This gene encodes a mammalian peptidase that, at neutral pH, removes tripeptides from the N terminus of longer peptides. The protein has a specialized function that is essential for some MHC class I antigen presentation. The protein is a high molecular mass serine exopeptidase; the amino acid sequence surrounding the serine residue at the active site is similar to the peptidase... See more...

Aliases for TPP2 Gene

Aliases for TPP2 Gene

  • Tripeptidyl Peptidase 2 2 3 5
  • Tripeptidyl Aminopeptidase 3 4
  • Tripeptidyl-Peptidase II 3 4
  • Tripeptidyl-Peptidase 2 3 4
  • EC 3.4.14.10 4 51
  • TPP-II 3 4
  • TPP-2 3 4
  • TPPII 2 3
  • Tripeptidyl Peptidase II 2
  • TPP2 5

External Ids for TPP2 Gene

Previous GeneCards Identifiers for TPP2 Gene

  • GC13P101609
  • GC13P097636
  • GC13P102086
  • GC13P100947
  • GC13P102047
  • GC13P103249
  • GC13P083841

Summaries for TPP2 Gene

Entrez Gene Summary for TPP2 Gene

  • This gene encodes a mammalian peptidase that, at neutral pH, removes tripeptides from the N terminus of longer peptides. The protein has a specialized function that is essential for some MHC class I antigen presentation. The protein is a high molecular mass serine exopeptidase; the amino acid sequence surrounding the serine residue at the active site is similar to the peptidases of the subtilisin class rather than the trypsin class. [provided by RefSeq, Jul 2008]

GeneCards Summary for TPP2 Gene

TPP2 (Tripeptidyl Peptidase 2) is a Protein Coding gene. Diseases associated with TPP2 include Autoimmune Hemolytic Anemia-Autoimmune Thrombocytopenia-Primary Immunodeficiency Syndrome and Evans' Syndrome. Among its related pathways are Innate Immune System and Class I MHC mediated antigen processing and presentation. Gene Ontology (GO) annotations related to this gene include serine-type endopeptidase activity and peptide binding. An important paralog of this gene is MBTPS1.

UniProtKB/Swiss-Prot Summary for TPP2 Gene

  • Component of the proteolytic cascade acting downstream of the 26S proteasome in the ubiquitin-proteasome pathway. May be able to complement the 26S proteasome function to some extent under conditions in which the latter is inhibited. Stimulates adipogenesis (By similarity).

Gene Wiki entry for TPP2 Gene

No data available for CIViC Summary , Tocris Summary , PharmGKB "VIP" Summary , Rfam classification and piRNA Summary for TPP2 Gene

Genomics for TPP2 Gene

GeneHancer (GH) Regulatory Elements Pubs

Promoters and enhancers for TPP2 Gene
GeneHancer (GH) Identifier GH Type GH
Score
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH13J102593 Promoter/Enhancer 2.4 EPDnew FANTOM5 Ensembl ENCODE CraniofacialAtlas dbSUPER 261.6 -0.2 -224 6.3 ZSCAN16 TBP ZBTB10 SP1 MXD4 FEZF1 NR2C1 DEK IKZF1 SMAD5 TPP2 ENSG00000276957 LOC107984588 ENSG00000231633 CCDC168 ERCC5 METTL21C LINC00555 FGF14
GH13J102772 Promoter/Enhancer 1.9 EPDnew Ensembl ENCODE CraniofacialAtlas 16.3 +176.3 176304 3.4 TBP CEBPA SMAD5 MBD2 POLR2A ZNF610 SIN3A FOXA2 MAX RXRA TEX30 lnc-CCDC168-1 piR-44000 ERCC5 TPP2 BIVM ENSG00000231633 METTL21EP lnc-BIVM-3 CCDC168
GH13J102495 Enhancer 0.4 Ensembl ENCODE 14.8 -101.4 -101384 1.2 ZNF274 ERCC5 TPP2 HMGB3P7 piR-32023-075 HSALNG0099023 HSALNG0099021 FGF14
GH13J102591 Promoter/Enhancer 2 FANTOM5 Ensembl ENCODE CraniofacialAtlas dbSUPER 2.9 -4.5 -4539 1.9 MNT CTCF THAP11 CEBPB SIN3A REST TRIM22 MAFF SAP130 ZNF341 ENSG00000231633 CCDC168 TPP2 ERCC5 ENSG00000276957 LINC00555 LOC107984588 FGF14
GH13J103004 Enhancer 0.3 ENCODE 14.7 +408.0 407977 1.6 ZNF274 ERCC5 TPP2 HSALNG0099060 HSALNG0099059 SLC10A2
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data from 2017 publication | Request up-to-date GeneHancer data (full dataset)

