Aliases for TMEM265 Gene

Aliases for TMEM265 Gene

  • Transmembrane Protein 265 2 3 4 5
  • IFITMD8 3
  • TMEM265 5

External Ids for TMEM265 Gene

Previous GeneCards Identifiers for TMEM265 Gene

  • GC16P030699

Summaries for TMEM265 Gene

GeneCards Summary for TMEM265 Gene

TMEM265 (Transmembrane Protein 265) is a Protein Coding gene. Gene Ontology (GO) annotations related to this gene include transcription coactivator activity and histone acetyltransferase activity.

Additional gene information for TMEM265 Gene

No data available for Entrez Gene Summary , CIViC Summary , UniProtKB/Swiss-Prot Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , Rfam classification and piRNA Summary for TMEM265 Gene

Genomics for TMEM265 Gene

GeneHancer (GH) Regulatory Elements Pubs

Promoters and enhancers for TMEM265 Gene
GeneHancer (GH) Identifier GH Type GH
Score
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH16J030739 Promoter/Enhancer 1.7 EPDnew Ensembl ENCODE dbSUPER 600.7 +0.4 426 3.3 CEBPG ATF7 PRDM10 ZNF629 RFX1 ZNF692 POLR2A PRDM1 PATZ1 REST ENSG00000260899 TMEM265 SNORA30 SRCAP PHKG2 ENSG00000282034
GH16J030746 Promoter 0.3 EPDnew 600.7 +3.2 3150 0.1 TMEM265 SNORA30 SRCAP ENSG00000260899 PHKG2 ENSG00000282034
GH16J030745 Enhancer 0.7 ENCODE 0.7 +4.7 4653 0.2 RCOR2 RXRB SP1 FOXA2 SMARCC2 YY1 CREB1 GABPA JUND CREM SNORA30 SRCAP ENSG00000260899 PHKG2 TMEM265
GH16J030748 Enhancer 0.7 Ensembl 0.7 +4.5 4459 0.2 RCOR2 RXRB SP1 FOXA2 SMARCC2 YY1 CREB1 GABPA JUND CREM SNORA30 SRCAP ENSG00000260899 PHKG2 TMEM265 ENSG00000282034
GH16J030713 Enhancer 1.1 FANTOM5 Ensembl ENCODE 0.3 -25.3 -25341 5.8 PRDM10 ZNF629 PRDM1 RBFOX2 ZNF600 PKNOX1 SCRT2 CEBPB NFE2 JUN CCDC189 RNF40 STX4 ZNF764 GDPD3 ZNF646 KAT8 FUS ZNF668 SNORA30
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data from 2017 publication | Request up-to-date GeneHancer data (full dataset)

GeneHancers around TMEM265 on the GeneHancer Hub at the UCSC Golden Path

Cistromic (ChIP-Seq) regulation report from SPP (The Signaling Pathways Project) for TMEM265

Genomic Locations for TMEM265 Gene

Genomic Locations for TMEM265 Gene
chr16:30,740,642-30,745,196
(GRCh38/hg38)
Size:
4,555 bases
Orientation:
Plus strand

Genomic View for TMEM265 Gene

Genes around TMEM265 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
TMEM265 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for TMEM265 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for TMEM265 Gene

Proteins for TMEM265 Gene

  • Protein details for TMEM265 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    A0A087WTH1-TM265_HUMAN
    Recommended name:
    Transmembrane protein 265
    Protein Accession:
    A0A087WTH1

    Protein attributes for TMEM265 Gene

    Size:
    108 amino acids
    Molecular mass:
    11832 Da
    Quaternary structure:
    No Data Available

neXtProt entry for TMEM265 Gene

Post-translational modifications for TMEM265 Gene

No Post-translational modifications

Other Protein References for TMEM265 Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for TMEM265 Gene

Domains & Families for TMEM265 Gene

Gene Families for TMEM265 Gene

Human Protein Atlas (HPA):
  • Predicted membrane proteins

Protein Domains for TMEM265 Gene

InterPro:
ProtoNet:

