TNFRSF13B Gene (Protein Coding)

TNF Receptor Superfamily Member 13B

GC17M016929
GIFtS:
47
The protein encoded by this gene is a lymphocyte-specific member of the tumor necrosis factor (TNF) receptor superfamily. It interacts with calcium-modulator and cyclophilin ligand (CAML). The protein induces activation of the transcription factors NFAT, AP1, and NF-kappa-B and plays a crucial role in humoral immunity by interacting with a TNF ligand. This gene is located withi... See more...

Aliases for TNFRSF13B Gene

Aliases for TNFRSF13B Gene

  • TNF Receptor Superfamily Member 13B 2 3 5
  • TACI 2 3 4
  • Tumor Necrosis Factor Receptor Superfamily Member 13B 3 4
  • Transmembrane Activator And CAML Interactor 3 4
  • CD267 2 3
  • IGAD2 2 3
  • Tumor Necrosis Factor Receptor Superfamily, Member 13B 2
  • Tumor Necrosis Factor Receptor 13B 3
  • CD267 Antigen 4
  • TNFRSF14B 3
  • TNFRSF13B 5
  • CVID2 3
  • CVID 3
  • RYZN 3

External Ids for TNFRSF13B Gene

Previous GeneCards Identifiers for TNFRSF13B Gene

  • GC17M017204
  • GC17M017953
  • GC17M016785
  • GC17M017042
  • GC17M016783
  • GC17M016595
  • GC17M016832

Summaries for TNFRSF13B Gene

Entrez Gene Summary for TNFRSF13B Gene

  • The protein encoded by this gene is a lymphocyte-specific member of the tumor necrosis factor (TNF) receptor superfamily. It interacts with calcium-modulator and cyclophilin ligand (CAML). The protein induces activation of the transcription factors NFAT, AP1, and NF-kappa-B and plays a crucial role in humoral immunity by interacting with a TNF ligand. This gene is located within the Smith-Magenis syndrome region on chromosome 17. [provided by RefSeq, Jul 2008]

GeneCards Summary for TNFRSF13B Gene

TNFRSF13B (TNF Receptor Superfamily Member 13B) is a Protein Coding gene. Diseases associated with TNFRSF13B include Immunodeficiency, Common Variable, 2 and Immunoglobulin A Deficiency 2. Among its related pathways are RANK Signaling in Osteoclasts and Innate Immune System.

UniProtKB/Swiss-Prot Summary for TNFRSF13B Gene

  • Receptor for TNFSF13/APRIL and TNFSF13B/TALL1/BAFF/BLYS that binds both ligands with similar high affinity. Mediates calcineurin-dependent activation of NF-AT, as well as activation of NF-kappa-B and AP-1. Involved in the stimulation of B- and T-cell function and the regulation of humoral immunity.

Gene Wiki entry for TNFRSF13B Gene

Additional gene information for TNFRSF13B Gene

No data available for CIViC Summary , Tocris Summary , PharmGKB "VIP" Summary , Rfam classification and piRNA Summary for TNFRSF13B Gene

Genomics for TNFRSF13B Gene

GeneHancer (GH) Regulatory Elements Pubs

Download GeneHancer 2017 data
Promoters and enhancers for TNFRSF13B Gene
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data from 2017 publication | Request up-to-date GeneHancer data (full dataset)

GeneHancers around TNFRSF13B on the GeneHancer Hub at the UCSC Golden Path

Cistromic (ChIP-Seq) regulation report from SPP (The Signaling Pathways Project) for TNFRSF13B

Top Transcription factor binding sites by QIAGEN in the TNFRSF13B gene promoter:
  • AP-1
  • ATF-2
  • c-Jun
  • FOXD1
  • POU2F1
  • POU2F1a

Genomic Locations for TNFRSF13B Gene

Latest Assembly
chr17:16,929,816-16,972,118
(GRCh38/hg38)
Size:
42,303 bases
Orientation:
Minus strand

Previous Assembly
chr17:16,842,395-16,875,432
(GRCh37/hg19 by Entrez Gene)
Size:
33,038 bases
Orientation:
Minus strand

chr17:16,832,849-16,875,432
(GRCh37/hg19 by Ensembl)
Size:
42,584 bases
Orientation:
Minus strand