GeneHancers around TPP2 on the GeneHancer Hub at the UCSC Golden Path

Cistromic (ChIP-Seq) regulation report from SPP (The Signaling Pathways Project) for TPP2

Top Transcription factor binding sites by QIAGEN in the TPP2 gene promoter:
  • AhR
  • AP-2gamma
  • c-Ets-1
  • Evi-1
  • FOXO1
  • FOXO1a
  • NRF-2
  • Pax-6

Genomic Locations for TPP2 Gene

Latest Assembly
chr13:102,596,985-102,679,958
(GRCh38/hg38)
Size:
82,974 bases
Orientation:
Plus strand

Previous Assembly
chr13:103,249,336-103,332,308
(GRCh37/hg19 by Entrez Gene)
Size:
82,973 bases
Orientation:
Plus strand

chr13:103,249,353-103,331,521
(GRCh37/hg19 by Ensembl)
Size:
82,169 bases
Orientation:
Plus strand

Genomic View for TPP2 Gene

Genes around TPP2 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
TPP2 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for TPP2 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for TPP2 Gene

Proteins for TPP2 Gene

  • Protein details for TPP2 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    P29144-TPP2_HUMAN
    Recommended name:
    Tripeptidyl-peptidase 2
    Protein Accession:
    P29144
    Secondary Accessions:
    • Q5VZU8

    Protein attributes for TPP2 Gene

    Size:
    1249 amino acids
    Molecular mass:
    138350 Da
    Quaternary structure:
    No Data Available
    Miscellaneous:
    • The limitation of proteolytic products to tripeptides is achieved by tailoring the size of the substrate-binding cleft: the two negatively charged residues Glu-305 and Glu-331 that are blocking position P4 limit the number of residues that can be accommodated in the binding cleft and thus create a molecular ruler. At the same time, they orient substrates so that the tripeptides are removed exclusively from the N-terminus (By similarity).

neXtProt entry for TPP2 Gene

Selected DME Specific Peptides for TPP2 Gene

P29144:
  • VLRNYKEAQEY
  • AANAVISHIDQTALAVYIAMKTDPRPDAA
  • SQANKLIKEEL
  • NIRVDPRGLREGLHYTEVCGYDIASPNAGPLFRVPITAVI
  • KLVEEKP
  • LDTGVDPGAPG
  • QLMNGTSM
  • SFHGIVCTAPQLNIH
  • SQVELLNSFEKKYSDPGPVYDCLVW
  • VSSAGNNGP
  • APGGAIASVP

Post-translational modifications for TPP2 Gene

  • Ubiquitination at Lys19, Lys1180, and Lys1187
  • Modification sites at PhosphoSitePlus

Domains & Families for TPP2 Gene

Gene Families for TPP2 Gene

Human Protein Atlas (HPA):
  • Enzymes
  • Plasma proteins
  • Predicted intracellular proteins

Protein Domains for TPP2 Gene

Suggested Antigen Peptide Sequences for TPP2 Gene

GenScript: Design optimal peptide antigens:
  • Tripeptidyl-peptidase II (TPP2_HUMAN)

Graphical View of Domain Structure for InterPro Entry

P29144

UniProtKB/Swiss-Prot:

