Aliases for TP53TG3B Gene

Aliases for TP53TG3B Gene

  • TP53 Target 3B 2 3 5
  • TP53-Inducible Gene 3 Protein 3 4
  • TP53-Target Gene 3 Protein 3 4
  • TP53TG3E 3
  • TP53TG3F 3
  • TP53TG3B 5
  • TP53TG3A 4

External Ids for TP53TG3B Gene

Previous GeneCards Identifiers for TP53TG3B Gene

  • GC16P033170
  • GC16P033260

Summaries for TP53TG3B Gene

GeneCards Summary for TP53TG3B Gene

TP53TG3B (TP53 Target 3B) is a Protein Coding gene. Diseases associated with TP53TG3B include Reflex Epilepsy. An important paralog of this gene is LOC102723713.

UniProtKB/Swiss-Prot Summary for TP53TG3B Gene

Additional gene information for TP53TG3B Gene

No data available for Entrez Gene Summary , CIViC Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , Rfam classification and piRNA Summary for TP53TG3B Gene

Genomics for TP53TG3B Gene

GeneHancer (GH) Regulatory Elements Pubs

Promoters and enhancers for TP53TG3B Gene
GeneHancer (GH) Identifier GH Type GH
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH16J033360 Promoter 0.7 EPDnew Ensembl 250.7 +1.0 1027 1.4 TP53TG3B NONHSAG019235.2-003 piR-43901-005 piR-44170-005 LOC105379473 LOC105369266
GH16J033304 Promoter 0.7 EPDnew Ensembl 0.2 -55.5 -55473 1.6 ENSG00000260419-001 TP53TG3E NONHSAG019235.2-002 piR-43901-004 ENSG00000261507 TP53TG3B LOC105369266
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data from 2017 publication | Request up-to-date GeneHancer data (full dataset)

GeneHancers around TP53TG3B on the GeneHancer Hub at the UCSC Golden Path

Cistromic (ChIP-Seq) regulation report from SPP (The Signaling Pathways Project) for TP53TG3B

Genomic Locations for TP53TG3B Gene

Latest Assembly
3,214 bases
Plus strand

Previous Assembly
(GRCh37/hg19 by Entrez Gene)
2,611 bases
Plus strand

(GRCh37/hg19 by Ensembl)
3,202 bases
Plus strand

Genomic View for TP53TG3B Gene

Genes around TP53TG3B on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
TP53TG3B Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for TP53TG3B Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for TP53TG3B Gene

Proteins for TP53TG3B Gene

  • Protein details for TP53TG3B Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    TP53-target gene 3 protein
    Protein Accession:
    Secondary Accessions:
    • B2R5K6
    • Q4KN31
    • Q9ULY9

    Protein attributes for TP53TG3B Gene

    124 amino acids
    Molecular mass:
    12828 Da
    Quaternary structure:
    No Data Available
    • [Isoform 1]: May be produced at very low levels due to a premature stop codon in the mRNA, leading to nonsense-mediated mRNA decay.

    Alternative splice isoforms for TP53TG3B Gene


neXtProt entry for TP53TG3B Gene

Post-translational modifications for TP53TG3B Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for TP53TG3B Gene

No data available for DME Specific Peptides for TP53TG3B Gene

Domains & Families for TP53TG3B Gene

Gene Families for TP53TG3B Gene

Human Protein Atlas (HPA):
  • Predicted intracellular proteins
genes like me logo Genes that share domains with TP53TG3B: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences , Graphical View of Domain Structure and UniProtKB/Swiss-Prot for TP53TG3B Gene

Function for TP53TG3B Gene

Molecular function for TP53TG3B Gene

UniProtKB/Swiss-Prot Function:
May play a significant role in p53/TP53-mediating signaling pathway.
UniProtKB/Swiss-Prot Induction:
By p53/TP53.

Phenotypes From GWAS Catalog for TP53TG3B Gene

Inhibitory RNAs for research

  • Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for TP53TG3B

No data available for Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for TP53TG3B Gene

Localization for TP53TG3B Gene

Subcellular locations from UniProtKB/Swiss-Prot for TP53TG3B Gene

Cytoplasm. Nucleus.

