Aliases for TMIGD3 Gene
This gene encodes a transmembrane and immunoglobulin domain-containing protein. Alternative splicing results in multiple transcript variants, one of which shares its 5' terminal exon with that of the overlapping adenosine A3 receptor gene (GeneID:140), thus resulting in a fusion product. [provided by RefSeq, Nov 2014]
GeneCards Summary for TMIGD3 Gene
TMIGD3 (Transmembrane And Immunoglobulin Domain Containing 3) is a Protein Coding gene. Gene Ontology (GO) annotations related to this gene include G protein-coupled receptor activity and G protein-coupled adenosine receptor activity. An important paralog of this gene is CD300E.
UniProtKB/Swiss-Prot Summary for TMIGD3 Gene
Isoform 1: Plays a suppressive role in osteosarcoma malignancy by inhibiting NF-kappa-B activity (PubMed:27886186).