TPP2_HUMAN :
  • Belongs to the peptidase S8 family.
Family:
  • Belongs to the peptidase S8 family.
genes like me logo Genes that share domains with TPP2: view

Function for TPP2 Gene

Molecular function for TPP2 Gene

UniProtKB/Swiss-Prot Function:
Component of the proteolytic cascade acting downstream of the 26S proteasome in the ubiquitin-proteasome pathway. May be able to complement the 26S proteasome function to some extent under conditions in which the latter is inhibited. Stimulates adipogenesis (By similarity).
UniProtKB/Swiss-Prot CatalyticActivity:
Reaction=Release of an N-terminal tripeptide from a polypeptide.; EC=3.4.14.10; Evidence={ECO:0000255|PROSITE-ProRule:PRU10081, ECO:0000255|PROSITE-ProRule:PRU10082};.
GENATLAS Biochemistry:
tripeptidyl peptidase 2

Enzyme Numbers (IUBMB) for TPP2 Gene

Phenotypes From GWAS Catalog for TPP2 Gene

Gene Ontology (GO) - Molecular Function for TPP2 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0004175 endopeptidase activity TAS 9974389
GO:0004177 aminopeptidase activity IEA --
GO:0004252 serine-type endopeptidase activity IEA --
GO:0005515 protein binding IPI 25416956
GO:0008233 peptidase activity IEA --
genes like me logo Genes that share ontologies with TPP2: view
genes like me logo Genes that share phenotypes with TPP2: view

Human Phenotype Ontology for TPP2 Gene

HPO Id HPO Name Alternative Ids Definition Synonyms

Animal Models for TPP2 Gene

MGI Knock Outs for TPP2:
  • Tpp2 Tpp2<tm1.1Gnie>

miRNA for TPP2 Gene

miRTarBase miRNAs that target TPP2

Inhibitory RNAs for research

  • Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for TPP2

No data available for Transcription Factor Targets and HOMER Transcription for TPP2 Gene

Localization for TPP2 Gene

Subcellular locations from UniProtKB/Swiss-Prot for TPP2 Gene

Cytoplasm. Nucleus. Note=Translocates to the nucleus in responce to gamma-irradiation.

Subcellular locations from

COMPARTMENTS
Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for TPP2 gene
Compartment Confidence
nucleus 5
cytosol 5
endoplasmic reticulum 2
lysosome 2
plasma membrane 1
extracellular 1
cytoskeleton 1
mitochondrion 1
endosome 1
golgi apparatus 1

Subcellular locations from the

Human Protein Atlas (HPA)
  • Cytosol (3)
  • Nuclear bodies (3)
See all subcellular structures

Gene Ontology (GO) - Cellular Components for TPP2 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005634 nucleus IEA --
GO:0005654 nucleoplasm IDA --
GO:0005737 cytoplasm TAS 9974389
GO:0005829 cytosol TAS --
GO:0016604 nuclear body IDA --
genes like me logo Genes that share ontologies with TPP2: view

Pathways & Interactions for TPP2 Gene

genes like me logo Genes that share pathways with TPP2: view

Pathways by source for TPP2 Gene

Gene Ontology (GO) - Biological Process for TPP2 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0000209 protein polyubiquitination TAS --
GO:0006508 proteolysis IEA --
genes like me logo Genes that share ontologies with TPP2: view

No data available for SIGNOR curated interactions for TPP2 Gene

Drugs & Compounds for TPP2 Gene

(1) Drugs for TPP2 Gene - From: Novoseek

Name Status Disease Links Group Role Mechanism of Action Clinical Trials

(2) Additional Compounds for TPP2 Gene - From: Novoseek

Name Synonyms Role CAS Number PubChem IDs PubMed IDs
genes like me logo Genes that share compounds with TPP2: view

Transcripts for TPP2 Gene

mRNA/cDNA for TPP2 Gene

3 REFSEQ mRNAs :
14 NCBI additional mRNA sequence :
17 Ensembl transcripts including schematic representations, and UCSC links to gene/alias where relevant :

