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This gene was identified as a gene whose expression can be induced by the tumor necrosis factor alpha (TNF) in umbilical vein endothelial cells. The expression of this gene was shown to be induced by retinoic acid in a cell line expressing a oncogenic version of the retinoic acid receptor alpha fusion protein, which suggested that this gene may be a retinoic acid target gene in... See more...
Aliases for TNFAIP2 Gene
Aliases for TNFAIP2 Gene
External Ids for TNFAIP2 Gene
- HGNC: 11895
- Entrez Gene: 7127
- Ensembl: ENSG00000185215
- OMIM: 603300
- UniProtKB: Q03169
Previous GeneCards Identifiers for TNFAIP2 Gene
- GC14P100983
- GC14P097408
- GC14P101579
- GC14P101582
- GC14P102662
- GC14P103592
- GC14P083771
- GC14P103123
- GC14P103533
- GC14P103764
- GC14P103953
- GC14P104319
- GC14P103204
- GC14P103281
- GC14P103371
Summaries for TNFAIP2 Gene
-
This gene was identified as a gene whose expression can be induced by the tumor necrosis factor alpha (TNF) in umbilical vein endothelial cells. The expression of this gene was shown to be induced by retinoic acid in a cell line expressing a oncogenic version of the retinoic acid receptor alpha fusion protein, which suggested that this gene may be a retinoic acid target gene in acute promyelocytic leukemia. [provided by RefSeq, Jul 2008]
GeneCards Summary for TNFAIP2 Gene
TNFAIP2 (TNF Alpha Induced Protein 2) is a Protein Coding gene. Diseases associated with TNFAIP2 include Acute Promyelocytic Leukemia. Gene Ontology (GO) annotations related to this gene include SNARE binding. An important paralog of this gene is EXOC3L2.
UniProtKB/Swiss-Prot Summary for TNFAIP2 Gene
-
May play a role as a mediator of inflammation and angiogenesis.
Additional gene information for TNFAIP2 Gene
- HGNC(11895)
- Entrez Gene(7127)
- Ensembl(ENSG00000185215)
- OMIM(603300)
- UniProtKB(Q03169)
- Open Targets Platform(ENSG00000185215)
- Monarch Initiative
- Search for TNFAIP2 at DataMed
- Search for TNFAIP2 at HumanCyc
No data available for CIViC Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , Rfam classification and piRNA Summary for TNFAIP2 Gene
Genomics for TNFAIP2 Gene
GeneHancer (GH) Regulatory Elements Pubs
Promoters and enhancers for TNFAIP2 Gene
- Elite GeneHancer and/or Elite GeneHancer-gene association
Download GeneHancer data from 2017 publication |
Request up-to-date GeneHancer data (full dataset)
GeneHancers around TNFAIP2 on the GeneHancer Hub at the UCSC Golden Path
Cistromic (ChIP-Seq) regulation report from SPP (The Signaling Pathways Project) for TNFAIP2
- Top Transcription factor binding sites by QIAGEN in the TNFAIP2 gene promoter:
-
- c-Myb
- CRE-BP1
- GR
- GR-alpha
- HSF1 (long)
- HSF1short
- ITF-2
- Lmo2
- SRF
- Tal-1beta
Genomic Locations for TNFAIP2 Gene
Genomic Locations for TNFAIP2 Gene
- chr14:103,121,175-103,137,439
- (GRCh38/hg38)
- Size:
- 16,265 bases
- Orientation:
- Plus strand
- chr14:103,589,779-103,603,776
- (GRCh37/hg19)
- Size:
- 13,998 bases
- Orientation:
- Plus strand
Genomic View for TNFAIP2 Gene
Genes around TNFAIP2 on UCSC Golden Path with GeneCards custom track
