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TMIGD2 (Transmembrane And Immunoglobulin Domain Containing 2) is a Protein Coding gene. Gene Ontology (GO) annotations related to this gene include coreceptor activity.
GO ID | Qualified GO term | Evidence | PubMed IDs |
---|---|---|---|
GO:0005515 | protein binding | IPI | 23784006 |
GO:0015026 | coreceptor activity | IDA | 23784006 |
GO ID | Qualified GO term | Evidence | PubMed IDs |
---|---|---|---|
GO:0005615 | extracellular space | IBA | 21873635 |
GO:0005886 | plasma membrane | IEA | -- |
GO:0016020 | membrane | IEA | -- |
GO:0016021 | integral component of membrane | IEA | -- |
GO ID | Qualified GO term | Evidence | PubMed IDs |
---|---|---|---|
GO:0001819 | positive regulation of cytokine production | IDA | 23784006 |
GO:0002377 | immunoglobulin production | IBA | 21873635 |
GO:0006955 | immune response | IBA | 21873635 |
GO:0031295 | T cell costimulation | IDA | 23784006 |
GO:0042104 | positive regulation of activated T cell proliferation | IDA | 23784006 |
ExUns: | 1 | ^ | 2 | ^ | 3 | ^ | 4a | · | 4b | ^ | 5 |
---|---|---|---|---|---|---|---|---|---|---|---|
SP1: | |||||||||||
SP2: | - |
This gene was present in the common ancestor of mammals.
Organism | Taxonomy | Gene | Similarity | Type | Details |
---|---|---|---|---|---|
Chimpanzee (Pan troglodytes) |
Mammalia | TMIGD2 30 31 |
|
OneToOne | |
Cow (Bos Taurus) |
Mammalia | TMIGD2 30 31 |
|
OneToOne | |
Oppossum (Monodelphis domestica) |
Mammalia | TMIGD2 31 |
|
OneToOne |
SNP ID | Clinical significance and condition | Chr 19 pos | Variation | AA Info | Type |
---|---|---|---|---|---|
731137 | Benign: not provided | 4,298,201(-) | G/A | MISSENSE_VARIANT,INTRON_VARIANT | |
731138 | Benign: not provided | 4,298,244(-) | T/G | MISSENSE_VARIANT,INTRON_VARIANT | |
731139 | Benign: not provided | 4,298,248(-) | C/T | SYNONYMOUS_VARIANT,INTRON_VARIANT | |
773771 | Benign: not provided | 4,298,067(-) | C/T | MISSENSE_VARIANT,INTRON_VARIANT | |
781731 | Benign: not provided | 4,302,374(-) | C/T | SYNONYMOUS_VARIANT |
Variant ID | Type | Subtype | PubMed ID |
---|---|---|---|
esv2677475 | CNV | deletion | 23128226 |
esv2718004 | CNV | deletion | 23290073 |
esv3643495 | CNV | loss | 21293372 |
esv3643497 | CNV | gain | 21293372 |
nsv1109161 | CNV | deletion | 24896259 |
nsv578442 | CNV | loss | 21841781 |
nsv833717 | CNV | loss | 17160897 |
nsv833718 | CNV | loss | 17160897 |
No disorders were found for TMIGD2 Gene.