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Aliases for TRGV4 Gene

Aliases for TRGV4 Gene

  • T Cell Receptor Gamma Variable 4 2 3
  • T-Cell Receptor, Gamma, Variable Region V4 2 3
  • TCRGV4 2 3
  • T-Cell Receptor Gamma Variable 4 5
  • V1S4 3

External Ids for TRGV4 Gene

Previous HGNC Symbols for TRGV4 Gene

  • TCRGV4

Previous GeneCards Identifiers for TRGV4 Gene

  • GC07U990108
  • GC07M038100
  • GC07M038134
  • GC07M038166
  • GC07M038359
  • GC07M038394
  • GC07M038430
  • GC07M038397
  • GC07M038400
  • GC07M038428
  • GC07M038675
  • GC07M038903
  • GC07M039132
  • GC07M039263
  • GC07M038435
  • GC07M038461
  • GC07M038475
  • GC07M038487
  • GC07M038500
  • GC07M038513
  • GC07M038525

Summaries for TRGV4 Gene

GeneCards Summary for TRGV4 Gene

TRGV4 (T Cell Receptor Gamma Variable 4) is a Protein Coding gene. An important paralog of this gene is TRGV2.

Additional gene information for TRGV4 Gene

No data available for Entrez Gene Summary , CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for TRGV4 Gene

Genomics for TRGV4 Gene

GeneHancer (GH) Regulatory Elements for TRGV4 Gene

Promoters and enhancers for TRGV4 Gene
GeneHancer (GH) Identifier GH Type GH
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH07I038353 Enhancer 1 Ensembl ENCODE dbSUPER 559.1 +0.7 666 1.7 SMARCA5 CTCF ZNF146 NFXL1 RAD21 CTBP1 IKZF1 ZNF444 TRGV4 GC07M038553 TRGV5P TRGV3 ENSG00000272908 TRGV5 TRG TRG-AS1
GH07I038355 Enhancer 0.4 Ensembl dbSUPER 568.7 -1.4 -1384 0.2 TRGV4 GC07M038552 GC07M038553 TRGV3 TRGV5P GC07P038357 TRG TRG-AS1
GH07I038366 Enhancer 1.2 Ensembl ENCODE dbSUPER 52.9 -14.2 -14227 4.2 HDGF RB1 NFXL1 YBX1 IRF4 RAD21 ZNF143 ATF7 BCLAF1 IKZF2 TRG TRGV1 TRGV4 TRGV5P TRGV3 AMPH TRG-AS1 RN7SL83P
GH07I038357 Enhancer 1.1 Ensembl ENCODE dbSUPER 48.7 -5.2 -5184 3.8 CTCF RB1 BACH1 NFXL1 CC2D1A CTBP1 ZBTB48 EGR1 ZNF143 ZNF444 TRGV3 GC07P038357 GC07P038360 TRGV4 TRGV5P TRGV5 AMPH TRGV7 TRG TRG-AS1
GH07I038340 Enhancer 1.3 Ensembl ENCODE dbSUPER 39.7 +12.9 12946 3.3 HDGF PKNOX1 ATF1 ARNT POLR2B E2F8 ARID2 ATF7 ZNF263 NCOA1 TRG-AS1 TRGV6 TRGV4 TRGV3 TRGV5P TRG
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data dump

GeneHancers around TRGV4 on UCSC Golden Path with GeneCards custom track

Genomic Locations for TRGV4 Gene

Genomic Locations for TRGV4 Gene
803 bases
Minus strand

Genomic View for TRGV4 Gene

Genes around TRGV4 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
TRGV4 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for TRGV4 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for TRGV4 Gene

Proteins for TRGV4 Gene

  • Protein details for TRGV4 Gene (UniProtKB/TrEMBL)

    Protein Symbol:
    Recommended name:
    T-cell receptor gamma variable 4
    Protein Accession:

    Protein attributes for TRGV4 Gene

    118 amino acids
    Molecular mass:
    13152 Da
    Quaternary structure:
    No Data Available

neXtProt entry for TRGV4 Gene

Post-translational modifications for TRGV4 Gene

No Post-translational modifications

Other Protein References for TRGV4 Gene

ENSEMBL proteins:

No data available for DME Specific Peptides for TRGV4 Gene

Domains & Families for TRGV4 Gene

Gene Families for TRGV4 Gene

Protein Domains for TRGV4 Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with TRGV4: view

No data available for Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for TRGV4 Gene

Function for TRGV4 Gene

Phenotypes From GWAS Catalog for TRGV4 Gene

Animal Model Products

Clone Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for TRGV4 Gene

Localization for TRGV4 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for TRGV4 Gene

Pathways & Interactions for TRGV4 Gene

SuperPathways for TRGV4 Gene

No Data Available

Interacting Proteins for TRGV4 Gene

Gene Ontology (GO) - Biological Process for TRGV4 Gene


No data available for Pathways by source and SIGNOR curated interactions for TRGV4 Gene

Drugs & Compounds for TRGV4 Gene

No Compound Related Data Available

Transcripts for TRGV4 Gene

mRNA/cDNA for TRGV4 Gene

Clone Products

Alternative Splicing Database (ASD) splice patterns (SP) for TRGV4 Gene

No ASD Table

Relevant External Links for TRGV4 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for TRGV4 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for TRGV4 Gene

mRNA differential expression in normal tissues according to GTEx for TRGV4 Gene

This gene is overexpressed in Whole Blood (x12.0) and Spleen (x8.4).

NURSA nuclear receptor signaling pathways regulating expression of TRGV4 Gene:

genes like me logo Genes that share expression patterns with TRGV4: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for TRGV4 Gene

Orthologs for TRGV4 Gene

This gene was present in the common ancestor of mammals.

Orthologs for TRGV4 Gene

Organism Taxonomy Gene Similarity Type Details
(Bos Taurus)
Mammalia -- 34
  • 54 (a)
(Ornithorhynchus anatinus)
Mammalia -- 34
  • 41 (a)
-- 34
  • 40 (a)
-- 34
  • 40 (a)
-- 34
  • 35 (a)
-- 34
  • 35 (a)
-- 34
  • 34 (a)
-- 34
  • 32 (a)
-- 34
  • 23 (a)
Species where no ortholog for TRGV4 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • chimpanzee (Pan troglodytes)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • dog (Canis familiaris)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • mouse (Mus musculus)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for TRGV4 Gene

Gene Tree for TRGV4 (if available)
Gene Tree for TRGV4 (if available)

Paralogs for TRGV4 Gene

Paralogs for TRGV4 Gene

genes like me logo Genes that share paralogs with TRGV4: view

Variants for TRGV4 Gene

Additional Variant Information for TRGV4 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Sequence variations from dbSNP and Humsavar , Structural Variations from Database of Genomic Variants (DGV) and Variation tolerance for TRGV4 Gene

Disorders for TRGV4 Gene

No disorders were found for TRGV4 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot , Genatlas and External Links for TRGV4 Gene

Publications for TRGV4 Gene

  1. Variable region genes in the human T-cell rearranging gamma (TRG) locus: V-J junction and homology with the mouse genes. (PMID: 2969332) Huck S … Lefranc MP (The EMBO journal 1988) 2 3 58
  2. The human T-cell receptor gamma (TRG) genes. (PMID: 2527426) Lefranc MP … Rabbitts TH (Trends in biochemical sciences 1989) 3 58

Products for TRGV4 Gene

Sources for TRGV4 Gene

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