Aliases for TRAF3IP3 Gene
External Ids for TRAF3IP3 Gene
Previous GeneCards Identifiers for TRAF3IP3 Gene
The gene encodes a protein that mediates cell growth by modulating the c-Jun N-terminal kinase signal transduction pathway. The encoded protein may also interact with a large multi-protein assembly containing the phosphatase 2A catalytic subunit. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2013]
GeneCards Summary for TRAF3IP3 Gene
TRAF3IP3 (TRAF3 Interacting Protein 3) is a Protein Coding gene. Diseases associated with TRAF3IP3 include Pityriasis Rubra Pilaris. Gene Ontology (GO) annotations related to this gene include DNA-binding transcription factor activity and sequence-specific DNA binding. An important paralog of this gene is SLMAP.
UniProtKB/Swiss-Prot Summary for TRAF3IP3 Gene
May function as an adapter molecule that regulates TRAF3-mediated JNK activation.