Aliases for TMTC1 Gene
Aliases for TMTC1 Gene
External Ids for TMTC1 Gene
- HGNC: 24099
- Entrez Gene: 83857
- Ensembl: ENSG00000133687
- OMIM: 615855
- UniProtKB: Q8IUR5
Previous GeneCards Identifiers for TMTC1 Gene
- GC12M029551
- GC12M029547
- GC12M029548
- GC12M029549
- GC12M029653
Summaries for TMTC1 Gene
GeneCards Summary for TMTC1 Gene
TMTC1 (Transmembrane And Tetratricopeptide Repeat Containing 1) is a Protein Coding gene. Diseases associated with TMTC1 include Spinal Cord Disease and Brown-Sequard Syndrome. An important paralog of this gene is TMTC4.
Additional gene information for TMTC1 Gene
- Monarch Initiative
- Search for TMTC1 at DataMed
- Search for TMTC1 at HumanCyc
No data available for Entrez Gene Summary , CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for TMTC1 Gene
Genomics for TMTC1 Gene
GeneHancer (GH) Regulatory Elements for TMTC1 Gene
Promoters and enhancers for TMTC1 Gene
| GeneHancer (GH) Identifier | GH Type | GH Score |
GH Sources | Gene Association Score | Total Score | TSS distance (kb) | Number of Genes Away | Size (kb) | Transcription Factor Binding Sites |
Gene Targets |
|---|---|---|---|---|---|---|---|---|---|---|
| GH12I029781 | Promoter/Enhancer | 2.1 | EPDnew Ensembl ENCODE dbSUPER | 578.5 | +1.7 | 1701 | 3.6 | PKNOX1 ARNT SIN3A FEZF1 GLIS2 ATF7 JUNB REST MAFF STAT3 | TMTC1 GC12P029760 | |
| GH12I029768 | Enhancer | 0.8 | ENCODE dbSUPER | 29.2 | +15.7 | 15696 | 1.5 | NR2F1 CEBPB DPF2 EP300 IKZF1 ZFP36 FOS HNF4A IKZF2 | TMTC1 GC12P029760 | |
| GH12I029739 | Enhancer | 1.2 | Ensembl ENCODE dbSUPER | 8 | +42.4 | 42435 | 6.5 | FEZF1 ZEB1 ZNF121 ZNF366 SCRT2 ZNF362 USF2 CEBPB TSHZ1 ZEB2 | TMTC1 GC12M029751 PIR32814 GC12M029727 | |
| GH12I029691 | Enhancer | 1.1 | FANTOM5 Ensembl ENCODE | 7.2 | +93.3 | 93298 | 0.9 | PKNOX1 SMAD1 EBF1 ELF1 DPF2 BCL11A IKZF1 POU5F1 NBN IKZF2 | TMTC1 GC12P029725 RPL21P99 | |
| GH12I029732 | Enhancer | 0.6 | ENCODE dbSUPER | 11.2 | +52.3 | 52336 | 0.2 | OSR2 NFIC NFIB | TMTC1 PIR32814 GC12M029727 GC12M029751 |
- Elite GeneHancer and/or Elite GeneHancer-gene association
Download GeneHancer data dump
GeneHancers around TMTC1 on UCSC Golden Path with GeneCards custom track
Regulatory Element Products
Genomic Locations for TMTC1 Gene
Genomic Locations for TMTC1 Gene
- chr12:29,500,813-29,784,759
- (GRCh38/hg38)
- Size:
- 283,947 bases
- Orientation:
- Minus strand
- chr12:29,653,746-29,937,692
- (GRCh37/hg19)
Genomic View for TMTC1 Gene
Genes around TMTC1 on UCSC Golden Path with GeneCards custom track
- Cytogenetic band:
-
- 12p11.22 by Ensembl
- 12p11.22 by Entrez Gene
- 12p11.22 by HGNC
TMTC1 Gene in genomic location: bands according to
Ensembl, locations according to GeneLoc
(and/or Entrez Gene and/or Ensembl if different)
Genomic Neighborhood
• Exon Structure
• Gene Density
RefSeq DNA sequence for TMTC1 Gene
Proteins for TMTC1 Gene
-
Protein details for TMTC1 Gene (UniProtKB/Swiss-Prot)
- Protein Symbol:
- Q8IUR5-TMTC1_HUMAN
- Recommended name:
- Transmembrane and TPR repeat-containing protein 1
- Protein Accession:
- Q8IUR5
- D0EP37
- F5H8B5
- Q6PIU4
- Q6ZSM5
- Q96N52
- Q9BXM2
Protein attributes for TMTC1 Gene
- Size:
- 882 amino acids
- Molecular mass:
- 98847 Da
- Quaternary structure:
-
- May interact with FAM168B.
