The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor is expressed preferentially in the tissues enriched in lymphocytes, and it may play a role in regulating lymphocyte homeostasis. This receptor has been shown to stimulate NF-kappa B activity and regulate cell apoptosis. The signal transduction of this receptor is mediated by various deat... See more...

Aliases for TNFRSF25 Gene

Aliases for TNFRSF25 Gene

  • TNF Receptor Superfamily Member 25 2 3 5
  • Tumor Necrosis Factor Receptor Superfamily, Member 12 (Translocating Chain-Association Membrane Protein) 2 3
  • Tumor Necrosis Factor Receptor Superfamily Member 25 3 4
  • Lymphocyte-Associated Receptor Of Death 3 4
  • Apoptosis-Mediating Receptor TRAMP 3 4
  • Apoptosis-Mediating Receptor DR3 3 4
  • Apoptosis-Inducing Receptor AIR 3 4
  • Protein WSL-1 3 4
  • TNFRSF12 3 4
  • DDR3 3 4
  • LARD 3 4
  • DR3 3 4
  • Pleckstrin Homology Domain-Containing Family G Member 5 3
  • Tumor Necrosis Factor Receptor Superfamily, Member 25 2
  • Guanine Nucleotide Exchange Factor 720 3
  • PH Domain-Containing Family G Member 5 3
  • Death Domain Receptor 3 Soluble Form 3
  • Apoptosis Inducing Receptor 3
  • Death Receptor Beta 3
  • Death Receptor 3 4
  • Protein WSL 4
  • PLEKHG5 3
  • GEF720 3
  • WSL-LR 3
  • APO-3 3
  • TRAMP 3
  • WSL-1 3
  • Apo-3 4
  • APO3 4
  • WSL1 4
  • TR3 3
  • WSL 4

External Ids for TNFRSF25 Gene

Previous HGNC Symbols for TNFRSF25 Gene

  • TNFRSF12

Previous GeneCards Identifiers for TNFRSF25 Gene

  • GC01M006330
  • GC01M006117
  • GC01M006230
  • GC01M006455
  • GC01M006521
  • GC01M005668

Summaries for TNFRSF25 Gene

Entrez Gene Summary for TNFRSF25 Gene

  • The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor is expressed preferentially in the tissues enriched in lymphocytes, and it may play a role in regulating lymphocyte homeostasis. This receptor has been shown to stimulate NF-kappa B activity and regulate cell apoptosis. The signal transduction of this receptor is mediated by various death domain containing adaptor proteins. Knockout studies in mice suggested the role of this gene in the removal of self-reactive T cells in the thymus. Multiple alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported, most of which are potentially secreted molecules. The alternative splicing of this gene in B and T cells encounters a programmed change upon T-cell activation, which predominantly produces full-length, membrane bound isoforms, and is thought to be involved in controlling lymphocyte proliferation induced by T-cell activation. [provided by RefSeq, Jul 2008]

GeneCards Summary for TNFRSF25 Gene

TNFRSF25 (TNF Receptor Superfamily Member 25) is a Protein Coding gene. Diseases associated with TNFRSF25 include Juvenile Dermatitis Herpetiformis and Autoimmune Disease Of Gastrointestinal Tract. Among its related pathways are ERK Signaling and TGF-Beta Pathway. Gene Ontology (GO) annotations related to this gene include tumor necrosis factor-activated receptor activity. An important paralog of this gene is TNFRSF21.

UniProtKB/Swiss-Prot Summary for TNFRSF25 Gene

  • Receptor for TNFSF12/APO3L/TWEAK. Interacts directly with the adapter TRADD. Mediates activation of NF-kappa-B and induces apoptosis. May play a role in regulating lymphocyte homeostasis.

Gene Wiki entry for TNFRSF25 Gene

Additional gene information for TNFRSF25 Gene

No data available for CIViC Summary , Tocris Summary , PharmGKB "VIP" Summary , Rfam classification and piRNA Summary for TNFRSF25 Gene

