Aliases for TOX Gene
External Ids for TOX Gene
Previous GeneCards Identifiers for TOX Gene
The protein encoded by this gene contains a HMG box DNA binding domain. HMG boxes are found in many eukaryotic proteins involved in chromatin assembly, transcription and replication. This protein may function to regulate T-cell development.[provided by RefSeq, Apr 2009]
GeneCards Summary for TOX Gene
TOX (Thymocyte Selection Associated High Mobility Group Box) is a Protein Coding gene. Diseases associated with TOX include Cutaneous Diphtheria and Clostridium Difficile Colitis. Among its related pathways are Development and heterogeneity of the ILC family and Mesodermal Commitment Pathway. Gene Ontology (GO) annotations related to this gene include chromatin binding. An important paralog of this gene is TOX2.
UniProtKB/Swiss-Prot Summary for TOX Gene
May play a role in regulating T-cell development.