Aliases for TRAPPC6B Gene
External Ids for TRAPPC6B Gene
Previous GeneCards Identifiers for TRAPPC6B Gene
TRAPPC6B is a component of TRAPP complexes, which are tethering complexes involved in vesicle transport (Kummel et al., 2005 [PubMed 16025134]).[supplied by OMIM, Mar 2008]
GeneCards Summary for TRAPPC6B Gene
TRAPPC6B (Trafficking Protein Particle Complex Subunit 6B) is a Protein Coding gene. Diseases associated with TRAPPC6B include Neurodevelopmental Disorder With Microcephaly, Epilepsy, And Brain Atrophy and Epilepsy. Among its related pathways are Vesicle-mediated transport and RAB GEFs exchange GTP for GDP on RABs. An important paralog of this gene is TRAPPC6A.
UniProtKB/Swiss-Prot Summary for TRAPPC6B Gene
Component of a transport protein particle (TRAPP) complex that may function in specific stages of inter-organelle traffic (PubMed:16025134, PubMed:16828797). Specifically involved in the early development of neural circuitry, likely by controlling the frequency and amplitude of intracellular calcium transients implicated in the regulation of neuron differentiation and survival (Probable).