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Aliases for TRBV5-4 Gene

Aliases for TRBV5-4 Gene

  • T Cell Receptor Beta Variable 5-4 2 3
  • T-Cell Receptor Beta Variable 5-4 5
  • V_segment Translation Product 3
  • TCRBV5S6A3N2T 3
  • TCRBV5S4 3
  • TRBV54 3

External Ids for TRBV5-4 Gene

Previous GeneCards Identifiers for TRBV5-4 Gene

  • GC07U990234
  • GC07P141515
  • GC07P141593
  • GC07P141596
  • GC07P141639
  • GC07P141833
  • GC07P141835
  • GC07P141840
  • GC07P141951
  • GC07M142168
  • GC07P142685
  • GC07P142954
  • GC07P143099
  • GC07P143254
  • GC07P143450
  • GC07P143595
  • GC07P143737

Summaries for TRBV5-4 Gene

GeneCards Summary for TRBV5-4 Gene

TRBV5-4 (T Cell Receptor Beta Variable 5-4) is a Protein Coding gene. An important paralog of this gene is TRBV5-6.

Additional gene information for TRBV5-4 Gene

No data available for Entrez Gene Summary , CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for TRBV5-4 Gene

Genomics for TRBV5-4 Gene

GeneHancer (GH) Regulatory Elements for TRBV5-4 Gene

Promoters and enhancers for TRBV5-4 Gene
GeneHancer (GH) Identifier GH Type GH
Score
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH07I142462 Enhancer 0.2 Ensembl 550.8 +0.4 385 1 TRBV5-4 TRBV6-6 TRB
GH07I142459 Enhancer 0.2 Ensembl 0.8 -2.9 -2915 1.2 TRBV5-4 TRBV7-4 TRB
GH07I142455 Enhancer 0.2 Ensembl 0.4 -7.4 -7415 0.2 TRBV7-4 TRBV5-4 TRB
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data dump

GeneHancers around TRBV5-4 on UCSC Golden Path with GeneCards custom track

Genomic Locations for TRBV5-4 Gene

Genomic Locations for TRBV5-4 Gene
chr7:142,462,916-142,463,581
(GRCh38/hg38)
Size:
666 bases
Orientation:
Plus strand
chr7:142,168,380-142,169,045
(GRCh37/hg19)

Genomic View for TRBV5-4 Gene

Genes around TRBV5-4 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
TRBV5-4 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for TRBV5-4 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for TRBV5-4 Gene

Proteins for TRBV5-4 Gene

  • Protein details for TRBV5-4 Gene (UniProtKB/TrEMBL)

    Protein Symbol:
    A0A0C4DH59
    Recommended name:
    T-cell receptor beta variable 5-4
    Protein Accession:
    A0A0C4DH59

    Protein attributes for TRBV5-4 Gene

    Size:
    114 amino acids
    Molecular mass:
    12518 Da
    Quaternary structure:
    No Data Available
  • Protein details for TRBV5-4 Gene (UniProtKB/TrEMBL)

    Protein Symbol:
    A0A0J9YXE9
    Recommended name:
    T-cell receptor beta variable 5-4
    Protein Accession:
    A0A0J9YXE9

    Protein attributes for TRBV5-4 Gene

    Size:
    114 amino acids
    Molecular mass:
    12426 Da
    Quaternary structure:
    No Data Available

neXtProt entry for TRBV5-4 Gene

Post-translational modifications for TRBV5-4 Gene

No Post-translational modifications

Other Protein References for TRBV5-4 Gene

ENSEMBL proteins:

No data available for DME Specific Peptides for TRBV5-4 Gene

Domains & Families for TRBV5-4 Gene

Gene Families for TRBV5-4 Gene

Protein Domains for TRBV5-4 Gene

Suggested Antigen Peptide Sequences for TRBV5-4 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with TRBV5-4: view

No data available for UniProtKB/Swiss-Prot for TRBV5-4 Gene

Function for TRBV5-4 Gene

Clone Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes From GWAS Catalog , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for TRBV5-4 Gene

Localization for TRBV5-4 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for TRBV5-4 Gene

Pathways & Interactions for TRBV5-4 Gene

SuperPathways for TRBV5-4 Gene

No Data Available

Interacting Proteins for TRBV5-4 Gene

Gene Ontology (GO) - Biological Process for TRBV5-4 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for TRBV5-4 Gene

Drugs & Compounds for TRBV5-4 Gene

No Compound Related Data Available

Transcripts for TRBV5-4 Gene

mRNA/cDNA for TRBV5-4 Gene

Clone Products

Alternative Splicing Database (ASD) splice patterns (SP) for TRBV5-4 Gene

No ASD Table

Relevant External Links for TRBV5-4 Gene

GeneLoc Exon Structure for
TRBV5-4
ECgene alternative splicing isoforms for
TRBV5-4

Expression for TRBV5-4 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for TRBV5-4 Gene

mRNA differential expression in normal tissues according to GTEx for TRBV5-4 Gene

This gene is overexpressed in Whole Blood (x24.8) and Pancreas (x8.7).

Integrated Proteomics: protein expression in normal tissues and cell lines from MaxQB and MOPED for TRBV5-4 Gene



genes like me logo Genes that share expression patterns with TRBV5-4: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , Protein differential expression in normal tissues , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for TRBV5-4 Gene

Orthologs for TRBV5-4 Gene

This gene was present in the common ancestor of mammals.

Orthologs for TRBV5-4 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia TRBV5-4 34
  • 79 (a)
OneToOne
oppossum
(Monodelphis domestica)
Mammalia -- 34
  • 47 (a)
ManyToMany
-- 34
  • 45 (a)
ManyToMany
platypus
(Ornithorhynchus anatinus)
Mammalia -- 34
  • 40 (a)
OneToMany
Species where no ortholog for TRBV5-4 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • cow (Bos Taurus)
  • dog (Canis familiaris)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • mouse (Mus musculus)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for TRBV5-4 Gene

ENSEMBL:
Gene Tree for TRBV5-4 (if available)
TreeFam:
Gene Tree for TRBV5-4 (if available)

Paralogs for TRBV5-4 Gene

Paralogs for TRBV5-4 Gene

genes like me logo Genes that share paralogs with TRBV5-4: view

Variants for TRBV5-4 Gene

Additional Variant Information for TRBV5-4 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
TRBV5-4

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Sequence variations from dbSNP and Humsavar , Structural Variations from Database of Genomic Variants (DGV) and Variation tolerance for TRBV5-4 Gene

Disorders for TRBV5-4 Gene

Additional Disease Information for TRBV5-4

No disorders were found for TRBV5-4 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for TRBV5-4 Gene

Publications for TRBV5-4 Gene

  1. The complete 685-kilobase DNA sequence of the human beta T cell receptor locus. (PMID: 8650574) Rowen L … Hood L (Science (New York, N.Y.) 1996) 2 3 58
  2. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg RL … Mammalian Gene Collection Program Team (Proceedings of the National Academy of Sciences of the United States of America 2002) 3 58
  3. Nucleotide sequence analysis of 77.7 kb of the human V beta T-cell receptor gene locus: direct primer-walking using cosmid template DNAs. (PMID: 8020962) Slightom JL … Hood L (Genomics 1994) 3 58

Products for TRBV5-4 Gene

Sources for TRBV5-4 Gene

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