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Aliases for TNRC6C Gene
Aliases for TNRC6C Gene
External Ids for TNRC6C Gene
- HGNC: 29318
- Entrez Gene: 57690
- Ensembl: ENSG00000078687
- OMIM: 610741
- UniProtKB: Q9HCJ0
Previous GeneCards Identifiers for TNRC6C Gene
- GC17P073557
- GC17P076002
- GC17P071424
- GC17P078004
Summaries for TNRC6C Gene
GeneCards Summary for TNRC6C Gene
TNRC6C (Trinucleotide Repeat Containing Adaptor 6C) is a Protein Coding gene. Diseases associated with TNRC6C include Epidermodysplasia Verruciformis 1. Among its related pathways are RET signaling and Signaling by GPCR. Gene Ontology (GO) annotations related to this gene include RNA binding and nucleotide binding. An important paralog of this gene is TNRC6A.
UniProtKB/Swiss-Prot Summary for TNRC6C Gene
-
Plays a role in RNA-mediated gene silencing by micro-RNAs (miRNAs). Required for miRNA-dependent translational repression of complementary mRNAs by argonaute family proteins. As scaffoldng protein associates with argonaute proteins bound to partially complementary mRNAs and simultaneously can recruit CCR4-NOT and PAN deadenylase complexes.
Additional gene information for TNRC6C Gene
- HGNC(29318)
- Entrez Gene(57690)
- Ensembl(ENSG00000078687)
- OMIM(610741)
- UniProtKB(Q9HCJ0)
- Open Targets Platform(ENSG00000078687)
- Search for TNRC6C at DataMed
- Search for TNRC6C at HumanCyc
No data available for Entrez Gene Summary , CIViC Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , Rfam classification and piRNA Summary for TNRC6C Gene
Genomics for TNRC6C Gene
GeneHancer (GH) Regulatory Elements Pubs
Promoters and enhancers for TNRC6C Gene
- Elite GeneHancer and/or Elite GeneHancer-gene association
Download GeneHancer data from 2017 publication |
Request up-to-date GeneHancer data (full dataset)
GeneHancers around TNRC6C on the GeneHancer Hub at the UCSC Golden Path
Cistromic (ChIP-Seq) regulation report from SPP (The Signaling Pathways Project) for TNRC6C
- Top Transcription factor binding sites by QIAGEN in the TNRC6C gene promoter:
-
- AP-1
- c-Fos
- c-Jun
- Cart-1
- FosB
- Fra-1
- HNF-3beta
- JunB
- JunD
- STAT5A
Genomic Locations for TNRC6C Gene
Genomic Locations for TNRC6C Gene
- chr17:77,958,853-78,108,835
- (GRCh38/hg38)
- Size:
- 149,983 bases
- Orientation:
- Plus strand
- chr17:76,000,249-76,104,916
- (GRCh37/hg19)
- Size:
- 104,668 bases
- Orientation:
- Plus strand
Genomic View for TNRC6C Gene
Genes around TNRC6C on UCSC Golden Path with GeneCards custom track
- Cytogenetic band:
-
- 17q25.3 by HGNC
- 17q25.3 by Entrez Gene
- 17q25.3 by Ensembl
TNRC6C Gene in genomic location: bands according to
Ensembl, locations according to GeneLoc
(and/or Entrez Gene and/or Ensembl if different)
Genomic Neighborhood
• Exon Structure
• Gene Density
RefSeq DNA sequence for TNRC6C Gene
Proteins for TNRC6C Gene
-
Protein details for TNRC6C Gene (UniProtKB/Swiss-Prot)
- Protein Symbol:
- Q9HCJ0-TNR6C_HUMAN
- Recommended name:
- Trinucleotide repeat-containing gene 6C protein
- Protein Accession:
- Q9HCJ0
- G3XAB8
- Q86UE5
- Q8N3D8
- Q96MU9
Protein attributes for TNRC6C Gene
- Size:
- 1690 amino acids
- Molecular mass:
- 175964 Da
- Quaternary structure:
-
- Interacts with one or more of the argonaute family proteins AGO1, AGO2, AGO3 and AGO4. Interacts with PABPC1 and EIF4G1. Interacts with CNOT1; the interaction is direct and mediates the association with the CCR4-NOT complex. Interacts with PAN3; the interaction mediates the association with the PAN complex.