- SequenceCaution:
-
- Sequence=AAK32121.1; Type=Erroneous initiation; Note=Translation N-terminally extended.; Evidence={ECO:0000305};
Protein Expression for TMTC1 Gene
Post-translational modifications for TMTC1 Gene
- Glycosylation at posLast=7676
Other Protein References for TMTC1 Gene
- ENSEMBL proteins:
- REFSEQ proteins:
Antibody Products
- Novus Biologicals Antibodies for TMTC1
- Invitrogen Antibodies for TMTC1
- GeneTex TMTC1 antibody for TMTC1
Protein Products
-
OriGene Purified Proteins for TMTC1
- Search Origene for MassSpec and Protein Over-expression Lysates for TMTC1
- Origene Custom Protein Services for TMTC1
- Search GeneTex for Proteins for TMTC1
-
ProSci Proteins for TMTC1
-
Abcam proteins for TMTC1
Assay Products
No data available for DME Specific Peptides for TMTC1 Gene
Domains & Families for TMTC1 Gene
Gene Families for TMTC1 Gene
- HGNC:
- Human Protein Atlas (HPA):
-
- Predicted membrane proteins
Protein Domains for TMTC1 Gene
- InterPro:
- ProtoNet:
Suggested Antigen Peptide Sequences for TMTC1 Gene
- GenScript: Design optimal peptide antigens:
Graphical View of Domain Structure for InterPro Entry
Q8IUR5- Family:
-
- Belongs to the TMTC family.
Function for TMTC1 Gene
Phenotypes From GWAS Catalog for TMTC1 Gene
Phenotypes for TMTC1 Gene
Animal Model Products
- Taconic Biosciences: Generate A Custom CRISPR Mouse Model For Your Study
- Cyagen custom Knockout/knockin (KOKI) mouse models for TMTC1
-
-
ViGene Biosciences lentiviral particle packaged cDNA for TMTC1 gene
-
ViGene Biosciences ready-to-package AAV shRNAs for TMTC1 gene
- Search ViGene Biosciences for TMTC1
CRISPR Products
-
OriGene CRISPR knockouts for TMTC1
- genomics-online: gRNA clones - Search results for available TMTC1 gene related products
- Applied Biological Materials CRISPR for TMTC1
-
Vectors and viruses for KO, Activation, Repression, and more
-
Santa Cruz Biotechnology (SCBT) CRISPR for TMTC1
- GenScript: Design CRISPR guide RNA sequences for TMTC1
miRNA for TMTC1 Gene
- miRTarBase miRNAs that target TMTC1
-
- hsa-mir-193b-3p (MIRT016438)
- hsa-mir-320a (MIRT044820)
- hsa-mir-27b-3p (MIRT046239)
- hsa-mir-3157-5p (MIRT064121)
- hsa-mir-1238-3p (MIRT491109)
- hsa-mir-6749-3p (MIRT491110)
- hsa-mir-670-3p (MIRT491111)
- hsa-mir-6792-3p (MIRT491112)
- hsa-mir-4691-5p (MIRT491113)
- hsa-mir-627-3p (MIRT491114)
- hsa-mir-5695 (MIRT491115)
- hsa-mir-4666a-3p (MIRT491116)
- hsa-mir-7849-3p (MIRT491117)
- hsa-mir-3910 (MIRT491118)
- hsa-mir-374b-5p (MIRT532075)
- hsa-mir-374a-5p (MIRT532076)
- hsa-mir-655-3p (MIRT532077)
- hsa-mir-374c-5p (MIRT532078)
- hsa-mir-5692c (MIRT532079)
- hsa-mir-5692b (MIRT532080)
- hsa-mir-369-3p (MIRT532081)
- hsa-mir-335-3p (MIRT614575)
- hsa-mir-1305 (MIRT614576)
- hsa-mir-607 (MIRT614577)
- hsa-mir-3613-3p (MIRT614578)
- hsa-mir-561-3p (MIRT614579)
- hsa-mir-548x-5p (MIRT616028)
- hsa-mir-548g-5p (MIRT616029)
- hsa-mir-548f-5p (MIRT616030)
- hsa-mir-548aj-5p (MIRT616031)
- hsa-mir-548p (MIRT616032)
- hsa-mir-887-5p (MIRT665709)
- hsa-mir-6780a-5p (MIRT665710)