Genomics for TNFRSF25 Gene

GeneHancer (GH) Regulatory Elements for TNFRSF25 Gene

Promoters and enhancers for TNFRSF25 Gene
GeneHancer (GH) Identifier GH Type GH
Score
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH01J006464 Promoter/Enhancer 1.5 EPDnew Ensembl ENCODE dbSUPER 500.7 +0.8 795 4 POLR2G ZNF10 ZIC2 CTCF ZNF384 POLR2A RAD21 SAP130 E2F6 IKZF1 TNFRSF25 lnc-PLEKHG5-1 ESPN NOL9 ZBTB48 lnc-PLEKHG5-2 PLEKHG5
GH01J006469 Promoter 0.5 EPDnew 500.7 -2.9 -2948 0.1 ZNF263 ZNF513 TNFRSF25 ESPN lnc-ESPN-4 PLEKHG5
GH01J005990 Promoter/Enhancer 2.5 EPDnew FANTOM5 Ensembl ENCODE CraniofacialAtlas dbSUPER 21.2 +473.2 473164 4.9 FOXK2 HNRNPK ZBTB40 ZNF217 EP300 CTCF SIN3A NRF1 POLR2G USF1 NPHP4 KCNAB2 TNFRSF25 ZBTB48 PHF13 THAP3 NOL9 CHD5 piR-61945-001
GH01J006487 Promoter/Enhancer 2.5 EPDnew Ensembl ENCODE CraniofacialAtlas dbSUPER 20.8 -24.4 -24363 6 HNRNPK ZBTB40 CTCF NRF1 POLR2G SP1 NCOR1 BCLAF1 RBAK PHF8 PLEKHG5 TNFRSF25 KLHL21 PHF13 THAP3 ESPN lnc-ESPN-4 RF00017-021
GH01J006497 Promoter/Enhancer 1.9 EPDnew Ensembl ENCODE CraniofacialAtlas dbSUPER 15.8 -31.0 -31006 2.4 ZBTB40 ZIC2 ZBTB10 ZNF423 ZBTB26 RFX1 EZH2 HDAC2 MXI1 ZNF341 PLEKHG5 TNFRSF25 ESPN lnc-ESPN-4 RF00017-021
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data from 2017 publication | Request up-to-date GeneHancer data (full dataset)

GeneHancers around TNFRSF25 on UCSC Golden Path with GeneCards custom track

Cistromic (ChIP-Seq) regulation report from SPP (The Signaling Pathways Project) for TNFRSF25

Top Transcription factor binding sites by QIAGEN in the TNFRSF25 gene promoter:
  • AP-1
  • p53

Genomic Locations for TNFRSF25 Gene

Genomic Locations for TNFRSF25 Gene
chr1:6,460,786-6,466,195
(GRCh38/hg38)
Size:
5,410 bases
Orientation:
Minus strand
chr1:6,521,211-6,526,255
(GRCh37/hg19)
Size:
5,045 bases
Orientation:
Minus strand

Genomic View for TNFRSF25 Gene

Genes around TNFRSF25 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
TNFRSF25 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for TNFRSF25 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for TNFRSF25 Gene

Proteins for TNFRSF25 Gene

  • Protein details for TNFRSF25 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q93038-TNR25_HUMAN
    Recommended name:
    Tumor necrosis factor receptor superfamily member 25
    Protein Accession:
    Q93038
    Secondary Accessions:
    • B1ALX2
    • B1ALX3
    • B7ZLL7
    • O00275
    • O00276
    • O00277
    • O00278
    • O00279
    • O00280
    • O14865
    • O14866
    • P78507
    • P78515
    • Q17RU4
    • Q92983
    • Q93036
    • Q93037
    • Q99722
    • Q99830
    • Q99831
    • Q9BY86
    • Q9UME0
    • Q9UME1
    • Q9UME5

    Protein attributes for TNFRSF25 Gene

    Size:
    417 amino acids
    Molecular mass:
    45385 Da
    Quaternary structure:
    • Homodimer. Interacts strongly via the death domains with TNFRSF1 and TRADD to activate at least two distinct signaling cascades, apoptosis and NF-kappa-B signaling. Interacts with BAG4.
    Miscellaneous:
    • [Isoform 3]: May be produced at very low levels due to a premature stop codon in the mRNA, leading to nonsense-mediated mRNA decay.
    • [Isoform 4]: May be produced at very low levels due to a premature stop codon in the mRNA, leading to nonsense-mediated mRNA decay.
    • [Isoform 5]: May be produced at very low levels due to a premature stop codon in the mRNA, leading to nonsense-mediated mRNA decay.
    • [Isoform 6]: May be produced at very low levels due to a premature stop codon in the mRNA, leading to nonsense-mediated mRNA decay.
    • [Isoform 7]: May be produced at very low levels due to a premature stop codon in the mRNA, leading to nonsense-mediated mRNA decay.
    • [Isoform 12]: May be produced at very low levels due to a premature stop codon in the mRNA, leading to nonsense-mediated mRNA decay.

