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TPTE2P1 Gene(Pseudogene)

Transmembrane Phosphoinositide 3-Phosphatase And Tensin Homolog 2 Pseudogene 1

GCID:
GC13M024924
GIFtS:
23
Genes Participants
UDN Logo

Aliases for TPTE2P1 Gene

Aliases for TPTE2P1 Gene

  • Transmembrane Phosphoinositide 3-Phosphatase And Tensin Homolog 2 Pseudogene 1 2 3 5

External Ids for TPTE2P1 Gene

Previous GeneCards Identifiers for TPTE2P1 Gene

  • GC00U922913
  • GC13M025499
  • GC13M006316

Summaries for TPTE2P1 Gene

GeneCards Summary for TPTE2P1 Gene

TPTE2P1 (Transmembrane Phosphoinositide 3-Phosphatase And Tensin Homolog 2 Pseudogene 1) is a Pseudogene.

Additional gene information for TPTE2P1 Gene

No data available for Entrez Gene Summary , CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for TPTE2P1 Gene

Genomics for TPTE2P1 Gene

Products:

  1. Regulatory Element

GeneHancer (GH) Regulatory Elements for TPTE2P1 Gene

Promoters and enhancers for TPTE2P1 Gene
GeneHancer (GH) Identifier GH Type GH
Score		 GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites		 Gene Targets
GH13I024968 Promoter 0.9 Ensembl 561 +0.2 186 0.6 CTCF ZNF654 REST RAD21 FOXA1 ZSCAN21 KLF9 ZNF143 ZNF444 ZBTB17 TPTE2P1 CENPJ SLC25A15P3
GH13I024921 Promoter/Enhancer 2.1 EPDnew Ensembl ENCODE 9.1 +45.4 45351 2.6 HDGF PKNOX1 ARNT ARID4B SIN3A FEZF1 DMAP1 IRF4 YY1 POLR2B CENPJ TPTE2P1 RNF17 ENSG00000273628
GH13I025371 Promoter/Enhancer 1.2 EPDnew Ensembl 5 -403.8 -403817 1.6 ZSCAN5A CTCF MXI1 KLF1 ZNF777 ZSCAN4 CDC5L ZNF2 ZNF335 ZFHX2 ATP8A2 TPTE2P1 GC13M025452
GH13I024922 Enhancer 0.5 Ensembl 9.9 +47.4 47386 0.2 ATF4 IKZF1 CEBPG EP300 CENPJ TPTE2P1 GC13P024795 PIR31198
GH13I024925 Enhancer 0.7 ENCODE 6.6 +42.7 42678 0.7 ELF3 SOX13 TFAP4 FOXA2 SAP130 MLX RARA NR2F6 THAP11 MIXL1 RNF17 TPTE2P1 CENPJ ENSG00000273628
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data dump

GeneHancers around TPTE2P1 on UCSC Golden Path with GeneCards custom track

Genomic Locations for TPTE2P1 Gene

Genomic Locations for TPTE2P1 Gene
chr13:24,924,677-24,968,487
(GRCh38/hg38)
Size:
43,811 bases
Orientation:
Minus strand
chr13:25,498,815-25,542,625
(GRCh37/hg19)

Genomic View for TPTE2P1 Gene

Genes around TPTE2P1 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
TPTE2P1 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for TPTE2P1 Gene
GeneLoc Logo Genomic Neighborhood • Exon Structure • Gene Density

RefSeq DNA sequence for TPTE2P1 Gene

Proteins for TPTE2P1 Gene

Products:

  1. Antibody
  2. Protein
  3. Assay

  • Protein details for TPTE2P1 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q5T6R2-TPT2L_HUMAN
    Recommended name:
    Putative phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase TPTE2P1
    Protein Accession:
    Q5T6R2
    Secondary Accessions:
    • B3KST4
    • B4DMH9

    Protein attributes for TPTE2P1 Gene

    Size:
    138 amino acids
    Molecular mass:
    15541 Da
    Quaternary structure:
    No Data Available

    Alternative splice isoforms for TPTE2P1 Gene

    UniProtKB/Swiss-Prot:

neXtProt entry for TPTE2P1 Gene

Protein Expression for TPTE2P1 Gene

See protein expression from ProteomicsDB, MOPED, PaxDb, and MaxQB

Post-translational modifications for TPTE2P1 Gene

No Post-translational modifications

No data available for DME Specific Peptides for TPTE2P1 Gene

Domains & Families for TPTE2P1 Gene

Protein Domains for TPTE2P1 Gene

InterPro:
ProtoNet:

Suggested Antigen Peptide Sequences for TPTE2P1 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with TPTE2P1: view

No data available for Gene Families and UniProtKB/Swiss-Prot for TPTE2P1 Gene

Function for TPTE2P1 Gene

Products:

  1. Animal Model
  2. CRISPR
  3. miRNA
  4. Inhibitory RNA
  5. Clone
  6. Cell Line

Phenotypes From GWAS Catalog for TPTE2P1 Gene

Phenotypes for TPTE2P1 Gene

GenomeRNAi human phenotypes for TPTE2P1:
genes like me logo Genes that share phenotypes with TPTE2P1: view