- hsa-mir-6779-5p (MIRT665711)
- hsa-mir-3689c (MIRT665712)
- hsa-mir-3689b-3p (MIRT665713)
- hsa-mir-3689a-3p (MIRT665714)
- hsa-mir-30b-3p (MIRT665715)
- hsa-mir-1273h-5p (MIRT665716)
- hsa-mir-6788-5p (MIRT665717)
- hsa-mir-30c-2-3p (MIRT665718)
- hsa-mir-30c-1-3p (MIRT665719)
- hsa-mir-6778-5p (MIRT665720)
- hsa-mir-1233-5p (MIRT665721)
- hsa-mir-6799-5p (MIRT665722)
- hsa-mir-6883-5p (MIRT665723)
- hsa-mir-6785-5p (MIRT665724)
- hsa-mir-4728-5p (MIRT665725)
- hsa-mir-149-3p (MIRT665726)
- hsa-mir-7106-5p (MIRT665727)
- hsa-mir-6894-5p (MIRT665728)
- hsa-mir-7160-5p (MIRT665729)
- hsa-mir-6134 (MIRT665730)
- hsa-mir-7854-3p (MIRT665731)
- hsa-mir-6884-5p (MIRT665732)
- hsa-mir-485-5p (MIRT665733)
- hsa-mir-7162-3p (MIRT665734)
- hsa-mir-5088-3p (MIRT665735)
- hsa-mir-665 (MIRT665736)
- hsa-mir-4691-3p (MIRT665737)
- hsa-mir-6866-3p (MIRT665738)
- hsa-mir-188-5p (MIRT665739)
- hsa-mir-4478 (MIRT665740)
- hsa-mir-4419b (MIRT665741)
- hsa-mir-3929 (MIRT665742)
- hsa-mir-4661-3p (MIRT665743)
- hsa-mir-890 (MIRT665744)
- hsa-mir-4715-3p (MIRT715054)
- hsa-mir-3064-3p (MIRT715055)
- hsa-mir-548aw (MIRT715056)
- hsa-mir-19b-3p (MIRT715057)
- hsa-mir-19a-3p (MIRT715058)
- hsa-mir-1468-3p (MIRT715059)
- hsa-mir-125b-2-3p (MIRT715060)
- hsa-mir-454-3p (MIRT715061)
- hsa-mir-4295 (MIRT715062)
- hsa-mir-3666 (MIRT715063)
- hsa-mir-301b-3p (MIRT715064)
- hsa-mir-301a-3p (MIRT715065)
- hsa-mir-130b-3p (MIRT715066)
- hsa-mir-130a-3p (MIRT715067)
- hsa-mir-519c-3p (MIRT715068)
- hsa-mir-519b-3p (MIRT715069)
- hsa-mir-519a-3p (MIRT715070)
- hsa-mir-6776-3p (MIRT715071)
- hsa-mir-497-3p (MIRT715072)
- hsa-mir-548t-3p (MIRT715073)
- hsa-mir-548ap-3p (MIRT715074)
- hsa-mir-548aa (MIRT715075)
miRNA Products
- Search ViGene Biosciences for TMTC1
Inhibitory RNA Products
- Origene RNAi, sirna, and shrna products in human, mouse, rat for TMTC1
- Browse OriGene Inhibitory RNA Products For TMTC1
- genomics-online: shRNA clones - Search results for available TMTC1 gene related products
-
ViGene Biosciences ready-to-package AAV shRNAs for TMTC1 gene
Clone Products
- Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat
- VectorBuilder custom plasmid, inducible vectors for TMTC1
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for TMTC1
-
VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
- genomics-online: cdna clones - Search results for available TMTC1 gene related products
- orf clones - Search results for available TMTC1 gene related products
- Applied Biological Materials Clones for TMTC1
-
Vectors and viruses for ORF, Lenti, Retro, Adenovirus, AAV, and more
Cell Line Products
-
Horizon Cell Lines for TMTC1
-
ViGene Biosciences adenoviral particle packaged cDNA for TMTC1 gene
-
ViGene Biosciences lentiviral particle packaged cDNA for TMTC1 gene
-
ViGene Biosciences ready-to-package AAV shRNAs for TMTC1 gene
No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for TMTC1 Gene
Localization for TMTC1 Gene
Subcellular locations from UniProtKB/Swiss-Prot for TMTC1 Gene
- Membrane; Multi-pass membrane protein.