    Three dimensional structures from OCA and Proteopedia for TNFRSF25 Gene

    Alternative splice isoforms for TNFRSF25 Gene

neXtProt entry for TNFRSF25 Gene

Post-translational modifications for TNFRSF25 Gene

Antibody Products

  • Abcam antibodies for TNFRSF25
  • Boster Bio Antibodies for TNFRSF25

No data available for DME Specific Peptides for TNFRSF25 Gene

Domains & Families for TNFRSF25 Gene

Gene Families for TNFRSF25 Gene

Protein Domains for TNFRSF25 Gene

Blocks:
  • TNFR/CD27/30/40/95 cysteine-rich region
  • Death domain
InterPro:
ProtoNet:

Suggested Antigen Peptide Sequences for TNFRSF25 Gene

GenScript: Design optimal peptide antigens:
  • Tumor necrosis factor receptor superfamily member 25 deletion mutant (A5LIN1_HUMAN)
  • Tumor necrosis factor receptor superfamily, member 25 (B1ALX0_HUMAN)
  • Tumor necrosis factor receptor superfamily, member 25 (B1ALX4_HUMAN)
  • Protein WSL-1 (TNR25_HUMAN)
genes like me logo Genes that share domains with TNFRSF25: view

No data available for Graphical View of Domain Structure and UniProtKB/Swiss-Prot for TNFRSF25 Gene

Function for TNFRSF25 Gene

Molecular function for TNFRSF25 Gene

UniProtKB/Swiss-Prot Function:
Receptor for TNFSF12/APO3L/TWEAK. Interacts directly with the adapter TRADD. Mediates activation of NF-kappa-B and induces apoptosis. May play a role in regulating lymphocyte homeostasis.

Gene Ontology (GO) - Molecular Function for TNFRSF25 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005031 tumor necrosis factor-activated receptor activity TAS 9052839
GO:0005515 protein binding IEA --
GO:0038023 signaling receptor activity NAS 9114039
genes like me logo Genes that share ontologies with TNFRSF25: view
genes like me logo Genes that share phenotypes with TNFRSF25: view

Animal Models for TNFRSF25 Gene

MGI Knock Outs for TNFRSF25:

Animal Model Products

miRNA for TNFRSF25 Gene

miRTarBase miRNAs that target TNFRSF25

Clone Products

No data available for Enzyme Numbers (IUBMB) , Phenotypes From GWAS Catalog , Human Phenotype Ontology , Transcription Factor Targets and HOMER Transcription for TNFRSF25 Gene

Localization for TNFRSF25 Gene

Subcellular locations from UniProtKB/Swiss-Prot for TNFRSF25 Gene

[Isoform 1]: Cell membrane; Single-pass type I membrane protein.
[Isoform 2]: Cell membrane; Single-pass type I membrane protein.
[Isoform 9]: Cell membrane; Single-pass type I membrane protein.
[Isoform 11]: Cell membrane; Single-pass type I membrane protein.
[Isoform 3]: Secreted.
[Isoform 4]: Secreted.
[Isoform 5]: Secreted.
[Isoform 6]: Secreted.
[Isoform 7]: Secreted.
[Isoform 8]: Secreted.
[Isoform 10]: Secreted.
[Isoform 12]: Secreted.

Subcellular locations from

COMPARTMENTS
Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for TNFRSF25 gene
Compartment Confidence
plasma membrane 5
extracellular 5
cytosol 5
nucleus 3
cytoskeleton 2
mitochondrion 2
endoplasmic reticulum 2
endosome 2
lysosome 2
peroxisome 1
golgi apparatus 1

Subcellular locations from the

Human Protein Atlas (HPA)
  • Actin filaments (2)
  • Focal adhesion sites (2)
  • Nucleoplasm (2)
  • Plasma membrane (2)
See all subcellular structures

Gene Ontology (GO) - Cellular Components for TNFRSF25 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005576 extracellular region IEA --
GO:0005829 cytosol NAS 9114039
GO:0005886 plasma membrane TAS,IDA --
GO:0005887 integral component of plasma membrane TAS 9052839
GO:0016020 membrane IEA --
genes like me logo Genes that share ontologies with TNFRSF25: view

Pathways & Interactions for TNFRSF25 Gene

PathCards logo

SuperPathways for TNFRSF25 Gene

SuperPathway Contained pathways
1 Apoptosis Modulation and Signaling
.41
.35
2 PEDF Induced Signaling
.51
.47
.43
3 Akt Signaling
.60
.60
.55
4 TNFR1 Pathway
.87
.87
.42
5 TGF-Beta Pathway
.60
.57
.51
genes like me logo Genes that share pathways with TNFRSF25: view