Subcellular locations from

Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for TP53TG3B gene
Compartment Confidence
nucleus 5

Subcellular locations from the

Human Protein Atlas (HPA)
  • Centriolar satellite (2)
See all subcellular structures

Gene Ontology (GO) - Cellular Components for TP53TG3B Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005634 nucleus IEA,IDA 10534768
GO:0005737 cytoplasm IEA,IDA 10534768
genes like me logo Genes that share ontologies with TP53TG3B: view

Pathways & Interactions for TP53TG3B Gene

PathCards logo

SuperPathways for TP53TG3B Gene

No Data Available

Interacting Proteins for TP53TG3B Gene

Selected Interacting proteins: Q9ULZ0-T53G3_HUMAN for TP53TG3B Gene via IID

Symbol External ID(s) Details

Gene Ontology (GO) - Biological Process for TP53TG3B Gene


No data available for Pathways by source and SIGNOR curated interactions for TP53TG3B Gene

Drugs & Compounds for TP53TG3B Gene

No Compound Related Data Available

Transcripts for TP53TG3B Gene

mRNA/cDNA for TP53TG3B Gene

7 NCBI additional mRNA sequence :
5 Ensembl transcripts including schematic representations, and UCSC links to gene/alias where relevant :

Inhibitory RNAs for research

  • Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for TP53TG3B

Alternative Splicing Database (ASD) splice patterns (SP) for TP53TG3B Gene

No ASD Table

Relevant External Links for TP53TG3B Gene

GeneLoc Exon Structure for

Expression for TP53TG3B Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and SAGE for TP53TG3B Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

  • Testis (Reproductive System)

mRNA differential expression in normal tissues according to GTEx for TP53TG3B Gene

This gene is overexpressed in Testis (x53.0).

Protein differential expression in normal tissues from HIPED for TP53TG3B Gene

This gene is overexpressed in Fetal testis (69.0).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB and MOPED for TP53TG3B Gene

Protein tissue co-expression partners for TP53TG3B Gene

- Elite partner

Transcriptomic regulation report from SPP (The Signaling Pathways Project) for TP53TG3B

SOURCE GeneReport for Unigene cluster for TP53TG3B Gene:


mRNA Expression by UniProt/SwissProt for TP53TG3B Gene:

Tissue specificity: Strongly expressed in testis. Weakly expressed in heart, placenta and skeletal muscle.

Evidence on tissue expression from TISSUES for TP53TG3B Gene

  • Nervous system(2.3)
genes like me logo Genes that share expression patterns with TP53TG3B: view

Primer products for research

No data available for Phenotype-based relationships between genes and organs from Gene ORGANizer for TP53TG3B Gene

Orthologs for TP53TG3B Gene

This gene was present in the common ancestor of human and chimp.

Orthologs for TP53TG3B Gene

Organism Taxonomy Gene Similarity Type Details
(Pan troglodytes)
Mammalia -- 30
  • 98 (a)
LOC749815 29
  • 97.55 (n)
Species where no ortholog for TP53TG3B was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Eremothecium gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • Alpha proteobacteria (Wolbachia pipientis)
  • Amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • Baker's yeast (Saccharomyces cerevisiae)
  • Barley (Hordeum vulgare)
  • Beta proteobacteria (Neisseria meningitidis)
  • Bread mold (Neurospora crassa)
  • Chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • Common water flea (Daphnia pulex)
  • Corn (Zea mays)
  • Cow (Bos Taurus)
  • Dog (Canis familiaris)
  • E. coli (Escherichia coli)
  • Filamentous fungi (Aspergillus nidulans)
  • Firmicute Bacteria (Streptococcus pneumoniae)
  • Fission Yeast (Schizosaccharomyces pombe)
  • Fruit Fly (Drosophila melanogaster)
  • Green Algae (Chlamydomonas reinhardtii)
  • Honey Bee (Apis mellifera)
  • K. Lactis Yeast (Kluyveromyces lactis)
  • Lizard (Anolis carolinensis)
  • Loblloly Pine (Pinus taeda)
  • Malaria Parasite (Plasmodium falciparum)
  • Medicago Trunc (Medicago Truncatula)
  • Moss (Physcomitrella patens)
  • Mouse (Mus musculus)
  • Oppossum (Monodelphis domestica)
  • Orangutan (Pongo pygmaeus)
  • Pig (Sus scrofa)
  • Platypus (Ornithorhynchus anatinus)
  • Rainbow Trout (Oncorhynchus mykiss)
  • Rat (Rattus norvegicus)
  • Rice (Oryza sativa)
  • Rice Blast Fungus (Magnaporthe grisea)
  • Schistosome Parasite (Schistosoma mansoni)
  • Sea Anemone (Nematostella vectensis)
  • Sea Vase (Ciona intestinalis)
  • Sea Squirt (Ciona savignyi)
  • Sea Urchin (Strongylocentrotus purpuratus)
  • Sorghum (Sorghum bicolor)
  • Soybean (Glycine max)
  • Stem Rust Fungus (Puccinia graminis)
  • Sugarcane (Saccharum officinarum)
  • Thale Cress (Arabidopsis thaliana)
  • Tomato (Lycopersicon esculentum)
  • Toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • Tropical Clawed Frog (Silurana tropicalis)
  • Wheat (Triticum aestivum)
  • Worm (Caenorhabditis elegans)
  • Zebrafish (Danio rerio)