Graphical View of Domain Structure for InterPro Entry

A0A087WTH1

UniProtKB/Swiss-Prot:

TM265_HUMAN :
  • Belongs to the CD225/Dispanin family.
Family:
  • Belongs to the CD225/Dispanin family.
genes like me logo Genes that share domains with TMEM265: view

No data available for Suggested Antigen Peptide Sequences for TMEM265 Gene

Function for TMEM265 Gene

Phenotypes From GWAS Catalog for TMEM265 Gene

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for TMEM265 Gene

Localization for TMEM265 Gene

Subcellular locations from UniProtKB/Swiss-Prot for TMEM265 Gene

Membrane. Multi-pass membrane protein.

Gene Ontology (GO) - Cellular Components for TMEM265 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0016020 membrane IEA --
GO:0016021 integral component of membrane IEA --
genes like me logo Genes that share ontologies with TMEM265: view

No data available for Subcellular locations from COMPARTMENTS and Subcellular locations from the Human Protein Atlas (HPA) for TMEM265 Gene

Pathways & Interactions for TMEM265 Gene

PathCards logo

SuperPathways for TMEM265 Gene

No Data Available

Interacting Proteins for TMEM265 Gene

Gene Ontology (GO) - Biological Process for TMEM265 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for TMEM265 Gene

Drugs & Compounds for TMEM265 Gene

No Compound Related Data Available

Transcripts for TMEM265 Gene

mRNA/cDNA for TMEM265 Gene

1 REFSEQ mRNAs :
4 NCBI additional mRNA sequence :
1 Ensembl transcripts including schematic representations, and UCSC links to gene/alias where relevant :

Inhibitory RNA Products

  • Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for TMEM265

Alternative Splicing Database (ASD) splice patterns (SP) for TMEM265 Gene

ExUns: 1 ^ 2a · 2b ^ 3 ^ 4a · 4b ^ 5a · 5b · 5c ^ 6a · 6b ^ 7 ^ 8 ^ 9 ^ 10 ^ 11 ^ 12 ^ 13 ^ 14 ^ 15 ^ 16 ^ 17 ^ 18 ^ 19 ^ 20 ^ 21 ^
SP1:
SP2: -
SP3:
SP4:
SP5: -
SP6:

ExUns: 22a · 22b ^ 23 ^ 24 ^ 25 ^ 26 ^ 27 ^ 28a · 28b ^ 29a · 29b ^ 30 ^ 31a · 31b ^ 32 ^ 33 ^ 34
SP1: - -
SP2: - -
SP3:
SP4:
SP5:
SP6:

Relevant External Links for TMEM265 Gene

GeneLoc Exon Structure for
TMEM265

Expression for TMEM265 Gene

No data available for mRNA expression in normal human tissues , mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for TMEM265 Gene

Orthologs for TMEM265 Gene

This gene was present in the common ancestor of mammals.