Inhibitory RNAs for research

  • Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for TPP2

Alternative Splicing Database (ASD) splice patterns (SP) for TPP2 Gene

ExUns: 1a · 1b ^ 2 ^ 3 ^ 4 ^ 5 ^ 6 ^ 7 ^ 8 ^ 9 ^ 10a · 10b · 10c ^ 11a · 11b ^ 12 ^ 13 ^ 14 ^ 15 ^ 16 ^ 17 ^ 18 ^ 19a · 19b ^ 20 ^ 21a ·
SP1: - -
SP2: -
SP3: -
SP4: -
SP5: - -
SP6: - - - -
SP7: - - -
SP8: - - -
SP9:
SP10:
SP11:

ExUns: 21b ^ 22a · 22b · 22c ^ 23a · 23b
SP1:
SP2:
SP3:
SP4:
SP5:
SP6:
SP7:
SP8:
SP9:
SP10:
SP11:

Relevant External Links for TPP2 Gene

GeneLoc Exon Structure for
TPP2

Expression for TPP2 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and SAGE for TPP2 Gene

Protein differential expression in normal tissues from HIPED for TPP2 Gene

This gene is overexpressed in Peripheral blood mononuclear cells (10.4), Lymph node (9.7), and Retina (8.2).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, MaxQB, and MOPED for TPP2 Gene



Protein tissue co-expression partners for TPP2 Gene

- Elite partner

Transcriptomic regulation report from SPP (The Signaling Pathways Project) for TPP2

SOURCE GeneReport for Unigene cluster for TPP2 Gene:

Hs.432424

Evidence on tissue expression from TISSUES for TPP2 Gene

  • Liver(4.7)
  • Blood(4.7)
  • Nervous system(3.6)
  • Heart(2.9)
  • Eye(2.8)
  • Spleen(2.2)
  • Lymph node(2.1)
  • Muscle(2.1)
  • Lung(2)
  • Kidney(2)
  • Skin(2)
genes like me logo Genes that share expression patterns with TPP2: view

Primer products for research

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , mRNA Expression by UniProt/SwissProt and Phenotype-based relationships between genes and organs from Gene ORGANizer for TPP2 Gene

Orthologs for TPP2 Gene

This gene was present in the common ancestor of eukaryotes.