Evolution for TP53TG3B Gene

Gene Tree for TP53TG3B (if available)
Gene Tree for TP53TG3B (if available)
Alliance of Genome Resources:
Additional Orthologs for TP53TG3B

Paralogs for TP53TG3B Gene

(2) SIMAP similar genes for TP53TG3B Gene using alignment to 1 proteins:

  • T53G3_HUMAN
genes like me logo Genes that share paralogs with TP53TG3B: view

Variants for TP53TG3B Gene

dbSNP identifiers (rs#s) for variants without ClinVar clinical significance for TP53TG3B Gene

All consequence types are included: molecular consequences (e.g. missense, synonymous), and location-based (e.g. intron, upstream).

Structural Variations from Database of Genomic Variants (DGV) for TP53TG3B Gene

Variant ID Type Subtype PubMed ID
dgv117n111 CNV deletion 26073780
dgv119n111 CNV duplication 26073780
dgv120n111 CNV duplication 26073780
dgv121n111 CNV duplication 26073780
dgv1557e59 CNV duplication 20981092
dgv2837n100 CNV loss 25217958
dgv2838n100 CNV gain 25217958
dgv2839n100 CNV gain 25217958
dgv2840n100 CNV gain 25217958
dgv2841n100 CNV loss 25217958
dgv2842n100 CNV loss 25217958
dgv2844n100 CNV gain+loss 25217958
dgv2847n100 CNV gain+loss 25217958
dgv2851n100 CNV gain 25217958
dgv2852n100 CNV gain+loss 25217958
dgv2854n100 CNV gain 25217958
dgv2858n100 CNV gain+loss 25217958
dgv2861n100 CNV loss 25217958
dgv2862n100 CNV loss 25217958
dgv2866n100 CNV gain+loss 25217958
dgv2867n100 CNV gain 25217958
dgv2868n100 CNV loss 25217958
dgv2869n100 CNV gain 25217958
dgv2870n100 CNV gain+loss 25217958
dgv2871n100 CNV gain 25217958
dgv2872n100 CNV gain+loss 25217958
dgv2873n100 CNV gain 25217958
dgv2874n100 CNV loss 25217958
dgv2875n100 CNV loss 25217958
dgv2876n100 CNV loss 25217958
dgv2877n100 CNV loss 25217958
dgv2882n100 CNV gain 25217958
dgv2884n100 CNV loss 25217958
dgv2891n100 CNV loss 25217958
dgv2892n100 CNV loss 25217958
dgv2893n100 CNV loss 25217958
dgv2896n100 CNV loss 25217958
dgv2897n100 CNV gain+loss 25217958
dgv2898n100 CNV gain 25217958
dgv2899n100 CNV loss 25217958
dgv2900n100 CNV gain 25217958
dgv2901n100 CNV gain+loss 25217958
dgv2902n100 CNV gain 25217958
dgv2903n100 CNV gain+loss 25217958
dgv2904n100 CNV loss 25217958
dgv2905n100 CNV gain 25217958
dgv336e201 CNV deletion 23290073
dgv491e199 CNV deletion 23128226
dgv4996n54 CNV gain 21841781
dgv5008n54 CNV loss 21841781
dgv5009n54 CNV loss 21841781
dgv5027n54 CNV loss 21841781
dgv5048n54 CNV loss 21841781
dgv5049n54 CNV gain 21841781
dgv50e203 CNV gain+loss 21179565
dgv814e212 CNV gain 25503493
dgv816e212 CNV loss 25503493
dgv817e212 CNV loss 25503493
dgv819e212 CNV loss 25503493
dgv820e212 CNV gain 25503493
dgv821e212 CNV gain 25503493
dgv822e212 CNV gain 25503493
dgv823e212 CNV loss 25503493
esv1011117 CNV gain 20482838
esv2421440 OTHER complex 20811451
esv24815 CNV gain+loss 19812545
esv2629091 CNV gain 19546169
esv27116 CNV gain+loss 19812545
esv2714201 CNV deletion 23290073
esv2714208 CNV deletion 23290073
esv2714223 CNV deletion 23290073
esv29952 CNV gain 18421352
esv33069 CNV loss 17666407
esv3365693 CNV duplication 20981092
esv3570542 CNV gain 25503493
esv3584927 CNV gain 24956385
esv3892840 CNV gain 25118596
esv3892841 CNV gain+loss 25118596
esv992951 CNV gain 20482838
nsv1055691 CNV loss 25217958
nsv1056035 CNV gain 25217958
nsv1057046 CNV gain+loss 25217958
nsv1057297 CNV gain 25217958
nsv1061657 CNV gain 25217958
nsv1062147 CNV gain 25217958
nsv1062513 CNV gain+loss 25217958
nsv1063376 CNV loss 25217958
nsv1064239 CNV loss 25217958
nsv1070762 CNV deletion 25765185
nsv1124737 CNV duplication 24896259
nsv1139655 CNV duplication 24896259
nsv1146300 CNV duplication 26484159
nsv1146576 CNV duplication 26484159
nsv1160392 CNV deletion 26073780
nsv1160394 OTHER complex 26073780
nsv1160395 CNV duplication 26073780
nsv1160406 CNV duplication 26073780
nsv1160412 OTHER complex 26073780
nsv1160413 CNV duplication 26073780
nsv1790 CNV deletion 18451855
nsv428325 CNV gain+loss 18775914
nsv433444 CNV gain 18776910
nsv436841 CNV insertion 17901297
nsv469892 CNV gain+loss 16826518
nsv471390 CNV gain 19718026
nsv471500 CNV gain 19718026
nsv471692 CNV gain+loss 15918152
nsv482194 CNV gain 20164927
nsv510684 CNV deletion 20534489
nsv511048 OTHER complex 20534489
nsv520222 CNV loss 19592680
nsv527583 CNV gain 19592680
nsv571834 CNV loss 21841781
nsv571835 CNV loss 21841781
nsv571869 CNV gain+loss 21841781
nsv572013 CNV gain 21841781
nsv572198 CNV loss 21841781
nsv572204 CNV loss 21841781
nsv572208 CNV loss 21841781
nsv572209 CNV loss 21841781
nsv7281 OTHER inversion 18451855
nsv7282 OTHER inversion 18451855
nsv821684 CNV gain 15273396
nsv833201 CNV gain+loss 17160897
nsv833202 CNV gain 17160897
nsv9439 CNV gain+loss 18304495
nsv952324 CNV duplication 24416366
nsv977969 CNV duplication 23825009
nsv978136 CNV duplication 23825009
nsv978137 CNV duplication 23825009