- Cytogenetic band:
-
- 14q32.32 by HGNC
- 14q32.32 by Entrez Gene
- 14q32.32 by Ensembl
TNFAIP2 Gene in genomic location: bands according to
Ensembl, locations according to GeneLoc
(and/or Entrez Gene and/or Ensembl if different)
Genomic Neighborhood
• Exon Structure
• Gene Density
RefSeq DNA sequence for TNFAIP2 Gene
Proteins for TNFAIP2 Gene
-
Protein details for TNFAIP2 Gene (UniProtKB/Swiss-Prot)
- Protein Symbol:
- Q03169-TNAP2_HUMAN
- Recommended name:
- Tumor necrosis factor alpha-induced protein 2
- Protein Accession:
- Q03169
- Q86VI0
Protein attributes for TNFAIP2 Gene
- Size:
- 654 amino acids
- Molecular mass:
- 72661 Da
- Quaternary structure:
- No Data Available
Protein Expression for TNFAIP2 Gene
Post-translational modifications for TNFAIP2 Gene
Other Protein References for TNFAIP2 Gene
Antibody Products
- G Biosciences Immunotag™ TNAP2 Antibody
- GeneTex Anti-TNFAIP2 antibody [C1C3]
-
Custom Antibody ServicesOriGene Antibodies for TNFAIP2
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-
Abcam antibodies for TNFAIP2
- Invitrogen Antibodies for TNFAIP2 (AFLGC-TNFAIP2)
-
Custom Antibody ServicesProSci Antibodies for TNFAIP2
-
Santa Cruz Biotechnology (SCBT) Antibodies for TNFAIP2
Protein Products
- Search Origene for Purified Proteins, MassSpec and Protein Over-expression Lysates for TNFAIP2
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- antibodies-online: Show 4 available TNFAIP2 Proteins ranked by validation data
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Quality Products:
-
Signalway Proteins for TNFAIP2
-
Abcam proteins for TNFAIP2
Assay Products
- antibodies-online: Show 17 available TNFAIP2 Elisa Kits ranked by validation data
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Quality Products:
No data available for DME Specific Peptides for TNFAIP2 Gene
Domains & Families for TNFAIP2 Gene
Gene Families for TNFAIP2 Gene
- Human Protein Atlas (HPA):
-
- Cancer-related genes
- Plasma proteins
- Predicted intracellular proteins
- Transporters
Protein Domains for TNFAIP2 Gene
- InterPro:
- Blocks:
-
- Exocyst complex component Sec6
- ProtoNet:
Suggested Antigen Peptide Sequences for TNFAIP2 Gene
- GenScript: Design optimal peptide antigens:
-
- TNFAIP2 protein (A1A584_HUMAN)
- Primary response gene B94 protein (TNAP2_HUMAN)
Graphical View of Domain Structure for InterPro Entry
Q03169- Family:
-
- Belongs to the SEC6 family.
Function for TNFAIP2 Gene
Molecular function for TNFAIP2 Gene
- UniProtKB/Swiss-Prot Function:
- May play a role as a mediator of inflammation and angiogenesis.
- UniProtKB/Swiss-Prot Induction:
- By TNF and other proinflammatory factors.
- GENATLAS Biochemistry:
- tumor necrosis factor alpha,inducible primary response,2
Phenotypes From GWAS Catalog for TNFAIP2 Gene
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0000149 | SNARE binding | IBA | 21873635 |
Phenotypes for TNFAIP2 Gene
- GenomeRNAi human phenotypes for TNFAIP2:
-
- Increased vaccinia virus (VACV) infection
- no effect
- Decreased vaccinia virus (VACV) infection
- Increased IL-8 secretion
- Decreased shRNA abundance
