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Aliases for TRBV28 Gene

Aliases for TRBV28 Gene

  • T Cell Receptor Beta Variable 28 2 3 5
  • V_segment Translation Product 3 12
  • TCRBV3S1 3 12
  • TCRBV28S1 3

External Ids for TRBV28 Gene

Previous GeneCards Identifiers for TRBV28 Gene

  • GC07U990182
  • GC07P141792
  • GC07P141868
  • GC07P141914
  • GC07P142108
  • GC07P142429
  • GC07P142453
  • GC07P142492
  • GC07P142649
  • GC07P142719
  • GC07P142779
  • GC07P142843
  • GC07P142892
  • GC07P143022
  • GC07P143171
  • GC07P143369
  • GC07P143519
  • GC07P143650
  • GC07P143789

Summaries for TRBV28 Gene

GeneCards Summary for TRBV28 Gene

TRBV28 (T Cell Receptor Beta Variable 28) is a Protein Coding gene. An important paralog of this gene is TRBV27.

Additional gene information for TRBV28 Gene

No data available for Entrez Gene Summary , CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for TRBV28 Gene

Genomics for TRBV28 Gene

GeneHancer (GH) Regulatory Elements for TRBV28 Gene

Promoters and enhancers for TRBV28 Gene
GeneHancer (GH) Identifier GH Type GH
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH07J142710 Enhancer 1.1 Ensembl ENCODE dbSUPER 43 -4.5 -4480 10.8 CTCF JUN TEAD4 RAD21 YY1 FOSL1 TCF12 DIDO1 ZNF316 NCOR1 TRBV27 TRBV28 EPHB6 LOC100507507 TRBVB TRB
GH07J142722 Enhancer 0.8 Ensembl ENCODE dbSUPER 33.6 +2.0 2033 1.4 PKNOX1 CREB1 PGBD4P1 TRBV28 TRBV7-3 TRBV29-1 TRB
GH07J142709 Enhancer 0.4 ENCODE 42.3 -10.6 -10627 0.9 GABPB1 NRF1 TRBVB TRBV28 TRBV26 TRB
GH07J142645 Enhancer 0.6 Ensembl ENCODE 25.2 -74.2 -74224 1.3 CREB1 RCOR1 TRBV23-1 TRBV28 SSBP1 TRBV24-1 TRB
GH07J142670 Enhancer 0.4 ENCODE 35.2 -49.3 -49319 1.5 NR2F1 SPI1 TRBV25-1 TRBV28 EPHB6 TRBVA TRB
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data dump

GeneHancers around TRBV28 on UCSC Golden Path with GeneCards custom track

Genomic Locations for TRBV28 Gene

Genomic Locations for TRBV28 Gene
501 bases
Plus strand

Genomic View for TRBV28 Gene

Genes around TRBV28 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
TRBV28 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for TRBV28 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for TRBV28 Gene

Proteins for TRBV28 Gene

  • Protein details for TRBV28 Gene (UniProtKB/TrEMBL)

    Protein Symbol:
    Recommended name:
    T cell receptor beta variable 28
    Protein Accession:
    Secondary Accessions:
    • A0A0G2JN94

    Protein attributes for TRBV28 Gene

    114 amino acids
    Molecular mass:
    13166 Da
    Quaternary structure:
    No Data Available

    Three dimensional structures from OCA and Proteopedia for TRBV28 Gene

neXtProt entry for TRBV28 Gene

Post-translational modifications for TRBV28 Gene

No Post-translational modifications

Other Protein References for TRBV28 Gene

ENSEMBL proteins:

No data available for DME Specific Peptides for TRBV28 Gene

Domains & Families for TRBV28 Gene

Gene Families for TRBV28 Gene

Protein Domains for TRBV28 Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with TRBV28: view

No data available for Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for TRBV28 Gene

Function for TRBV28 Gene

Phenotypes From GWAS Catalog for TRBV28 Gene

Animal Model Products

Clone Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for TRBV28 Gene

Localization for TRBV28 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for TRBV28 Gene

Pathways & Interactions for TRBV28 Gene

SuperPathways for TRBV28 Gene

No Data Available

Interacting Proteins for TRBV28 Gene

Gene Ontology (GO) - Biological Process for TRBV28 Gene


No data available for Pathways by source and SIGNOR curated interactions for TRBV28 Gene

Drugs & Compounds for TRBV28 Gene

No Compound Related Data Available

Transcripts for TRBV28 Gene

mRNA/cDNA for TRBV28 Gene

Clone Products

Alternative Splicing Database (ASD) splice patterns (SP) for TRBV28 Gene

No ASD Table

Relevant External Links for TRBV28 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for TRBV28 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for TRBV28 Gene

mRNA differential expression in normal tissues according to GTEx for TRBV28 Gene

This gene is overexpressed in Whole Blood (x34.2) and Spleen (x4.6).

Protein differential expression in normal tissues from HIPED for TRBV28 Gene

This gene is overexpressed in Tlymphocyte (51.6), CD4 Tcells (8.8), and Peripheral blood mononuclear cells (7.0).

Integrated Proteomics: protein expression in normal tissues and cell lines from MOPED for TRBV28 Gene

Protein tissue co-expression partners for TRBV28 Gene

- Elite partner

NURSA nuclear receptor signaling pathways regulating expression of TRBV28 Gene:

genes like me logo Genes that share expression patterns with TRBV28: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for TRBV28 Gene

Orthologs for TRBV28 Gene

This gene was present in the common ancestor of chordates.

Orthologs for TRBV28 Gene

Organism Taxonomy Gene Similarity Type Details
(Gallus gallus)
Aves -- 34
  • 35 (a)
-- 34
  • 30 (a)
-- 34
  • 28 (a)
(Anolis carolinensis)
Reptilia -- 34
  • 29 (a)
-- 34
  • 21 (a)
Species where no ortholog for TRBV28 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chimpanzee (Pan troglodytes)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • cow (Bos Taurus)
  • dog (Canis familiaris)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • mouse (Mus musculus)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for TRBV28 Gene

Gene Tree for TRBV28 (if available)
Gene Tree for TRBV28 (if available)
Evolutionary constrained regions (ECRs) for TRBV28: view image

Paralogs for TRBV28 Gene

genes like me logo Genes that share paralogs with TRBV28: view

Variants for TRBV28 Gene

Additional Variant Information for TRBV28 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Sequence variations from dbSNP and Humsavar , Structural Variations from Database of Genomic Variants (DGV) and Variation tolerance for TRBV28 Gene

Disorders for TRBV28 Gene

No disorders were found for TRBV28 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot , Genatlas and External Links for TRBV28 Gene

Publications for TRBV28 Gene

  1. The complete 685-kilobase DNA sequence of the human beta T cell receptor locus. (PMID: 8650574) Rowen L … Hood L (Science (New York, N.Y.) 1996) 2 3 58
  2. Level of human TCRBV3S1 (V beta 3) expression correlates with allelic polymorphism in the spacer region of the recombination signal sequence. (PMID: 8163948) Posnett DN … Concannon P (The Journal of experimental medicine 1994) 3 58
  3. The genomic structure of human V beta 6 T cell antigen receptor genes. (PMID: 1660526) Li Y … Posnett DN (The Journal of experimental medicine 1991) 3 58

Products for TRBV28 Gene

Sources for TRBV28 Gene

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