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Aliases for TRAJ6 Gene

Aliases for TRAJ6 Gene

  • T Cell Receptor Alpha Joining 6 2 3
  • T-Cell Receptor Alpha Joining 6 5

External Ids for TRAJ6 Gene

Previous GeneCards Identifiers for TRAJ6 Gene

  • GC14U990385
  • GC14P020998
  • GC14P022079
  • GC14P023063
  • GC14P023127
  • GC14P023189
  • GC14P023240
  • GC14P023302
  • GC14P023380
  • GC14P023452
  • GC14P023535
  • GC14P023626
  • GC14P023770
  • GC14P022559
  • GC14P022662
  • GC14P022747
  • GC14P022812
  • GC14P023809
  • GC14P023903
  • GC14P024011

Summaries for TRAJ6 Gene

Entrez Gene Summary for TRAJ6 Gene

  • T cell receptors recognize foreign antigens which have been processed as small peptides and bound to major histocompatibility complex (MHC) molecules at the surface of antigen presenting cells (APC). Each T cell receptor is a dimer consisting of one alpha and one beta chain or one delta and one gamma chain. In a single cell, the T cell receptor loci are rearranged and expressed in the order delta, gamma, beta, and alpha. If both delta and gamma rearrangements produce functional chains, the cell expresses delta and gamma. If not, the cell proceeds to rearrange the beta and alpha loci. This region represents the germline organization of the T cell receptor alpha and delta loci. Both the alpha and delta loci include V (variable), J (joining), and C (constant) segments and the delta locus also includes diversity (D) segments. The delta locus is situated within the alpha locus, between the alpha V and J segments. During T cell development, the delta chain is synthesized by a recombination event at the DNA level joining a D segment with a J segment; a V segment is then joined to the D-J gene. The alpha chain is synthesized by recombination joining a single V segment with a J segment. For both chains, the C segment is later joined by splicing at the RNA level. Recombination of many different V segments with several J segments provides a wide range of antigen recognition. Additional diversity is attained by junctional diversity, resulting from the random additional of nucleotides by terminal deoxynucleotidyltransferase. Five variable segments can be used in either alpha or delta chains and are described by TRAV/DV symbols. Several V and J segments of the alpha locus are known to be incapable of encoding a protein and are considered pseudogenes. [provided by RefSeq, Aug 2016]

GeneCards Summary for TRAJ6 Gene

TRAJ6 (T Cell Receptor Alpha Joining 6) is a Protein Coding gene.

Additional gene information for TRAJ6 Gene

No data available for CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for TRAJ6 Gene

Genomics for TRAJ6 Gene

GeneHancer (GH) Regulatory Elements for TRAJ6 Gene

Promoters and enhancers for TRAJ6 Gene
GeneHancer (GH) Identifier GH Type GH
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH14I022504 Promoter/Enhancer 2.3 FANTOM5 Ensembl ENCODE dbSUPER 550.8 -0.9 -885 66.7 MLX ZFP64 DMAP1 IRF4 YY1 SLC30A9 ZNF213 ZNF143 SP3 SSRP1 GC14P024183 GC14P024201 TRAJ6 TRAJ7 ABHD4 DAD1 C14orf93 MMP14 LOC105370399 TRAC
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data dump

GeneHancers around TRAJ6 on UCSC Golden Path with GeneCards custom track

Genomic Locations for TRAJ6 Gene

Genomic Locations for TRAJ6 Gene
62 bases
Plus strand

Genomic View for TRAJ6 Gene

Genes around TRAJ6 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
TRAJ6 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for TRAJ6 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for TRAJ6 Gene

Proteins for TRAJ6 Gene

  • Protein details for TRAJ6 Gene (UniProtKB/TrEMBL)

    Protein Symbol:
    Recommended name:
    T-cell receptor alpha joining 6
    Protein Accession:

    Protein attributes for TRAJ6 Gene

    21 amino acids
    Molecular mass:
    2129 Da
    Quaternary structure:
    No Data Available

neXtProt entry for TRAJ6 Gene

Post-translational modifications for TRAJ6 Gene

No Post-translational modifications

Other Protein References for TRAJ6 Gene

ENSEMBL proteins:

No data available for DME Specific Peptides for TRAJ6 Gene

Domains & Families for TRAJ6 Gene

Gene Families for TRAJ6 Gene

Protein Domains for TRAJ6 Gene


Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with TRAJ6: view

No data available for Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for TRAJ6 Gene

Function for TRAJ6 Gene

Phenotypes From GWAS Catalog for TRAJ6 Gene

Animal Model Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for TRAJ6 Gene

Localization for TRAJ6 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for TRAJ6 Gene

Pathways & Interactions for TRAJ6 Gene

SuperPathways for TRAJ6 Gene

No Data Available

Interacting Proteins for TRAJ6 Gene

Gene Ontology (GO) - Biological Process for TRAJ6 Gene


No data available for Pathways by source and SIGNOR curated interactions for TRAJ6 Gene

Drugs & Compounds for TRAJ6 Gene

No Compound Related Data Available

Transcripts for TRAJ6 Gene

mRNA/cDNA for TRAJ6 Gene

Clone Products

Alternative Splicing Database (ASD) splice patterns (SP) for TRAJ6 Gene

No ASD Table

Relevant External Links for TRAJ6 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for TRAJ6 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for TRAJ6 Gene

NURSA nuclear receptor signaling pathways regulating expression of TRAJ6 Gene:

genes like me logo Genes that share expression patterns with TRAJ6: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for TRAJ6 Gene

Orthologs for TRAJ6 Gene

Evolution for TRAJ6 Gene

Gene Tree for TRAJ6 (if available)
Gene Tree for TRAJ6 (if available)

No data available for Orthologs for TRAJ6 Gene

Paralogs for TRAJ6 Gene

No data available for Paralogs for TRAJ6 Gene

Variants for TRAJ6 Gene

Additional Variant Information for TRAJ6 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Sequence variations from dbSNP and Humsavar , Structural Variations from Database of Genomic Variants (DGV) and Variation tolerance for TRAJ6 Gene

Disorders for TRAJ6 Gene

No disorders were found for TRAJ6 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot , Genatlas and External Links for TRAJ6 Gene

Publications for TRAJ6 Gene

  1. The human T-cell receptor TCRAC/TCRDC (C alpha/C delta) region: organization, sequence, and evolution of 97.6 kb of DNA. (PMID: 8188290) Koop BF … Hood L (Genomics 1994) 2 3 58
  2. The mechanism of chromosome 14 inversion in a human T cell lymphoma. (PMID: 3036367) Baer R … Rabbitts TH (Cell 1987) 2 3 58

Products for TRAJ6 Gene

Sources for TRAJ6 Gene

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