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Aliases for TRBV4-1 Gene

Aliases for TRBV4-1 Gene

  • T Cell Receptor Beta Variable 4-1 2 3
  • T-Cell Receptor Beta Chain V Region 86T1 3
  • T-Cell Receptor Beta Variable 4-1 5
  • V_segment Translation Product 3
  • TCRBV7S1A1N2T 3
  • BV07S1J2.7 3
  • TCRBV4S1 3
  • TRBV41 3

External Ids for TRBV4-1 Gene

Previous GeneCards Identifiers for TRBV4-1 Gene

  • GC07U990240
  • GC07P141343
  • GC07P141420
  • GC07P141471
  • GC07P141659
  • GC07P142162
  • GC07P142184
  • GC07P142318
  • GC07P142357
  • GC07P142408
  • GC07P142455
  • GC07P142581
  • GC07P142672
  • GC07P142740
  • GC07P142802
  • GC07P142601
  • GC07P142833
  • GC07P142994
  • GC07P143146
  • GC07P143346
  • GC07P143491
  • GC07P143626

Summaries for TRBV4-1 Gene

GeneCards Summary for TRBV4-1 Gene

TRBV4-1 (T Cell Receptor Beta Variable 4-1) is a Protein Coding gene. An important paralog of this gene is TRBV4-2.

Additional gene information for TRBV4-1 Gene

No data available for Entrez Gene Summary , CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for TRBV4-1 Gene

Genomics for TRBV4-1 Gene

GeneHancer (GH) Regulatory Elements for TRBV4-1 Gene

Promoters and enhancers for TRBV4-1 Gene
GeneHancer (GH) Identifier GH Type GH
Score
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH07I142312 Enhancer 0.6 Ensembl ENCODE dbSUPER 567.5 +0.6 566 2.5 TRBV4-1 TRBV5-1 TRB
GH07I142313 Enhancer 0.4 ENCODE dbSUPER 550.8 -0.7 -711 0 TRBV4-1 TRBV3-1 TRB
GH07I142321 Enhancer 0.7 ENCODE dbSUPER 5.9 +7.0 7003 0.2 CTCF ZNF3 ZNF316 ZNF143 MAFK TRBV5-1 TRBV4-1 TRB
GH07I142302 Enhancer 0.3 dbSUPER 12.9 -10.3 -10262 1.1 CTCF TRBV2 TRBV4-1 TRY2P TRB TRBV3-1
GH07I142320 Enhancer 0.4 Ensembl dbSUPER 4.8 +7.8 7817 0.4 TRBV5-1 TRBV4-1 TRBV6-1 TRB
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data dump

GeneHancers around TRBV4-1 on UCSC Golden Path with GeneCards custom track

Genomic Locations for TRBV4-1 Gene

Genomic Locations for TRBV4-1 Gene
chr7:142,313,184-142,313,666
(GRCh38/hg38)
Size:
483 bases
Orientation:
Plus strand
chr7:142,013,007-142,013,489
(GRCh37/hg19)

Genomic View for TRBV4-1 Gene

Genes around TRBV4-1 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
TRBV4-1 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for TRBV4-1 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for TRBV4-1 Gene

Proteins for TRBV4-1 Gene

  • Protein details for TRBV4-1 Gene (UniProtKB/TrEMBL)

    Protein Symbol:
    A0A0J9YWV2
    Recommended name:
    T-cell receptor beta variable 4-1
    Protein Accession:
    A0A0J9YWV2

    Protein attributes for TRBV4-1 Gene

    Size:
    114 amino acids
    Molecular mass:
    12918 Da
    Quaternary structure:
    No Data Available
  • Protein details for TRBV4-1 Gene (UniProtKB/TrEMBL)

    Protein Symbol:
    A0A577
    Recommended name:
    T-cell receptor beta variable 4-1
    Protein Accession:
    A0A577
    Secondary Accessions:
    • A0A075B6L4

    Protein attributes for TRBV4-1 Gene

    Size:
    114 amino acids
    Molecular mass:
    12859 Da
    Quaternary structure:
    No Data Available

neXtProt entry for TRBV4-1 Gene

Post-translational modifications for TRBV4-1 Gene

No Post-translational modifications

Other Protein References for TRBV4-1 Gene

ENSEMBL proteins:

