Free for academic non-profit institutions. Other users need a Commercial license
TRBV11-2 (T Cell Receptor Beta Variable 11-2) is a Protein Coding gene. Among its related pathways are Immune response Function of MEF2 in T lymphocytes and Th17 cell differentiation.
GeneHancer (GH) Identifier | GH Type | GH Score |
GH Sources | Gene Association Score | Total Score | TSS distance (kb) | Number of Genes Away | Size (kb) | Transcription Factor Binding Sites |
Gene Targets |
---|---|---|---|---|---|---|---|---|---|---|
GH07J142432 | Enhancer | 0.2 | Ensembl | 250.7 | -1.9 | -1894 | 0.8 | TRBV11-2 TRBV10-2 TRBV6-5 lnc-PRSS2-6 TRB | ||
GH07J142434 | Enhancer | 0.2 | Ensembl | 250.7 | +0.6 | 606 | 1.8 | TRBV11-2 TRBV10-2 TRBV12-2 TRBV6-5 lnc-PRSS2-6 TRB | ||
GH07J142964 | Enhancer | 0.8 | Ensembl | 4.7 | +530.5 | 530506 | 0.8 | MNT IKZF1 BHLHE40 ZNF395 MAFF ZEB2 TAF9B NCOR1 MYNN ZNF316 | TCAF1 TRBV11-2 KEL HSALNG0061937 OR9A2 | |
GH07J143012 | Enhancer | 0.8 | Ensembl ENCODE | 4.9 | +581.8 | 581806 | 8.6 | ZFP91 ZNF316 NFE2 MAFK SRF JUND MAFG MAFF POLR2A SPI1 | ZYX OR9P1P OR6V1 TAS2R39 KEL LLCFC1 TRPV5 TRBV11-2 HSALNG0061937 OR9A2 | |
GH07J142974 | Enhancer | 0.2 | Ensembl | 5.8 | +540.9 | 540906 | 0.4 | TRBV11-2 TCAF2 KEL HSALNG0061937 OR9A2 |
GO ID | Qualified GO term | Evidence | PubMed IDs |
---|---|---|---|
GO:0005886 | plasma membrane | IBA | 21873635 |
GO:0042101 | T cell receptor complex | IEA | -- |
SuperPathway | Contained pathways | ||
---|---|---|---|
1 | Immune response NFAT in immune response |
Immune response ICOS pathway in T-helper cell
.56
Immune response NFAT in immune response
.56
|
Immune response T cell receptor signaling pathway
.52
Immune response CD28 signaling
.52
|
2 | G-protein signaling N-RAS regulation pathway |
G-protein signaling N-RAS regulation pathway
.52
|
Immune response Antigen presentation by MHC class II
.52
|
3 | G-protein signaling_Rap1A regulation pathway |
G-protein signaling_Rap1A regulation pathway
-
|
|
4 | G-protein signaling_Regulation of RAC1 activity |
G-protein signaling_Regulation of RAC1 activity
-
|
|
5 | Antigen processing-Cross presentation |
Immune response Antigen presentation by MHC class I
.51
|
GO ID | Qualified GO term | Evidence | PubMed IDs |
---|---|---|---|
GO:0002250 | adaptive immune response | IEA | -- |
GO:0007166 | cell surface receptor signaling pathway | IBA | 21873635 |
No disorders were found for TRBV11-2 Gene.