Aliases for TMPO-AS1 Gene

Subcategory (RNA class) for TMPO-AS1 Gene

lncRNA

Number of RNA Genes sources:

3 / 17

Aliases for TMPO-AS1 Gene

  • TMPO Antisense RNA 1 2 3 5
  • TMPO-AS1 2 5 165
  • TMPO Antisense RNA 1 (Non-Protein Coding) 2 3
  • NONHSAG012025.2 91
  • HSALNG0093383 164

External Ids for TMPO-AS1 Gene

Previous GeneCards Identifiers for TMPO-AS1 Gene

  • GC12M098909

Summaries for TMPO-AS1 Gene

GeneCards Summary for TMPO-AS1 Gene

TMPO-AS1 (TMPO Antisense RNA 1) is an RNA Gene, and is affiliated with the lncRNA class. Diseases associated with TMPO-AS1 include Loeys-Dietz Syndrome 2 and Loeys-Dietz Syndrome.

Additional gene information for TMPO-AS1 Gene

No data available for Entrez Gene Summary , CIViC Summary , UniProtKB/Swiss-Prot Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , Rfam classification and piRNA Summary for TMPO-AS1 Gene

Genomics for TMPO-AS1 Gene

GeneHancer (GH) Regulatory Elements Pubs

Promoters and enhancers for TMPO-AS1 Gene
GeneHancer (GH) Identifier GH Type GH
Score
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH12J098512 Promoter/Enhancer 2.4 EPDnew Ensembl ENCODE CraniofacialAtlas dbSUPER 605.9 -0.1 -61 7.8 SP1 HNRNPL CREB1 GATAD2A CTCF PRDM10 ZNF629 TFE3 SIX5 LEF1 TMPO TMPO-AS1 RNU4-41P SLC9A7P1 LINC02453 lnc-IKBIP-7 SLC25A3
GH12J098509 Enhancer 1 Ensembl ENCODE 5.6 +7.1 7138 1 LEF1 IKZF1 JUND PHF21A MTA1 DPF2 HDAC1 SOX6 GATAD2B TCF12 TMPO TMPO-AS1 lnc-IKBIP-6
GH12J098520 Enhancer 0.6 dbSUPER 0.7 -5.0 -4997 1 PRDM10 ZNF600 SCRT2 ZNF524 OSR2 ZNF335 ZBTB1 KLF17 PRDM6 GLIS1 RNU4-41P TMPO TMPO-AS1 lnc-IKBIP-7 SLC25A3
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data from 2017 publication | Request up-to-date GeneHancer data (full dataset)

GeneHancers around TMPO-AS1 on the GeneHancer Hub at the UCSC Golden Path

Genomic Locations for TMPO-AS1 Gene

Genomic Locations for TMPO-AS1 Gene
chr12:98,510,418-98,516,454
(GRCh38/hg38)
Size:
6,037 bases
Orientation:
Minus strand
chr12:98,906,751-98,910,200
(GRCh37/hg19)
Size:
3,450 bases
Orientation:
Minus strand

Genomic View for TMPO-AS1 Gene

Genes around TMPO-AS1 on UCSC Golden Path with GeneCards custom track
TMPO-AS1 in the GeneCards ncRNA compendium hub on the UCSC Golden Path

Cytogenetic band:
TMPO-AS1 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for TMPO-AS1 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for TMPO-AS1 Gene

Proteins for TMPO-AS1 Gene

Post-translational modifications for TMPO-AS1 Gene

No Post-translational modifications

No data available for DME Specific Peptides for TMPO-AS1 Gene

Domains & Families for TMPO-AS1 Gene

Gene Families for TMPO-AS1 Gene

genes like me logo Genes that share domains with TMPO-AS1: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences , Graphical View of Domain Structure and UniProtKB/Swiss-Prot for TMPO-AS1 Gene

Function for TMPO-AS1 Gene

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes From GWAS Catalog , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for TMPO-AS1 Gene

Localization for TMPO-AS1 Gene

Subcellular locations from

COMPARTMENTS
Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for TMPO-AS1 gene
Compartment Confidence
nucleus 1

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for TMPO-AS1 Gene

Pathways & Interactions for TMPO-AS1 Gene

PathCards logo

SuperPathways for TMPO-AS1 Gene

No Data Available

Gene Ontology (GO) - Biological Process for TMPO-AS1 Gene

None

No data available for Pathways by source , Interacting Proteins and SIGNOR curated interactions for TMPO-AS1 Gene

Drugs & Compounds for TMPO-AS1 Gene

No Compound Related Data Available

Transcripts for TMPO-AS1 Gene

Non-coding RNA (ncRNA) Transcripts from RNAcentral for TMPO-AS1 Gene

RNAcentral Transcript ID Subcategory Length (nts) # of Sources Source Identifiers and Annotations
URS000025C0C6_9606 lncRNA 3357 4

