Aliases for TRERNA1 Gene

Subcategory (RNA class) for TRERNA1 Gene

lncRNA

Number of RNA Genes sources:

3 / 14

Aliases for TRERNA1 Gene

  • Translation Regulatory Long Non-Coding RNA 1 2 3 5
  • Translational Regulatory Long Non-Coding RNA 2 3
  • Long Intergenic Non-Protein Coding RNA 651 2 3
  • TRERNA1 2 168
  • Noncoding RNA-Activating 7 3
  • NONHSAG031991 92
  • HSALNG0130723 167
  • LINC00651 3
  • NcRNA-A7 3
  • TreRNA 3

External Ids for TRERNA1 Gene

Previous HGNC Symbols for TRERNA1 Gene

  • LINC00651

Previous GeneCards Identifiers for TRERNA1 Gene

  • GC20M048659

Summaries for TRERNA1 Gene

GeneCards Summary for TRERNA1 Gene

TRERNA1 (Translation Regulatory Long Non-Coding RNA 1) is an RNA Gene, and is affiliated with the lncRNA class. Diseases associated with TRERNA1 include Leukemia, Chronic Lymphocytic and Gastric Cancer.

Additional gene information for TRERNA1 Gene

No data available for Entrez Gene Summary , CIViC Summary , UniProtKB/Swiss-Prot Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , Rfam classification and piRNA Summary for TRERNA1 Gene

Genomics for TRERNA1 Gene

GeneHancer (GH) Regulatory Elements for TRERNA1 Gene

Promoters and enhancers for TRERNA1 Gene
GeneHancer (GH) Identifier GH Type GH
Score
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH20J050038 Enhancer 1.2 Ensembl ENCODE CraniofacialAtlas 500.7 +1.0 1028 4.4 ZNF217 ZIC2 CUX1 CHD1 ZBTB7A GATAD2B CTBP1 RBM25 PCBP1 SIN3A TRERNA1 RNF114 SNAI1 SPATA2 HSALNG0130724 lnc-TMEM189-UBE2V1-5
GH20J050032 Enhancer 1 ENCODE dbSUPER 5.1 +7.4 7448 2.5 NCOR1 FOS ZIC2 POLR2A RFX1 EP300 SKI TEAD1 NR2F2 CREB1 lnc-TMEM189-UBE2V1-5 SPATA2 TRERNA1 lnc-SNAI1-5
GH20J050037 Enhancer 0.5 ENCODE 0.7 +4.1 4110 0.2 ZNF217 RBM25 PTBP1 DPF2 RCOR1 VEZF1 CEBPG KDM1A HDAC2 TRERNA1 lnc-TMEM189-UBE2V1-5
GH20J050041 Enhancer 0.5 Ensembl 0.7 +3.5 3528 0.2 ZNF623 PTBP1 HDAC2 ZBTB1 ZMYM3 VEZF1 KDM1A RLF ZNF121 TRERNA1 lnc-TMEM189-UBE2V1-5
GH20J050040 Enhancer 0.4 Ensembl 0.7 +4.3 4328 0.2 ZNF217 DPF2 RCOR1 CEBPG CEBPB TRERNA1 lnc-TMEM189-UBE2V1-5
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data from 2017 publication | Request up-to-date GeneHancer data (full dataset)

GeneHancers around TRERNA1 on UCSC Golden Path with GeneCards custom track

Genomic Locations for TRERNA1 Gene

Genomic Locations for TRERNA1 Gene
chr20:50,040,706-50,041,629
(GRCh38/hg38)
Size:
924 bases
Orientation:
Minus strand
chr20:48,657,253-48,658,041
(GRCh37/hg19)
Size:
789 bases
Orientation:
Minus strand

Genomic View for TRERNA1 Gene

Genes around TRERNA1 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
TRERNA1 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for TRERNA1 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for TRERNA1 Gene

Proteins for TRERNA1 Gene

Post-translational modifications for TRERNA1 Gene

No Post-translational modifications

No data available for DME Specific Peptides for TRERNA1 Gene

Domains & Families for TRERNA1 Gene

Gene Families for TRERNA1 Gene

genes like me logo Genes that share domains with TRERNA1: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences , Graphical View of Domain Structure and UniProtKB/Swiss-Prot for TRERNA1 Gene

Function for TRERNA1 Gene

Phenotypes From GWAS Catalog for TRERNA1 Gene

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for TRERNA1 Gene

Localization for TRERNA1 Gene

Subcellular locations from

COMPARTMENTS
Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for TRERNA1 gene
Compartment Confidence
plasma membrane 1
extracellular 1
cytoskeleton 1
nucleus 1

