Aliases for TMEM262 Gene

Aliases for TMEM262 Gene

  • Transmembrane Protein 262 2 3 4 5
  • TMEM262 5

External Ids for TMEM262 Gene

Previous GeneCards Identifiers for TMEM262 Gene

  • GC11M064854

Summaries for TMEM262 Gene

GeneCards Summary for TMEM262 Gene

TMEM262 (Transmembrane Protein 262) is a Protein Coding gene.

No data available for Entrez Gene Summary , CIViC Summary , UniProtKB/Swiss-Prot Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , Rfam classification and piRNA Summary for TMEM262 Gene

Genomics for TMEM262 Gene

GeneHancer (GH) Regulatory Elements Pubs

Promoters and enhancers for TMEM262 Gene
GeneHancer (GH) Identifier GH Type GH
Score
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH11J065095 Promoter/Enhancer 2.1 EPDnew Ensembl ENCODE CraniofacialAtlas 0.4 -7.3 -7318 2.2 CHD2 TBP ZBTB10 SP1 BCL11A FEZF1 CEBPA SIX5 NR2C1 MNT VPS51 PCNX3 RNASEH2C ZFPL1 SF3B2 KAT5 FAU MEN1 ENSG00000260233 EIF1AD
GH11J065082 Promoter/Enhancer 2 EPDnew Ensembl ENCODE CraniofacialAtlas 0.4 +5.1 5077 3 CHD2 TBP ZBTB10 SP1 MXD4 CEBPA SIX5 NR2C1 MNT SMAD5 CDCA5 HSALNG0084854 ZFPL1 lnc-TMEM262-2 SNX15 ENSG00000260233 SF1 PCNX3 MEN1 KAT5
GH11J065101 Enhancer 1.1 Ensembl ENCODE dbSUPER 0.4 -12.6 -12594 2.5 FEZF1 RXRA ZNF843 FOXA2 ZBTB33 ZNF146 BCL11B CTCF INSM2 ZNF24 MRPL49 SYVN1 FAU PGAM1P8 LOC728975 CAPN1 SPDYC SAC3D1 HSALNG0084855 lnc-ZNHIT2-2
GH11J065103 Enhancer 0.8 Ensembl ENCODE dbSUPER 0.4 -14.6 -14625 0.8 RXRA KLF1 OSR2 ZBTB17 PRDM10 SP1 PGAM1P8 HSALNG0084855 lnc-ZNHIT2-2 TM7SF2 TMEM262 VPS51
GH11J065104 Enhancer 0.8 Ensembl ENCODE dbSUPER 0.4 -16.2 -16235 1.7 FOXA2 ZBTB33 PRDM10 ZSCAN5C JUND lnc-ZNHIT2-2 LOC728975 SYVN1 PRDX5 TM7SF2 HSALNG0084855 TMEM262 VPS51
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data from 2017 publication | Request up-to-date GeneHancer data (full dataset)

GeneHancers around TMEM262 on the GeneHancer Hub at the UCSC Golden Path

Cistromic (ChIP-Seq) regulation report from SPP (The Signaling Pathways Project) for TMEM262

Genomic Locations for TMEM262 Gene

Latest Assembly
chr11:65,084,979-65,089,375
(GRCh38/hg38)
Size:
4,397 bases
Orientation:
Minus strand

Previous Assembly
chr11:64,855,848-64,856,582
(GRCh37/hg19 by Entrez Gene)
Size:
735 bases
Orientation:
Minus strand

chr11:64,852,451-64,856,847
(GRCh37/hg19 by Ensembl)
Size:
4,397 bases
Orientation:
Minus strand

Genomic View for TMEM262 Gene

Genes around TMEM262 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
TMEM262 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for TMEM262 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for TMEM262 Gene

Proteins for TMEM262 Gene

  • Protein details for TMEM262 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    E9PQX1-TM262_HUMAN
    Recommended name:
    Transmembrane protein 262
    Protein Accession:
    E9PQX1