- SequenceCaution:
-
- Sequence=BAB13408.2; Type=Erroneous initiation; Note=Extended N-terminus.; Evidence={ECO:0000305}; Sequence=BAB71179.1; Type=Erroneous initiation; Note=Truncated N-terminus.; Evidence={ECO:0000305};
Protein Expression for TNRC6C Gene
Post-translational modifications for TNRC6C Gene
Other Protein References for TNRC6C Gene
Antibody Products
- Novus Biologicals Antibodies for TNRC6C
-
Abcam antibodies for TNRC6C
- Invitrogen Antibodies for TNRC6C (AFLGC-TNRC6C)
Protein Products
- Search Origene for Purified Proteins, MassSpec and Protein Over-expression Lysates for TNRC6C
- Origene Custom Protein Services for TNRC6C
- Novus Biologicals proteins for TNRC6C
Assay Products
-
Signalway ELISA kits for TNRC6C
No data available for DME Specific Peptides for TNRC6C Gene
Domains & Families for TNRC6C Gene
Gene Families for TNRC6C Gene
- HGNC:
- Human Protein Atlas (HPA):
-
- Predicted intracellular proteins
Protein Domains for TNRC6C Gene
- InterPro:
- Blocks:
-
- RNA-binding region RNP-1 (RNA recognition motif)
- ProtoNet:
Suggested Antigen Peptide Sequences for TNRC6C Gene
- GenScript: Design optimal peptide antigens:
-
- Trinucleotide repeat-containing gene 6C protein (TNR6C_HUMAN)
Graphical View of Domain Structure for InterPro Entry
Q9HCJ0UniProtKB/Swiss-Prot:
TNR6C_HUMAN :- The silencing domain, also known as C-terminal effector domain (CED), can act in autonomous repression, including both translational inhibition and mRNA degradation.
- Belongs to the GW182 family.
- Domain:
-
- The silencing domain, also known as C-terminal effector domain (CED), can act in autonomous repression, including both translational inhibition and mRNA degradation.
- Family:
-
- Belongs to the GW182 family.
Function for TNRC6C Gene
Molecular function for TNRC6C Gene
- UniProtKB/Swiss-Prot Function:
- Plays a role in RNA-mediated gene silencing by micro-RNAs (miRNAs). Required for miRNA-dependent translational repression of complementary mRNAs by argonaute family proteins. As scaffoldng protein associates with argonaute proteins bound to partially complementary mRNAs and simultaneously can recruit CCR4-NOT and PAN deadenylase complexes.