| Compartment | Confidence |
|---|---|
| plasma membrane | 3 |
| extracellular | 2 |
| mitochondrion | 2 |
| nucleus | 2 |
| cytosol | 2 |
| peroxisome | 1 |
| endoplasmic reticulum | 1 |
- Cytosol (2)
- Nucleoplasm (2)
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0005739 | mitochondrion | IEA | -- |
| GO:0016020 | membrane | IEA | -- |
| GO:0016021 | integral component of membrane | IEA | -- |
Pathways & Interactions for TMTC1 Gene
No Data Available
Interacting Proteins for TMTC1 Gene
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0006396 | RNA processing | IEA | -- |
No data available for Pathways by source and SIGNOR curated interactions for TMTC1 Gene
Transcripts for TMTC1 Gene
mRNA/cDNA for TMTC1 Gene
- (8) REFSEQ mRNAs :
- (12) Additional mRNA sequences :
- (233) Selected AceView cDNA sequences:
- (9) Ensembl transcripts including schematic representations, and UCSC links where relevant :
Unigene Clusters for TMTC1 Gene
CRISPR Products
-
OriGene CRISPR knockouts for TMTC1
- genomics-online: gRNA clones - Search results for available TMTC1 gene related products
- Applied Biological Materials CRISPR for TMTC1
-
Vectors and viruses for KO, Activation, Repression, and more
-
Santa Cruz Biotechnology (SCBT) CRISPR for TMTC1
- GenScript: Design CRISPR guide RNA sequences for TMTC1
miRNA Products
- Search ViGene Biosciences for TMTC1
Inhibitory RNA Products
- Origene RNAi, sirna, and shrna products in human, mouse, rat for TMTC1
- Browse OriGene Inhibitory RNA Products For TMTC1
- genomics-online: shRNA clones - Search results for available TMTC1 gene related products
-
ViGene Biosciences ready-to-package AAV shRNAs for TMTC1 gene
Clone Products
- Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat
- VectorBuilder custom plasmid, inducible vectors for TMTC1
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for TMTC1
-
VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
- genomics-online: cdna clones - Search results for available TMTC1 gene related products
- orf clones - Search results for available TMTC1 gene related products
- Applied Biological Materials Clones for TMTC1
-
Vectors and viruses for ORF, Lenti, Retro, Adenovirus, AAV, and more
| ExUns: | 1 | ^ | 2 | ^ | 3 | ^ | 4 | ^ | 5 | ^ | 6 | ^ | 7 | ^ | 8 | ^ | 9 | ^ | 10 | ^ | 11 | ^ | 12 | ^ | 13 | ^ | 14 | ^ | 15 | ^ | 16a | · | 16b | ^ | 17 | ^ | 18 | ^ | 19a | · | 19b | ^ | 20 | ^ | 21 | ^ | 22 | ^ | 23 | ^ | 24 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| SP1: | - | - | - | - | - | - | - | ||||||||||||||||||||||||||||||||||||||||||||
| SP2: | - | - | - | ||||||||||||||||||||||||||||||||||||||||||||||||
| SP3: | - | - | |||||||||||||||||||||||||||||||||||||||||||||||||
| SP4: | - | ||||||||||||||||||||||||||||||||||||||||||||||||||
| SP5: | - | ||||||||||||||||||||||||||||||||||||||||||||||||||
| SP6: | - |
Expression for TMTC1 Gene
mRNA expression in embryonic tissues and stem cells from LifeMap Discovery
- Mesenchymal Stem Cells (Uncategorized)
- Placenta (Extraembryonic Tissues)
-
Hair (Integumentary System)
- Bulge Stem Cells Bulge
-
Blood (Hematopoietic System)
- Natural Killer Cells Peripheral Blood
-
Kidney (Urinary System)
- Podocytes Podocyte Layer
-
Epithelial Cells
- Podocytes Podocyte Layer
- Brain (Nervous System)
mRNA differential expression in normal tissues according to GTEx for TMTC1 Gene
This gene is overexpressed in Artery - Tibial (x4.1).
