Aliases for TMX4 Gene
External Ids for TMX4 Gene
Previous HGNC Symbols for TMX4 Gene
Previous GeneCards Identifiers for TMX4 Gene
This gene encodes a member of the disulfide isomerase (PDI) family of endoplasmic reticulum (ER) proteins that catalyze protein folding and thiol-disulfide interchange reactions. The encoded protein has an N-terminal ER-signal sequence, a catalytically active thioredoxin domain, one transmembrane domain and C-terminal ASP/GLU-rich calcium binding domain. Unlike most members of this gene family, it lacks a C-terminal ER-retention sequence. The encoded protein has been shown to have reductase activity in vitro. [provided by RefSeq, Jan 2017]
GeneCards Summary for TMX4 Gene
TMX4 (Thioredoxin Related Transmembrane Protein 4) is a Protein Coding gene. Gene Ontology (GO) annotations related to this gene include protein disulfide isomerase activity. An important paralog of this gene is TMX1.