Aliases for TNFAIP8L2 Gene
External Ids for TNFAIP8L2 Gene
Previous GeneCards Identifiers for TNFAIP8L2 Gene
GeneCards Summary for TNFAIP8L2 Gene
TNFAIP8L2 (TNF Alpha Induced Protein 8 Like 2) is a Protein Coding gene. Diseases associated with TNFAIP8L2 include Skin Squamous Cell Carcinoma. Among its related pathways are PI Metabolism and Metabolism. An important paralog of this gene is TNFAIP8L1.
UniProtKB/Swiss-Prot Summary for TNFAIP8L2 Gene
Acts as a negative regulator of innate and adaptive immunity by maintaining immune homeostasis. Negative regulator of Toll-like receptor and T-cell receptor function. Prevents hyperresponsiveness of the immune system and maintains immune homeostasis. Inhibits JUN/AP1 and NF-kappa-B activation. Promotes Fas-induced apoptosis (By similarity).