This gene is overexpressed in Liver (69.0).
Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, PaxDb, and MOPED for TMTC1 Gene
NURSA nuclear receptor signaling pathways regulating expression of TMTC1 Gene:
TMTC1SOURCE GeneReport for Unigene cluster for TMTC1 Gene:
Hs.401954Evidence on tissue expression from TISSUES for TMTC1 Gene
- Nervous system(4.7)
- Pancreas(4.2)
- Lung(2.4)
Primer Products
-
OriGene qPCR primer pairs for TMTC1
-
OriGene qPCR primer pairs and template standards for TMTC1
- genomics-online: primer clones - Search results for available TMTC1 gene related products
No data available for mRNA Expression by UniProt/SwissProt and Phenotype-based relationships between genes and organs from Gene ORGANizer for TMTC1 Gene
Orthologs for TMTC1 Gene
This gene was present in the common ancestor of chordates.
| Organism | Taxonomy | Gene | Similarity | Type | Details |
|---|---|---|---|---|---|
| chimpanzee (Pan troglodytes) |
Mammalia | TMTC1 33 34 |
|
||
| dog (Canis familiaris) |
Mammalia | TMTC1 33 34 |
|
||
| cow (Bos Taurus) |
Mammalia | TMTC1 33 34 |
|
||
| mouse (Mus musculus) |
Mammalia | Tmtc1 33 16 34 |
|
||
| rat (Rattus norvegicus) |
Mammalia | Tmtc1 33 |
|
||
| platypus (Ornithorhynchus anatinus) |
Mammalia | -- 34 |
|
OneToMany | |
| -- 34 |
|
OneToMany | |||
| -- 34 |
|
OneToMany | |||
| oppossum (Monodelphis domestica) |
Mammalia | TMTC1 34 |
|
OneToOne | |
| chicken (Gallus gallus) |
Aves | TMTC1 33 34 |
|
||
| lizard (Anolis carolinensis) |
Reptilia | TMTC1 34 |
|
OneToOne | |
| tropical clawed frog (Silurana tropicalis) |
Amphibia | tmtc1 33 |
|
||
| zebrafish (Danio rerio) |
Actinopterygii | LOC555449 33 |
|
||
| tmtc1 34 |
|
OneToOne |
- Species where no ortholog for TMTC1 was found in the sources mined by GeneCards:
-
- A. gosspyii yeast (Ashbya gossypii)
- Actinobacteria (Mycobacterium tuberculosis)
- African clawed frog (Xenopus laevis)
- African malaria mosquito (Anopheles gambiae)
- Alicante grape (Vitis vinifera)
- alpha proteobacteria (Wolbachia pipientis)
- amoeba (Dictyostelium discoideum)
- Archea (Pyrococcus horikoshii)
- baker's yeast (Saccharomyces cerevisiae)
- barley (Hordeum vulgare)
- beta proteobacteria (Neisseria meningitidis)
- bread mold (Neurospora crassa)
- Chromalveolata (Phytophthora infestans)
- common water flea (Daphnia pulex)
- corn (Zea mays)
- E. coli (Escherichia coli)
- filamentous fungi (Aspergillus nidulans)
- Firmicute bacteria (Streptococcus pneumoniae)
- fission yeast (Schizosaccharomyces pombe)
- fruit fly (Drosophila melanogaster)
- green algae (Chlamydomonas reinhardtii)
- honey bee (Apis mellifera)
- K. lactis yeast (Kluyveromyces lactis)
- loblloly pine (Pinus taeda)
- malaria parasite (Plasmodium falciparum)
- medicago trunc (Medicago Truncatula)
- moss (Physcomitrella patens)
- orangutan (Pongo pygmaeus)
- pig (Sus scrofa)
- rainbow trout (Oncorhynchus mykiss)
- rice (Oryza sativa)
- rice blast fungus (Magnaporthe grisea)
- schistosome parasite (Schistosoma mansoni)
- sea anemone (Nematostella vectensis)
- sea squirt (Ciona intestinalis)
- sea squirt (Ciona savignyi)
- sea urchin (Strongylocentrotus purpuratus)
- sorghum (Sorghum bicolor)
- soybean (Glycine max)
- stem rust fungus (Puccinia graminis)
- sugarcane (Saccharum officinarum)
