Aliases for TMEM269 Gene

Aliases for TMEM269 Gene

  • Transmembrane Protein 269 2 3 4 5

External Ids for TMEM269 Gene

Summaries for TMEM269 Gene

GeneCards Summary for TMEM269 Gene

TMEM269 (Transmembrane Protein 269) is a Protein Coding gene. An important paralog of this gene is CDIPT.

Additional gene information for TMEM269 Gene

No data available for Entrez Gene Summary , CIViC Summary , UniProtKB/Swiss-Prot Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , Rfam classification and piRNA Summary for TMEM269 Gene

Genomics for TMEM269 Gene

GeneHancer (GH) Regulatory Elements for TMEM269 Gene

Promoters and enhancers for TMEM269 Gene
GeneHancer (GH) Identifier GH Type GH
Score
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH01J042784 Promoter/Enhancer 0.9 FANTOM5 Ensembl 500.7 +0.2 194 1.2 PRPF4 POLR2G ZBTB33 PCBP1 AGO2 AGO1 PKNOX1 RBFOX2 TMEM269 TMEM269-DT SVBP ZMYND12 CFAP57 YBX1 lnc-SVBP-4 ENSG00000283580
GH01J042815 Promoter/Enhancer 2 EPDnew Ensembl ENCODE CraniofacialAtlas 0.3 +32.0 31994 2.8 EP300 SIN3A NRF1 POLR2G SP1 PHF8 ZNF10 ZIC2 POLR2A ZBTB26 SVBP ERMAP lnc-SVBP-2 PPIH ZNF691 ENSG00000228192 P3H1 SLC2A1-AS1 piR-37097-002 TMEM269
GH01J042806 Enhancer 0.6 Ensembl ENCODE 0.4 +22.4 22431 1.3 POLR2A SMARCA4 EZH2 P3H1 ENSG00000228192 ZNF691 YBX1 SVBP piR-37097-002 ERMAP TMEM269
GH01J042813 Enhancer 0.5 Ensembl 0.3 +28.8 28794 0.4 TEAD1 ZNF316 TRIM24 NFE2 TEAD3 ZNF384 ERMAP SVBP lnc-SVBP-2 piR-37097-002 TMEM269
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data from 2017 publication | Request up-to-date GeneHancer data (full dataset)

GeneHancers around TMEM269 on UCSC Golden Path with GeneCards custom track

Cistromic (ChIP-Seq) regulation report from SPP (The Signaling Pathways Project) for TMEM269

Genomic Locations for TMEM269 Gene

Genomic Locations for TMEM269 Gene
chr1:42,785,007-42,816,619
(GRCh38/hg38)
Size:
31,613 bases
Orientation:
Plus strand
chr1:43,253,661-43,263,901
(GRCh37/hg19)
Size:
10,241 bases
Orientation:
Plus strand

Genomic View for TMEM269 Gene

Genes around TMEM269 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
TMEM269 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for TMEM269 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for TMEM269 Gene

Proteins for TMEM269 Gene

  • Protein details for TMEM269 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    A0A1B0GVZ9-TM269_HUMAN
    Recommended name:
    Transmembrane protein 269
    Protein Accession:
    A0A1B0GVZ9

    Protein attributes for TMEM269 Gene

    Size:
    245 amino acids
    Molecular mass:
    26874 Da
    Quaternary structure:
    No Data Available

neXtProt entry for TMEM269 Gene

Post-translational modifications for TMEM269 Gene

No Post-translational modifications

Other Protein References for TMEM269 Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for TMEM269 Gene

Domains & Families for TMEM269 Gene

Gene Families for TMEM269 Gene

Human Protein Atlas (HPA):
  • Predicted membrane proteins

Protein Domains for TMEM269 Gene

ProtoNet:
genes like me logo Genes that share domains with TMEM269: view

No data available for Suggested Antigen Peptide Sequences , Graphical View of Domain Structure and UniProtKB/Swiss-Prot for TMEM269 Gene

Function for TMEM269 Gene

Inhibitory RNA Products

  • Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for TMEM269

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes From GWAS Catalog , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for TMEM269 Gene

Localization for TMEM269 Gene

Subcellular locations from UniProtKB/Swiss-Prot for TMEM269 Gene

Membrane; Multi-pass membrane protein.

Gene Ontology (GO) - Cellular Components for TMEM269 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0016021 integral component of membrane IEA --
genes like me logo Genes that share ontologies with TMEM269: view

No data available for Subcellular locations from COMPARTMENTS and Subcellular locations from the Human Protein Atlas (HPA) for TMEM269 Gene

Pathways & Interactions for TMEM269 Gene

PathCards logo

SuperPathways for TMEM269 Gene

No Data Available

Interacting Proteins for TMEM269 Gene

;

Gene Ontology (GO) - Biological Process for TMEM269 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for TMEM269 Gene

Drugs & Compounds for TMEM269 Gene

No Compound Related Data Available

Transcripts for TMEM269 Gene

mRNA/cDNA for TMEM269 Gene

2 REFSEQ mRNAs :
2 NCBI additional mRNA sequence :
4 Ensembl transcripts including schematic representations, and UCSC links to gene/alias where relevant :

Inhibitory RNA Products

  • Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for TMEM269

Alternative Splicing Database (ASD) splice patterns (SP) for TMEM269 Gene

No ASD Table

Relevant External Links for TMEM269 Gene

GeneLoc Exon Structure for
TMEM269

Expression for TMEM269 Gene

Transcriptomic regulation report from SPP (The Signaling Pathways Project) for TMEM269

No Expression Related Data Available

Primer Products

No data available for mRNA expression in normal human tissues , mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for TMEM269 Gene

Orthologs for TMEM269 Gene

This gene was present in the common ancestor of chordates.

Orthologs for TMEM269 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia LOC748966 30
  • 99.05 (n)
dog
(Canis familiaris)
Mammalia LOC482440 30
  • 83.63 (n)
cow
(Bos Taurus)
Mammalia LOC531467 30
  • 81.4 (n)
rat
(Rattus norvegicus)
Mammalia RGD1563015 30
  • 78.61 (n)
mouse
(Mus musculus)
Mammalia 4930538K18Rik 30
  • 78.29 (n)
Tmem269 17
chicken
(Gallus gallus)
Aves LOC100859906 30
  • 62.6 (n)
zebrafish
(Danio rerio)
Actinopterygii si:dkey-205h13.1 30
  • 58.87 (n)
Species where no ortholog for TMEM269 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for TMEM269 Gene

ENSEMBL:
Gene Tree for TMEM269 (if available)
TreeFam:
Gene Tree for TMEM269 (if available)

Paralogs for TMEM269 Gene

Paralogs for TMEM269 Gene

genes like me logo Genes that share paralogs with TMEM269: view

Variants for TMEM269 Gene

Additional dbSNP identifiers (rs#s) for TMEM269 Gene

Structural Variations from Database of Genomic Variants (DGV) for TMEM269 Gene

Variant ID Type Subtype PubMed ID
esv3577249 CNV gain 25503493

Additional Variant Information for TMEM269 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
TMEM269

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Sequence variations, with clinical significance, from ClinVar and Humsavar, with links to dbSNP and Variation tolerance for TMEM269 Gene

Disorders for TMEM269 Gene

Additional Disease Information for TMEM269

No disorders were found for TMEM269 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for TMEM269 Gene

Publications for TMEM269 Gene

  1. The DNA sequence and biological annotation of human chromosome 1. (PMID: 16710414) Gregory SG … Prigmore E (Nature 2006) 4 54

Products for TMEM269 Gene

Sources for TMEM269 Gene