- Increased NF-kappaB reporter expression
- Decreased Hepatitis C virus replication
- Increased HPV18 LCR reporter activity
- Upregulation of NF-kappaB pathway after LMP1 stimulation
Animal Model Products
- Taconic Biosciences: Generate A Custom CRISPR Mouse Model For Your Study
CRISPR Products
- Applied Biological Materials (abm): CRISPR Clones for TNFAIP2 - Select products 50% OFF >
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-
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-
Santa Cruz Biotechnology (SCBT) CRISPR for TNFAIP2
miRNA for TNFAIP2 Gene
- miRTarBase miRNAs that target TNFAIP2
-
- hsa-miR-30a-5p (MIRT005196)
- hsa-miR-335-5p (MIRT018025)
- hsa-miR-155-5p (MIRT020719)
- hsa-miR-7-5p (MIRT025752)
- hsa-miR-16-5p (MIRT031757)
- bta-miR-10a (MIRT053802)
- bta-miR-145 (MIRT053912)
- hsa-miR-34b-5p (MIRT395048)
- hsa-miR-449c-5p (MIRT395050)
- hsa-miR-940 (MIRT395051)
- hsa-miR-1910-3p (MIRT395052)
- hsa-miR-2682-5p (MIRT395053)
- hsa-miR-6511a-5p (MIRT395058)
- hsa-miR-6808-5p (MIRT395059)
- hsa-miR-6893-5p (MIRT395060)
- hsa-miR-500a-3p (MIRT495477)
- hsa-miR-6084 (MIRT495478)
- hsa-miR-6069 (MIRT495479)
- hsa-miR-298 (MIRT495480)
- hsa-miR-6804-3p (MIRT495481)
- hsa-miR-6837-5p (MIRT495482)
- hsa-miR-4685-5p (MIRT495483)
- hsa-miR-1306-5p (MIRT495484)
- hsa-miR-3130-3p (MIRT496161)
- hsa-miR-8066 (MIRT712692)
- hsa-miR-184 (MIRT735194)
miRNA Products
Inhibitory RNA Products
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Clone Products
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Cell Line Products
-
Horizon Cell Lines for TNFAIP2
No data available for Enzyme Numbers (IUBMB) , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for TNFAIP2 Gene
Localization for TNFAIP2 Gene
| Compartment | Confidence |
|---|---|
| extracellular | 4 |
| nucleus | 3 |
| cytosol | 2 |
| plasma membrane | 1 |
| cytoskeleton | 1 |
| mitochondrion | 1 |
| peroxisome | 1 |
| endoplasmic reticulum | 1 |
| endosome | 1 |
| lysosome | 1 |
- Cytosol (2)
- Golgi apparatus (2)
- Nuclear membrane (2)
- Nucleoplasm (2)
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0000145 | exocyst | IBA | 21873635 |
| GO:0005615 | extracellular space | TAS | 1374453 |
No data available for Subcellular locations from UniProtKB/Swiss-Prot for TNFAIP2 Gene
Pathways & Interactions for TNFAIP2 Gene
Interacting Proteins for TNFAIP2 Gene
Selected Interacting proteins:
Q03169-TNAP2_HUMAN
ENSP00000452634
for TNFAIP2 Gene via
UniProtKB
MINT
STRING
IID
GPS-Prot Interaction Network for TNFAIP2
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0001525 | angiogenesis | IEA | -- |
| GO:0006887 | exocytosis | IBA | 21873635 |
| GO:0007275 | multicellular organism development | IEA | -- |
| GO:0030154 | cell differentiation | IEA | -- |
| GO:0051601 | exocyst localization | IBA | 21873635 |
No data available for Pathways by source and SIGNOR curated interactions for TNFAIP2 Gene
Transcripts for TNFAIP2 Gene
mRNA/cDNA for TNFAIP2 Gene
- 3 REFSEQ mRNAs :
- 8 NCBI additional mRNA sequence :
- 11 Ensembl transcripts including schematic representations, and UCSC links to gene/alias where relevant :