- thale cress (Arabidopsis thaliana)
- tomato (Lycopersicon esculentum)
- toxoplasmosis (Toxoplasma gondii)
- Trichoplax (Trichoplax adhaerens)
- wheat (Triticum aestivum)
- worm (Caenorhabditis elegans)
Paralogs for TMTC1 Gene
(3) SIMAP similar genes for TMTC1 Gene using alignment to 4 proteins:
Pseudogenes.org Pseudogenes for TMTC1 Gene
Variants for TMTC1 Gene
| SNP ID | Clin | Chr 12 pos | Variation | AA Info | Type |
|---|---|---|---|---|---|
| rs1000020101 | -- | 29,768,413(-) | C/T | genic_upstream_transcript_variant, intron_variant | |
| rs1000020839 | -- | 29,720,840(-) | T/C | genic_upstream_transcript_variant, intron_variant | |
| rs1000029919 | -- | 29,768,133(-) | C/A | genic_upstream_transcript_variant, intron_variant | |
| rs1000030110 | -- | 29,500,861(-) | T/C | 3_prime_UTR_variant, genic_downstream_transcript_variant | |
| rs1000034584 | -- | 29,726,865(-) | C/T | genic_upstream_transcript_variant, intron_variant |
Residual Variation Intolerance Score:
53.7% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score:
7.07;
80.35% of all genes are more intolerant (likely to be disease-causing)
Additional Variant Information for TMTC1 Gene
- SNPedia medical, phenotypic, and genealogical associations of SNPs for
- TMTC1
No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for TMTC1 Gene
Disorders for TMTC1 Gene
| Disorder | Aliases | PubMed IDs |
|---|---|---|
| spinal cord disease |
|
|
| brown-sequard syndrome |
|
|
| femoral neuropathy |
|
|
Search TMTC1 in MalaCards
View complete list of genes associated with diseases
Additional Disease Information for TMTC1
- Genetic Association Database
- (GAD)
- Human Genome Epidemiology Navigator
- (HuGE)
- ATLAS of Genetics and Cytogenetics in Oncology and Haematology
No data available for UniProtKB/Swiss-Prot and Genatlas for TMTC1 Gene
Publications for TMTC1 Gene
- TMTC1 and TMTC2 are novel endoplasmic reticulum tetratricopeptide repeat-containing adapter proteins involved in calcium homeostasis. (PMID: 24764305) Sunryd JC … Hebert DN (The Journal of biological chemistry 2014) 2 3 58
- Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. (PMID: 20379614) Rose JE … Uhl GR (Molecular medicine (Cambridge, Mass.) 2010) 3 44 58
- Variation at the NFATC2 locus increases the risk of thiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) study. (PMID: 20628086) Bailey SD … DREAM investigators (Diabetes care 2010) 3 44 58
- Genetic variants in nuclear-encoded mitochondrial genes influence AIDS progression. (PMID: 20877624) Hendrickson SL … O'Brien SJ (PloS one 2010) 3 44 58
- Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T … Sugano S (Nature genetics 2004) 3 4 58
Products for TMTC1 Gene
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- Browse R&D Systems for biochemical assays
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- Browse Primary Antibodies
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- Browse Cell Selection and Detection Kits
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- Browse ELISpot/FluoroSpot Kits and Development Modules
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- Browse Proteome Profiler Antibody Arrays
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- Custom Antibody Services
- Browse OriGene ELISA Kits