Phenotypes From GWAS Catalog for TNRC6C Gene
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0003676 | nucleic acid binding | IEA | -- |
| GO:0003723 | RNA binding | IEA | -- |
| GO:0005515 | protein binding | IPI | 19383768 |
Phenotypes for TNRC6C Gene
- MGI mutant phenotypes for TNRC6C:
- inferred from 1 alleles
- GenomeRNAi human phenotypes for TNRC6C:
Animal Model Products
- Taconic Biosciences: Generate A Custom CRISPR Mouse Model For Your Study
CRISPR Products
- Applied Biological Materials (abm): CRISPR Clones for TNRC6C - Select products 50% OFF >
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-
OriGene CRISPR knockouts for TNRC6C
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-
Santa Cruz Biotechnology (SCBT) CRISPR for TNRC6C
miRNA for TNRC6C Gene
- miRTarBase miRNAs that target TNRC6C
-
- mmu-miR-425-5p (MIRT008700)
- mmu-miR-26a-5p (MIRT011388)
- mmu-miR-30e-5p (MIRT013401)
- hsa-miR-30b-5p (MIRT023444)
- hsa-miR-4509 (MIRT078989)
- hsa-miR-4643 (MIRT079004)
- hsa-miR-95-5p (MIRT079019)
- hsa-miR-320a (MIRT079021)
- hsa-miR-331-5p (MIRT079022)
- hsa-miR-320b (MIRT079023)
- hsa-miR-320c (MIRT079024)
- hsa-miR-548m (MIRT079028)
- hsa-miR-320d (MIRT079029)
- hsa-miR-4429 (MIRT079030)
- hsa-miR-4666a-5p (MIRT079031)
- hsa-miR-125b-2-3p (MIRT079046)
- hsa-miR-380-3p (MIRT079048)
- hsa-miR-378a-5p (MIRT251876)
- hsa-miR-1200 (MIRT251878)
- hsa-miR-4666b (MIRT289287)
- hsa-miR-212-3p (MIRT289306)
- hsa-miR-132-3p (MIRT289307)
- hsa-miR-4709-5p (MIRT289309)
- hsa-miR-7159-5p (MIRT289310)
- mmu-miR-190a-5p (MIRT411759)
- mmu-miR-190b-5p (MIRT411764)
- mmu-miR-654-3p (MIRT411765)
- mmu-miR-5116 (MIRT411768)
- hsa-miR-1273e (MIRT448399)
- hsa-miR-580-3p (MIRT448400)
- hsa-miR-539-5p (MIRT448401)
- hsa-miR-4635 (MIRT448402)
- hsa-miR-1264 (MIRT448404)
- hsa-miR-7152-5p (MIRT546213)
- hsa-miR-3074-5p (MIRT546214)
- hsa-miR-5700 (MIRT546215)
- hsa-miR-6512-5p (MIRT553451)
- hsa-miR-548ay-3p (MIRT553452)
- hsa-miR-548at-3p (MIRT553453)
- hsa-miR-548as-3p (MIRT553454)
- hsa-miR-548t-3p (MIRT553455)
- hsa-miR-548ap-3p (MIRT553456)
- hsa-miR-548aa (MIRT553457)
- hsa-miR-629-3p (MIRT565266)
- hsa-miR-519e-5p (MIRT565267)
- hsa-miR-515-5p (MIRT565268)
- hsa-miR-3925-3p (MIRT565269)
- hsa-miR-766-3p (MIRT565270)
- mmu-miR-448-5p (MIRT580305)
- mmu-miR-692 (MIRT580306)
- hsa-miR-1305 (MIRT612348)
- hsa-miR-4652-3p (MIRT612349)
- hsa-miR-421 (MIRT612350)
- hsa-miR-505-3p (MIRT612351)
- hsa-miR-8064 (MIRT612352)
- hsa-miR-3182 (MIRT612353)
- hsa-miR-216b-3p (MIRT612354)
- hsa-miR-603 (MIRT612355)
- hsa-miR-8485 (MIRT612356)
- hsa-miR-5010-3p (MIRT652292)
- hsa-miR-1238-3p (MIRT652293)
- hsa-miR-670-3p (MIRT652294)
- hsa-miR-6844 (MIRT652295)
- hsa-miR-6881-3p (MIRT652296)
- hsa-miR-6780a-3p (MIRT652297)
- hsa-miR-7111-3p (MIRT652298)
- hsa-miR-877-3p (MIRT652299)
- hsa-miR-4677-5p (MIRT718209)
- hsa-miR-22-5p (MIRT718210)
- hsa-miR-2116-5p (MIRT718211)
- hsa-miR-676-5p (MIRT718212)
- hsa-miR-4659b-3p (MIRT723193)
