.4 HDGF ATF1 YY1 POLR2B GLIS2 ATF7 RUNX3 SP3 ZNF592 MBD2 GC07P038314 LOC103689914 TRGV9 STARD3NL TRGV5 TARP TRG
GH07I038394 Enhancer 0.5 FANTOM5 Ensembl 13.2 -44.9 -44915 1.1 CREB1 AMPH TRGV5 STARD3NL TARP TRGV1 RN7SL83P
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data dump

GeneHancers around TRGV5 on UCSC Golden Path with GeneCards custom track

Genomic Locations for TRGV5 Gene

Genomic Locations for TRGV5 Gene
chr7:38,349,355-38,350,022
(GRCh38/hg38)
Size:
668 bases
Orientation:
Minus strand
chr7:38,388,956-38,389,623
(GRCh37/hg19)

Genomic View for TRGV5 Gene

Genes around TRGV5 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
TRGV5 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for TRGV5 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for TRGV5 Gene

Proteins for TRGV5 Gene

  • Protein details for TRGV5 Gene (UniProtKB/TrEMBL)

    Protein Symbol:
    A0A0B4J1U4
    Recommended name:
    T-cell receptor gamma variable 5
    Protein Accession:
    A0A0B4J1U4

    Protein attributes for TRGV5 Gene

    Size:
    118 amino acids
    Molecular mass:
    13601 Da
    Quaternary structure:
    No Data Available

neXtProt entry for TRGV5 Gene

Post-translational modifications for TRGV5 Gene

No Post-translational modifications

Other Protein References for TRGV5 Gene

ENSEMBL proteins:

No data available for DME Specific Peptides for TRGV5 Gene

Domains & Families for TRGV5 Gene

Gene Families for TRGV5 Gene

Protein Domains for TRGV5 Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with TRGV5: view

No data available for Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for TRGV5 Gene

Function for TRGV5 Gene

Phenotypes From GWAS Catalog for TRGV5 Gene

Animal Model Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for TRGV5 Gene

Localization for TRGV5 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for TRGV5 Gene

Pathways & Interactions for TRGV5 Gene

SuperPathways for TRGV5 Gene

No Data Available

Interacting Proteins for TRGV5 Gene

Gene Ontology (GO) - Biological Process for TRGV5 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for TRGV5 Gene

Drugs & Compounds for TRGV5 Gene

No Compound Related Data Available

Transcripts for TRGV5 Gene

mRNA/cDNA for TRGV5 Gene

Clone Products

Alternative Splicing Database (ASD) splice patterns (SP) for TRGV5 Gene

No ASD Table

Relevant External Links for TRGV5 Gene

GeneLoc Exon Structure for
TRGV5
ECgene alternative splicing isoforms for
TRGV5

Expression for TRGV5 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for TRGV5 Gene

mRNA differential expression in normal tissues according to GTEx for TRGV5 Gene

This gene is overexpressed in Whole Blood (x12.1) and Spleen (x5.4).

NURSA nuclear receptor signaling pathways regulating expression of TRGV5 Gene:

TRGV5
genes like me logo Genes that share expression patterns with TRGV5: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for TRGV5 Gene

Orthologs for TRGV5 Gene

This gene was present in the common ancestor of mammals.

Orthologs for TRGV5 Gene

Organism Taxonomy Gene Similarity Type Details
cow
(Bos Taurus)
Mammalia -- 34
  • 53 (a)
OneToMany
platypus
(Ornithorhynchus anatinus)
Mammalia -- 34
  • 41 (a)
ManyToMany
-- 34
  • 40 (a)
ManyToMany
-- 34
  • 39 (a)
ManyToMany
-- 34
  • 36 (a)
ManyToMany
-- 34
  • 34 (a)
ManyToMany
-- 34
  • 32 (a)
ManyToMany
-- 34
  • 31 (a)
ManyToMany
-- 34
  • 24 (a)
ManyToMany
Species where no ortholog for TRGV5 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • chimpanzee (Pan troglodytes)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • dog (Canis familiaris)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • mouse (Mus musculus)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for TRGV5 Gene

ENSEMBL:
Gene Tree for TRGV5 (if available)
TreeFam:
Gene Tree for TRGV5 (if available)

Paralogs for TRGV5 Gene

Paralogs for TRGV5 Gene

genes like me logo Genes that share paralogs with TRGV5: view

Variants for TRGV5 Gene

Additional Variant Information for TRGV5 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
TRGV5

SNP Genotyping and Copy Number Assay Products

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Sequence variations from dbSNP and Humsavar , Structural Variations from Database of Genomic Variants (DGV) and Variation tolerance for TRGV5 Gene

Disorders for TRGV5 Gene

Additional Disease Information for TRGV5

No disorders were found for TRGV5 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for TRGV5 Gene

Publications for TRGV5 Gene

  1. The V gamma locus of the human T cell receptor gamma gene. Repertoire polymorphism of the first variable gene segment subgroup. (PMID: 2902186) Font MP … Sigaux F (The Journal of experimental medicine 1988) 2 3 58
  2. Variable region genes in the human T-cell rearranging gamma (TRG) locus: V-J junction and homology with the mouse genes. (PMID: 2969332) Huck S … Lefranc MP (The EMBO journal 1988) 2 3 58
  3. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg RL … Mammalian Gene Collection Program Team (Proceedings of the National Academy of Sciences of the United States of America 2002) 3 58
  4. The human T-cell receptor gamma (TRG) genes. (PMID: 2527426) Lefranc MP … Rabbitts TH (Trends in biochemical sciences 1989) 3 58
  5. Structure of the gamma/delta T cell receptor of a human thymocyte clone. (PMID: 2844954) Okada A … Alt FW (The Journal of experimental medicine 1988) 3 58

Products for TRGV5 Gene

Sources for TRGV5 Gene

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