No data available for DME Specific Peptides for TRBV4-1 Gene

Domains & Families for TRBV4-1 Gene

Gene Families for TRBV4-1 Gene

Protein Domains for TRBV4-1 Gene

Suggested Antigen Peptide Sequences for TRBV4-1 Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with TRBV4-1: view

No data available for UniProtKB/Swiss-Prot for TRBV4-1 Gene

Function for TRBV4-1 Gene

Animal Model Products

Clone Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes From GWAS Catalog , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for TRBV4-1 Gene

Localization for TRBV4-1 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for TRBV4-1 Gene

Pathways & Interactions for TRBV4-1 Gene

SuperPathways for TRBV4-1 Gene

No Data Available

Interacting Proteins for TRBV4-1 Gene

Gene Ontology (GO) - Biological Process for TRBV4-1 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for TRBV4-1 Gene

Drugs & Compounds for TRBV4-1 Gene

No Compound Related Data Available

Transcripts for TRBV4-1 Gene

mRNA/cDNA for TRBV4-1 Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Clone Products

Alternative Splicing Database (ASD) splice patterns (SP) for TRBV4-1 Gene

No ASD Table

Relevant External Links for TRBV4-1 Gene

GeneLoc Exon Structure for
TRBV4-1
ECgene alternative splicing isoforms for
TRBV4-1

Expression for TRBV4-1 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for TRBV4-1 Gene

mRNA differential expression in normal tissues according to GTEx for TRBV4-1 Gene

This gene is overexpressed in Whole Blood (x30.7) and Spleen (x6.0).
genes like me logo Genes that share expression patterns with TRBV4-1: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for TRBV4-1 Gene

Orthologs for TRBV4-1 Gene

This gene was present in the common ancestor of chordates.

Orthologs for TRBV4-1 Gene

Organism Taxonomy Gene Similarity Type Details
cow
(Bos Taurus)
Mammalia -- 34
  • 57 (a)
OneToMany
dog
(Canis familiaris)
Mammalia -- 34
  • 57 (a)
OneToMany
platypus
(Ornithorhynchus anatinus)
Mammalia -- 34
  • 41 (a)
OneToMany
oppossum
(Monodelphis domestica)
Mammalia -- 34
  • 40 (a)
OneToMany
chicken
(Gallus gallus)
Aves -- 34
  • 26 (a)
ManyToMany
-- 34
  • 20 (a)
ManyToMany
-- 34
  • 19 (a)
ManyToMany
lizard
(Anolis carolinensis)
Reptilia -- 34
  • 29 (a)
ManyToMany
-- 34
  • 23 (a)
ManyToMany
Species where no ortholog for TRBV4-1 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chimpanzee (Pan troglodytes)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • mouse (Mus musculus)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for TRBV4-1 Gene

ENSEMBL:
Gene Tree for TRBV4-1 (if available)
TreeFam:
Gene Tree for TRBV4-1 (if available)

Paralogs for TRBV4-1 Gene

Paralogs for TRBV4-1 Gene

genes like me logo Genes that share paralogs with TRBV4-1: view

Variants for TRBV4-1 Gene

Additional Variant Information for TRBV4-1 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
TRBV4-1

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Sequence variations from dbSNP and Humsavar , Structural Variations from Database of Genomic Variants (DGV) and Variation tolerance for TRBV4-1 Gene

Disorders for TRBV4-1 Gene

No disorders were found for TRBV4-1 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot , Genatlas and External Links for TRBV4-1 Gene

Publications for TRBV4-1 Gene

  1. The complete 685-kilobase DNA sequence of the human beta T cell receptor locus. (PMID: 8650574) Rowen L … Hood L (Science (New York, N.Y.) 1996) 2 3 58
  2. In angioimmunoblastic T-cell lymphoma, neoplastic T cells may be a minor cell population. A molecular single-cell and immunohistochemical study. (PMID: 15480765) Willenbrock K … Hansmann ML (Virchows Archiv : an international journal of pathology 2005) 3 58
  3. A genetically determined insertion/deletion related polymorphism in human T cell receptor beta chain (TCRB) includes functional variable gene segments. (PMID: 7931073) Zhao TM … Robinson MA (The Journal of experimental medicine 1994) 3 58

Products for TRBV4-1 Gene

Sources for TRBV4-1 Gene

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