    Protein attributes for TMEM262 Gene

    Size:
    116 amino acids
    Molecular mass:
    13758 Da
    Quaternary structure:
    No Data Available

neXtProt entry for TMEM262 Gene

Post-translational modifications for TMEM262 Gene

No Post-translational modifications

Other Protein References for TMEM262 Gene

No data available for DME Specific Peptides for TMEM262 Gene

Domains & Families for TMEM262 Gene

Gene Families for TMEM262 Gene

Human Protein Atlas (HPA):
  • Predicted membrane proteins

Protein Domains for TMEM262 Gene

InterPro:
ProtoNet:
genes like me logo Genes that share domains with TMEM262: view

No data available for Suggested Antigen Peptide Sequences , Graphical View of Domain Structure and UniProtKB/Swiss-Prot for TMEM262 Gene

Function for TMEM262 Gene

Phenotypes From GWAS Catalog for TMEM262 Gene

Gene Ontology (GO) - Molecular Function for TMEM262 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005515 protein binding IPI 32296183
genes like me logo Genes that share ontologies with TMEM262: view

Inhibitory RNAs for research

  • Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for TMEM262

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for TMEM262 Gene

Localization for TMEM262 Gene

Subcellular locations from UniProtKB/Swiss-Prot for TMEM262 Gene

Membrane. Multi-pass membrane protein.

Subcellular locations from

COMPARTMENTS
Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for TMEM262 gene
Compartment Confidence
extracellular 2
mitochondrion 1
nucleus 1

Gene Ontology (GO) - Cellular Components for TMEM262 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0016020 membrane IEA --
GO:0016021 integral component of membrane IEA --
genes like me logo Genes that share ontologies with TMEM262: view

No data available for Subcellular locations from the Human Protein Atlas (HPA) for TMEM262 Gene

Pathways & Interactions for TMEM262 Gene

PathCards logo

SuperPathways for TMEM262 Gene

No Data Available

Gene Ontology (GO) - Biological Process for TMEM262 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for TMEM262 Gene

Drugs & Compounds for TMEM262 Gene

No Compound Related Data Available

Transcripts for TMEM262 Gene

mRNA/cDNA for TMEM262 Gene

2 REFSEQ mRNAs :
5 NCBI additional mRNA sequence :
6 Ensembl transcripts including schematic representations, and UCSC links to gene/alias where relevant :

Inhibitory RNAs for research

  • Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for TMEM262

Alternative Splicing Database (ASD) splice patterns (SP) for TMEM262 Gene

No ASD Table

Relevant External Links for TMEM262 Gene

GeneLoc Exon Structure for
TMEM262

Expression for TMEM262 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and SAGE for TMEM262 Gene

mRNA differential expression in normal tissues according to GTEx for TMEM262 Gene

This gene is overexpressed in Testis (x46.6).

Transcriptomic regulation report from SPP (The Signaling Pathways Project) for TMEM262

Evidence on tissue expression from TISSUES for TMEM262 Gene

  • Liver(2.5)
genes like me logo Genes that share expression patterns with TMEM262: view

Primer products for research

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt and Phenotype-based relationships between genes and organs from Gene ORGANizer for TMEM262 Gene

Orthologs for TMEM262 Gene

This gene was present in the common ancestor of mammals.