Genomic View for TNFRSF13B Gene

Genes around TNFRSF13B on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
TNFRSF13B Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for TNFRSF13B Gene
GeneLoc Logo Genomic Neighborhood • Exon Structure • Gene Density

RefSeq DNA sequence for TNFRSF13B Gene

Proteins for TNFRSF13B Gene

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  • Protein details for TNFRSF13B Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    O14836-TR13B_HUMAN
    Recommended name:
    Tumor necrosis factor receptor superfamily member 13B
    Protein Accession:
    O14836
    Secondary Accessions:
    • B2R8B0
    • B7Z6V8
    • Q32LX4
    • Q7Z6F5

    Protein attributes for TNFRSF13B Gene

    Size:
    293 amino acids
    Molecular mass:
    31816 Da
    Quaternary structure:
    • Binds TRAF2, TRAF5 and TRAF6. Binds the NH2-terminal domain of CAMLG with its C-terminus.

    Three dimensional structures from OCA and Proteopedia for TNFRSF13B Gene

    Alternative splice isoforms for TNFRSF13B Gene

    UniProtKB/Swiss-Prot:

neXtProt entry for TNFRSF13B Gene

Protein Expression for TNFRSF13B Gene

See protein expression from ProteomicsDB, MOPED, PaxDb, and MaxQB

Post-translational modifications for TNFRSF13B Gene

  • Glycosylation at Asn128
  • Modification sites at PhosphoSitePlus

Other Protein References for TNFRSF13B Gene

ENSEMBL proteins:
REFSEQ proteins:

Antibodies for research

  • Abcam antibodies for TNFRSF13B

No data available for DME Specific Peptides for TNFRSF13B Gene

Domains & Families for TNFRSF13B Gene

Gene Families for TNFRSF13B Gene

HGNC:
IUPHAR :
Human Protein Atlas (HPA):
  • CD markers
  • Disease related genes
  • Predicted intracellular proteins
  • Predicted membrane proteins

Protein Domains for TNFRSF13B Gene

InterPro:
Blocks:
  • TNFR/CD27/30/40/95 cysteine-rich region
ProtoNet:

Suggested Antigen Peptide Sequences for TNFRSF13B Gene

GenScript: Design optimal peptide antigens:
  • Tumor necrosis factor receptor superfamily, member 13B, isoform CRA_a (Q4ACX1_HUMAN)
  • Transmembrane activator and CAML interactor (TR13B_HUMAN)
genes like me logo Genes that share domains with TNFRSF13B: view

No data available for Graphical View of Domain Structure and UniProtKB/Swiss-Prot for TNFRSF13B Gene

Function for TNFRSF13B Gene

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  6. Cell Lines for research

Molecular function for TNFRSF13B Gene

UniProtKB/Swiss-Prot Function:
Receptor for TNFSF13/APRIL and TNFSF13B/TALL1/BAFF/BLYS that binds both ligands with similar high affinity. Mediates calcineurin-dependent activation of NF-AT, as well as activation of NF-kappa-B and AP-1. Involved in the stimulation of B- and T-cell function and the regulation of humoral immunity.

Phenotypes From GWAS Catalog for TNFRSF13B Gene

Gene Ontology (GO) - Molecular Function for TNFRSF13B Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005515 protein binding IPI 10801128
GO:0038023 signaling receptor activity TAS 9311921
genes like me logo Genes that share ontologies with TNFRSF13B: view
genes like me logo Genes that share phenotypes with TNFRSF13B: view

Human Phenotype Ontology for TNFRSF13B Gene

HPO Id HPO Name Alternative Ids Definition Synonyms

Animal Models for TNFRSF13B Gene

MGI Knock Outs for TNFRSF13B:

Inhibitory RNAs for research

  • Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for TNFRSF13B

No data available for Enzyme Numbers (IUBMB) , Transcription Factor Targets and HOMER Transcription for TNFRSF13B Gene

Localization for TNFRSF13B Gene

Subcellular locations from UniProtKB/Swiss-Prot for TNFRSF13B Gene

Membrane. Single-pass type III membrane protein.