Animal Model Products

Inhibitory RNA Products

Clone Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for TPTE2P1 Gene

Localization for TPTE2P1 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for TPTE2P1 Gene

Pathways & Interactions for TPTE2P1 Gene

SuperPathways for TPTE2P1 Gene

PathCards logo More details on SuperPathways for TPTE2P1
No Data Available

Interacting Proteins for TPTE2P1 Gene

Gene Ontology (GO) - Biological Process for TPTE2P1 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for TPTE2P1 Gene

Drugs & Compounds for TPTE2P1 Gene

Products:

  1. Drug
No Compound Related Data Available

Transcripts for TPTE2P1 Gene

Products:

  1. CRISPR
  2. miRNA
  3. Inhibitory RNA
  4. Clone

mRNA/cDNA for TPTE2P1 Gene

(1) REFSEQ mRNAs :
(5) Additional mRNA sequences :
(4) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for TPTE2P1 Gene

Transmembrane phosphoinositide 3-phosphatase and tensin homolog 2 pseudogene 1:
Representative Sequences:

Inhibitory RNA Products

Clone Products

Alternative Splicing Database (ASD) splice patterns (SP) for TPTE2P1 Gene

No ASD Table

Relevant External Links for TPTE2P1 Gene

GeneLoc Exon Structure for
TPTE2P1
ECgene alternative splicing isoforms for
TPTE2P1

Expression for TPTE2P1 Gene

Products:

  1. Primer
  2. Gene Expression Assay

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for TPTE2P1 Gene

mRNA expression in normal human tissues for TPTE2P1 Gene
mRNA expression by GTEx for TPTE2P1 Gene

mRNA differential expression in normal tissues according to GTEx for TPTE2P1 Gene

This gene is overexpressed in Thyroid (x5.7), Brain - Cerebellar Hemisphere (x5.5), and Brain - Cerebellum (x5.0).

Protein differential expression in normal tissues from HIPED for TPTE2P1 Gene

This gene is overexpressed in Heart (47.6) and Pancreatic juice (21.4).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB and MOPED for TPTE2P1 Gene



Protein tissue co-expression partners for TPTE2P1 Gene

- Elite partner

NURSA nuclear receptor signaling pathways regulating expression of TPTE2P1 Gene:

TPTE2P1

SOURCE GeneReport for Unigene cluster for TPTE2P1 Gene:

Hs.620592
genes like me logo Genes that share expression patterns with TPTE2P1: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for TPTE2P1 Gene

Orthologs for TPTE2P1 Gene

Evolution for TPTE2P1 Gene

ENSEMBL:
Gene Tree for TPTE2P1 (if available)
TreeFam:
Gene Tree for TPTE2P1 (if available)

No data available for Orthologs for TPTE2P1 Gene

Paralogs for TPTE2P1 Gene

(4) SIMAP similar genes for TPTE2P1 Gene using alignment to 1 proteins:

genes like me logo Genes that share paralogs with TPTE2P1: view

No data available for Paralogs for TPTE2P1 Gene

Variants for TPTE2P1 Gene

Products:

  1. SNP Genotyping and Copy Number Assay

Sequence variations from dbSNP and Humsavar for TPTE2P1 Gene

SNP ID Clin Chr 13 pos Variation AA Info Type
rs1000098322 -- 24,970,144(-) A/G upstream_transcript_variant
rs1000212064 -- 24,963,737(-) C/T intron_variant
rs1000238682 -- 24,941,088(-) G/T intron_variant
rs1000420894 -- 24,957,772(-) C/T intron_variant
rs1000667054 -- 24,963,990(-) A/T intron_variant

Structural Variations from Database of Genomic Variants (DGV) for TPTE2P1 Gene

Variant ID Type Subtype PubMed ID
dgv537e212 CNV loss 25503493
esv28932 CNV loss 19812545
esv3362432 CNV insertion 20981092
nsv1041986 CNV gain 25217958
nsv1116459 OTHER inversion 24896259
nsv1153497 OTHER inversion 26484159
nsv1160094 CNV deletion 26073780
nsv442664 CNV loss 18776908
nsv964 CNV deletion 18451855
nsv977219 CNV duplication 23825009

Additional Variant Information for TPTE2P1 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
TPTE2P1

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for TPTE2P1 Gene

Disorders for TPTE2P1 Gene

Additional Disease Information for TPTE2P1

Genetic Association Database
(GAD)
ATLAS of Genetics and Cytogenetics in Oncology and Haematology

No disorders were found for TPTE2P1 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for TPTE2P1 Gene

Publications for TPTE2P1 Gene

  1. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T … Sugano S (Nature genetics 2004) 3 4 58
  2. Novel genetic loci identified for the pathophysiology of childhood obesity in the Hispanic population. (PMID: 23251661) Comuzzie AG … Butte NF (PloS one 2012) 3 58
  3. The DNA sequence and analysis of human chromosome 13. (PMID: 15057823) Dunham A … Ross MT (Nature 2004) 4 58

Products for TPTE2P1 Gene

Sources for TPTE2P1 Gene

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