Ensembl: ENST00000548760 (view in UCSC) ,

LncBook: HSALNT0193783,

LNCipedia: TMPO-AS1:1,

NONCODE: NONHSAT030138.2,

URS000075B992_9606 lncRNA 3161 4

HGNC: 44158,

RefSeq: NR_027157,

LncBook: HSALNT0193785,

LNCipedia: TMPO-AS1:2,

URS00001473AA_9606 lncRNA 738 3

Ensembl: ENST00000546421 (view in UCSC) ,

LNCipedia: TMPO-AS1:3,

NONCODE: NONHSAT030141.2,

URS00008B9634_9606 lncRNA 1180 3

LncBook: HSALNT0193786,

LNCipedia: TMPO-AS1:4,

NONCODE: NONHSAT030139.2,

URS0000D56F39_9606 lncRNA 5951 2

LncBook: HSALNT0193779,

LNCipedia: TMPO-AS1:9,

TMPO-AS1 in the GeneCards ncRNA compendium hub on the UCSC Golden Path

Additional transcripts not in RNAcentral for TMPO-AS1 Gene

4 NCBI additional mRNA sequence :

Alternative Splicing Database (ASD) splice patterns (SP) for TMPO-AS1 Gene

No ASD Table

Relevant External Links for TMPO-AS1 Gene

GeneLoc Exon Structure for
TMPO-AS1

Expression for TMPO-AS1 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and SAGE for TMPO-AS1 Gene

mRNA differential expression in normal tissues according to GTEx for TMPO-AS1 Gene

This gene is overexpressed in Testis (x9.3).

Transcriptomic regulation report from SPP (The Signaling Pathways Project) for TMPO-AS1

SOURCE GeneReport for Unigene cluster for TMPO-AS1 Gene:

Hs.594042
genes like me logo Genes that share expression patterns with TMPO-AS1: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for TMPO-AS1 Gene

Orthologs for TMPO-AS1 Gene

Evolution for TMPO-AS1 Gene

ENSEMBL:
Gene Tree for TMPO-AS1 (if available)
TreeFam:
Gene Tree for TMPO-AS1 (if available)

No data available for Orthologs for TMPO-AS1 Gene

Paralogs for TMPO-AS1 Gene

No data available for Paralogs for TMPO-AS1 Gene

Variants for TMPO-AS1 Gene

Sequence variations, with clinical significance, from ClinVar and Humsavar, with links to dbSNP for TMPO-AS1 Gene

SNP ID Clinical significance and condition Chr 12 pos Variation AA Info Type
659030 Uncertain Significance: Loeys-Dietz syndrome 2 98,515,995(-) A/G MISSENSE_VARIANT,NON_CODING_TRANSCRIPT_VARIANT
684009 Benign: not provided 98,515,429(-) C/T NON_CODING_TRANSCRIPT_VARIANT
695615 Likely Benign: Loeys-Dietz syndrome 2 98,515,880(-) C/T NON_CODING_TRANSCRIPT_VARIANT,SYNONYMOUS_VARIANT
800206 Likely Benign: Loeys-Dietz syndrome 2 98,516,105(-) G/A MISSENSE_VARIANT,NON_CODING_TRANSCRIPT_VARIANT
842091 Uncertain Significance: Loeys-Dietz syndrome 2 98,516,031(-) C/T MISSENSE_VARIANT,NON_CODING_TRANSCRIPT_VARIANT

Additional dbSNP identifiers (rs#s) for TMPO-AS1 Gene

Structural Variations from Database of Genomic Variants (DGV) for TMPO-AS1 Gene

Variant ID Type Subtype PubMed ID
nsv7234 OTHER inversion 18451855

Additional Variant Information for TMPO-AS1 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
TMPO-AS1

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for TMPO-AS1 Gene

Disorders for TMPO-AS1 Gene

MalaCards: The human disease database

(2) MalaCards diseases for TMPO-AS1 Gene - From: GeneCards

Disorder Aliases PubMed IDs
loeys-dietz syndrome 2
  • lds2
loeys-dietz syndrome
  • furlong syndrome
- elite association - COSMIC cancer census association via MalaCards
genes like me logo Genes that share disorders with TMPO-AS1: view

No data available for UniProtKB/Swiss-Prot and Genatlas for TMPO-AS1 Gene

Publications for TMPO-AS1 Gene

  1. Long noncoding RNA TMPO-AS1 promotes progression of non-small cell lung cancer through regulating its natural antisense transcript TMPO. (PMID: 31230752) Qin Z … Fang Y (Biochemical and biophysical research communications 2019) 2 3
  2. ESR1-Stabilizing Long Noncoding RNA TMPO-AS1 Promotes Hormone-Refractory Breast Cancer Progression. (PMID: 31501276) Mitobe Y … Inoue S (Molecular and cellular biology 2019) 3
  3. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T … Sugano S (Nature genetics 2004) 3
  4. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg RL … Mammalian Gene Collection Program Team (Proceedings of the National Academy of Sciences of the United States of America 2002) 3

Products for TMPO-AS1 Gene

Sources for TMPO-AS1 Gene