-
- ENST00000333007 4175 nts (view in UCSC)
- ENST00000558056 421 nts (view in UCSC)
- ENST00000559195 572 nts (view in UCSC)
- ENST00000559255 1410 nts (view in UCSC)
- ENST00000559406 1799 nts (view in UCSC)
CRISPR Products
- Applied Biological Materials (abm): CRISPR Clones for TNFAIP2 - Select products 50% OFF >
- * TNFAIP2 CRISPR as ready-to-use vector or virus: ORF | Lenti- | Adeno- | AAV- | Protein Vector - Browse All
- * Gene synthesis, site-directed mutagenesis, subcloning, and more services - Browse All
-
OriGene CRISPR knockouts for TNFAIP2
- Search GeneCopoeia for CRISPR/Cas9 clones, lentivirus and AAV products for TNFAIP2
-
Santa Cruz Biotechnology (SCBT) CRISPR for TNFAIP2
miRNA Products
Inhibitory RNA Products
- Origene shrna, sirna, and RNAi products in human, mouse, rat for TNFAIP2
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Clone Products
- Applied Biological Materials (abm): Clones for TNFAIP2 - Select products 50% OFF >
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- Sino Biological Human cDNA Clone for TNFAIP2
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| ExUns: | 1 | ^ | 2 | ^ | 3 | ^ | 4a | · | 4b | ^ | 5 | ^ | 6 | ^ | 7 | ^ | 8a | · | 8b | ^ | 9 | ^ | 10 | ^ | 11 | ^ | 12a | · | 12b |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| SP1: | |||||||||||||||||||||||||||||
| SP2: | |||||||||||||||||||||||||||||
| SP3: | - |
Relevant External Links for TNFAIP2 Gene
- GeneLoc Exon Structure for
- TNFAIP2
Expression for TNFAIP2 Gene
mRNA expression in embryonic tissues and stem cells from LifeMap Discovery
-
Blood (Hematopoietic System)
- Granulocytes Peripheral Blood
- Monocytes Peripheral Blood
- Peripheral blood-derived hematopoietic stem cells (family)
- Peripheral blood-derived hematopoietic stem cells
-
Skeletal Muscle (Muscoskeletal System)
- Muscle Progenitor Cells Mandibular Arch Muscles
- Muscle Progenitor Cells Hyoid Arch Muscles
- Bone (Muscoskeletal System)
-
Heart (Cardiovascular System)
- Endocardial Tube Cells Endocardium
-
Lung (Respiratory System)
mRNA differential expression in normal tissues according to GTEx for TNFAIP2 Gene
This gene is overexpressed in Whole Blood (x4.2).
This gene is overexpressed in Lymph node (8.1), Spleen (7.9), and Bone (7.7).
Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, MaxQB, and MOPED for TNFAIP2 Gene
- Elite partner
Transcriptomic regulation report from SPP (The Signaling Pathways Project) for TNFAIP2
SOURCE GeneReport for Unigene cluster for TNFAIP2 Gene:
Hs.525607Evidence on tissue expression from TISSUES for TNFAIP2 Gene
- Heart(4.5)
- Lung(3.4)
- Spleen(2.9)
- Intestine(2.8)
- Lymph node(2.7)
- Blood(2.6)
- Skin(2.6)
- Bone marrow(2.6)
- Nervous system(2.5)
- Liver(2.4)
- Kidney(2.2)
- Muscle(2.1)
- Stomach(2.1)
- Adrenal gland(2)
Primer Products
-
OriGene qPCR primer pairs for TNFAIP2
Gene Expression Assay Products
No data available for mRNA Expression by UniProt/SwissProt and Phenotype-based relationships between genes and organs from Gene ORGANizer for TNFAIP2 Gene
Orthologs for TNFAIP2 Gene
This gene was present in the common ancestor of animals.