Subcellular locations from

COMPARTMENTS
Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for TNFRSF13B gene
Compartment Confidence
plasma membrane 5
extracellular 2
mitochondrion 2
nucleus 2
cytosol 2
cytoskeleton 1
endoplasmic reticulum 1
endosome 1
lysosome 1
golgi apparatus 1

Gene Ontology (GO) - Cellular Components for TNFRSF13B Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005886 plasma membrane TAS --
GO:0005887 integral component of plasma membrane TAS,IEA --
GO:0016020 membrane IEA --
GO:0016021 integral component of membrane IEA --
genes like me logo Genes that share ontologies with TNFRSF13B: view

No data available for Subcellular locations from the Human Protein Atlas (HPA) for TNFRSF13B Gene

Pathways & Interactions for TNFRSF13B Gene

PathCards logo

SuperPathways for TNFRSF13B Gene

SuperPathway Contained pathways
1 Akt Signaling
Akt Signaling
.60
p38 Signaling
.60
Tec Kinases Signaling
.55
2 RANK Signaling in Osteoclasts
APRIL Pathway
.92
BAFF in B-Cell Signaling
.92
Apoptosis and survival APRIL and BAFF signaling
.39
3 PEDF Induced Signaling
STAT3 Pathway
.47
Cytokine-cytokine receptor interaction
.43
4 TNF Superfamily Pathway: Human Ligand-Receptor Interactions and their Associated Functions
TNF Superfamily Pathway: Human Ligand-Receptor Interactions and their Associated Functions
.52
TNFs bind their physiological receptors
.52
5 TRAF Pathway
TNF Superfamily Pathway
.42
TRAF Pathway
.42
genes like me logo Genes that share pathways with TNFRSF13B: view

Pathways by source for TNFRSF13B Gene

3 GeneGo (Thomson Reuters) pathways for TNFRSF13B Gene
  • Apoptosis and survival Anti-apoptotic TNFs/NF-kB/Bcl-2 pathway
  • Apoptosis and survival Anti-apoptotic TNFs/NF-kB/IAP pathway
  • Apoptosis and survival APRIL and BAFF signaling
10 Qiagen pathways for TNFRSF13B Gene
  • Akt Signaling
  • Antioxidant Action of Vitamin-C
  • APRIL Pathway
  • BAFF in B-Cell Signaling
  • Molecular Mechanisms of Cancer

SIGNOR curated interactions for TNFRSF13B Gene

Is activated by:

Gene Ontology (GO) - Biological Process for TNFRSF13B Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0001782 B cell homeostasis IBA 21873635
GO:0002244 hematopoietic progenitor cell differentiation IBA 21873635
GO:0002250 adaptive immune response IEA --
GO:0002376 immune system process IEA --
GO:0007166 cell surface receptor signaling pathway TAS 9311921
genes like me logo Genes that share ontologies with TNFRSF13B: view

Drugs & Compounds for TNFRSF13B Gene

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(3) Drugs for TNFRSF13B Gene - From: DGIdb, IUPHAR, and Novoseek

Name Status Disease Links Group Role Mechanism of Action Clinical Trials
BAFF Pharma 0
LYMPHORAD Pharma 0

(2) Additional Compounds for TNFRSF13B Gene - From: Novoseek

Name Synonyms Role CAS Number PubChem IDs PubMed IDs
genes like me logo Genes that share compounds with TNFRSF13B: view

Transcripts for TNFRSF13B Gene

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mRNA/cDNA for TNFRSF13B Gene

1 REFSEQ mRNAs :
9 NCBI additional mRNA sequence :
7 Ensembl transcripts including schematic representations, and UCSC links to gene/alias where relevant :

Inhibitory RNAs for research

  • Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for TNFRSF13B

Alternative Splicing Database (ASD) splice patterns (SP) for TNFRSF13B Gene

No ASD Table

Relevant External Links for TNFRSF13B Gene

GeneLoc Exon Structure for
TNFRSF13B

Expression for TNFRSF13B Gene

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  1. Primer products for research
  2. Gene Expression Assays for research

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and SAGE for TNFRSF13B Gene

mRNA expression in normal human tissues for TNFRSF13B Gene
mRNA expression by GTEx for TNFRSF13B GenemRNA expression by BioGPS for TNFRSF13B Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

mRNA differential expression in normal tissues according to GTEx for TNFRSF13B Gene

This gene is overexpressed in Spleen (x6.3).

