Aliases for TPTE2P1 Gene

Aliases for TPTE2P1 Gene

  • Transmembrane Phosphoinositide 3-Phosphatase And Tensin Homolog 2 Pseudogene 1 2 3 5
  • Putative Phosphatidylinositol 3,4,5-Trisphosphate 3-Phosphatase TPTE2P1 4
  • TPTE2P1 5

External Ids for TPTE2P1 Gene

Previous GeneCards Identifiers for TPTE2P1 Gene

  • GC00U922913
  • GC13M025499
  • GC13M006316

Summaries for TPTE2P1 Gene

GeneCards Summary for TPTE2P1 Gene

TPTE2P1 (Transmembrane Phosphoinositide 3-Phosphatase And Tensin Homolog 2 Pseudogene 1) is a Pseudogene.

Additional gene information for TPTE2P1 Gene

No data available for Entrez Gene Summary , CIViC Summary , UniProtKB/Swiss-Prot Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , Rfam classification and piRNA Summary for TPTE2P1 Gene

Genomics for TPTE2P1 Gene

GeneHancer (GH) Regulatory Elements Pubs

Promoters and enhancers for TPTE2P1 Gene
GeneHancer (GH) Identifier GH Type GH
Score
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH13J024968 Promoter 1.1 Ensembl CraniofacialAtlas 613.6 +0.4 386 1 CTCF ZNF143 REST KLF9 RAD21 ZNF444 ZBTB17 FOXP1 FOXA1 ZNF654 TPTE2P1 lnc-CENPJ-1 piR-30838-001 piR-31432-137 piR-49732-130 piR-46662-135 piR-53431-138 piR-56759-131 piR-54764-132 CENPJ
GH13J024922 Promoter/Enhancer 2 EPDnew Ensembl ENCODE CraniofacialAtlas 9.1 +45.7 45675 3.2 SP1 CREB1 PRDM10 ZNF629 REST RFX1 SIX5 LEF1 IKZF1 ZNF692 CENPJ lnc-RNF17-5 TPTE2P1 SLC25A15P3 RNF17 lnc-AMER2-3
GH13J025768 Enhancer 0.9 Ensembl ENCODE 13.1 -802.0 -801959 4.5 FOXA1 ZIC2 ATF7 RFX1 ESRRA ZNF623 ZBTB11 GATA3 ELF1 JUND piR-57944 TPTE2P1 WASF3 SHISA2 piR-38423-014 ATP8A2
GH13J025151 Enhancer 0.7 Ensembl ENCODE dbSUPER 13.4 -184.6 -184614 3.4 ZNF157 YY1 GATA3 lnc-PABPC3-4 TPTE2P1 LINC00463 lnc-MTMR6-3 AMER2 PABPC3
GH13J024957 Enhancer 0.7 Ensembl ENCODE 13.9 +11.3 11286 1.2 CTBP1 FEZF1 PRDM10 ZEB2 IKZF1 CBFA2T3 SMARCA4 TPTE2P1 CENPJ piR-38580-073 lnc-CENPJ-3 lnc-RNF17-4 lnc-CENPJ-1 PABPC3
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data from 2017 publication | Request up-to-date GeneHancer data (full dataset)

GeneHancers around TPTE2P1 on the GeneHancer Hub at the UCSC Golden Path

Genomic Locations for TPTE2P1 Gene

Genomic Locations for TPTE2P1 Gene
chr13:24,924,677-24,968,487
(GRCh38/hg38)
Size:
43,811 bases
Orientation:
Minus strand
chr13:25,498,815-25,542,625
(GRCh37/hg19)
Size:
43,811 bases
Orientation:
Minus strand

Genomic View for TPTE2P1 Gene

Genes around TPTE2P1 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
TPTE2P1 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for TPTE2P1 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for TPTE2P1 Gene

Proteins for TPTE2P1 Gene

  • Protein details for TPTE2P1 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q5T6R2-TPT2L_HUMAN
    Recommended name:
    Putative phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase TPTE2P1
    Protein Accession:
    Q5T6R2
    Secondary Accessions:
    • B3KST4
    • B4DMH9

    Protein attributes for TPTE2P1 Gene

    Size:
    138 amino acids
    Molecular mass:
    15541 Da
    Quaternary structure:
    No Data Available

    Alternative splice isoforms for TPTE2P1 Gene

    UniProtKB/Swiss-Prot:

neXtProt entry for TPTE2P1 Gene

Post-translational modifications for TPTE2P1 Gene

No Post-translational modifications

No data available for DME Specific Peptides for TPTE2P1 Gene

Domains & Families for TPTE2P1 Gene

Protein Domains for TPTE2P1 Gene

InterPro:
ProtoNet:

Suggested Antigen Peptide Sequences for TPTE2P1 Gene

GenScript: Design optimal peptide antigens:
  • Putative phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase TPTE2P1 (TPT2L_HUMAN)
genes like me logo Genes that share domains with TPTE2P1: view

No data available for Gene Families , Graphical View of Domain Structure and UniProtKB/Swiss-Prot for TPTE2P1 Gene

Function for TPTE2P1 Gene

Phenotypes From GWAS Catalog for TPTE2P1 Gene

Phenotypes for TPTE2P1 Gene

genes like me logo Genes that share phenotypes with TPTE2P1: view

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for TPTE2P1 Gene

Localization for TPTE2P1 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for TPTE2P1 Gene

Pathways & Interactions for TPTE2P1 Gene

PathCards logo

SuperPathways for TPTE2P1 Gene

No Data Available

Gene Ontology (GO) - Biological Process for TPTE2P1 Gene

None

No data available for Pathways by source , Interacting Proteins and SIGNOR curated interactions for TPTE2P1 Gene

Drugs & Compounds for TPTE2P1 Gene

No Compound Related Data Available

Transcripts for TPTE2P1 Gene

mRNA/cDNA for TPTE2P1 Gene

1 REFSEQ mRNAs :
3 NCBI additional mRNA sequence :
5 Ensembl transcripts including schematic representations, and UCSC links to gene/alias where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for TPTE2P1 Gene

No ASD Table

Relevant External Links for TPTE2P1 Gene

GeneLoc Exon Structure for
TPTE2P1

Expression for TPTE2P1 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and SAGE for TPTE2P1 Gene

mRNA differential expression in normal tissues according to GTEx for TPTE2P1 Gene

This gene is overexpressed in Thyroid (x5.7), Brain - Cerebellar Hemisphere (x5.5), and Brain - Cerebellum (x5.0).

Protein differential expression in normal tissues from HIPED for TPTE2P1 Gene

This gene is overexpressed in Heart (47.6) and Pancreatic juice (21.4).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB and MOPED for TPTE2P1 Gene



Protein tissue co-expression partners for TPTE2P1 Gene

- Elite partner

Transcriptomic regulation report from SPP (The Signaling Pathways Project) for TPTE2P1

SOURCE GeneReport for Unigene cluster for TPTE2P1 Gene:

Hs.620592
genes like me logo Genes that share expression patterns with TPTE2P1: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for TPTE2P1 Gene

Orthologs for TPTE2P1 Gene

Evolution for TPTE2P1 Gene

ENSEMBL:
Gene Tree for TPTE2P1 (if available)
TreeFam:
Gene Tree for TPTE2P1 (if available)

No data available for Orthologs for TPTE2P1 Gene

Paralogs for TPTE2P1 Gene

(4) SIMAP similar genes for TPTE2P1 Gene using alignment to 1 proteins:

  • TPT2L_HUMAN
genes like me logo Genes that share paralogs with TPTE2P1: view

No data available for Paralogs for TPTE2P1 Gene

Variants for TPTE2P1 Gene

Structural Variations from Database of Genomic Variants (DGV) for TPTE2P1 Gene

Variant ID Type Subtype PubMed ID
dgv537e212 CNV loss 25503493
esv28932 CNV loss 19812545
esv3362432 CNV insertion 20981092
nsv1041986 CNV gain 25217958
nsv1116459 OTHER inversion 24896259
nsv1153497 OTHER inversion 26484159
nsv1160094 CNV deletion 26073780
nsv442664 CNV loss 18776908
nsv964 CNV deletion 18451855
nsv977219 CNV duplication 23825009

Additional Variant Information for TPTE2P1 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
TPTE2P1

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Sequence variations, with clinical significance, from ClinVar and Humsavar, with links to dbSNP , Additional dbSNP identifiers (rs#s) and Variation tolerance for TPTE2P1 Gene

Disorders for TPTE2P1 Gene

Additional Disease Information for TPTE2P1

No disorders were found for TPTE2P1 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for TPTE2P1 Gene

Publications for TPTE2P1 Gene

  1. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T … Sugano S (Nature genetics 2004) 3 4
  2. Novel genetic loci identified for the pathophysiology of childhood obesity in the Hispanic population. (PMID: 23251661) Comuzzie AG … Butte NF (PloS one 2012) 3
  3. The DNA sequence and analysis of human chromosome 13. (PMID: 15057823) Dunham A … Ross MT (Nature 2004) 4

Products for TPTE2P1 Gene

Sources for TPTE2P1 Gene