| Organism | Taxonomy | Gene | Similarity | Type | Details |
|---|---|---|---|---|---|
| Chimpanzee (Pan troglodytes) |
Mammalia | TNFAIP2 30 31 |
|
OneToOne | |
| Dog (Canis familiaris) |
Mammalia | TNFAIP2 30 31 |
|
OneToOne | |
| Cow (Bos Taurus) |
Mammalia | TNFAIP2 30 31 |
|
OneToOne | |
| Mouse (Mus musculus) |
Mammalia | Tnfaip2 30 17 31 |
|
OneToOne | |
| Rat (Rattus norvegicus) |
Mammalia | Tnfaip2 30 |
|
||
| Oppossum (Monodelphis domestica) |
Mammalia | TNFAIP2 31 |
|
OneToOne | |
| Platypus (Ornithorhynchus anatinus) |
Mammalia | TNFAIP2 31 |
|
OneToOne | |
| Chicken (Gallus gallus) |
Aves | TNFAIP2 30 31 |
|
OneToOne | |
| Lizard (Anolis carolinensis) |
Reptilia | TNFAIP2 31 |
|
OneToOne | |
| Tropical Clawed Frog (Silurana tropicalis) |
Amphibia | tnfaip2 30 |
|
||
| Zebrafish (Danio rerio) |
Actinopterygii | tnfaip2b 30 31 31 |
|
OneToMany | |
| tnfaip2a 31 |
|
OneToMany | |||
| Fruit Fly (Drosophila melanogaster) |
Insecta | sec6 31 |
|
OneToMany | |
| Worm (Caenorhabditis elegans) |
Secernentea | sec-6 31 |
|
OneToMany | |
| Sea Squirt (Ciona savignyi) |
Ascidiacea | -- 31 |
|
OneToMany |
- Species where no ortholog for TNFAIP2 was found in the sources mined by GeneCards:
-
- A. gosspyii yeast (Eremothecium gossypii)
- Actinobacteria (Mycobacterium tuberculosis)
- African clawed frog (Xenopus laevis)
- African malaria mosquito (Anopheles gambiae)
- Alicante grape (Vitis vinifera)
- Alpha proteobacteria (Wolbachia pipientis)
- Amoeba (Dictyostelium discoideum)
- Archea (Pyrococcus horikoshii)
- Baker's yeast (Saccharomyces cerevisiae)
- Barley (Hordeum vulgare)
- Beta proteobacteria (Neisseria meningitidis)
- Bread mold (Neurospora crassa)
- Chromalveolata (Phytophthora infestans)
- Common water flea (Daphnia pulex)
- Corn (Zea mays)
- E. coli (Escherichia coli)
- Filamentous fungi (Aspergillus nidulans)
- Firmicute Bacteria (Streptococcus pneumoniae)
- Fission Yeast (Schizosaccharomyces pombe)
- Green Algae (Chlamydomonas reinhardtii)
- Honey Bee (Apis mellifera)
- K. Lactis Yeast (Kluyveromyces lactis)
- Loblloly Pine (Pinus taeda)
- Malaria Parasite (Plasmodium falciparum)
- Medicago Trunc (Medicago Truncatula)
- Moss (Physcomitrella patens)
- Orangutan (Pongo pygmaeus)
- Pig (Sus scrofa)
- Rainbow Trout (Oncorhynchus mykiss)
- Rice (Oryza sativa)
- Rice Blast Fungus (Magnaporthe grisea)
- Schistosome Parasite (Schistosoma mansoni)
- Sea Anemone (Nematostella vectensis)
- Sea Vase (Ciona intestinalis)
- Sea Urchin (Strongylocentrotus purpuratus)
- Sorghum (Sorghum bicolor)
- Soybean (Glycine max)
- Stem Rust Fungus (Puccinia graminis)
- Sugarcane (Saccharum officinarum)
- Thale Cress (Arabidopsis thaliana)
- Tomato (Lycopersicon esculentum)
- Toxoplasmosis (Toxoplasma gondii)
- Trichoplax (Trichoplax adhaerens)
- Wheat (Triticum aestivum)
Evolution for TNFAIP2 Gene
- ENSEMBL:
- Gene Tree for TNFAIP2 (if available)
- TreeFam:
- Gene Tree for TNFAIP2 (if available)
- Aminode:
- Evolutionary constrained regions (ECRs) for TNFAIP2: view image
Paralogs for TNFAIP2 Gene
Variants for TNFAIP2 Gene
Sequence variations, with clinical significance, from ClinVar and Humsavar, with links to dbSNP for TNFAIP2 Gene
| SNP ID | Clinical significance and condition | Chr 14 pos | Variation | AA Info | Type |