Protein differential expression in normal tissues from HIPED for TNFRSF13B Gene

This gene is overexpressed in Peripheral blood mononuclear cells (47.6) and Heart (21.1).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB and MOPED for TNFRSF13B Gene



Protein tissue co-expression partners for TNFRSF13B Gene

- Elite partner

Transcriptomic regulation report from SPP (The Signaling Pathways Project) for TNFRSF13B

SOURCE GeneReport for Unigene cluster for TNFRSF13B Gene:

Hs.158341

mRNA Expression by UniProt/SwissProt for TNFRSF13B Gene:

O14836-TR13B_HUMAN
Tissue specificity: Highly expressed in spleen, thymus, small intestine and peripheral blood leukocytes. Expressed in resting B-cells and activated T-cells, but not in resting T-cells.

Evidence on tissue expression from TISSUES for TNFRSF13B Gene

  • Spleen(4.7)
  • Lymph node(2.9)
  • Bone marrow(2.7)
  • Blood(2.7)
  • Intestine(2.4)
  • Kidney(2.4)
  • Liver(2.2)
  • Lung(2.1)

Phenotype-based relationships between genes and organs from Gene ORGANizer for TNFRSF13B Gene

Germ Layers:
  • ectoderm
  • endoderm
  • mesoderm
Systems:
  • cardiovascular
  • digestive
  • endocrine
  • immune
  • integumentary
  • lymphatic
  • nervous
  • reproductive
  • respiratory
  • skeletal muscle
  • skeleton
Regions:
Head and neck:
  • brain
  • ear
  • eye
  • head
  • hypothalamus
  • meninges
  • middle ear
  • neck
  • pituitary gland
  • sinus
  • skull
  • thyroid
Thorax:
  • bronchus
  • heart
  • lung
Abdomen:
  • adrenal gland
  • intestine
  • large intestine
  • liver
  • small intestine
  • spleen
  • stomach
Pelvis:
  • anus
  • rectum
  • uterus
Limb:
  • ankle
  • digit
  • elbow
  • finger
  • foot
  • hand
  • hip
  • knee
  • lower limb
  • shoulder
  • toe
  • upper limb
  • wrist
General:
  • blood
  • blood vessel
  • bone marrow
  • coagulation system
  • lymph node
  • peripheral nerve
  • peripheral nervous system
  • red blood cell
  • skin
  • white blood cell
genes like me logo Genes that share expression patterns with TNFRSF13B: view

Primer products for research

Orthologs for TNFRSF13B Gene

This gene was present in the common ancestor of chordates.