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- OriGene Purified Proteins for TMTC1
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- Origene Custom Protein Services for TMTC1
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- Browse OriGene Inhibitory RNA Products For TMTC1
- OriGene qPCR primer pairs and template standards for TMTC1
- OriGene qPCR primer pairs for TMTC1
- OriGene CRISPR knockouts for TMTC1
- OriGene ORF clones in human for TMTC1
- Custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
- Browse OriGene miRNA Products For TMTC1
- GenScript: Next-day shipping of latest version cDNA ORF clones for TMTC1 in any vector
- GenScript Custom Purified and Recombinant Proteins Services for TMTC1
- GenScript Custom Assay Services for TMTC1
- GenScript Custom overexpressing Cell Line Services for TMTC1
- GenScript: Design CRISPR guide RNA sequences for TMTC1
- Design optimal peptide antigens
- CloneReady with Over 120,000 Genes
- Gene Synthesis: Any Gene in Any Vector
- Vector-based siRNA and miRNA, Ready for Transfection
- Gene Mutant Library, Variants up to 10^11
- Plasmid Preparation
- GenScript Custom Peptide Services for TMTC1
- Browse Sino Biological cDNA Clones
- Browse Sino Biological Cell Lysates
- Browse Sino Biological Recombinant Proteins
- Browse Sino Biological Antibodies
- Browse Sino Biological Assays
- Browse Sino Biological ELISA Kits
- Browse Sino Biological ELISA Pair Sets
- Browse Sino Biological CRO Services
- Browse Sino Biological Control Vectors
- Sino Biological Transfection Reagent
- Sino Biological Anti-His Tag Antibody
- Novus Biologicals Antibodies for TMTC1
- Novus Biologicals lysates and proteins for TMTC1
- Novus Biologicals
- Novus Biologicals Tissue Microarrays
- Browse Antibodies
- Browse Peptides and Proteins
- Browse Lysates
- Browse ELISA Kits
- Abcam proteins for TMTC1
- Find your target
- Browse Primary Antibodies
- Browse Conjugated Primary Antibodies
- Browse Secondary Antibodies
- Browse ELISA Kits
- Browse Matched Antibody Pairs
- Browse Proteins and Peptides
- Search Knockout (KO) Validated Antibodies
- Browse Monoclonal Antibodies
- Browse Recombinant Antibodies
- Browse Antibodies at Cloud-Clone Corp.
- Browse Proteins at Cloud-Clone Corp.
- Browse Assay Kits at Cloud-Clone Corp.
- Browse Knockouts at Cloud-Clone Corp.
- Browse Knockins at Cloud-Clone Corp.
- Cloud-Clone Corp. disease models service
- Browse cDNA clones at Cloud-Clone Corp.
- Browse primers at Cloud-Clone Corp.
- Cloud-Clone Corp. primary cells service
- Invitrogen Antibodies for TMTC1
- Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat
- Cyagen custom Knockout/knockin (KOKI) mouse models for TMTC1
- VectorBuilder custom plasmid, inducible vectors for TMTC1
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for TMTC1
- VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
- antibodies-online: Search results for available TMTC1 related products ranked by validation data
- antibodies-online: Search results for available TMTC1 related products ranked by validation data
- antibodies-online: Search results for available TMTC1 related products ranked by validation data
- GeneTex TMTC1 antibody for TMTC1
- Search GeneTex for Proteins for TMTC1
- ViGene Biosciences adenoviral particle packaged cDNA for TMTC1 gene