|---|---|---|---|---|---|
| 715671 | Benign: not provided | 103,126,556(+) | G/A | SYNONYMOUS_VARIANT | |
| 734189 | Benign: not provided | 103,133,719(+) | C/T | MISSENSE_VARIANT | |
| 773855 | Benign: not provided | 103,126,688(+) | C/A | SYNONYMOUS_VARIANT | |
| 773856 | Benign: not provided | 103,132,800(+) | C/G | SYNONYMOUS_VARIANT | |
| rs1132339 | - | p.Gln282Glu |
| Variant ID | Type | Subtype | PubMed ID |
|---|---|---|---|
| dgv141e215 | CNV | deletion | 23714750 |
| dgv3935n54 | CNV | loss | 21841781 |
| dgv3936n54 | CNV | loss | 21841781 |
| dgv3937n54 | CNV | loss | 21841781 |
| esv1662663 | CNV | deletion | 17803354 |
| esv2387988 | CNV | deletion | 18987734 |
| esv2749162 | CNV | deletion | 23290073 |
| esv3187495 | CNV | deletion | 24192839 |
| esv995383 | CNV | deletion | 20482838 |
| nsv565970 | CNV | loss | 21841781 |
| nsv565971 | CNV | loss | 21841781 |
| nsv565972 | CNV | loss | 21841781 |
| nsv832882 | CNV | loss | 17160897 |
| nsv84480 | CNV | deletion | 16902084 |
| nsv84629 | CNV | deletion | 16902084 |
| nsv9168 | CNV | loss | 18304495 |
| nsv952257 | CNV | deletion | 24416366 |
Residual Variation Intolerance Score:
29.1% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score:
3.20;
52.12% of all genes are more intolerant (likely to be disease-causing)
Additional Variant Information for TNFAIP2 Gene
SNP Genotyping and Copy Number Assay Products
No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for TNFAIP2 Gene
Disorders for TNFAIP2 Gene
| Disorder | Aliases | PubMed IDs |
|---|---|---|
| acute promyelocytic leukemia |
|
|
Search TNFAIP2 in MalaCards
View complete list of genes associated with diseases
Additional Disease Information for TNFAIP2
- Genetic Association Database
- (GAD)
- Human Genome Epidemiology Navigator
- (HuGE)
- ATLAS of Genetics and Cytogenetics in Oncology and Haematology
- Open Targets Platform
No data available for UniProtKB/Swiss-Prot and Genatlas for TNFAIP2 Gene
Publications for TNFAIP2 Gene
- Cloning of a novel tumor necrosis factor-alpha-inducible primary response gene that is differentially expressed in development and capillary tube-like formation in vitro. (PMID: 1374453) Sarma V … Dixit VM (Journal of immunology (Baltimore, Md. : 1950) 1992) 2 3 4 23
- Variation at the NFATC2 locus increases the risk of thiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) study. (PMID: 20628086) Bailey SD … DREAM investigators (Diabetes care 2010) 3 41
- Evaluation of candidate stromal epithelial cross-talk genes identifies association between risk of serous ovarian cancer and TERT, a cancer susceptibility "hot-spot". (PMID: 20628624) Johnatty SE … Australian Cancer Study (Ovarian Cancer) (PLoS genetics 2010) 3 41
- SNPs in genes coding for ROS metabolism and signalling in association with docetaxel clearance. (PMID: 20157331) Edvardsen H … Kristensen VN (The pharmacogenomics journal 2010) 3 41
- Genetic associations of 115 polymorphisms with cancers of the upper aerodigestive tract across 10 European countries: the ARCAGE project. (PMID: 19339270) Canova C … Brennan P (Cancer research 2009) 3 41
ExternalLinks
Products for TNFAIP2 Gene