Orthologs for TNFRSF13B Gene

Organism Taxonomy Gene Similarity Type Details
Chimpanzee
(Pan troglodytes)
 Mammalia TNFRSF13B 30 31
  • 99.54 (n)
 OneToOne
Dog
(Canis familiaris)
 Mammalia TNFRSF13B 30 31
  • 77.25 (n)
 OneToOne
Mouse
(Mus musculus)
 Mammalia Tnfrsf13b 30 17 31
  • 68.64 (n)
 OneToOne
Cow
(Bos Taurus)
 Mammalia TNFRSF13B 31
  • 56 (a)
 OneToOne
Platypus
(Ornithorhynchus anatinus)
 Mammalia TNFRSF13B 31
  • 46 (a)
 OneToOne
Oppossum
(Monodelphis domestica)
 Mammalia TNFRSF13B 31
  • 42 (a)
 OneToOne
Chicken
(Gallus gallus)
 Aves TNFRSF13B 30 31
  • 56.09 (n)
 OneToOne
Lizard
(Anolis carolinensis)
 Reptilia TNFRSF13B 31
  • 38 (a)
 OneToOne
Species where no ortholog for TNFRSF13B was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Eremothecium gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • Alpha proteobacteria (Wolbachia pipientis)
  • Amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • Baker's yeast (Saccharomyces cerevisiae)
  • Barley (Hordeum vulgare)
  • Beta proteobacteria (Neisseria meningitidis)
  • Bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • Common water flea (Daphnia pulex)
  • Corn (Zea mays)
  • E. coli (Escherichia coli)
  • Filamentous fungi (Aspergillus nidulans)
  • Firmicute Bacteria (Streptococcus pneumoniae)
  • Fission Yeast (Schizosaccharomyces pombe)
  • Fruit Fly (Drosophila melanogaster)
  • Green Algae (Chlamydomonas reinhardtii)
  • Honey Bee (Apis mellifera)
  • K. Lactis Yeast (Kluyveromyces lactis)
  • Loblloly Pine (Pinus taeda)
  • Malaria Parasite (Plasmodium falciparum)
  • Medicago Trunc (Medicago Truncatula)
  • Moss (Physcomitrella patens)
  • Orangutan (Pongo pygmaeus)
  • Pig (Sus scrofa)
  • Rainbow Trout (Oncorhynchus mykiss)
  • Rat (Rattus norvegicus)
  • Rice (Oryza sativa)
  • Rice Blast Fungus (Magnaporthe grisea)
  • Schistosome Parasite (Schistosoma mansoni)
  • Sea Anemone (Nematostella vectensis)
  • Sea Vase (Ciona intestinalis)
  • Sea Squirt (Ciona savignyi)
  • Sea Urchin (Strongylocentrotus purpuratus)
  • Sorghum (Sorghum bicolor)
  • Soybean (Glycine max)
  • Stem Rust Fungus (Puccinia graminis)
  • Sugarcane (Saccharum officinarum)
  • Thale Cress (Arabidopsis thaliana)
  • Tomato (Lycopersicon esculentum)
  • Toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • Tropical Clawed Frog (Silurana tropicalis)
  • Wheat (Triticum aestivum)
  • Worm (Caenorhabditis elegans)
  • Zebrafish (Danio rerio)

Evolution for TNFRSF13B Gene

ENSEMBL:
Gene Tree for TNFRSF13B (if available)
TreeFam:
Gene Tree for TNFRSF13B (if available)
Aminode:
Evolutionary constrained regions (ECRs) for TNFRSF13B: view image

Paralogs for TNFRSF13B Gene

(1) SIMAP similar genes for TNFRSF13B Gene using alignment to 3 proteins:

  • TR13B_HUMAN
  • E7ER05_HUMAN
  • J3QR67_HUMAN

Pseudogenes.org Pseudogenes for TNFRSF13B Gene

genes like me logo Genes that share paralogs with TNFRSF13B: view

No data available for Paralogs for TNFRSF13B Gene

Variants for TNFRSF13B Gene

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  1. SNP Genotyping and Copy Number Assays for research

Sequence variations, with clinical significance, from ClinVar and Humsavar, with links to dbSNP for TNFRSF13B Gene

SNP ID Clinical significance and condition Chr 17 pos Variation AA Info Type
834559 Uncertain Significance: Common variable immunodeficiency 2 16,948,765(-) C/T
NM_012452.3(TNFRSF13B):c.418G>A (p.Glu140Lys) 		MISSENSE
835226 Uncertain Significance: Common variable immunodeficiency 2 16,948,818(-) C/T
NM_012452.3(TNFRSF13B):c.365G>A (p.Arg122Gln) 		MISSENSE
840913 Uncertain Significance: Common variable immunodeficiency 2 16,948,969(-) G/A
NM_012452.3(TNFRSF13B):c.214C>T (p.Arg72Cys) 		MISSENSE
840923 Pathogenic: Common variable immunodeficiency 2; Immunoglobulin A deficiency 2 16,952,447(-) G/T
NM_012452.3(TNFRSF13B):c.198C>A (p.Cys66Ter) 		NONSENSE
849649 Uncertain Significance: Common variable immunodeficiency 2 16,952,474(-) C/G
NM_012452.3(TNFRSF13B):c.171G>C (p.Gln57His) 		MISSENSE

dbSNP identifiers (rs#s) for variants without ClinVar clinical significance for TNFRSF13B Gene

All consequence types are included: molecular consequences (e.g. missense, synonymous), and location-based (e.g. intron, upstream).