Orthologs for TPP2 Gene

Organism Taxonomy Gene Similarity Type Details
Chimpanzee
(Pan troglodytes)
Mammalia TPP2 30 31
  • 99.52 (n)
OneToOne
Dog
(Canis familiaris)
Mammalia TPP2 30 31
  • 92.82 (n)
OneToOne
Rat
(Rattus norvegicus)
Mammalia Tpp2 30
  • 90.77 (n)
Mouse
(Mus musculus)
Mammalia Tpp2 30 17 31
  • 90.37 (n)
OneToOne
Platypus
(Ornithorhynchus anatinus)
Mammalia TPP2 31
  • 90 (a)
OneToOne
Cow
(Bos Taurus)
Mammalia TPP2 30 31
  • 87.86 (n)
OneToOne
Oppossum
(Monodelphis domestica)
Mammalia TPP2 31
  • 87 (a)
OneToOne
Chicken
(Gallus gallus)
Aves TPP2 30 31
  • 81.33 (n)
OneToOne
Lizard
(Anolis carolinensis)
Reptilia TPP2 31
  • 83 (a)
OneToOne
Tropical Clawed Frog
(Silurana tropicalis)
Amphibia tpp2 30
  • 75.45 (n)
African clawed frog
(Xenopus laevis)
Amphibia Xl.20720 30
Zebrafish
(Danio rerio)
Actinopterygii TPP2 31
  • 74 (a)
OneToOne
tpp2 30
  • 66.27 (n)
African malaria mosquito
(Anopheles gambiae)
Insecta AgaP_AGAP004870 30
  • 49.26 (n)
Fruit Fly
(Drosophila melanogaster)
Insecta TppII 30 31 32
  • 48.47 (n)
OneToOne
Worm
(Caenorhabditis elegans)
Secernentea F21H12.6 30 32
  • 48.61 (n)
tpp-2 31
  • 33 (a)
OneToOne
Thale Cress
(Arabidopsis thaliana)
eudicotyledons TPP2 30
  • 49.78 (n)
Rice
(Oryza sativa)
Liliopsida Os02g0664300 30
  • 51 (n)
Os.27950 30
Sea Squirt
(Ciona savignyi)
Ascidiacea -- 31
  • 50 (a)
OneToOne
Fission Yeast
(Schizosaccharomyces pombe)
Schizosaccharomycetes tpp2 30
  • 48.41 (n)
Sea Vase
(Ciona intestinalis)
Ascidiacea Cin.14849 30
Species where no ortholog for TPP2 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Eremothecium gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • Alicante grape (Vitis vinifera)
  • Alpha proteobacteria (Wolbachia pipientis)
  • Amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • Baker's yeast (Saccharomyces cerevisiae)
  • Barley (Hordeum vulgare)
  • Beta proteobacteria (Neisseria meningitidis)
  • Bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • Common water flea (Daphnia pulex)
  • Corn (Zea mays)
  • E. coli (Escherichia coli)
  • Filamentous fungi (Aspergillus nidulans)
  • Firmicute Bacteria (Streptococcus pneumoniae)
  • Green Algae (Chlamydomonas reinhardtii)
  • Honey Bee (Apis mellifera)
  • K. Lactis Yeast (Kluyveromyces lactis)
  • Loblloly Pine (Pinus taeda)
  • Malaria Parasite (Plasmodium falciparum)
  • Medicago Trunc (Medicago Truncatula)
  • Moss (Physcomitrella patens)
  • Orangutan (Pongo pygmaeus)
  • Pig (Sus scrofa)
  • Rainbow Trout (Oncorhynchus mykiss)
  • Rice Blast Fungus (Magnaporthe grisea)
  • Schistosome Parasite (Schistosoma mansoni)
  • Sea Anemone (Nematostella vectensis)
  • Sea Urchin (Strongylocentrotus purpuratus)
  • Sorghum (Sorghum bicolor)
  • Soybean (Glycine max)
  • Stem Rust Fungus (Puccinia graminis)
  • Sugarcane (Saccharum officinarum)
  • Tomato (Lycopersicon esculentum)
  • Toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • Wheat (Triticum aestivum)

Evolution for TPP2 Gene

ENSEMBL:
Gene Tree for TPP2 (if available)
TreeFam:
Gene Tree for TPP2 (if available)
Aminode:
Evolutionary constrained regions (ECRs) for TPP2: view image

Paralogs for TPP2 Gene

Paralogs for TPP2 Gene

genes like me logo Genes that share paralogs with TPP2: view

Variants for TPP2 Gene

Sequence variations, with clinical significance, from ClinVar and Humsavar, with links to dbSNP for TPP2 Gene

SNP ID Clinical significance and condition Chr 13 pos Variation AA Info Type
834964 Uncertain Significance: Evans syndrome, immunodeficiency, and premature immunosenescence associated with tripeptidyl-peptidase II deficiency 102,627,107(+) A/G
NM_001330588.2(TPP2):c.880A>G (p.Ile294Val)
MISSENSE_VARIANT,NON_CODING_TRANSCRIPT
835267 Uncertain Significance: Evans syndrome, immunodeficiency, and premature immunosenescence associated with tripeptidyl-peptidase II deficiency 102,674,455(+) G/A
NM_001330588.2(TPP2):c.3544G>A (p.Glu1182Lys)
MISSENSE_VARIANT,NON_CODING_TRANSCRIPT
836223 Uncertain Significance: Evans syndrome, immunodeficiency, and premature immunosenescence associated with tripeptidyl-peptidase II deficiency 102,664,903(+) C/A
NM_001330588.2(TPP2):c.3349C>A (p.Pro1117Thr)
MISSENSE_VARIANT,NON_CODING_TRANSCRIPT
838567 Uncertain Significance: Evans syndrome, immunodeficiency, and premature immunosenescence associated with tripeptidyl-peptidase II deficiency 102,627,917(+) A/G
NM_001330588.2(TPP2):c.1009A>G (p.Asn337Asp)
MISSENSE_VARIANT,NON_CODING_TRANSCRIPT
839551 Uncertain Significance: Evans syndrome, immunodeficiency, and premature immunosenescence associated with tripeptidyl-peptidase II deficiency 102,618,794(+) G/A
NM_001330588.2(TPP2):c.568G>A (p.Asp190Asn)
MISSENSE_VARIANT,NON_CODING_TRANSCRIPT

