Aliases for TRAM1 Gene
External Ids for TRAM1 Gene
Previous GeneCards Identifiers for TRAM1 Gene
This gene encodes a multi-pass membrane protein that is part of the mammalian endoplasmic reticulum. The encoded protein influences glycosylation and facilitates the translocation of secretory proteins across the endoplasmic reticulum membrane by regulating which domains of the nascent polypeptide chain are visible to the cytosol during a translocational pause. [provided by RefSeq, Oct 2009]
GeneCards Summary for TRAM1 Gene
TRAM1 (Translocation Associated Membrane Protein 1) is a Protein Coding gene. Diseases associated with TRAM1 include Ceroid Lipofuscinosis, Neuronal, 8, Northern Epilepsy Variant and Orofaciodigital Syndrome Vi. Among its related pathways are Viral mRNA Translation and Diseases associated with the TLR signaling cascade. An important paralog of this gene is TRAM1L1.
UniProtKB/Swiss-Prot Summary for TRAM1 Gene
Stimulatory or required for the translocation of secretory proteins across the ER membrane.