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Aliases for TRDV1 Gene

Aliases for TRDV1 Gene

  • T Cell Receptor Delta Variable 1 2 3
  • T-Cell Receptor Delta Variable 1 5
  • HDV101S1 3

External Ids for TRDV1 Gene

Previous GeneCards Identifiers for TRDV1 Gene

  • GC14U990268
  • GC14P020554
  • GC14P021634
  • GC14P022565
  • GC14P022572
  • GC14P022604
  • GC14P022721
  • GC14P022830

Summaries for TRDV1 Gene

Entrez Gene Summary for TRDV1 Gene

  • T cell receptors recognize foreign antigens which have been processed as small peptides and bound to major histocompatibility complex (MHC) molecules at the surface of antigen presenting cells (APC). Each T cell receptor is a dimer consisting of one alpha and one beta chain or one delta and one gamma chain. In a single cell, the T cell receptor loci are rearranged and expressed in the order delta, gamma, beta, and alpha. If both delta and gamma rearrangements produce functional chains, the cell expresses delta and gamma. If not, the cell proceeds to rearrange the beta and alpha loci. This region represents the germline organization of the T cell receptor alpha and delta loci. Both the alpha and delta loci include V (variable), J (joining), and C (constant) segments and the delta locus also includes diversity (D) segments. The delta locus is situated within the alpha locus, between the alpha V and J segments. During T cell development, the delta chain is synthesized by a recombination event at the DNA level joining a D segment with a J segment; a V segment is then joined to the D-J gene. The alpha chain is synthesized by recombination joining a single V segment with a J segment. For both chains, the C segment is later joined by splicing at the RNA level. Recombination of many different V segments with several J segments provides a wide range of antigen recognition. Additional diversity is attained by junctional diversity, resulting from the random additional of nucleotides by terminal deoxynucleotidyltransferase. Five variable segments can be used in either alpha or delta chains and are described by TRAV/DV symbols. Several V and J segments of the alpha locus are known to be incapable of encoding a protein and are considered pseudogenes. [provided by RefSeq, Aug 2016]

GeneCards Summary for TRDV1 Gene

TRDV1 (T Cell Receptor Delta Variable 1) is a Protein Coding gene. An important paralog of this gene is TRAV14DV4.

Additional gene information for TRDV1 Gene

No data available for CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for TRDV1 Gene

Genomics for TRDV1 Gene

GeneHancer (GH) Regulatory Elements for TRDV1 Gene

Promoters and enhancers for TRDV1 Gene
GeneHancer (GH) Identifier GH Type GH
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH14I022095 Enhancer 0.9 Ensembl ENCODE dbSUPER 550.8 +1.0 1042 3.2 ZBED1 ZFP64 FOXP2 MNT RFX5 ZNF7 TRDV1 TRAV24 TRA
GH14I022100 Enhancer 0.8 ENCODE 0.8 +4.4 4377 0.2 ELF3 ARID4B ZNF48 ZSCAN9 RAD21 ZNF143 THAP11 MIXL1 SMARCA5 MXD4 TRAV24 TRDV1 TRA
GH14I022104 Enhancer 0.4 ENCODE dbSUPER 0.4 +9.1 9149 1.1 TRAV24 RBM23 TRAV8-4 TRDV1 TRA
GH14I022085 Enhancer 0.2 dbSUPER 0.4 -9.6 -9550 1.3 TRAV23DV6 TRDV1 TRA
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data dump

GeneHancers around TRDV1 on UCSC Golden Path with GeneCards custom track

Genomic Locations for TRDV1 Gene

Genomic Locations for TRDV1 Gene
588 bases
Plus strand

Genomic View for TRDV1 Gene

Genes around TRDV1 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
TRDV1 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for TRDV1 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for TRDV1 Gene

Proteins for TRDV1 Gene

  • Protein details for TRDV1 Gene (UniProtKB/TrEMBL)

    Protein Symbol:
    Recommended name:
    T-cell receptor delta variable 1
    Protein Accession:

    Protein attributes for TRDV1 Gene

    34 amino acids
    Molecular mass:
    3696 Da
    Quaternary structure:
    No Data Available
  • Protein details for TRDV1 Gene (UniProtKB/TrEMBL)

    Protein Symbol:
    Recommended name:
    T-cell receptor delta variable 1
    Protein Accession:

    Protein attributes for TRDV1 Gene

    115 amino acids
    Molecular mass:
    12955 Da
    Quaternary structure:
    No Data Available

neXtProt entry for TRDV1 Gene

Post-translational modifications for TRDV1 Gene

No Post-translational modifications

Other Protein References for TRDV1 Gene

ENSEMBL proteins:

No data available for DME Specific Peptides for TRDV1 Gene

Domains & Families for TRDV1 Gene

Gene Families for TRDV1 Gene

Protein Domains for TRDV1 Gene

Suggested Antigen Peptide Sequences for TRDV1 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with TRDV1: view

No data available for UniProtKB/Swiss-Prot for TRDV1 Gene

Function for TRDV1 Gene

Animal Model Products

Clone Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes From GWAS Catalog , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for TRDV1 Gene

Localization for TRDV1 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for TRDV1 Gene

Pathways & Interactions for TRDV1 Gene

SuperPathways for TRDV1 Gene

No Data Available

Interacting Proteins for TRDV1 Gene

Gene Ontology (GO) - Biological Process for TRDV1 Gene


No data available for Pathways by source and SIGNOR curated interactions for TRDV1 Gene

Drugs & Compounds for TRDV1 Gene

No Compound Related Data Available

Transcripts for TRDV1 Gene

mRNA/cDNA for TRDV1 Gene

(37) Additional mRNA sequences :
(5) Selected AceView cDNA sequences:
(2) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for TRDV1 Gene

T cell receptor delta variable 1:
Representative Sequences:

Clone Products

Alternative Splicing Database (ASD) splice patterns (SP) for TRDV1 Gene

No ASD Table

Relevant External Links for TRDV1 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for TRDV1 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for TRDV1 Gene

mRNA differential expression in normal tissues according to GTEx for TRDV1 Gene

This gene is overexpressed in Whole Blood (x29.1) and Spleen (x10.3).

NURSA nuclear receptor signaling pathways regulating expression of TRDV1 Gene:


SOURCE GeneReport for Unigene cluster for TRDV1 Gene:

genes like me logo Genes that share expression patterns with TRDV1: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for TRDV1 Gene

Orthologs for TRDV1 Gene

This gene was present in the common ancestor of mammals.

Orthologs for TRDV1 Gene

Organism Taxonomy Gene Similarity Type Details
(Bos Taurus)
Mammalia -- 34
  • 68 (a)
-- 34
  • 53 (a)
(Mus musculus)
Mammalia Trav15-2-dv6-2 34
  • 54 (a)
Trav15d-1-dv6d-1 34
  • 51 (a)
(Canis familiaris)
Mammalia TRDV1 34
  • 52 (a)
(Monodelphis domestica)
Mammalia TRDV1 34
  • 52 (a)
(Ornithorhynchus anatinus)
Mammalia -- 34
  • 46 (a)
-- 34
  • 45 (a)
-- 34
  • 45 (a)
-- 34
  • 45 (a)
-- 34
  • 44 (a)
-- 34
  • 44 (a)
-- 34
  • 44 (a)
-- 34
  • 41 (a)
-- 34
  • 34 (a)
-- 34
  • 32 (a)
Species where no ortholog for TRDV1 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • chimpanzee (Pan troglodytes)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for TRDV1 Gene

Gene Tree for TRDV1 (if available)
Gene Tree for TRDV1 (if available)

Paralogs for TRDV1 Gene

Paralogs for TRDV1 Gene Pseudogenes for TRDV1 Gene

genes like me logo Genes that share paralogs with TRDV1: view

Variants for TRDV1 Gene

Additional Variant Information for TRDV1 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Sequence variations from dbSNP and Humsavar , Structural Variations from Database of Genomic Variants (DGV) and Variation tolerance for TRDV1 Gene

Disorders for TRDV1 Gene

Additional Disease Information for TRDV1

No disorders were found for TRDV1 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for TRDV1 Gene

Publications for TRDV1 Gene

  1. Genomic organization of the human T-cell antigen-receptor alpha/delta locus. (PMID: 3186718) Satyanarayana K … Krangel MS (Proceedings of the National Academy of Sciences of the United States of America 1988) 2 3 58
  2. The TCR-delta repertoire in human intestine undergoes characteristic changes during fetal to adult development. (PMID: 9190911) Holtmeier W … Kagnoff MF (Journal of immunology (Baltimore, Md. : 1950) 1997) 3 58
  3. Sequence and evolution of the human germline V lambda repertoire. (PMID: 8951372) Williams SC … Winter G (Journal of molecular biology 1996) 3 58

Products for TRDV1 Gene

Sources for TRDV1 Gene

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