- hsa-miR-4659a-3p (MIRT723194)
- hsa-miR-6875-3p (MIRT723195)
- hsa-miR-511-5p (MIRT723196)
- hsa-miR-502-5p (MIRT723197)
- hsa-miR-6830-3p (MIRT723198)
- hsa-miR-1915-5p (MIRT723199)
- hsa-miR-6841-3p (MIRT723200)
miRNA Products
Inhibitory RNA Products
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Clone Products
- Applied Biological Materials (abm): Clones for TNRC6C - Select products 50% OFF >
- * TNRC6C as ready-to-use vector or virus: ORF | Lenti- | Retro- | Adeno- | AAV- | Protein Vector - Browse All
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- Sino Biological Human cDNA Clone for TNRC6C
- Addgene plasmids for TNRC6C
- Search GeneCopoeia for ORF cDNA, lentivirus, AAV viral particles and/or promoter clone products for TNRC6C
Cell Line Products
-
Horizon Cell Lines for TNRC6C
No data available for Enzyme Numbers (IUBMB) , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for TNRC6C Gene
Localization for TNRC6C Gene
| Compartment | Confidence |
|---|---|
| nucleus | 4 |
| cytosol | 4 |
| extracellular | 1 |
| cytoskeleton | 1 |
| mitochondrion | 1 |
| endoplasmic reticulum | 1 |
| endosome | 1 |
- Nucleoplasm (2)
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0000932 | P-body | IBA | 21873635 |
| GO:0005654 | nucleoplasm | IBA | 21873635 |
| GO:0005829 | cytosol | TAS | -- |
No data available for Subcellular locations from UniProtKB/Swiss-Prot for TNRC6C Gene
Pathways & Interactions for TNRC6C Gene
| SuperPathway | Contained pathways | ||
|---|---|---|---|
| 1 | RET signaling |
.92
|
|
| 2 | GAB1 signalosome |
.89
|
|
| 3 | Regulation of activated PAK-2p34 by proteasome mediated degradation |
.41
|
|
| 4 | Cellular Senescence (REACTOME) | ||
| 5 | Pre-NOTCH Expression and Processing | ||
Pathways by source for TNRC6C Gene
1 BioSystems pathway for TNRC6C Gene
37 Reactome pathways for TNRC6C Gene
Interacting Proteins for TNRC6C Gene
Selected Interacting proteins:
Q9HCJ0-TNR6C_HUMAN
ENSP00000336783
for TNRC6C Gene via
UniProtKB
MINT
STRING
IID
GPS-Prot Interaction Network for TNRC6C
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0006417 | regulation of translation | IEA | -- |
| GO:0007223 | Wnt signaling pathway, calcium modulating pathway | TAS | -- |
| GO:0010628 | positive regulation of gene expression | TAS | -- |
| GO:0010629 | negative regulation of gene expression | TAS | -- |
| GO:0031047 | gene silencing by RNA | IEA | -- |
No data available for SIGNOR curated interactions for TNRC6C Gene
Transcripts for TNRC6C Gene
mRNA/cDNA for TNRC6C Gene
- 2 REFSEQ mRNAs :
- 14 NCBI additional mRNA sequence :
- 11 Ensembl transcripts including schematic representations, and UCSC links to gene/alias where relevant :
-
- ENST00000301624 9632 nts (view in UCSC)
- ENST00000335749 9740 nts (view in UCSC)
- ENST00000585438 682 nts (view in UCSC)
- ENST00000587990 600 nts (view in UCSC)
- ENST00000588061 8419 nts (view in UCSC)
CRISPR Products
- Applied Biological Materials (abm): CRISPR Clones for TNRC6C - Select products 50% OFF >
