Aliases for TOM1 Gene
External Ids for TOM1 Gene
Previous GeneCards Identifiers for TOM1 Gene
This gene was identified as a target of the v-myb oncogene. The encoded protein shares its N-terminal domain in common with proteins associated with vesicular trafficking at the endosome. It is recruited to the endosomes by its interaction with endofin. Several alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2008]
GeneCards Summary for TOM1 Gene
TOM1 (Target Of Myb1 Membrane Trafficking Protein) is a Protein Coding gene. Diseases associated with TOM1 include Deafness, Autosomal Recessive 37 and Deafness, Autosomal Dominant 22. Among its related pathways are Innate Immune System and C-MYB transcription factor network. Gene Ontology (GO) annotations related to this gene include clathrin binding. An important paralog of this gene is TOM1L2.
UniProtKB/Swiss-Prot for TOM1 Gene
May be involved in intracellular trafficking. Probable association with membranes.