Orthologs for TMEM265 Gene

Organism Taxonomy Gene Similarity Type Details
Dog
(Canis familiaris)
Mammalia LOC607399 30
  • 92.9 (n)
Cow
(Bos Taurus)
Mammalia LOC511420 30
  • 89.2 (n)
Rat
(Rattus norvegicus)
Mammalia LOC102554586 30
  • 87.96 (n)
Mouse
(Mus musculus)
Mammalia LOC102634352 30
  • 87.35 (n)
Species where no ortholog for TMEM265 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Eremothecium gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • Alpha proteobacteria (Wolbachia pipientis)
  • Amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • Baker's yeast (Saccharomyces cerevisiae)
  • Barley (Hordeum vulgare)
  • Beta proteobacteria (Neisseria meningitidis)
  • Bread mold (Neurospora crassa)
  • Chicken (Gallus gallus)
  • Chimpanzee (Pan troglodytes)
  • Chromalveolata (Phytophthora infestans)
  • Common water flea (Daphnia pulex)
  • Corn (Zea mays)
  • E. coli (Escherichia coli)
  • Filamentous fungi (Aspergillus nidulans)
  • Firmicute Bacteria (Streptococcus pneumoniae)
  • Fission Yeast (Schizosaccharomyces pombe)
  • Fruit Fly (Drosophila melanogaster)
  • Green Algae (Chlamydomonas reinhardtii)
  • Honey Bee (Apis mellifera)
  • K. Lactis Yeast (Kluyveromyces lactis)
  • Lizard (Anolis carolinensis)
  • Loblloly Pine (Pinus taeda)
  • Malaria Parasite (Plasmodium falciparum)
  • Medicago Trunc (Medicago Truncatula)
  • Moss (Physcomitrella patens)
  • Oppossum (Monodelphis domestica)
  • Orangutan (Pongo pygmaeus)
  • Pig (Sus scrofa)
  • Platypus (Ornithorhynchus anatinus)
  • Rainbow Trout (Oncorhynchus mykiss)
  • Rice (Oryza sativa)
  • Rice Blast Fungus (Magnaporthe grisea)
  • Schistosome Parasite (Schistosoma mansoni)
  • Sea Anemone (Nematostella vectensis)
  • Sea Vase (Ciona intestinalis)
  • Sea Squirt (Ciona savignyi)
  • Sea Urchin (Strongylocentrotus purpuratus)
  • Sorghum (Sorghum bicolor)
  • Soybean (Glycine max)
  • Stem Rust Fungus (Puccinia graminis)
  • Sugarcane (Saccharum officinarum)
  • Thale Cress (Arabidopsis thaliana)
  • Tomato (Lycopersicon esculentum)
  • Toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • Tropical Clawed Frog (Silurana tropicalis)
  • Wheat (Triticum aestivum)
  • Worm (Caenorhabditis elegans)
  • Zebrafish (Danio rerio)

Evolution for TMEM265 Gene

ENSEMBL:
Gene Tree for TMEM265 (if available)
TreeFam:
Gene Tree for TMEM265 (if available)
Aminode:
Evolutionary constrained regions (ECRs) for TMEM265: view image

Paralogs for TMEM265 Gene

No data available for Paralogs for TMEM265 Gene

Variants for TMEM265 Gene

Additional dbSNP identifiers (rs#s) for TMEM265 Gene

Structural Variations from Database of Genomic Variants (DGV) for TMEM265 Gene

Variant ID Type Subtype PubMed ID
nsv469724 CNV loss 16826518
nsv833188 CNV loss 17160897

Additional Variant Information for TMEM265 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
TMEM265

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Sequence variations, with clinical significance, from ClinVar and Humsavar, with links to dbSNP and Variation tolerance for TMEM265 Gene

Disorders for TMEM265 Gene

Additional Disease Information for TMEM265

No disorders were found for TMEM265 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for TMEM265 Gene

Publications for TMEM265 Gene

  1. The sequence and analysis of duplication-rich human chromosome 16. (PMID: 15616553) Martin J … Pennacchio LA (Nature 2004) 4
  2. Expressed sequence tag analysis of human RPE/choroid for the NEIBank Project: over 6000 non-redundant transcripts, novel genes and splice variants. (PMID: 12107410) Wistow G … Peterson K (Molecular vision 2002) 3
  3. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg RL … Mammalian Gene Collection Program Team (Proceedings of the National Academy of Sciences of the United States of America 2002) 3
  4. The sequence of the human genome. (PMID: 11181995) Venter JC … Zhu X (Science (New York, N.Y.) 2001) 3
  5. Prediction of the coding sequences of unidentified human genes. VII. The complete sequences of 100 new cDNA clones from brain which can code for large proteins in vitro. (PMID: 9205841) Nagase T … Ohara O (DNA research : an international journal for rapid publication of reports on genes and genomes 1997) 3

Products for TMEM265 Gene

Sources for TMEM265 Gene