- * TNRC6C CRISPR as ready-to-use vector or virus: ORF | Lenti- | Adeno- | AAV- | Protein Vector - Browse All
- * Gene synthesis, site-directed mutagenesis, subcloning, and more services - Browse All
-
OriGene CRISPR knockouts for TNRC6C
- Search GeneCopoeia for CRISPR/Cas9 clones, lentivirus and AAV products for TNRC6C
-
Santa Cruz Biotechnology (SCBT) CRISPR for TNRC6C
miRNA Products
Inhibitory RNA Products
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Clone Products
- Applied Biological Materials (abm): Clones for TNRC6C - Select products 50% OFF >
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- Sino Biological Human cDNA Clone for TNRC6C
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| ExUns: | 1a | · | 1b | ^ | 2 | ^ | 3 | ^ | 4 | ^ | 5 | ^ | 6 | ^ | 7a | · | 7b | ^ | 8 | ^ | 9 | ^ | 10 | ^ | 11 | ^ | 12a | · | 12b | ^ | 13a | · | 13b | ^ | 14 | ^ | 15 | ^ | 16 | ^ | 17 | ^ | 18 | ^ | 19a | · | 19b |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| SP1: | - | - | - | - | |||||||||||||||||||||||||||||||||||||||||||
| SP2: | - | - | - | - | |||||||||||||||||||||||||||||||||||||||||||
| SP3: | - | ||||||||||||||||||||||||||||||||||||||||||||||
| SP4: |
Relevant External Links for TNRC6C Gene
- GeneLoc Exon Structure for
- TNRC6C
Expression for TNRC6C Gene
This gene is overexpressed in Breast (51.7) and Heart (11.2).
Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, MaxQB, and MOPED for TNRC6C Gene
Transcriptomic regulation report from SPP (The Signaling Pathways Project) for TNRC6C
SOURCE GeneReport for Unigene cluster for TNRC6C Gene:
Hs.569831Evidence on tissue expression from TISSUES for TNRC6C Gene
- Nervous system(4.7)
- Liver(4.4)
Primer Products
-
OriGene qPCR primer pairs for TNRC6C
Gene Expression Assay Products
No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt and Phenotype-based relationships between genes and organs from Gene ORGANizer for TNRC6C Gene
Orthologs for TNRC6C Gene
This gene was present in the common ancestor of animals.
| Organism | Taxonomy | Gene | Similarity | Type | Details |
|---|---|---|---|---|---|
| Chimpanzee (Pan troglodytes) |
Mammalia | TNRC6C 30 31 |
|
OneToOne | |
| Dog (Canis familiaris) |
Mammalia | TNRC6C 30 31 |
|
OneToOne | |
| Mouse (Mus musculus) |
Mammalia | Tnrc6c 30 17 31 |
|
OneToOne | |
| Rat (Rattus norvegicus) |
Mammalia | Tnrc6c 30 |
|
||
| Cow (Bos Taurus) |
Mammalia | TNRC6C 30 31 |
|
OneToOne | |
| Oppossum (Monodelphis domestica) |
Mammalia | TNRC6C 31 |
|
OneToOne | |
| Platypus (Ornithorhynchus anatinus) |
Mammalia | TNRC6C 31 |
|
OneToOne | |
| Chicken (Gallus gallus) |
Aves | TNRC6C 30 31 |
|
OneToOne | |
| Lizard (Anolis carolinensis) |
Reptilia | TNRC6C 31 |
|
OneToOne | |
| Tropical Clawed Frog (Silurana tropicalis) |
Amphibia | tnrc6c 30 |
|
||
| Zebrafish (Danio rerio) |
Actinopterygii | tnrc6c 30 |
|
||
| TNRC6C (2 of 5) 31 |
|
OneToMany | |||
| TNRC6C (4 of 5) 31 |
|
OneToMany | |||