- ViGene Biosciences lentiviral particle packaged cDNA for TMTC1 gene
- ViGene Biosciences ready-to-package AAV shRNAs for TMTC1 gene
- Search ViGene Biosciences for TMTC1
- Horizon Cell Lines for TMTC1
- genomics-online: cdna clones - Search results for available TMTC1 gene related products
- orf clones - Search results for available TMTC1 gene related products
- genomics-online: gRNA clones - Search results for available TMTC1 gene related products
- genomics-online: primer clones - Search results for available TMTC1 gene related products
- genomics-online: shRNA clones - Search results for available TMTC1 gene related products
Sources for TMTC1 Gene
- (1) GeneCards
- (2) HGNC
- (3) EntrezGene
- (4) Swiss-Prot
- (5) Ensembl
- (6) OMIM
- (7) GeneLoc
- (8) Gene Wiki
- (9) UCSC
- (10) PhosphoSitePlus
- (11) GO
- (12) TrEMBL
- (13) InterPro
- (14) ProtoNet
- (15) Blocks
- (16) MGI
- (17) IUBMB
- (18) KEGG
- (19) MINT
- (20) STRING
- (21) IntAct
- (22) Novoseek
- (23) PharmGKB
- (24) DrugBank
- (25) HMDB
- (26) UniGene
- (27) AceView
- (28) ASD
- (29) ECgene
- (30) GeneAnnot
- (31) CGAP SAGE
- (32) SOURCE
- (33) HomoloGene
- (34) PanEnsembl
- (35) euGenes
- (36) SGD
- (37) FlyBase
- (38) WormBase
- (39) Pseudogene
- (40) DGV
- (41) dbSNP
- (42) GenAtlas
- (43) HGMD
- (44) GAD
- (45) BGMUT
- (46) HuGE
- (47) Atlas
- (48) Cell Signaling Technology
- (49) GenBank
- (50) H-invDB
- (51) HORDE
- (52) HUGE
- (53) IMGT
- (54) Leiden
- (55) miRBase
- (56) DME
- (57) OriGene
- (58) PubMed
- (59) R&D Systems
- (60) TGDB
- (61) Tocris
- (62) Abcam
- (63) Novus Biologicals
- (64) ProSpec
- (65) Sino Biological
- (66) GenScript
- (67) Qiagen
- (68) Cloud-Clone Corp.
- (69) OCA
- (70) Proteopedia
- (71) MOPED
- (72) neXtProt
- (73) Reactome
- (74) GeneGo (Thomson Reuters)
- (75) fRNAdb
- (76) DISEASES
- (77) SIMAP
- (78) GenomeRNAi
- (79) LifeMap
- (80) miRTarBase
- (81) MalaCards
- (82) Invitrogen
- (83) BitterDB
- (84) Vector BioLabs
- (85) ESI-BIO
- (86) RefSeq
- (87) BioSystems
- (88) MaxQB
- (89) IUPHAR
- (90) BioGPS
- (91) Illumina
- (92) COMPARTMENTS
- (93) HOMER
- (94) PaxDb
- (95) ApexBio
- (96) Addgene
- (97) antibodies-online
- (98) CYP
- (99) NONCODE
- (100) SwitchGear Genomics
- (101) TreeFam
- (102) PathCards
- (103) GeneReviews
- (104) GeneTex
- (105) Taconic Biosciences
- (106) GTEx
- (107) ProteomicsDB
- (108) SCBT
- (109) DGIdb
- (110) ClinicalTrials
- (111) FDA Approved Drugs
- (112) RVIS
- (113) SIGNOR
- (114) diseasecard
- (115) NIH Rare Diseases
- (116) Orphanet
- (117) UMLS
- (118) GTR
- (119) Disease Ontology
- (120) Genetics Home Reference
- (121) MeSH
- (122) MedlinePlus
- (123) CDC
- (124) NINDS
- (125) NCBI Bookshelf
- (126) ClinVar
- (127) Gene Damage Index
- (128) ViGene Biosciences
- (129) HPO
- (130) UDN
- (131) VISTA
- (132) FANTOM5
- (133) ENCODE
- (134) ProSci
- (135) Horizon
- (136) NURSA
- (137) IID
- (138) Cyagen
- (139) VectorBuilder
- (140) SNPedia
- (141) BRCA Exchange
- (142) St John's Lab
- (143) CIViC
- (144) ProteoGenix
- (145) dbSUPER
- (146) TISSUES
- (147) Gene ORGANizer
- (148) abm
- (149) CrownBio
- (150) Human Protein Atlas
- (151) GWAS Catalog
- (152) Monarch Initiative
- (153) DataMed
- (154) HumanCyc
- (155) genomics-online
- (156) UCNEbase
- (157) EPDnew