Aliases for TRAPPC6A Gene
External Ids for TRAPPC6A Gene
Previous GeneCards Identifiers for TRAPPC6A Gene
This gene encodes a component of the trafficking protein particle complex, which tethers transport vesicles to the cis-Golgi membrane. Loss of expression of the related gene in mouse affects coat and eye pigmentation, suggesting that the encoded protein may be involved in melanosome biogenesis. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Aug 2012]
GeneCards Summary for TRAPPC6A Gene
TRAPPC6A (Trafficking Protein Particle Complex Subunit 6A) is a Protein Coding gene. Diseases associated with TRAPPC6A include Spondyloepiphyseal Dysplasia Tarda, X-Linked and Spinal Muscular Atrophy, Type Iv. Among its related pathways are Vesicle-mediated transport and RAB GEFs exchange GTP for GDP on RABs. An important paralog of this gene is TRAPPC6B.
UniProtKB/Swiss-Prot Summary for TRAPPC6A Gene
May play a role in vesicular transport during the biogenesis of melanosomes.