Aliases for TMEM30B Gene
External Ids for TMEM30B Gene
Previous GeneCards Identifiers for TMEM30B Gene
GeneCards Summary for TMEM30B Gene
TMEM30B (Transmembrane Protein 30B) is a Protein Coding gene. Diseases associated with TMEM30B include Sphenoorbital Meningioma and Cholestasis, Benign Recurrent Intrahepatic, 1. An important paralog of this gene is TMEM30A.
UniProtKB/Swiss-Prot Summary for TMEM30B Gene
Accessory component of a P4-ATPase flippase complex which catalyzes the hydrolysis of ATP coupled to the transport of aminophospholipids from the outer to the inner leaflet of various membranes and ensures the maintenance of asymmetric distribution of phospholipids. Phospholipid translocation seems also to be implicated in vesicle formation and in uptake of lipid signaling molecules. The beta subunit may assist in binding of the phospholipid substrate (Probable). Can mediate the export of alpha subunits ATP8A1, ATP8B1, ATP8B2 and ATP8B4 from the ER to the plasma membrane.