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- Search GeneCopoeia for ORF cDNA, lentivirus, AAV viral particles and/or promoter clone products for TNFAIP2
- Search GeneCopoeia for miRNA 3'UTR Target clone products for TNFAIP2
- Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for TNFAIP2
Sources for TNFAIP2 Gene
- (1) GeneCards
- (2) HGNC
- (3) NCBI Entrez Gene
- (4) UniProtKB/Swiss-Prot
- (5) Ensembl
- (6) OMIM
- (7) GeneLoc
- (8) Gene Wiki
- (9) UCSC
- (10) PhosphoSitePlus
- (11) Cell Signaling Technology
- (12) GO
- (13) UniProtKB/TrEMBL
- (14) InterPro
- (15) ProtoNet
- (16) Blocks
- (17) MGI
- (18) IUBMB
- (19) KEGG
- (20) MINT
- (21) STRING
- (22) IntAct
- (23) Novoseek
- (24) PharmGKB
- (25) DrugBank
- (26) HMDB
- (27) ASD
- (28) SAGE
- (29) SOURCE
- (30) HomoloGene
- (31) PanEnsembl
- (32) euGenes
- (33) SGD
- (34) FlyBase
- (35) WormBase
- (36) Pseudogene
- (37) DGV
- (38) dbSNP
- (39) GenAtlas
- (40) HGMD
- (41) GAD
- (42) BGMUT
- (43) HuGE
- (44) Atlas
- (45) GenBank
- (46) HORDE
- (47) HUGE
- (48) IMGT
- (49) Leiden
- (50) miRBase
- (51) DME
- (52) OriGene
- (53) PubMed
- (54) R&D Systems
- (55) TGDB
- (56) Tocris
- (57) Abcam
- (58) Novus Biologicals
- (59) ProSpec
- (60) Sino Biological
- (61) GenScript
- (62) Qiagen
- (63) OCA
- (64) Proteopedia
- (65) MOPED
- (66) neXtProt
- (67) Reactome
- (68) GeneGo (Thomson Reuters)
- (69) DISEASES
- (70) SIMAP
- (71) GenomeRNAi
- (72) LifeMap
- (73) miRTarBase
- (74) MalaCards
- (75) Invitrogen
- (76) BitterDB
- (77) ESI-BIO
- (78) RefSeq
- (79) BioSystems
- (80) MaxQB
- (81) IUPHAR
- (82) BioGPS
- (83) Illumina
- (84) COMPARTMENTS
- (85) HOMER
- (86) PaxDb
- (87) ApexBio
- (88) Addgene
- (89) antibodies-online
- (90) CYP
- (91) NONCODE
- (92) TreeFam
- (93) PathCards
- (94) GeneReviews
- (95) GeneTex
- (96) Taconic Biosciences
- (97) GTEx
- (98) ProteomicsDB
- (99) SCBT
- (100) DGIdb
- (101) ClinicalTrials
- (102) RVIS
- (103) SIGNOR
- (104) diseasecard
- (105) NIH Rare Diseases
- (106) Orphanet
- (107) UMLS
- (108) GTR
- (109) Disease Ontology
- (110) Genetics Home Reference
- (111) MeSH
- (112) MedlinePlus
- (113) CDC
- (114) NINDS
- (115) NCBI Bookshelf
- (116) ClinVar
- (117) Gene Damage Index
- (118) HPO
- (119) UDN
- (120) VISTA
- (121) FANTOM5
- (122) ENCODE
- (123) ProSci
- (124) Horizon
- (125) The Signaling Pathways Project (SPP)
- (126) IID
- (127) VectorBuilder
- (128) SNPedia
- (129) BRCA Exchange
- (130) CIViC
- (131) ProteoGenix
- (132) dbSUPER
- (133) TISSUES
- (134) Gene ORGANizer
- (135) abm
- (136) Human Protein Atlas
- (137) GWAS Catalog
- (138) Monarch Initiative
- (139) DataMed
- (140) HumanCyc
- (141) UCNEbase
- (142) EPDnew
- (143) Applied Biosystems
- (144) GlyConnect
- (145) Aminode
- (146) GeneCopoeia
- (147) GPS-Prot
- (148) RNACentral
- (149) LncRNADisease
- (150) LOVD
- (151) miR2Disease
- (152) DiseaseEnhancer
- (153) Boster Bio
- (154) Biorbyt
- (155) Biocompare
- (156) Mastermind
- (157) CTD^2 Dashboard
- (158) CraniofacialAtlas
- (159) GeneImprint
- (160) Synthego
- (161) ENA
- (162) GtRNAdb
- (163) LncBase
- (164) LncBook
- (165) LNCipedia
- (166) Modomics
- (167) PDBe
- (168) Rfam
- (169) SILVA
- (170) snOPY
- (171) SRPDB
- (172) GENCODE
- (173) TarBase
- (174) Signalway Antibody
- (175) Open Targets Platform
- (176) 5SRRNADB
- (177) snoDB
- (178) MirGeneDB