Structural Variations from Database of Genomic Variants (DGV) for TNFRSF13B Gene

Variant ID Type Subtype PubMed ID
esv2662060 CNV deletion 23128226
esv2666300 CNV deletion 23128226
esv275147 CNV gain+loss 21479260
esv2761948 CNV loss 21179565
esv3640119 CNV loss 21293372
esv3640120 CNV loss 21293372
nsv1055688 CNV gain 25217958
nsv155 OTHER inversion 15895083
nsv499114 OTHER inversion 21111241
nsv524738 CNV loss 19592680
nsv833379 CNV gain 17160897

Variation tolerance for TNFRSF13B Gene

Residual Variation Intolerance Score: 92% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 5.15; 69.42% of all genes are more intolerant (likely to be disease-causing)

Additional Variant Information for TNFRSF13B Gene

Human Gene Mutation Database (HGMD)
TNFRSF13B
SNPedia medical, phenotypic, and genealogical associations of SNPs for
TNFRSF13B

SNP Genotyping and Copy Number Assays for research

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for TNFRSF13B Gene

Disorders for TNFRSF13B Gene

MalaCards: The human disease database

(38) MalaCards diseases for TNFRSF13B Gene - From: OMI, CVR, GTR, ORP, SWI, COP, and GCD

- elite association - COSMIC cancer census association via MalaCards

UniProtKB/Swiss-Prot

TR13B_HUMAN
  • Immunodeficiency, common variable, 2 (CVID2) [MIM:240500]: A primary immunodeficiency characterized by antibody deficiency, hypogammaglobulinemia, recurrent bacterial infections and an inability to mount an antibody response to antigen. The defect results from a failure of B-cell differentiation and impaired secretion of immunoglobulins; the numbers of circulating B-cells is usually in the normal range, but can be low. {ECO:0000269 PubMed:16007086}. Note=The disease is caused by variants affecting the gene represented in this entry.
  • Immunoglobulin A deficiency 2 (IGAD2) [MIM:609529]: Selective deficiency of immunoglobulin A (IGAD) is the most common form of primary immunodeficiency, with an incidence of approximately 1 in 600 individuals in the western world. Individuals with symptomatic IGAD often have deficiency of IgG subclasses or decreased antibody response to carbohydrate antigens such as pneumococcal polysaccharide vaccine. Individuals with IGAD also suffer from recurrent sinopulmonary and gastrointestinal infections and have an increased incidence of autoimmune disorders and of lymphoid and non-lymphoid malignancies. In vitro studies have suggested that some individuals with IGAD have impaired isotype class switching to IgA and others may have a post-switch defect. IGAD and CVID have been known to coexist in families. Some individuals initially present with IGAD1 and then develop CVID. These observations suggest that some cases of IGAD and CVID may have a common etiology. {ECO:0000269 PubMed:16007086}. Note=The disease is caused by variants affecting the gene represented in this entry.

Additional Disease Information for TNFRSF13B

Genetic Association Database
(GAD)
Human Genome Epidemiology Navigator
(HuGE)
Atlas
ATLAS of Genetics and Cytogenetics in Oncology and Haematology
Open Targets Platform
Open Targets Platform
genes like me logo Genes that share disorders with TNFRSF13B: view

No data available for Genatlas for TNFRSF13B Gene

Publications for TNFRSF13B Gene

  1. TACI is mutant in common variable immunodeficiency and IgA deficiency. (PMID: 16007086) Castigli E … Geha RS (Nature genetics 2005) 3 4 23 74
  2. Lymphocyte characteristics in children with common variable immunodeficiency. (PMID: 20006554) van de Ven AA … van Montfrans JM (Clinical immunology (Orlando, Fla.) 2010) 3 23 41
  3. Phenotypic and clinical heterogeneity associated with monoallelic TNFRSF13B-A181E mutations in common variable immunodeficiency. (PMID: 20156508) Dong X … Abraham RS (Human immunology 2010) 3 23 41
  4. An evolutionary approach to the medical implications of the tumor necrosis factor receptor superfamily member 13B (TNFRSF13B) gene. (PMID: 19494827) Sazzini M … Luiselli D (Genes and immunity 2009) 3 23 41
  5. Novel mutations in TACI (TNFRSF13B) causing common variable immunodeficiency. (PMID: 19629655) Mohammadi J … Hammarström L (Journal of clinical immunology 2009) 3 23 41

ExternalLinks

View latest publications for TNFRSF13B gene in Mastermind

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