| TNRC6C (5 of 5) 31 |
|
OneToMany | |||
| TNRC6C (3 of 5) 31 |
|
OneToMany | |||
| tnrc6b 31 |
|
OneToMany | |||
| Dr.12790 30 |
|
||||
| Fruit Fly (Drosophila melanogaster) |
Insecta | gw 31 |
|
OneToMany | |
| Sea Squirt (Ciona savignyi) |
Ascidiacea | -- 31 |
|
OneToMany |
- Species where no ortholog for TNRC6C was found in the sources mined by GeneCards:
-
- A. gosspyii yeast (Eremothecium gossypii)
- Actinobacteria (Mycobacterium tuberculosis)
- African clawed frog (Xenopus laevis)
- African malaria mosquito (Anopheles gambiae)
- Alicante grape (Vitis vinifera)
- Alpha proteobacteria (Wolbachia pipientis)
- Amoeba (Dictyostelium discoideum)
- Archea (Pyrococcus horikoshii)
- Baker's yeast (Saccharomyces cerevisiae)
- Barley (Hordeum vulgare)
- Beta proteobacteria (Neisseria meningitidis)
- Bread mold (Neurospora crassa)
- Chromalveolata (Phytophthora infestans)
- Common water flea (Daphnia pulex)
- Corn (Zea mays)
- E. coli (Escherichia coli)
- Filamentous fungi (Aspergillus nidulans)
- Firmicute Bacteria (Streptococcus pneumoniae)
- Fission Yeast (Schizosaccharomyces pombe)
- Green Algae (Chlamydomonas reinhardtii)
- Honey Bee (Apis mellifera)
- K. Lactis Yeast (Kluyveromyces lactis)
- Loblloly Pine (Pinus taeda)
- Malaria Parasite (Plasmodium falciparum)
- Medicago Trunc (Medicago Truncatula)
- Moss (Physcomitrella patens)
- Orangutan (Pongo pygmaeus)
- Pig (Sus scrofa)
- Rainbow Trout (Oncorhynchus mykiss)
- Rice (Oryza sativa)
- Rice Blast Fungus (Magnaporthe grisea)
- Schistosome Parasite (Schistosoma mansoni)
- Sea Anemone (Nematostella vectensis)
- Sea Vase (Ciona intestinalis)
- Sea Urchin (Strongylocentrotus purpuratus)
- Sorghum (Sorghum bicolor)
- Soybean (Glycine max)
- Stem Rust Fungus (Puccinia graminis)
- Sugarcane (Saccharum officinarum)
- Thale Cress (Arabidopsis thaliana)
- Tomato (Lycopersicon esculentum)
- Toxoplasmosis (Toxoplasma gondii)
- Trichoplax (Trichoplax adhaerens)
- Wheat (Triticum aestivum)
- Worm (Caenorhabditis elegans)
Evolution for TNRC6C Gene
- ENSEMBL:
- Gene Tree for TNRC6C (if available)
- TreeFam:
- Gene Tree for TNRC6C (if available)
- Aminode:
- Evolutionary constrained regions (ECRs) for TNRC6C: view image
Paralogs for TNRC6C Gene
Variants for TNRC6C Gene
Sequence variations, with clinical significance, from ClinVar and Humsavar, with links to dbSNP for TNRC6C Gene
| SNP ID | Clinical significance and condition | Chr 17 pos | Variation | AA Info | Type |
|---|---|---|---|---|---|
| 816806 | Uncertain Significance: Intellectual disability | 78,050,084(+) | G/A | MISSENSE_VARIANT | |
| rs34293811 | - | p.Pro820Arg |
| Variant ID | Type | Subtype | PubMed ID |
|---|---|---|---|
| dgv570e199 | CNV | deletion | 23128226 |
| esv3641322 | CNV | loss | 21293372 |
| esv3641323 | CNV | loss | 21293372 |
| nsv1064772 | CNV | gain | 25217958 |
| nsv2153 | CNV | deletion | 18451855 |
| nsv833554 | CNV | gain+loss | 17160897 |
Residual Variation Intolerance Score:
3.2% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score:
6.89;
79.56% of all genes are more intolerant (likely to be disease-causing)
Additional Variant Information for TNRC6C Gene
SNP Genotyping and Copy Number Assay Products
No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for TNRC6C Gene
Disorders for TNRC6C Gene
| Disorder | Aliases | PubMed IDs |
|---|---|---|
| epidermodysplasia verruciformis 1 |
|
|
Search TNRC6C in MalaCards
View complete list of genes associated with diseases
Additional Disease Information for TNRC6C
No data available for UniProtKB/Swiss-Prot and Genatlas for TNRC6C Gene
Publications for TNRC6C Gene
- Early origin and adaptive evolution of the GW182 protein family, the key component of RNA silencing in animals. (PMID: 26106978) Zielezinski A … Karlowski WM (RNA biology 2015) 2 3
- GW182 proteins directly recruit cytoplasmic deadenylase complexes to miRNA targets. (PMID: 21981923) Braun JE … Izaurralde E (Molecular cell 2011) 3 4
- miRNA-mediated deadenylation is orchestrated by GW182 through two conserved motifs that interact with CCR4-NOT. (PMID: 21984185) Fabian MR … Sonenberg N (Nature structural & molecular biology 2011) 3 4
- miRNA repression involves GW182-mediated recruitment of CCR4-NOT through conserved W-containing motifs. (PMID: 21984184) Chekulaeva M … Filipowicz W (Nature structural & molecular biology 2011) 3 4
- Mammalian miRNA RISC recruits CAF1 and PABP to affect PABP-dependent deadenylation. (PMID: 19716330) Fabian MR … Sonenberg N (Molecular cell 2009) 3 4
ExternalLinks
Products for TNRC6C Gene
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- Abcam antibodies for TNRC6C
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- Invitrogen Antibodies for TNRC6C (AFLGC-TNRC6C)
- VectorBuilder Custom and pre-made DNA vectors for TNRC6C (ie. gene expression, shRNA knockdown, CRISPR)
- VectorBuilder Viral vectors for TNRC6C (ie. lentivirus, AAV, adenovirus)
- VectorBuilder CRISPR vectors for TNRC6C (ie. knockout, knockin, CRISPRa, CRISPRi)
- VectorBuilder Virus packaging for TNRC6C CRISPR vectors (ie. lentivirus, AAV, adenovirus)
- VectorBuilder Stable cell line generation for TNRC6C
- Addgene plasmids for TNRC6C
- antibodies-online: Show 11 available TNRC6C Antibodies ranked by validation data
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- antibodies-online: Search results for available TNRC6C related products ranked by validation data
- antibodies-online: Search results for available TNRC6C related products ranked by validation data
- Horizon Cell Lines for TNRC6C
- Browse GeneCopoeia Cell Lines
- Search GeneCopoeia for CRISPR/Cas9 clones, lentivirus and AAV products for TNRC6C
- Search GeneCopoeia for ORF cDNA, lentivirus, AAV viral particles and/or promoter clone products for TNRC6C
- Search GeneCopoeia for miRNA 3'UTR Target clone products for TNRC6C
- Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for TNRC6C
- Signalway ELISA kits for TNRC6C
Sources for TNRC6C Gene
- (1) GeneCards