dbSNP identifiers (rs#s) for variants without ClinVar clinical significance for TPP2 Gene

All consequence types are included: molecular consequences (e.g. missense, synonymous), and location-based (e.g. intron, upstream).

Structural Variations from Database of Genomic Variants (DGV) for TPP2 Gene

Variant ID Type Subtype PubMed ID
esv2306897 CNV deletion 18987734
esv2747910 CNV deletion 23290073
esv2747911 CNV deletion 23290073
esv3580867 CNV loss 25503493
nsv473907 CNV novel sequence insertion 20440878
nsv476294 CNV novel sequence insertion 20440878
nsv480645 CNV novel sequence insertion 20440878
nsv562980 CNV loss 21841781
nsv976263 CNV duplication 23825009

Variation tolerance for TPP2 Gene

Residual Variation Intolerance Score: 5.24% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 2.04; 37.46% of all genes are more intolerant (likely to be disease-causing)

Additional Variant Information for TPP2 Gene

Human Gene Mutation Database (HGMD)
TPP2
SNPedia medical, phenotypic, and genealogical associations of SNPs for
TPP2

SNP Genotyping and Copy Number Assays for research

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for TPP2 Gene

Disorders for TPP2 Gene

MalaCards: The human disease database

(4) MalaCards diseases for TPP2 Gene - From: ORP, COP, and GCD

Disorder Aliases PubMed IDs
autoimmune hemolytic anemia-autoimmune thrombocytopenia-primary immunodeficiency syndrome
  • evans syndrome associated with primary immunodeficiency
evans' syndrome
  • evan's syndrome
combined oxidative phosphorylation deficiency 23
  • coxpd23
burkitt lymphoma
  • bl
- elite association - COSMIC cancer census association via MalaCards
Search TPP2 in MalaCards View complete list of genes associated with diseases

Additional Disease Information for TPP2

Genetic Association Database
(GAD)
Human Genome Epidemiology Navigator
(HuGE)
Atlas
ATLAS of Genetics and Cytogenetics in Oncology and Haematology
Open Targets Platform
Open Targets Platform
genes like me logo Genes that share disorders with TPP2: view

No data available for UniProtKB/Swiss-Prot and Genatlas for TPP2 Gene

Publications for TPP2 Gene

  1. Characterization of cDNA for human tripeptidyl peptidase II: the N-terminal part of the enzyme is similar to subtilisin. (PMID: 1670990) Tomkinson B … Jonsson AK (Biochemistry 1991) 2 3 4 23
  2. Nucleotide sequence of cDNA covering the N-terminus of human tripeptidyl peptidase II. (PMID: 1840501) Tomkinson B (Biomedica biochimica acta 1991) 3 4 23
  3. Immunological cross-reactivity between human tripeptidyl peptidase II and fibronectin. (PMID: 1691635) Tomkinson B … Zetterqvist O (The Biochemical journal 1990) 3 4 23
  4. Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. (PMID: 20379614) Rose JE … Uhl GR (Molecular medicine (Cambridge, Mass.) 2010) 3 41
  5. A role for nuclear translocation of tripeptidyl-peptidase II in reactive oxygen species-dependent DNA damage responses. (PMID: 19747897) Preta G … Glas R (Biochemical and biophysical research communications 2009) 4 23

Products for TPP2 Gene

Sources for TPP2 Gene