Additional Variant Information for TP53TG3B Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
Leiden Open Variation Database (LOVD)

SNP Genotyping and Copy Number Assays for research

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Sequence variations, with clinical significance, from ClinVar and Humsavar, with links to dbSNP and Variation tolerance for TP53TG3B Gene

Disorders for TP53TG3B Gene

MalaCards: The human disease database

(1) MalaCards diseases for TP53TG3B Gene - From: COP

Disorder Aliases PubMed IDs
reflex epilepsy
  • epilepsy, sensory-induced
- elite association - COSMIC cancer census association via MalaCards

Additional Disease Information for TP53TG3B

genes like me logo Genes that share disorders with TP53TG3B: view

No data available for UniProtKB/Swiss-Prot and Genatlas for TP53TG3B Gene

Publications for TP53TG3B Gene

  1. Isolation and characterization of a novel TP53-inducible gene, TP53TG3. (PMID: 10534768) Ng CC … Nakamura Y (Genes, chromosomes & cancer 1999) 3 4
  2. Novel genetic loci identified for the pathophysiology of childhood obesity in the Hispanic population. (PMID: 23251661) Comuzzie AG … Butte NF (PloS one 2012) 3
  3. The full-ORF clone resource of the German cDNA Consortium. (PMID: 17974005) Bechtel S … Schupp I (BMC genomics 2007) 4
  4. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard DS … MGC Project Team (Genome research 2004) 4
  5. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T … Sugano S (Nature genetics 2004) 4

Products for TP53TG3B Gene

Sources for TP53TG3B Gene