Aliases for TRAPPC4 Gene
External Ids for TRAPPC4 Gene
Previous GeneCards Identifiers for TRAPPC4 Gene
GeneCards Summary for TRAPPC4 Gene
TRAPPC4 (Trafficking Protein Particle Complex Subunit 4) is a Protein Coding gene. Diseases associated with TRAPPC4 include Neurodevelopmental Disorder With Epilepsy, Spasticity, And Brain Atrophy and Neurodevelopmental Disorder With Progressive Microcephaly, Spasticity, And Brain Anomalies. Among its related pathways are MET promotes cell motility and Degradation of the extracellular matrix. Gene Ontology (GO) annotations related to this gene include Rab guanyl-nucleotide exchange factor activity. An important paralog of this gene is TRAPPC1.
UniProtKB/Swiss-Prot Summary for TRAPPC4 Gene
Core component of the TRAPP complexes which has a function of guanine nucleotide exchange factor activity for Rab1 GTPase (Probable). Plays a role in vesicular transport from endoplasmic reticulum to Golgi and autophagy (PubMed:31794024). May play a role in dendrite postsynaptic membrane trafficking (By similarity).