Aliases for TRAPPC9 Gene
External Ids for TRAPPC9 Gene
Previous GeneCards Identifiers for TRAPPC9 Gene
This gene encodes a protein that likely plays a role in NF-kappa-B signaling. Mutations in this gene have been associated with autosomal-recessive cognitive disability. Alternatively spliced transcript variants have been described.[provided by RefSeq, Feb 2010]
GeneCards Summary for TRAPPC9 Gene
TRAPPC9 (Trafficking Protein Particle Complex 9) is a Protein Coding gene. Diseases associated with TRAPPC9 include Intellectual Disability-Obesity-Brain Malformations-Facial Dysmorphism Syndrome and Autosomal Recessive Non-Syndromic Intellectual Disability. Among its related pathways are Metabolism of proteins and RAB GEFs exchange GTP for GDP on RABs.
UniProtKB/Swiss-Prot Summary for TRAPPC9 Gene
Functions as an activator of NF-kappa-B through increased phosphorylation of the IKK complex. May function in neuronal cells differentiation. May play a role in vesicular transport from endoplasmic reticulum to Golgi.