Aliases for TOR1B Gene
External Ids for TOR1B Gene
Previous GeneCards Identifiers for TOR1B Gene
The protein encoded by this gene is an ATPase found primarily in the endoplasmic reticulum and nuclear envelope. This gene has a highly-similar neighboring gene, TOR1A, that encodes a protein that is likely to interact in a complex with this protein. Finally, this protein may act as a chaperone and play a role in maintaining the integrity of the nuclear envelope and endoplasmic reticulum. Several transcript variants, some protein-coding and others non-protein coding, have been found for this gene. [provided by RefSeq, Dec 2015]
GeneCards Summary for TOR1B Gene
TOR1B (Torsin Family 1 Member B) is a Protein Coding gene. Diseases associated with TOR1B include Acute Endophthalmitis and Focal Dystonia. Among its related pathways are Clathrin-mediated endocytosis and Vesicle-mediated transport. Gene Ontology (GO) annotations related to this gene include ATPase activity. An important paralog of this gene is TOR1A.
UniProtKB/Swiss-Prot Summary for TOR1B Gene
May serve as a molecular chaperone assisting in the proper folding of secreted and/or membrane proteins. Plays a role in non-neural cells nuclear envelope and endoplasmic reticulum integrity. May have a redundant function with TOR1A in non-neural tissues.