Pathways by source for TNFRSF25 Gene

1 Sino Biological pathway for TNFRSF25 Gene
2 BioSystems pathways for TNFRSF25 Gene
1 KEGG pathway for TNFRSF25 Gene
2 GeneGo (Thomson Reuters) pathways for TNFRSF25 Gene
  • Apoptosis and survival Anti-apoptotic TNFs/NF-kB/IAP pathway
  • Apoptosis and survival Apoptotic TNF-family pathways
15 Qiagen pathways for TNFRSF25 Gene
  • Akt Signaling
  • Antioxidant Action of Vitamin-C
  • Apoptosis through Death Receptors
  • DR3 Signaling
  • Glucocorticoid Receptor Signaling
2 Cell Signaling Technology pathways for TNFRSF25 Gene

SIGNOR curated interactions for TNFRSF25 Gene

Activates:
Is activated by:

Gene Ontology (GO) - Biological Process for TNFRSF25 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0006915 apoptotic process TAS,NAS 9114039
GO:0007165 signal transduction TAS 8875942
GO:0007166 cell surface receptor signaling pathway TAS 9052839
GO:0033209 tumor necrosis factor-mediated signaling pathway TAS --
GO:0042981 regulation of apoptotic process NAS 9114039
genes like me logo Genes that share ontologies with TNFRSF25: view

Drugs & Compounds for TNFRSF25 Gene

(1) Drugs for TNFRSF25 Gene - From: DGIdb and IUPHAR

Name Status Disease Links Group Role Mechanism of Action Clinical Trials
TL1A Pharma 0
genes like me logo Genes that share compounds with TNFRSF25: view

Transcripts for TNFRSF25 Gene

mRNA/cDNA for TNFRSF25 Gene

9 REFSEQ mRNAs :
27 NCBI additional mRNA sequence :
21 Ensembl transcripts including schematic representations, and UCSC links to gene/alias where relevant :

Clone Products

Alternative Splicing Database (ASD) splice patterns (SP) for TNFRSF25 Gene

No ASD Table

Relevant External Links for TNFRSF25 Gene

GeneLoc Exon Structure for
TNFRSF25

Expression for TNFRSF25 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and SAGE for TNFRSF25 Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

mRNA differential expression in normal tissues according to GTEx for TNFRSF25 Gene

This gene is overexpressed in Brain - Cerebellum (x9.3) and Brain - Cerebellar Hemisphere (x8.5).

Protein differential expression in normal tissues from HIPED for TNFRSF25 Gene

This gene is overexpressed in Adipocyte (69.0).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB and MOPED for TNFRSF25 Gene



Protein tissue co-expression partners for TNFRSF25 Gene

Transcriptomic regulation report from SPP (The Signaling Pathways Project) for TNFRSF25

SOURCE GeneReport for Unigene cluster for TNFRSF25 Gene:

Hs.462529

mRNA Expression by UniProt/SwissProt for TNFRSF25 Gene:

Q93038-TNR25_HUMAN
Tissue specificity: Abundantly expressed in thymocytes and lymphocytes. Detected in lymphocyte-rich tissues such as thymus, colon, intestine, and spleen. Also found in the prostate.

Evidence on tissue expression from TISSUES for TNFRSF25 Gene

  • Nervous system(4.5)
  • Heart(4.3)
  • Lung(4.3)
  • Blood(2.8)
  • Skin(2.8)
  • Thyroid gland(2.5)
  • Intestine(2.4)
  • Spleen(2.4)
  • Lymph node(2.2)
  • Pancreas(2.1)
genes like me logo Genes that share expression patterns with TNFRSF25: view

No data available for Phenotype-based relationships between genes and organs from Gene ORGANizer for TNFRSF25 Gene

Orthologs for TNFRSF25 Gene

This gene was present in the common ancestor of chordates.

Orthologs for TNFRSF25 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia TNFRSF25 31 30
  • 96.25 (n)
OneToOne
dog
(Canis familiaris)
Mammalia TNFRSF25 31 30
  • 80.53 (n)
OneToOne
cow
(Bos Taurus)
Mammalia TNFRSF25 31 30
  • 78.35 (n)
OneToOne
mouse
(Mus musculus)
Mammalia Tnfrsf25 17 31 30
  • 75.7 (n)
rat
(Rattus norvegicus)
Mammalia Tnfrsf25 30
  • 73.67 (n)
oppossum
(Monodelphis domestica)
Mammalia TNFRSF25 31
  • 50 (a)
OneToOne
platypus
(Ornithorhynchus anatinus)
Mammalia TNFRSF25 31
  • 46 (a)
OneToOne
chicken
(Gallus gallus)
Aves TNFRSF25 31 30
  • 54.17 (n)
OneToOne
zebrafish
(Danio rerio)
Actinopterygii TNFRSF25 31
  • 22 (a)
OneToOne
Species where no ortholog for TNFRSF25 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for TNFRSF25 Gene

