Aliases for TOP1P2 Gene

Aliases for TOP1P2 Gene

  • DNA Topoisomerase I Pseudogene 2 2 3
  • Topoisomerase (DNA) I Pseudogene 2 2 3

External Ids for TOP1P2 Gene

Previous GeneCards Identifiers for TOP1P2 Gene

  • GC22U990045
  • GC22P023485
  • GC22P025160
  • GC22P008108

Summaries for TOP1P2 Gene

GeneCards Summary for TOP1P2 Gene

TOP1P2 (DNA Topoisomerase I Pseudogene 2) is a Pseudogene.

Additional gene information for TOP1P2 Gene

No data available for Entrez Gene Summary , CIViC Summary , UniProtKB/Swiss-Prot Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , Rfam classification and piRNA Summary for TOP1P2 Gene

Genomics for TOP1P2 Gene

GeneHancer (GH) Regulatory Elements for TOP1P2 Gene

Promoters and enhancers for TOP1P2 Gene
GeneHancer (GH) Identifier GH Type GH
Score
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH22J024764 Enhancer 0.3 Ensembl 750.6 +0.4 400 0.2 ZSCAN4 TOP1P2 lnc-SGSM1-2 PIWIL3
GH22J024765 Enhancer 0.2 Ensembl 750.6 -0.3 -300 0.4 TOP1P2 lnc-SGSM1-2 PIWIL3 lnc-GGT1-5
GH22J024726 Enhancer 1.4 Ensembl ENCODE CraniofacialAtlas 0.3 -34.5 -34500 7.2 FOXK2 SIX5 ZBTB6 RBPJ SMARCE1 TCF7L2 CTBP1 RUNX1 ZNF133 CC2D1A SMARCB1 SPECC1L ENSG00000273295 SNRPD3 ENSG00000272977 LRP5L CABIN1 ENSG00000272973 MIF-AS1 GGTLC4P
GH22J024760 Promoter/Enhancer 0.6 EPDnew Ensembl 0.6 -2.6 -2600 2.2 ZNF384 PIWIL3 TOP1P2 lnc-SGSM1-2 lnc-GGT1-5
GH22J024758 Enhancer 0.6 ENCODE 0.4 -6.1 -6132 0.2 CTCF CC2D1A RAD21 ARID2 REST TRIM22 RFX5 SMC3 CUX1 GATA3 TOP1P2 lnc-SGSM1-2 PIWIL3 lnc-GGT1-5
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data from 2017 publication | Request up-to-date GeneHancer data (full dataset)

GeneHancers around TOP1P2 on UCSC Golden Path with GeneCards custom track

Top Transcription factor binding sites by QIAGEN in the TOP1P2 gene promoter:
  • AML1a
  • COUP
  • COUP-TF
  • COUP-TF1
  • FOXO4
  • IRF-7A
  • NRSF form 1
  • NRSF form 2
  • Pbx1a
  • TBP

Genomic Locations for TOP1P2 Gene

Genomic Locations for TOP1P2 Gene
chr22:24,764,501-24,766,021
(GRCh38/hg38)
Size:
1,521 bases
Orientation:
Plus strand
chr22:25,160,468-25,161,988
(GRCh37/hg19)
Size:
1,521 bases
Orientation:
Plus strand

Genomic View for TOP1P2 Gene

Genes around TOP1P2 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
TOP1P2 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for TOP1P2 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for TOP1P2 Gene

Proteins for TOP1P2 Gene

Post-translational modifications for TOP1P2 Gene

No Post-translational modifications

No data available for DME Specific Peptides for TOP1P2 Gene

Domains & Families for TOP1P2 Gene

No data available for Gene Families , Protein Domains , Suggested Antigen Peptide Sequences , Graphical View of Domain Structure and UniProtKB/Swiss-Prot for TOP1P2 Gene

Function for TOP1P2 Gene

Molecular function for TOP1P2 Gene

GENATLAS Biochemistry:
DNA topoisomerase I,pseudogene 2

Phenotypes From GWAS Catalog for TOP1P2 Gene

Animal Model Products

CRISPR Products

miRNA for TOP1P2 Gene

miRTarBase miRNAs that target TOP1P2

No data available for Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for TOP1P2 Gene

Localization for TOP1P2 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for TOP1P2 Gene

Pathways & Interactions for TOP1P2 Gene

PathCards logo

SuperPathways for TOP1P2 Gene

No Data Available

Gene Ontology (GO) - Biological Process for TOP1P2 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for TOP1P2 Gene

Drugs & Compounds for TOP1P2 Gene

No Compound Related Data Available

Transcripts for TOP1P2 Gene

mRNA/cDNA for TOP1P2 Gene

(1) Additional mRNA sequences :
(2) Selected AceView cDNA sequences:

CRISPR Products

Alternative Splicing Database (ASD) splice patterns (SP) for TOP1P2 Gene

No ASD Table

Relevant External Links for TOP1P2 Gene

GeneLoc Exon Structure for
TOP1P2
ECgene alternative splicing isoforms for
TOP1P2

Expression for TOP1P2 Gene

NURSA nuclear receptor signaling pathways regulating expression of TOP1P2 Gene:

TOP1P2

SOURCE GeneReport for Unigene cluster for TOP1P2 Gene:

Hs.381281
No Expression Related Data Available

No data available for mRNA expression in normal human tissues , mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for TOP1P2 Gene

Orthologs for TOP1P2 Gene

No data available for Orthologs and Evolution for TOP1P2 Gene

Paralogs for TOP1P2 Gene

No data available for Paralogs for TOP1P2 Gene

Variants for TOP1P2 Gene

Sequence variations from dbSNP and Humsavar for TOP1P2 Gene

SNP ID Clin Chr 22 pos Variation AA Info Type
rs1002239918 -- 24,766,180(+) T/C downstream_transcript_variant
rs1004021721 -- 24,764,502(+) G/A/C non_coding_transcript_variant
rs1004686603 -- 24,764,205(+) G/A upstream_transcript_variant
rs1005206991 -- 24,764,129(+) G/A upstream_transcript_variant
rs1006176775 -- 24,762,851(+) G/T upstream_transcript_variant

Structural Variations from Database of Genomic Variants (DGV) for TOP1P2 Gene

Variant ID Type Subtype PubMed ID
nsv1110863 OTHER inversion 24896259
nsv7350 OTHER inversion 18451855
nsv962778 CNV duplication 23825009

Additional Variant Information for TOP1P2 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
TOP1P2

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for TOP1P2 Gene

Disorders for TOP1P2 Gene

Additional Disease Information for TOP1P2

No disorders were found for TOP1P2 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for TOP1P2 Gene

Publications for TOP1P2 Gene

  1. Genome-wide association study identifies three novel susceptibility loci for severe Acne vulgaris. (PMID: 24927181) Navarini AA … Barker JN (Nature communications 2014) 3 56
  2. Molecular structures of two human DNA topoisomerase I retrosequences. (PMID: 2170234) Yang GC … Richter A (Gene 1990) 3 56

Products for TOP1P2 Gene

Sources for TOP1P2 Gene