Orthologs for TMEM262 Gene

Organism Taxonomy Gene Similarity Type Details
Chimpanzee
(Pan troglodytes)
Mammalia TMEM262 31
  • 99 (a)
OneToOne
Cow
(Bos Taurus)
Mammalia LOC788530 30
  • 86.01 (n)
Rat
(Rattus norvegicus)
Mammalia Tmem262 30
  • 79.65 (n)
Mouse
(Mus musculus)
Mammalia BC048609 30 31
  • 78.17 (n)
OneToOne
Tmem262 17
Dog
(Canis familiaris)
Mammalia TMEM262 31
  • 78 (a)
OneToOne
Species where no ortholog for TMEM262 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Eremothecium gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • Alpha proteobacteria (Wolbachia pipientis)
  • Amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • Baker's yeast (Saccharomyces cerevisiae)
  • Barley (Hordeum vulgare)
  • Beta proteobacteria (Neisseria meningitidis)
  • Bread mold (Neurospora crassa)
  • Chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • Common water flea (Daphnia pulex)
  • Corn (Zea mays)
  • E. coli (Escherichia coli)
  • Filamentous fungi (Aspergillus nidulans)
  • Firmicute Bacteria (Streptococcus pneumoniae)
  • Fission Yeast (Schizosaccharomyces pombe)
  • Fruit Fly (Drosophila melanogaster)
  • Green Algae (Chlamydomonas reinhardtii)
  • Honey Bee (Apis mellifera)
  • K. Lactis Yeast (Kluyveromyces lactis)
  • Lizard (Anolis carolinensis)
  • Loblloly Pine (Pinus taeda)
  • Malaria Parasite (Plasmodium falciparum)
  • Medicago Trunc (Medicago Truncatula)
  • Moss (Physcomitrella patens)
  • Oppossum (Monodelphis domestica)
  • Orangutan (Pongo pygmaeus)
  • Pig (Sus scrofa)
  • Platypus (Ornithorhynchus anatinus)
  • Rainbow Trout (Oncorhynchus mykiss)
  • Rice (Oryza sativa)
  • Rice Blast Fungus (Magnaporthe grisea)
  • Schistosome Parasite (Schistosoma mansoni)
  • Sea Anemone (Nematostella vectensis)
  • Sea Vase (Ciona intestinalis)
  • Sea Squirt (Ciona savignyi)
  • Sea Urchin (Strongylocentrotus purpuratus)
  • Sorghum (Sorghum bicolor)
  • Soybean (Glycine max)
  • Stem Rust Fungus (Puccinia graminis)
  • Sugarcane (Saccharum officinarum)
  • Thale Cress (Arabidopsis thaliana)
  • Tomato (Lycopersicon esculentum)
  • Toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • Tropical Clawed Frog (Silurana tropicalis)
  • Wheat (Triticum aestivum)
  • Worm (Caenorhabditis elegans)
  • Zebrafish (Danio rerio)

Evolution for TMEM262 Gene

ENSEMBL:
Gene Tree for TMEM262 (if available)
TreeFam:
Gene Tree for TMEM262 (if available)
Aminode:
Evolutionary constrained regions (ECRs) for TMEM262: view image

Paralogs for TMEM262 Gene

(1) SIMAP similar genes for TMEM262 Gene using alignment to 1 proteins:

  • TM262_HUMAN
genes like me logo Genes that share paralogs with TMEM262: view

No data available for Paralogs for TMEM262 Gene

Variants for TMEM262 Gene

dbSNP identifiers (rs#s) for variants without ClinVar clinical significance for TMEM262 Gene

All consequence types are included: molecular consequences (e.g. missense, synonymous), and location-based (e.g. intron, upstream).

Structural Variations from Database of Genomic Variants (DGV) for TMEM262 Gene

Variant ID Type Subtype PubMed ID
nsv526181 CNV gain 19592680

Variation tolerance for TMEM262 Gene

Gene Damage Index Score: 8.84; 86.93% of all genes are more intolerant (likely to be disease-causing)

Additional Variant Information for TMEM262 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
TMEM262

SNP Genotyping and Copy Number Assays for research

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Sequence variations, with clinical significance, from ClinVar and Humsavar, with links to dbSNP for TMEM262 Gene

Disorders for TMEM262 Gene

Additional Disease Information for TMEM262

No disorders were found for TMEM262 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for TMEM262 Gene

Publications for TMEM262 Gene

  1. A reference map of the human binary protein interactome. (PMID: 32296183) Luck K … Calderwood MA (Nature 2020) 3
  2. Human chromosome 11 DNA sequence and analysis including novel gene identification. (PMID: 16554811) Taylor TD … Sakaki Y (Nature 2006) 4
  3. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T … Sugano S (Nature genetics 2004) 3

Products for TMEM262 Gene

Sources for TMEM262 Gene