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for TRERNA1 Gene

Pathways & Interactions for TRERNA1 Gene

PathCards logo

SuperPathways for TRERNA1 Gene

No Data Available
;

Gene Ontology (GO) - Biological Process for TRERNA1 Gene

None

No data available for Pathways by source , Interacting Proteins and SIGNOR curated interactions for TRERNA1 Gene

Drugs & Compounds for TRERNA1 Gene

No Compound Related Data Available

Transcripts for TRERNA1 Gene

mRNA/cDNA for TRERNA1 Gene

4 RNACentral transcripts :
1 REFSEQ mRNAs :
4 NCBI additional mRNA sequence :
1 Ensembl transcripts including schematic representations, and UCSC links to gene/alias where relevant :
1 NONCODE transcripts :
2 LncBook transcripts :
2 LNCipedia transcripts :

Alternative Splicing Database (ASD) splice patterns (SP) for TRERNA1 Gene

No ASD Table

Relevant External Links for TRERNA1 Gene

GeneLoc Exon Structure for
TRERNA1

Expression for TRERNA1 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and SAGE for TRERNA1 Gene

mRNA differential expression in normal tissues according to GTEx for TRERNA1 Gene

This gene is overexpressed in Testis (x19.6), Whole Blood (x12.7), Spleen (x9.0), Small Intestine - Terminal Ileum (x4.2), and Cervix - Endocervix (x4.1).

Transcriptomic regulation report from SPP (The Signaling Pathways Project) for TRERNA1

genes like me logo Genes that share expression patterns with TRERNA1: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for TRERNA1 Gene

Orthologs for TRERNA1 Gene

Evolution for TRERNA1 Gene

ENSEMBL:
Gene Tree for TRERNA1 (if available)
TreeFam:
Gene Tree for TRERNA1 (if available)

No data available for Orthologs for TRERNA1 Gene

Paralogs for TRERNA1 Gene

No data available for Paralogs for TRERNA1 Gene

Variants for TRERNA1 Gene

Additional dbSNP identifiers (rs#s) for TRERNA1 Gene

Structural Variations from Database of Genomic Variants (DGV) for TRERNA1 Gene

Variant ID Type Subtype PubMed ID
nsv3413 CNV insertion 18451855
nsv509776 CNV insertion 20534489
nsv833999 CNV loss 17160897
nsv834000 CNV gain+loss 17160897

Additional Variant Information for TRERNA1 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
TRERNA1

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Sequence variations, with clinical significance, from ClinVar and Humsavar, with links to dbSNP and Variation tolerance for TRERNA1 Gene

Disorders for TRERNA1 Gene

MalaCards: The human disease database

(3) MalaCards diseases for TRERNA1 Gene - From: LncRNADisease and DISEASES

Disorder Aliases PubMed IDs
leukemia, chronic lymphocytic
  • cll
gastric cancer
  • gastric cancer, somatic
opitz-kaveggia syndrome
  • oks
- elite association - COSMIC cancer census association via MalaCards

Additional Disease Information for TRERNA1

genes like me logo Genes that share disorders with TRERNA1: view

No data available for UniProtKB/Swiss-Prot and Genatlas for TRERNA1 Gene

Publications for TRERNA1 Gene

  1. Identification of a long non-coding RNA-associated RNP complex regulating metastasis at the translational step. (PMID: 23974796) Gumireddy K … Huang Q (The EMBO journal 2013) 2 3 54
  2. Long noncoding RNAs with enhancer-like function in human cells. (PMID: 20887892) Ørom UA … Shiekhattar R (Cell 2010) 2 3 54
  3. LncRNA TRERNA1 facilitates hepatocellular carcinoma metastasis by dimethylating H3K9 in the CDH1 promoter region via the recruitment of the EHMT2/SNAI1 complex. (PMID: 31012192) Song W … Fan H (Cell proliferation 2019) 3 54
  4. Elevated TFAP4 regulates lncRNA TRERNA1 to promote cell migration and invasion in gastric cancer. (PMID: 29845218) Wu H … Fan H (Oncology reports 2018) 3 54
  5. The long noncoding RNA, treRNA, decreases DNA damage and is associated with poor response to chemotherapy in chronic lymphocytic leukemia. (PMID: 28412730) Miller CR … Hertlein EK (Oncotarget 2017) 3 54

Products for TRERNA1 Gene

Sources for TRERNA1 Gene