- (2) HGNC
- (3) NCBI Entrez Gene
- (4) UniProtKB/Swiss-Prot
- (5) Ensembl
- (6) OMIM
- (7) GeneLoc
- (8) Gene Wiki
- (9) UCSC
- (10) PhosphoSitePlus
- (11) Cell Signaling Technology
- (12) GO
- (13) UniProtKB/TrEMBL
- (14) InterPro
- (15) ProtoNet
- (16) Blocks
- (17) MGI
- (18) IUBMB
- (19) KEGG
- (20) MINT
- (21) STRING
- (22) IntAct
- (23) Novoseek
- (24) PharmGKB
- (25) DrugBank
- (26) HMDB
- (27) ASD
- (28) SAGE
- (29) SOURCE
- (30) HomoloGene
- (31) PanEnsembl
- (32) euGenes
- (33) SGD
- (34) FlyBase
- (35) WormBase
- (36) Pseudogene
- (37) DGV
- (38) dbSNP
- (39) GenAtlas
- (40) HGMD
- (41) GAD
- (42) BGMUT
- (43) HuGE
- (44) Atlas
- (45) GenBank
- (46) HORDE
- (47) HUGE
- (48) IMGT
- (49) Leiden
- (50) miRBase
- (51) DME
- (52) OriGene
- (53) PubMed
- (54) R&D Systems
- (55) TGDB
- (56) Tocris
- (57) Abcam
- (58) Novus Biologicals
- (59) ProSpec
- (60) Sino Biological
- (61) GenScript
- (62) Qiagen
- (63) OCA
- (64) Proteopedia
- (65) MOPED
- (66) neXtProt
- (67) Reactome
- (68) GeneGo (Thomson Reuters)
- (69) DISEASES
- (70) SIMAP
- (71) GenomeRNAi
- (72) LifeMap
- (73) miRTarBase
- (74) MalaCards
- (75) Invitrogen
- (76) BitterDB
- (77) ESI-BIO
- (78) RefSeq
- (79) BioSystems
- (80) MaxQB
- (81) IUPHAR
- (82) BioGPS
- (83) Illumina
- (84) COMPARTMENTS
- (85) HOMER
- (86) PaxDb
- (87) ApexBio
- (88) Addgene
- (89) antibodies-online
- (90) CYP
- (91) NONCODE
- (92) TreeFam
- (93) PathCards
- (94) GeneReviews
- (95) GeneTex
- (96) Taconic Biosciences
- (97) GTEx
- (98) ProteomicsDB
- (99) SCBT
- (100) DGIdb
- (101) ClinicalTrials
- (102) RVIS
- (103) SIGNOR
- (104) diseasecard
- (105) NIH Rare Diseases
- (106) Orphanet
- (107) UMLS
- (108) GTR
- (109) Disease Ontology
- (110) Genetics Home Reference
- (111) MeSH
- (112) MedlinePlus
- (113) CDC
- (114) NINDS
- (115) NCBI Bookshelf
- (116) ClinVar
- (117) Gene Damage Index
- (118) HPO
- (119) UDN
- (120) VISTA
- (121) FANTOM5
- (122) ENCODE
- (123) ProSci
- (124) Horizon
- (125) The Signaling Pathways Project (SPP)
- (126) IID
- (127) VectorBuilder
- (128) SNPedia
- (129) BRCA Exchange
- (130) CIViC
- (131) ProteoGenix
- (132) dbSUPER
- (133) TISSUES
- (134) Gene ORGANizer
- (135) abm
- (136) Human Protein Atlas
- (137) GWAS Catalog
- (138) Monarch Initiative
- (139) DataMed
- (140) HumanCyc
- (141) UCNEbase
- (142) EPDnew
- (143) Applied Biosystems
- (144) GlyConnect
- (145) Aminode
- (146) GeneCopoeia
- (147) GPS-Prot
- (148) RNACentral
- (149) LncRNADisease
- (150) LOVD
- (151) miR2Disease
- (152) DiseaseEnhancer
- (153) Boster Bio
- (154) Biorbyt
- (155) Biocompare
- (156) Mastermind
- (157) CTD^2 Dashboard
- (158) CraniofacialAtlas
- (159) GeneImprint
- (160) Synthego
- (161) ENA
- (162) GtRNAdb
- (163) LncBase
- (164) LncBook
- (165) LNCipedia
- (166) Modomics
- (167) PDBe
- (168) Rfam
- (169) SILVA
- (170) snOPY
- (171) SRPDB
- (172) GENCODE
- (173) TarBase
- (174) Signalway Antibody
- (175) Open Targets Platform
- (176) 5SRRNADB
- (177) snoDB
- (178) MirGeneDB