Aliases for TPST2 Gene
External Ids for TPST2 Gene
Previous GeneCards Identifiers for TPST2 Gene
The protein encoded by this gene catalyzes the O-sulfation of tyrosine residues within acidic regions of proteins. The encoded protein is a type II integral membrane protein found in the Golgi body. Alternative splicing produces multiple transcript variants encoding distinct isoforms. [provided by RefSeq, May 2018]
GeneCards Summary for TPST2 Gene
TPST2 (Tyrosylprotein Sulfotransferase 2) is a Protein Coding gene. Gene Ontology (GO) annotations related to this gene include sulfotransferase activity and protein-tyrosine sulfotransferase activity. An important paralog of this gene is TPST1.
UniProtKB/Swiss-Prot Summary for TPST2 Gene
Catalyzes the O-sulfation of tyrosine residues within acidic motifs of polypeptides, using 3'-phosphoadenylyl sulfate (PAPS) as cosubstrate.