Aliases for TOP1P1 Gene

Aliases for TOP1P1 Gene

  • DNA Topoisomerase I Pseudogene 1 2 3
  • Topoisomerase (DNA) I Pseudogene 1 3

External Ids for TOP1P1 Gene

Previous GeneCards Identifiers for TOP1P1 Gene

  • GC01U990170
  • GC01P169574
  • GC01P171309
  • GC01P142530

Summaries for TOP1P1 Gene

GeneCards Summary for TOP1P1 Gene

TOP1P1 (DNA Topoisomerase I Pseudogene 1) is a Pseudogene.

Additional gene information for TOP1P1 Gene

No data available for Entrez Gene Summary , CIViC Summary , UniProtKB/Swiss-Prot Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , Rfam classification and piRNA Summary for TOP1P1 Gene

Genomics for TOP1P1 Gene

GeneHancer (GH) Regulatory Elements for TOP1P1 Gene

Promoters and enhancers for TOP1P1 Gene
GeneHancer (GH) Identifier GH Type GH
Score
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH01J171336 Enhancer 0.2 Ensembl 750.6 -1.7 -1695 0.8 TOP1P1 FMO4 NONHSAG003442.2
GH01J171313 Promoter/Enhancer 1.9 EPDnew Ensembl ENCODE CraniofacialAtlas 0.3 -24.7 -24658 1.9 ZBTB40 CTCF ATF1 CREB1 MIXL1 ZNF362 MYC CC2D1A NFYC ELF1 FMO4 NONHSAG003442.2 TOP1P1
GH01J171335 Enhancer 0.5 Ensembl 0.6 -2.7 -2695 0.4 SP1 RXRA FOXA2 YY1 HNF4A TOP1P1 NONHSAG003442.2 FMO4
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data from 2017 publication | Request up-to-date GeneHancer data (full dataset)

GeneHancers around TOP1P1 on UCSC Golden Path with GeneCards custom track

Top Transcription factor binding sites by QIAGEN in the TOP1P1 gene promoter:
  • AML1a
  • Evi-1
  • GATA-1
  • GATA-2
  • GATA-3
  • Nkx2-5
  • POU2F1
  • POU2F1a
  • YY1

Genomic Locations for TOP1P1 Gene

Genomic Locations for TOP1P1 Gene
chr1:171,338,896-171,341,326
(GRCh38/hg38)
Size:
2,431 bases
Orientation:
Plus strand
chr1:171,308,035-171,310,465
(GRCh37/hg19)
Size:
2,431 bases
Orientation:
Plus strand

Genomic View for TOP1P1 Gene

Genes around TOP1P1 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
TOP1P1 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for TOP1P1 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for TOP1P1 Gene

Proteins for TOP1P1 Gene

Post-translational modifications for TOP1P1 Gene

No Post-translational modifications

No data available for DME Specific Peptides for TOP1P1 Gene

Domains & Families for TOP1P1 Gene

No data available for Gene Families , Protein Domains , Suggested Antigen Peptide Sequences , Graphical View of Domain Structure and UniProtKB/Swiss-Prot for TOP1P1 Gene

Function for TOP1P1 Gene

Molecular function for TOP1P1 Gene

GENATLAS Biochemistry:
DNA topoisomerase I,pseudogene 1,with antisense RNA transcripts

Phenotypes From GWAS Catalog for TOP1P1 Gene

Animal Model Products

CRISPR Products

No data available for Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for TOP1P1 Gene

Localization for TOP1P1 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for TOP1P1 Gene

Pathways & Interactions for TOP1P1 Gene

PathCards logo

SuperPathways for TOP1P1 Gene

No Data Available

Gene Ontology (GO) - Biological Process for TOP1P1 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for TOP1P1 Gene

Drugs & Compounds for TOP1P1 Gene

No Compound Related Data Available

Transcripts for TOP1P1 Gene

mRNA/cDNA for TOP1P1 Gene

(1) Additional mRNA sequences :

CRISPR Products

Alternative Splicing Database (ASD) splice patterns (SP) for TOP1P1 Gene

No ASD Table

Relevant External Links for TOP1P1 Gene

GeneLoc Exon Structure for
TOP1P1
ECgene alternative splicing isoforms for
TOP1P1

Expression for TOP1P1 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for TOP1P1 Gene

mRNA expression in normal human tissues for TOP1P1 Gene

NURSA nuclear receptor signaling pathways regulating expression of TOP1P1 Gene:

TOP1P1

SOURCE GeneReport for Unigene cluster for TOP1P1 Gene:

Hs.661092
genes like me logo Genes that share expression patterns with TOP1P1: view

Primer Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for TOP1P1 Gene

Orthologs for TOP1P1 Gene

No data available for Orthologs and Evolution for TOP1P1 Gene

Paralogs for TOP1P1 Gene

No data available for Paralogs for TOP1P1 Gene

Variants for TOP1P1 Gene

Sequence variations from dbSNP and Humsavar for TOP1P1 Gene

SNP ID Clin Chr 01 pos Variation AA Info Type
rs1000319188 -- 171,338,499(+) C/T upstream_transcript_variant
rs1003089110 -- 171,339,813(+) G/A non_coding_transcript_variant
rs1003887760 -- 171,339,006(+) T/C non_coding_transcript_variant
rs1004257765 -- 171,339,369(+) C/T non_coding_transcript_variant
rs1004822728 -- 171,338,935(+) G/A non_coding_transcript_variant

Structural Variations from Database of Genomic Variants (DGV) for TOP1P1 Gene

Variant ID Type Subtype PubMed ID
esv28731 CNV gain+loss 19812545
nsv1002423 CNV loss 25217958
nsv548188 CNV loss 21841781
nsv831882 CNV loss 17160897
nsv946501 CNV duplication 23825009

Additional Variant Information for TOP1P1 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
TOP1P1

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for TOP1P1 Gene

Disorders for TOP1P1 Gene

Additional Disease Information for TOP1P1

No disorders were found for TOP1P1 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for TOP1P1 Gene

Publications for TOP1P1 Gene

  1. VIRMA mediates preferential m6A mRNA methylation in 3'UTR and near stop codon and associates with alternative polyadenylation. (PMID: 29507755) Yue Y … Liu J (Cell discovery 2018) 3 56
  2. Molecular structures of two human DNA topoisomerase I retrosequences. (PMID: 2170234) Yang GC … Richter A (Gene 1990) 3 56

Products for TOP1P1 Gene

Sources for TOP1P1 Gene