ENSEMBL:
Gene Tree for TNFRSF25 (if available)
TreeFam:
Gene Tree for TNFRSF25 (if available)
Aminode:
Evolutionary constrained regions (ECRs) for TNFRSF25: view image

Paralogs for TNFRSF25 Gene

Variants for TNFRSF25 Gene

Sequence variations, with clinical significance, from ClinVar and Humsavar, with links to dbSNP for TNFRSF25 Gene

SNP ID Clinical significance and condition Chr 01 pos Variation AA Info Type
719229 Benign: not provided 6,462,148(-) G/A SYNONYMOUS_VARIANT
777869 Benign: not provided 6,464,589(-) T/C SYNONYMOUS_VARIANT,INTRON_VARIANT
789686 Likely Benign: not provided 6,462,184(-) A/G INTRON_VARIANT
rs3007417 Benign: Distal spinal muscular atrophy 6,466,123(-) G/A FIVE_PRIME_UTR_VARIANT,THREE_PRIME_UTR_VARIANT
rs45542640 Benign: Distal spinal muscular atrophy 6,466,180(-) GCGCC/G FIVE_PRIME_UTR_VARIANT,THREE_PRIME_UTR_VARIANT

Additional dbSNP identifiers (rs#s) for TNFRSF25 Gene

Structural Variations from Database of Genomic Variants (DGV) for TNFRSF25 Gene

Variant ID Type Subtype PubMed ID
dgv2n27 CNV loss 19166990
dgv80n54 CNV loss 21841781
dgv9n67 CNV gain 20364138
esv25412 CNV gain+loss 19812545
nsv1009548 CNV loss 25217958
nsv462061 CNV loss 19166990
nsv470690 CNV gain 18288195
nsv470691 CNV loss 18288195
nsv508836 CNV insertion 20534489
nsv545240 CNV loss 21841781
nsv545264 CNV loss 21841781
nsv545265 CNV loss 21841781
nsv545266 CNV loss 21841781
nsv7880 CNV gain+loss 18304495
nsv831536 CNV loss 17160897
nsv954048 CNV deletion 24416366

Variation tolerance for TNFRSF25 Gene

Residual Variation Intolerance Score: 46.8% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 4.56; 65.00% of all genes are more intolerant (likely to be disease-causing)

Additional Variant Information for TNFRSF25 Gene

Human Gene Mutation Database (HGMD)
TNFRSF25
SNPedia medical, phenotypic, and genealogical associations of SNPs for
TNFRSF25

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for TNFRSF25 Gene

Disorders for TNFRSF25 Gene

MalaCards: The human disease database

(34) MalaCards diseases for TNFRSF25 Gene - From: DISEASES and GeneCards

- elite association - COSMIC cancer census association via MalaCards

Additional Disease Information for TNFRSF25

Genetic Association Database
(GAD)
Human Genome Epidemiology Navigator
(HuGE)
ATLAS of Genetics and Cytogenetics in Oncology and Haematology
genes like me logo Genes that share disorders with TNFRSF25: view

No data available for UniProtKB/Swiss-Prot and Genatlas for TNFRSF25 Gene

Publications for TNFRSF25 Gene

  1. TRAMP, a novel apoptosis-mediating receptor with sequence homology to tumor necrosis factor receptor 1 and Fas(Apo-1/CD95). (PMID: 9052839) Bodmer JL … Tschopp J (Immunity 1997) 2 3 4 54
  2. Signal transduction by DR3, a death domain-containing receptor related to TNFR-1 and CD95. (PMID: 8875942) Chinnaiyan AM … Dixit VM (Science (New York, N.Y.) 1996) 3 4 23 54
  3. A death-domain-containing receptor that mediates apoptosis. (PMID: 8934525) Kitson J … Farrow SN (Nature 1996) 2 3 4 54
  4. Common single nucleotide polymorphisms in immunoregulatory genes and multiple myeloma risk among women in Connecticut. (PMID: 20568250) Lee KM … Lan Q (American journal of hematology 2010) 3 41 54
  5. Immunology: TL1A in the inflammatory network in autoimmune diseases. (PMID: 20125169) Bayry J (Nature reviews. Rheumatology 2010) 3 23 54

Products for TNFRSF25 Gene

  • Boster Bio Antibodies for TNFRSF25
  • Boster Bio ELISA Kits for TNFRSF25

Sources for TNFRSF25 Gene